Works matching AU Blanck, George

Results: 74

Recovery of T-cell receptor V(D)J recombination reads from lower grade glioma exome files correlates with reduced survival and advanced cancer grade.

Published in:

Journal of Neuro-Oncology, 2018, v. 140, n. 3, p. 697, doi. 10.1007/s11060-018-03001-1

By:

Chobrutskiy, Boris I.;
Zaman, Saif;
Tong, Wei Lue;
Diviney, Andrea;
Blanck, George

Publication type:

Article

IGL CDR3 Hydropathy and Antigen Chemical Complementarity Associated with Greater Disease-Free Survival in Lung Adenocarcinoma: Implications for Gender Disparities.

Published in:

Biochemical Genetics, 2024, v. 62, n. 1, p. 530, doi. 10.1007/s10528-023-10437-2

By:

Charkowick, Shaun V.;
Huda, Taha I.;
Patel, Dhruv N.;
Yeagley, Michelle;
Arturo, Juan F.;
Cios, Konrad J.;
Gozlan, Etienne C.;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I.;
Blanck, George

Publication type:

Article

B-cell ALL with SOX11 gene amplification associates with a worse outcome.

Published in:

Cell Cycle, 2024, v. 23, n. 1, p. 36, doi. 10.1080/15384101.2024.2306756

By:

Angelakakis, George;
Varkhedi, Mallika;
Dabkowski, Toriana R.;
Diaz, Michael J.;
Yeagley, Michelle;
Blanck, George

Publication type:

Article

MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma.

Published in:

Cell Cycle, 2018, v. 17, n. 21/22, p. 2474, doi. 10.1080/15384101.2018.1542898

By:

Zaman, Saif;
Chobrutskiy, Boris I.;
Blanck, George

Publication type:

Article

TCGA: Increased oncoprotein coding region mutations correlate with a greater expression of apoptosis-effector genes and a positive outcome for stomach adenocarcinoma.

Published in:

Cell Cycle, 2016, v. 15, n. 16, p. 2157, doi. 10.1080/15384101.2016.1195532

By:

Yavorski, John M.;
Blanck, George

Publication type:

Article

Impact of SNPs on CpG Islands in the MYC and HRAS oncogenes and in a wide variety of tumor suppressor genes: A multi-cancer approach.

Published in:

Cell Cycle, 2016, v. 15, n. 12, p. 1572, doi. 10.1080/15384101.2016.1164360

By:

Samy, Mohammad D.;
Yavorski, John M.;
Mauro, James A.;
Blanck, George

Publication type:

Article

Tumor suppressor genes are larger than apoptosis-effector genes and have more regions of active chromatin: Connection to a stochastic paradigm for sequential gene expression programs.

Published in:

Cell Cycle, 2015, v. 14, n. 15, p. 2494, doi. 10.1080/15384101.2015.1044179

By:

Garcia, Marlene;
Mauro, James A;
Ramsamooj, Michael;
Blanck, George

Publication type:

Article

TRB CDR3-cancer testis antigen chemical complementarity scoring for identifying productive immune responses in renal cell carcinoma.

Published in:

Cancer Biomarkers, 2023, v. 38, n. 1, p. 103, doi. 10.3233/CBM-230047

By:

Hudock, Tabitha R.;
Barker, Vayda R.;
Manley, Brandon J.;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I.;
Diaz, Michael J.;
Song, Joanna J.;
Blanck, George

Publication type:

Article

Immunoscoring by correlating MHC class II and TCR expression: high level immune functions represented by the KIRP dataset of TCGA.

Published in:

Cell & Tissue Research, 2016, v. 363, n. 2, p. 491, doi. 10.1007/s00441-015-2261-1

By:

Butler, Shanitra;
Blanck, George

Publication type:

Article

Immune receptor CDR3 chemical features that preserve sequence information are highly efficient in reflecting survival distinctions: A pan-cancer analysis.

Published in:

Biomedical Reports, 2022, v. 17, n. 2, p. N.PAG, doi. 10.3892/br.2022.1551

By:

Mcbreairty, Brooke E.;
Chobrutskiy, Boris I.;
Chobrutskiy, Andrea;
Gozlan, Etienne C.;
Diaz, Michael J.;
Blanck, George

Publication type:

Article

Protected cytoskeletal‑related proteins: Towards a resolution of contradictions regarding the role of the cytoskeleton in cancer.

