Works matching AU Bohn, Laura M.

Results: 30

Mice lacking the norepinephrine transporter are supersensitive to psychostimulants.

Published in:

Nature Neuroscience, 2000, v. 3, n. 5, p. 465, doi. 10.1038/74839

By:

Xu, Fei;
Gainetdinov, Raul R.;
Wetsel, William C.;
Jones, Sara R.;
Bohn, Laura M.;
Miller, Gary W.;
Wang, Yan-Min;
Caron, Marc G.

Publication type:

Article

G protein signaling--biased agonism at the κ-opioid receptor is maintained in striatal neurons.

Published in:

Science Signaling, 2018, v. 11, n. 542, p. 1, doi. 10.1126/scisignal.aar4309

By:

Ho, Jo-Hao;
Stahl, Edward L.;
Schmid, Cullen L.;
Scarry, Sarah M.;
Aubé, Jeffrey;
Bohn, Laura M.

Publication type:

Article

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria.

Published in:

Science Signaling, 2016, v. 9, n. 456, p. 1, doi. 10.1126/scisignal.aai8441

By:

Brust, Tarsis F.;
Morgenweck, Jenny;
Kim, Susy A.;
Rose, Jamie H.;
Locke, Jason L.;
Schmid, Cullen L.;
Lei Zhou;
Stahl, Edward L.;
Cameron, Michael D.;
Scarry, Sarah M.;
Aubé, Jeffrey;
Jones, Sara R.;
Martin, Thomas J.;
Bohn, Laura M.

Publication type:

Article

RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.

Published in:

Science Signaling, 2016, v. 9, n. 454, p. 1, doi. 10.1126/scisignal.aaf6670

By:

Shahani, Neelam;
Swarnkar, Supriya;
Giovinazzo, Vincenzo;
Morgenweck, Jenny;
Bohn, Laura M.;
Scharager-Tapia, Catherina;
Pascal, Bruce;
Martinez-Acedo, Pablo;
Khare, Kshitij;
Subramaniam, Srinivasa

Publication type:

Article

Enhanced Rewarding Properties of Morphine, but not Cocaine, in βarrestin-2 Knock-Out Mice.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 32, p. 10265, doi. 10.1523/JNEUROSCI.23-32-10265.2003

By:

Bohn, Laura M.;
Gainetdinov, Raul R.;
Sotnikova, Tatyana D.;
Medvedev, Ivan O.;
Lefkowitz, Robert J.;
Dykstra, Linda A.;
Caron, Marc G.

Publication type:

Article

Irreversible and noncompetitive mu opioid receptor agonists.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R1962

By:

Stahl, Edward;
Schmid, Cullen L.;
Acevedo‐Canabal, Agnes;
Read, Cai;
Grim, Travis;
Kennedy, Nicole M.;
Bannister, Thomas D.;
Bohn, Laura M.

Publication type:

Article

Development of functionally selective agonists at the kappa opioid receptor (KOR).

Published in:

FASEB Journal, 2013, v. 27, p. lb551, doi. 10.1096/fasebj.27.1_supplement.lb551

By:

Lovell, Kimberly M;
Zhou, Lei;
Frankowski, Kevin J;
Slauson, Stephen R;
Streicher, John M;
Phillips, Angela;
Prisinzano, Thomas E;
Aube, Jeffrey;
Bohn, Laura M

Publication type:

Article

The atypical antipsychotic clozapine induces 5‐HT2ARmediated signaling and behavioral events in a beta‐arrestin2‐ independent but Akt‐dependent manner.

Published in:

FASEB Journal, 2013, v. 27, p. 1171.7, doi. 10.1096/fasebj.27.1_supplement.1171.7

By:

Schmid, Cullen L;
Streicher, John M;
Bohn, Laura M

Publication type:

Article

Development of biased agonists at the kappa opioid receptor.

Published in:

FASEB Journal, 2013, v. 27, p. 1171.3, doi. 10.1096/fasebj.27.1_supplement.1171.3

By:

Phillips, Angela;
Zhou, Lei;
Lovell, Kimberly;
Frankowski, Kevin;
Slausen, Stephen;
Prisinzano, Thomas E;
Aube, Jeff;
Bohn, Laura M

Publication type:

Article

Mu opioid receptor activation without arrestin-interactions; a pharmacological approach.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A426

By:

Bohn, Laura M.;
Groer, Chad E.;
Tidgewell, Kevin;
Moyer, Robert;
Harding, Wayne W.;
Prisinzano, Thomas E.

