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Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer.
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- Cancers, 2024, v. 16, n. 15, p. 2714, doi. 10.3390/cancers16152714
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- Article
Inhibiting spinal cord-specific hsp90 isoforms reveals a novel strategy to improve the therapeutic index of opioid treatment.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-65637-6
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- Article
Anti-inflammatory activities of novel heat shock protein 90 isoform selective inhibitors in BV-2 microglial cells.
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- Frontiers in Molecular Biosciences, 2024, p. 1, doi. 10.3389/fmolb.2024.1405339
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- Article
Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target.
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- Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1282855
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- Article
CryoEM Structure with ATP Synthase Enables Late-Stage Diversification of Cruentaren A.
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- Chemistry - A European Journal, 2023, v. 29, n. 29, p. 1, doi. 10.1002/chem.202300262
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- Article
The biology and inhibition of glucose‐regulated protein 94/gp96.
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- Medicinal Research Reviews, 2022, v. 42, n. 6, p. 2007, doi. 10.1002/med.21915
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- Article
Hsp90β inhibition upregulates interferon response and enhances immune checkpoint blockade therapy in murine tumors.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1005045
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- Article
Structure‐Based Design, Synthesis, and Biological Evaluation of Hsp90β‐Selective Inhibitors.
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- Chemistry - A European Journal, 2021, v. 27, n. 59, p. 14747, doi. 10.1002/chem.202102574
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- Article
Selective Inhibition of the Hsp90α Isoform.
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- Angewandte Chemie, 2021, v. 133, n. 19, p. 10641, doi. 10.1002/ange.202015422
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- Article
Selective Inhibition of the Hsp90α Isoform.
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- Angewandte Chemie International Edition, 2021, v. 60, n. 19, p. 10547, doi. 10.1002/anie.202015422
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- Article
The role and therapeutic potential of Hsp90, Hsp70, and smaller heat shock proteins in peripheral and central neuropathies.
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- Medicinal Research Reviews, 2021, v. 41, n. 1, p. 202, doi. 10.1002/med.21729
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- Article
Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6898, doi. 10.3390/ijms21186898
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- Article
Novel C‐terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self‐renewal, and epithelial–mesenchymal transition.
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- Molecular Oncology, 2020, v. 14, n. 9, p. 2058, doi. 10.1002/1878-0261.12686
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- Article
Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway.
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- Science Signaling, 2020, v. 13, n. 630, p. 1, doi. 10.1126/scisignal.aaz1854
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- Article
The Alpha Isoform of Heat Shock Protein 90 and the Co-chaperones p23 and Cdc37 Promote Opioid Anti-nociception in the Brain.
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- Frontiers in Molecular Neuroscience, 2019, v. 12, p. 1, doi. 10.3389/fnmol.2019.00294
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- Article
Cover Feature: Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C-Terminal Inhibitors (ChemMedChem 24/2017).
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- ChemMedChem, 2017, v. 12, n. 24, p. 2015, doi. 10.1002/cmdc.201700751
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- Article
Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C-Terminal Inhibitors.
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- ChemMedChem, 2017, v. 12, n. 24, p. 2022, doi. 10.1002/cmdc.201700630
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- Article
Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C-terminal Inhibitors.
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- Chemistry - A European Journal, 2017, v. 23, n. 65, p. 16574, doi. 10.1002/chem.201703206
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- Article
Second Generation Grp94-Selective Inhibitors Provide Opportunities for the Inhibition of Metastatic Cancer.
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- Chemistry - A European Journal, 2017, v. 23, n. 62, p. 15775, doi. 10.1002/chem.201703398
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- Article
Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.
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- Chemistry - A European Journal, 2016, v. 22, n. 20, p. 6921, doi. 10.1002/chem.201504955
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- Article
Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?
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- Medicinal Research Reviews, 2016, v. 36, n. 1, p. 92, doi. 10.1002/med.21351
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- Article
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma.
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- Human Molecular Genetics, 2014, v. 23, n. 24, p. 6470, doi. 10.1093/hmg/ddu367
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- Article
High-Throughput Screen of Natural Product Libraries for Hsp90 Inhibitors.
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- Biology (2079-7737), 2014, v. 3, n. 1, p. 101, doi. 10.3390/biology3010101
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- Article
Development of a High-Throughput Screening Cancer Cell-Based Luciferase Refolding Assay for Identifying Hsp90 Inhibitors.
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- Assay & Drug Development Technologies, 2013, v. 11, n. 8, p. 478, doi. 10.1089/adt.2012.498
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- Article
Novel C-Terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents.
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- Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2012, v. 19, p. 483, doi. 10.1245/s10434-011-1971-1
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- Article
KU-32, a Novel Drug for Diabetic Neuropathy, Is Safe for Human Islets and Improves In Vitro Insulin Secretion and Viability.
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- Experimental Diabetes Research, 2012, p. 1, doi. 10.1155/2012/671673
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- Article
A High-Throughput TNP-ATP Displacement Assay for Screening Inhibitors of ATP-Binding in Bacterial Histidine Kinases.
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- Assay & Drug Development Technologies, 2011, v. 9, n. 2, p. 174, doi. 10.1089/adt.2010.0289
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- Article
Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells.
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- Prostate, 2010, v. 70, n. 1, p. 27, doi. 10.1002/pros.21035
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- Article
Hsp90 as a Target for Drug Development.
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- ChemMedChem, 2006, v. 1, n. 12, p. 1331, doi. 10.1002/cmdc.200600112
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Hsp90 inhibitors: Small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation.
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- Medicinal Research Reviews, 2006, v. 26, n. 3, p. 310, doi. 10.1002/med.20052
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- Article