Published in:

Biomedical Reports, 2017, v. 7, n. 2, p. 163, doi. 10.3892/br.2017.940

By:

SEGARRA, DANIEL T.;
YAVORSKI, JOHN M.;
BLANCK, GEORGE

Publication type:

Article

De novo, systemic, deleterious amino acid substitutions are common in large cytoskeleton-related protein coding regions.

Published in:

Biomedical Reports, 2017, v. 6, n. 2, p. 211, doi. 10.3892/br.2016.826

By:

STOLL, REBECCA J.;
THOMPSON, GRACE R.;
SAMY, MOHAMMAD D.;
BLANCK, GEORGE

Publication type:

Article

Chemical Complementarity of Breast Cancer Resident, T-Cell Receptor CDR3 Domains and the Cancer Antigen, ARMC3, is Associated With Higher Levels of Survival and Granzyme Expression.

Published in:

Cancer Informatics, 2023, p. 1, doi. 10.1177/11769351231177269

By:

Pakasticali, Nagehan;
Chobrutskiy, Andrea;
Patel, Dhruv N.;
Hsiang, Monica;
Zaman, Saif;
Cios, Konrad J.;
Blanck, George;
Chobrutskiy, Boris I.

Publication type:

Article

Chemical Complementarity of Breast Cancer Resident, T-Cell Receptor CDR3 Domains and the Cancer Antigen, ARMC3, is Associated With Higher Levels of Survival and Granzyme Expression.

Published in:

Cancer Informatics, 2023, v. 22, p. 1, doi. 10.1177/11769351231177269

By:

Pakasticali, Nagehan;
Chobrutskiy, Andrea;
Patel, Dhruv N.;
Hsiang, Monica;
Zaman, Saif;
Cios, Konrad J.;
Blanck, George;
Chobrutskiy, Boris I.

Publication type:

Article

Detection of Productively Rearranged TcR-α V-J Sequences in TCGA Exome Files: Implications for Tumor Immunoscoring and Recovery of Antitumor T-cells.

Published in:

Cancer Informatics, 2016, n. 15, p. 23, doi. 10.4137/CIN.S35784

By:

Gill, Thomas R.;
Samy, Mohammad D.;
Butler, Shanitra N.;
Mauro, James A.;
Sexton, Wade J.;
Blanck, George

Publication type:

Article

Bacterial Sequencing Reads in Blood Exome Files from Melanoma and Cervical Cancer Patients are Associated with Cancer Recurrence.

Published in:

Molecular Biotechnology, 2023, v. 65, n. 9, p. 1476, doi. 10.1007/s12033-023-00663-9

By:

Quach, Jessica U.;
Diaz, Michael J.;
Huda, Taha I.;
Kinskey, Jacob C.;
Zaman, Saif;
Desantis, John E.;
Cios, Konrad J.;
Blanck, George

Publication type:

Article

High-throughput quantitative assessments of the chemical complementarity of celiac disease-related IGH CDR3s and a gliadin epitope.

Published in:

International Immunology, 2024, v. 36, n. 9, p. 465, doi. 10.1093/intimm/dxae025

By:

Jain, Rahul;
Bressler, Max;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I;
Blanck, George

Publication type:

Article

TcR-α recombinations in renal cell carcinoma exome files correlate with an intermediate level of T-cell exhaustion biomarkers.

Published in:

International Immunology, 2018, v. 30, n. 1, p. 35, doi. 10.1093/intimm/dxx074

By:

Mai, Anne T.;
Tong, Wei Lue;
Tu, Yaping N.;
Blanck, George

Publication type:

Article

Specific TCR V–J gene segment recombinations leading to the identification pan-V–J CDR3s associated with survival distinctions: diffuse large B-cell lymphoma.

Published in:

Leukemia & Lymphoma, 2022, v. 63, n. 6, p. 1314, doi. 10.1080/10428194.2021.2020781

By:

Cios, Konrad J.;
Huda, Taha I.;
Eakins, Rachel A.;
Mihyu, Moody M.;
Blanck, George

Publication type:

Article

Specific HLA alleles, paired with TCR V- and J-gene segment usage, link to distinct multiple myeloma survival rates.

Published in:

Leukemia & Lymphoma, 2021, v. 62, n. 7, p. 1711, doi. 10.1080/10428194.2021.1885655

By:

Huda, Taha I.;
Mihyu, Moody;
Gozlan, Etienne C.;
Arndt, Mary F.;
Diaz, Michael J.;
Zaman, Saif;
Chobrutskiy, Boris I.;
Blanck, George

Publication type:

Article

The Rise of the Biomedical Sciences Master's Program at U.S. Medical Colleges.