Publication type:

Article

Comparison of Agonist Activity between CB1 and CB2 Receptors with Orthosteric Site Mutations.

Published in:

Receptors, 2024, v. 3, n. 3, p. 380, doi. 10.3390/receptors3030018

By:

Brust, Christina A.;
Swanson, Matthew A.;
Tsoutsouvas, Christos Iliopoulos;
Dimova, Snezana T.;
Dang, Vuong Q.;
Stahl, Edward L.;
Ho, Jo-Hao;
Nikas, Spyros P.;
Makriyannis, Alexandros;
Bohn, Laura M.

Publication type:

Article

Lubiprostone reverses the inhibitory action of morphine on mucosal secretion in human small intestine.

Published in:

2011

By:

Sun, Xiaohong;
Wang, Xiyu;
Wang, Guo-Du;
Xia, Yun;
Liu, Sumei;
Qu, Meihua;
Needleman, Bradley;
Mikami, Dean;
Scott Melvin, W.;
Bohn, Laura;
Ueno, Ryuji;
Wood, Jackie;
Needleman, Bradley J;
Mikami, Dean J;
Melvin, W Scott;
Bohn, Laura M;
Wood, Jackie D

Publication type:

journal article

Recruitment of β-Arrestin into Neuronal Cilia Modulates Somatostatin Receptor Subtype 3 Ciliary Localization.

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 1, p. 223, doi. 10.1128/MCB.00765-15

By:

Green, Jill A.;
Schmid, Cullen L.;
Bley, Elizabeth;
Monsma, Paula C.;
Brown, Anthony;
Bohn, Laura M.;
Mykytyn, Kirk

Publication type:

Article

Recruitment of β-Arrestin into Neuronal Cilia Modulates Somatostatin Receptor Subtype 3 Ciliary Localization.

Published in:

Molecular & Cellular Biology, 2015, v. 35, n. 24, p. 223, doi. 10.1128/MCB.00765-15

By:

Green, Jill A.;
Schmid, Cullen L.;
Bley, Elizabeth;
Monsma, Paula C.;
Brown, Anthony;
Bohn, Laura M.;
Mykytyn, Kirk

Publication type:

Article

Clozapine Acts as an Agonist at Serotonin 2A Receptors to Counter MK-801-Induced Behaviors through a βArrestin2-Independent Activation of Akt.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 8, p. 1902, doi. 10.1038/npp.2014.38

By:

Schmid, Cullen L;
Streicher, John M;
Meltzer, Herbert Y;
Bohn, Laura M

Publication type:

Article

Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 935, doi. 10.3390/biom13060935

By:

Acevedo-Canabal, Agnes;
Grim, Travis W.;
Schmid, Cullen L.;
McFague, Nina;
Stahl, Edward L.;
Kennedy, Nicole M.;
Bannister, Thomas D.;
Bohn, Laura M.

Publication type:

Article

Mitogenic Signaling via Endogenous κ-Opioid Receptors in C6 Glioma Cells.

Published in:

Journal of Neurochemistry, 2000, v. 74, n. 2, p. 564, doi. 10.1046/j.1471-4159.2000.740564.x

By:

Bohn, Laura M.;
Belcheva, Mariana M.;
Coscia, Carmine J.

Publication type:

Article

μ-Opioid Agonist Inhibition of κ-Opioid Receptor-Stimulated Extracellular Signal-Regulated Kinase Phosphorylation Is Dynamin-Dependent in C6 Glioma Cells.

Published in:

Journal of Neurochemistry, 2000, v. 74, n. 2, p. 574, doi. 10.1046/j.1471-4159.2000.740574.x

By:

Bohn, Laura M.;
Belcheva, Mariana M.;
Coscia, Carmine J.

Publication type:

Article

Evidence for κ- and μ-Opioid Receptor Expression in C6 Glioma Cells.

Published in:

Journal of Neurochemistry, 1998, v. 70, n. 5, p. 1819, doi. 10.1046/j.1471-4159.1998.70051819.x

By:

Bohn, Laura M.;
Belcheva, Mariana M.;
Coscia, Carmine J.

Publication type:

Article

Serotonin receptor signaling and regulation via β-arrestins.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2010, v. 45, n. 6, p. 555, doi. 10.3109/10409238.2010.516741

By:

Bohn, Laura M.;
Schmid, Cullen L.

Publication type:

Article

κ-Opioid receptor binding varies inversely with tumor grade in human gliomas.