Published in:

Teaching & Learning in Medicine, 2014, v. 26, n. 4, p. 409, doi. 10.1080/10401334.2014.910122

By:

Blanck, George

Publication type:

Article

The human, F-actin-based cytoskeleton as a mutagen sensor.

Published in:

Cancer Cell International, 2017, v. 17, p. 1, doi. 10.1186/s12935-017-0488-5

By:

Clark, Nicolette M.;
Garcia Galindo, Carlos A.;
Patel, Vandan K.;
Parry, Michele L.;
Stoll, Rebecca J.;
Yavorski, John M.;
Pinkason, Elizabeth P.;
Johnson, Edna M.;
Walker, Chelsea M.;
Johnson, Joseph;
Sexton, Wade J.;
Coppola, Domenico;
Blanck, George

Publication type:

Article

TRB‐J1 usage, in combination with the HLA‐A*01:01 allele, represents an apparent survival advantage for uterine corpus endometrial carcinoma: Comparisons with microscopic assessments of lymphocyte infiltrates.

Published in:

International Journal of Immunogenetics, 2019, v. 46, n. 1, p. 31, doi. 10.1111/iji.12409

By:

Clark, Kendall R.;
Tong, Wei Lue;
Callahan, Blake M.;
Yavorski, John M.;
Tu, Yaping N.;
Blanck, George

Publication type:

Article

Identification of immunoglobulin V(D)J recombinations in solid tumor specimen exome files: Evidence for high level B-cell infiltrates in breast cancer.

Published in:

Human Vaccines & Immunotherapeutics, 2017, v. 13, n. 3, p. 501, doi. 10.1080/21645515.2016.1246095

By:

Tong, Wei Lue;
Tu, Yaping N.;
Samy, Mohammad D.;
Sexton, Wade J.;
Blanck, George

Publication type:

Article

HLA-DR peptide occupancy can be regulated with a wide variety of small molecules.

Published in:

Human Vaccines & Immunotherapeutics, 2016, v. 12, n. 3, p. 593, doi. 10.1080/21645515.2015.1089370

By:

Blazekovic, Francesca;
Odukoya, Dana;
Butler, Shanitra N.;
Mauro, James A.;
Ramsamooj, Michael;
Puleo, Erika;
Szekeres, Karoly;
Dana, Dibyendu;
Kumar, Sanjai;
Ragupathi, Govind;
Blanck, George

Publication type:

Article

Flat cells come full sphere: Are mutant cytoskeletal-related proteins oncoprotein-monsters or useful immunogens?

Published in:

Human Vaccines & Immunotherapeutics, 2016, v. 12, n. 1, p. 120, doi. 10.1080/21645515.2015.1073428

By:

Parry, Michele L;
Blanck, George

Publication type:

Article

The future of cancer research.

Published in:

Human Vaccines & Immunotherapeutics, 2014, v. 10, n. 3, p. 1, doi. 10.4161/hv.27458

By:

Blanck, George

Publication type:

Article

Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors.

Published in:

Human Vaccines & Immunotherapeutics, 2013, v. 9, n. 4, p. 1, doi. 10.4161/hv.23085

By:

Cronin, Kevin;
Escobar, Hernando;
Szekeres, Karoly;
Reyes-Vargas, Eduardo;
Rockwood, Alan L.;
Lloyd, Mark C.;
Delgado, Julio C.;
Blanck, George

Publication type:

Article

RB and A novel E2F-1 binding protein in MHC class II deficient B-cell lines and normal IFN-γ induction of the class II transactivator ciita in class II non-inducible RB-defective tumor lines.

Published in:

International Journal of Cancer, 1995, v. 62, n. 4, p. 461, doi. 10.1002/ijc.2910620417

By:

Tschickardt, Michael E.;
Lu, Yanmei;
Jacim, Mark;
de Wayne Ussery, G.;
Steimle, Viktor;
Mach, Bernard;
Blanck, George

Publication type:

Article

Blood-based T cell receptor anti-viral CDR3s are associated with worse overall survival for neuroblastoma.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 13, p. 12047, doi. 10.1007/s00432-023-05059-5

By:

Kacsoh, Dorottya B.;
Diaz, Michael J.;
Gozlan, Etienne C.;
Sahoo, Arpan;
Song, Joanna J.;
Yeagley, Michelle;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I.;
Blanck, George

Publication type:

Article

Delineation of a T-cell receptor CDR3-cancer mutanome aromaticity factor, assessable via blood samples, that facilitates the establishment of survival distinctions in bladder cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 8, p. 4359, doi. 10.1007/s00432-022-04339-w

By:

Waweru, Jacqueline Wahura;
Mwangi, Kennedy Wanjau;
Barker, Vayda R.;
Gozlan, Etienne C.;
Yeagley, Michelle;
Blanck, George;
Makokha, Francis W.

Publication type:

Article

T-cell receptor-α CDR3 domain chemical features correlate with survival rates in bladder cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2019, v. 145, n. 3, p. 615, doi. 10.1007/s00432-018-2815-1

By:

Chobrutskiy, Boris I.;
Zaman, Saif;
Diviney, Andrea;
Mihyu, Moody M.;
Blanck, George

Publication type:

Article

Identification of specific feed-forward apoptosis mechanisms and associated higher survival rates for low grade glioma and lung squamous cell carcinoma.

Published in:

Journal of Cancer Research & Clinical Oncology, 2018, v. 144, n. 3, p. 459, doi. 10.1007/s00432-017-2569-1

By:

Sikaria, Dhiraj;
Tu, Yaping N.;
Fisler, Diana A.;
Mauro, James A.;
Blanck, George

Publication type:

Article

Substantially reduced expression of PIAS1 is associated with colon cancer development.

Published in:

Journal of Cancer Research & Clinical Oncology, 2009, v. 135, n. 9, p. 1287, doi. 10.1007/s00432-009-0570-z

By:

Coppola, Domenico;
Parikh, Vevek;
Boulware, David;
Blanck, George

Publication type:

Article

Interferon regulatory factor-2 point mutations in human pancreatic tumors.

Published in:

International Journal of Cancer, 2000, v. 87, n. 6, p. 803, doi. 10.1002/1097-0215(20000915)87:6<803::AID-IJC7>3.0.CO;2-E

By:

Xi, Hongkang;
Blanck, George

Publication type:

Article

A scoring system for the electrostatic complementarities of T‐cell receptors and cancer‐mutant amino acids: multi‐cancer analyses of associated survival rates.

Published in:

Immunology, 2020, v. 159, n. 4, p. 373, doi. 10.1111/imm.13165

By:

Chobrutskiy, Boris I.;
Yeagley, Michelle;
Diviney, Andrea;
Zaman, Saif;
Gozlan, Etienne C.;
Tipping, Price;
Koohestani, Darush M.;
Roca, Andrea M.;
Blanck, George

Publication type:

Article

TCR gene segment usage and HLA alleles that are associated with cancer survival rates also represent racial disparities.

Published in:

International Journal of Immunogenetics, 2023, v. 50, n. 2, p. 41, doi. 10.1111/iji.12610

By:

Angelakakis, George;
Serraneau, Karisa S.;
Barker, Vayda R.;
Callahan, Blake M.;
Tong, Wei Lue;
Zaman, Saif;
Huda, Taha I.;
Blanck, George

Publication type:

Article

A comparison of immune receptor recombination databases sourced from tumour exome or RNAseq files: Verifications of immunological distinctions between primary and metastatic melanoma.

Published in:

International Journal of Immunogenetics, 2021, v. 48, n. 5, p. 409, doi. 10.1111/iji.12550

By:

Patel, Dhruv N.;
Yeagley, Michelle;
Arturo, Juan F.;
Falasiri, Shayan;
Chobrutskiy, Boris I.;
Gozlan, Etienne C.;
Blanck, George

Publication type:

Article

T-cell receptor-β V and J usage, in combination with particular HLA class I and class II alleles, correlates with cancer survival patterns.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 6, p. 885, doi. 10.1007/s00262-018-2139-7

By:

Callahan, Blake M.;
Yavorski, John M.;
Tu, Yaping N.;
Tong, Wei Lue;
Kinskey, Jacob C.;
Clark, Kendall R.;
Fawcett, Timothy J.;
Blanck, George

Publication type:

Article

T cell receptor gene recombinations in human tumor specimen exome files: detection of T cell receptor-β VDJ recombinations associates with a favorable oncologic outcome for bladder cancer.

Published in:

Cancer Immunology, Immunotherapy, 2017, v. 66, n. 3, p. 403, doi. 10.1007/s00262-016-1943-1

By:

Samy, Mohammad;
Tong, Wei;
Yavorski, John;
Sexton, Wade;
Blanck, George

Publication type:

Article

Mutations and regulatory anomalies effecting tumor cell immune functions.