Published in:

Cancer (0008543X), 1998, v. 83, n. 12, p. 2561, doi. 10.1002/(SICI)1097-0142(19981215)83:12<2561::AID-CNCR23>3.0.CO;2-H

By:

Pan, Eric C.;
Bohn, Laura M.;
Belcheva, Mariana M.;
Thomas, Gail E.;
Manepalli, Anantha N.;
Mamone, James Y.;
Johnson, Frank E.;
Coscia, Carmine J.

Publication type:

Article

Kappa opioids promote the proliferation of astrocytes via Gβγ and β-arrestin 2-dependent MAPK-mediated pathways.

Published in:

Journal of Neurochemistry, 2008, v. 107, n. 6, p. 1753, doi. 10.1111/j.1471-4159.2008.05745.x

By:

McLennan, Gregory P.;
Kiss, Alexi;
Miyatake, Mayumi;
Belcheva, Mariana M.;
Chambers, Kari T.;
Pozek, John J.;
Mohabbat, Yasmin;
Moyer, Robert A.;
Bohn, Laura M.;
Coscia, Carmine J.

Publication type:

Article

[mu]-Opioid receptor desensitization by [beta]-arrestin-2 determines morphine tolerance but not dependence.

Published in:

Nature, 2000, v. 408, n. 6813, p. 720, doi. 10.1038/35047086

By:

Bohn, Laura M.;
Gainetdinov, Raul R.;
Lin, Fang-Tsyr;
Lefkowitz, Robert J.;
Caron, Marc G.

Publication type:

Article

Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice.

Published in:

Psychopharmacology, 2005, v. 180, n. 3, p. 408, doi. 10.1007/s00213-005-2173-y

By:

Medvedev, Ivan O.;
Gainetdinov, Raul R.;
Sotnikova, Tatyana D.;
Bohn, Laura M.;
Caron, Marc G.;
Dykstra, Linda A.

Publication type:

Article

Community guidelines for GPCR ligand bias: IUPHAR review 32.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3651, doi. 10.1111/bph.15811

By:

Kolb, Peter;
Kenakin, Terry;
Alexander, Stephen P. H.;
Bermudez, Marcel;
Bohn, Laura M.;
Breinholt, Christian S.;
Bouvier, Michel;
Hill, Stephen J.;
Kostenis, Evi;
Martemyanov, Kirill A.;
Neubig, Rick R.;
Onaran, H. Ongun;
Rajagopal, Sudarshan;
Roth, Bryan L.;
Selent, Jana;
Shukla, Arun K.;
Sommer, Martha E.;
Gloriam, David E.

Publication type:

Article

Structural and functional insights into the G protein-coupled receptors: CB1 and CB2.

Published in:

Biochemical Society Transactions, 2023, v. 51, n. 4, p. 1533, doi. 10.1042/BST20221316

By:

Brust, Christina A.;
Swanson, Matthew A.;
Bohn, Laura M.

Publication type:

Article

Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans.

Published in:

G3: Genes | Genomes | Genetics, 2016, v. 6, n. 6, p. 1695, doi. 10.1534/g3.116.026997

By:

Rodrigues, Pedro Reis;
Kaul, Tiffany K.;
Jo-Hao Ho;
Lucanic, Mark;
Burkewitz, Kristopher;
Mair, William B.;
Held, Jason M.;
Bohn, Laura M.;
Gill, Matthew S.

Publication type:

Article

Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.

Published in:

Nature Chemistry, 2011, v. 3, n. 6, p. 449, doi. 10.1038/nchem.1050

By:

Tarselli, Michael A.;
Raehal, Kirsten M.;
Brasher, Alex K.;
Streicher, John M.;
Groer, Chad E.;
Cameron, Michael D.;
Bohn, Laura M.;
Micalizio, Glenn C.

Publication type:

Article

A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) μ-opioid agonists on cellular markers related to opioid tolerance and dependence.

Published in:

Synapse, 2007, v. 61, n. 3, p. 166, doi. 10.1002/syn.20356

By:

Xu, Heng;
Partilla, John S.;
Wang, Xiaoying;
Rutherford, John M.;
Tidgewell, Kevin;
Prisinzano, Thomas E.;
Bohn, Laura M.;
Rothman, Richard B.

Publication type:

Article

Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 40, p. 13513, doi. 10.1523/JNEUROSCI.1665-10.2010

By:

Schmid, Cullen L.;
Bohn, Laura M.

Publication type:

Article