Published in:

Cancer Immunology, Immunotherapy, 2004, v. 53, n. 1, p. 1, doi. 10.1007/s00262-003-0418-3

By:

Blanck, George

Publication type:

Article

Electrostatic Complementarities of Glioblastoma-Resident T-Cell Receptors and Cancer Testis Antigens Linked to Poor Outcomes and High Levels of Sphingosine Kinase-2 Expression.

Published in:

Biology (2079-7737), 2023, v. 12, n. 4, p. 575, doi. 10.3390/biology12040575

By:

Arias, Miguel A.;
Cios, Konrad J.;
Kacsoh, Dorottya B.;
Montgomery, Bailey E.;
Song, Joanna J.;
Patel, Anishaa R.;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I.;
Blanck, George

Publication type:

Article

Cytoskeleton and ECM tumor mutant peptides: Increased protease sensitivities and potential consequences for the HLA class I mutant epitope reservoir.

Published in:

International Journal of Cancer, 2018, v. 142, n. 5, p. 988, doi. 10.1002/ijc.31111

By:

Callahan, Blake M.;
Patel, Jay S.;
Fawcett, Timothy J.;
Blanck, George

Publication type:

Article

Assessing microenvironment immunogenicity using tumor specimen exomes: Co-detection of TcR-α/β V(D)J recombinations correlates with PD-1 expression.

Published in:

International Journal of Cancer, 2017, v. 140, n. 11, p. 2568, doi. 10.1002/ijc.30675

By:

Tu, Yaping N.;
Tong, Wei Lue;
Samy, Mohammad D.;
Yavorski, John M.;
Kim, Minjung;
Blanck, George

Publication type:

Article

Better Outcomes for Ovarian Cancer Associated With the Detection of Anti‐EBV TCR CDR3s: Potential Relevance to Diffuse Large B‐Cell Lymphoma.

Published in:

American Journal of Reproductive Immunology, 2025, v. 93, n. 1, p. 1, doi. 10.1111/aji.70046

By:

Goel, Nandini;
Baker, Madeline C.;
Aboujaoude, Michael T.;
Diaz, Michael J.;
Jain, Rahul;
Huda, Taha I.;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I.;
Song, Joanna J.;
Vangala, Veda Naga Priya;
Blanck, George

Publication type:

Article

TCR CDR3‐antigen chemical complementarity associated with poor ovarian cancer outcomes: A vestigial immune response to early cancer antigens?

Published in:

American Journal of Reproductive Immunology, 2023, v. 89, n. 1, p. 1, doi. 10.1111/aji.13639

By:

Barker, Vayda R.;
Varkhedi, Mallika;
Patel, Dhruv N.;
Hsiang, Monica;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I.;
Blanck, George

Publication type:

Article

TRB CDR3 chemical complementarity with HBV epitopes correlates with increased hepatocellular carcinoma, disease‐free survival.

Published in:

Journal of Medical Virology, 2023, v. 95, n. 8, p. 1, doi. 10.1002/jmv.29043

By:

Song, Joanna J.;
Chobrutskiy, Andrea;
Chobrutskiy, Boris I.;
Cios, Konrad J.;
Huda, Taha I.;
Eakins, Rachel A.;
Diaz, Michael J.;
Blanck, George

Publication type:

Article

Elucidating feed-forward apoptosis signatures in breast cancer datasets: Higher FOS expression associated with a better outcome.

Published in:

Oncology Letters, 2018, v. 16, n. 2, p. 2757, doi. 10.3892/ol.2018.8957

By:

Fisler, Diana A.;
Sikaria, Dhiraj;
Yavorski, John M.;
Tu, Yaping N.;
Blanck, George

Publication type:

Article

Overlap of the cancer genome atlas and the immune epitope database.

Published in:

Oncology Letters, 2016, v. 12, n. 4, p. 2982, doi. 10.3892/ol.2016.4991

By:

SAIT, SHAIMAA;
FAWCETT, TIMOTHY;
BLANCK, GEORGE

Publication type:

Article

MHC class II associated stomach cancer mutations correlate with lack of subsequent tumor development.

Published in:

Molecular & Clinical Oncology, 2017, v. 7, n. 6, p. 1119, doi. 10.3892/mco.2017.1432

By:

YAVORSKI, JOHN M.;
BLANCK, GEORGE

Publication type:

Article