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Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes.
Published in:
2001
By:
- Schrauwen, Patrick;
- Hesselink, Matthijs K.C.;
- Blaak, Ellen E.;
- Borghouts, Lars B.;
- Schaart, Gert;
- Saris, Wim H.M.;
- Keizer, Hans A.;
- Schrauwen, P;
- Hesselink, M K;
- Blaak, E E;
- Borghouts, L B;
- Schaart, G;
- Saris, W H;
- Keizer, H A
Publication type:
journal article
Plasma free Fatty Acid uptake and oxidation are already diminished in subjects at high risk for developing type 2 diabetes.
Published in:
2001
By:
- Mensink, Marco;
- Blaak, Ellen E.;
- van Baak, Marleen A.;
- Wagenmakers, Anton J.M.;
- Saris, Wim H.M.;
- Mensink, M;
- Blaak, E E;
- van Baak, M A;
- Wagenmakers, A J;
- Saris, W H
Publication type:
journal article
Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise.
Published in:
2000
By:
- Blaak, Ellen E.;
- Blaak, E E;
- van Aggel-Leijssen, D P;
- Wagenmakers, A J;
- Saris, W H;
- van Baak, M A
Publication type:
journal article
Monocytes, but not T cells, respond to insulin with Akt(S473) phosphorylation independent of the donor glucometabolic state.
Published in:
Diabetes/Metabolism Research & Reviews, 2014, v. 30, n. 4, p. 323, doi. 10.1002/dmrr.2498
By:
- Thewissen, M. M.;
- Gaar, J.;
- Boer, A. Th.;
- Munsters, M. J.;
- Blaak, E. E.;
- Duijvestijn, A.
Publication type:
Article
Adipose tissue fatty acid metabolism in insulin-resistant men.
Published in:
2008
By:
- Bickerton, A.;
- Roberts, R.;
- Fielding, B.;
- Tornqvist, H.;
- Blaak, E.;
- Wagenmakers, A.;
- Gilbert, M.;
- Humphreys, S.;
- Karpe, F.;
- Frayn, K.
Publication type:
Correction Notice
Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients.
Published in:
Diabetologia, 2008, v. 51, n. 10, p. 1893, doi. 10.1007/s00125-008-1108-7
By:
- Boon, H.;
- Bosselaar, M.;
- Praet, S.;
- Blaak, E.;
- Saris, W.;
- Wagenmakers, A.;
- McGee, S.;
- Tack, C.;
- Smits, P.;
- Hargreaves, M.;
- Loon, L.
Publication type:
Article
Adipose tissue fatty acid metabolism in insulin-resistant men.
Published in:
Diabetologia, 2008, v. 51, n. 8, p. 1466, doi. 10.1007/s00125-008-1040-x
By:
- Bickerton, A.;
- Roberts, R.;
- Fielding, B.;
- Tornqvist, H.;
- Blaak, E.;
- Wagenmakers, A.;
- Gilbert, M.;
- Humphreys, S.;
- Karpe, F.;
- Frayn, K.
Publication type:
Article
Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men.
Published in:
Diabetologia, 2008, v. 51, n. 2, p. 320, doi. 10.1007/s00125-007-0866-y
By:
- Jocken, J.;
- Goossens, G.;
- Hees, A.;
- Frayn, K.;
- Baak, M.;
- Stegen, J.;
- Pakbiers, M.;
- Saris, W.;
- Blaak, E.
Publication type:
Article
Substrate source utilisation in long-term diagnosed type 2 diabetes patients at rest, and during exercise and subsequent recovery.
Published in:
Diabetologia, 2007, v. 50, n. 1, p. 103, doi. 10.1007/s00125-006-0482-2
By:
- Boon, H.;
- Blaak, E.;
- Saris, W.;
- Keizer, H.;
- Wagenmakers, A.;
- Loon, L.
Publication type:
Article
Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects.
Published in:
Diabetologia, 2006, v. 49, n. 12, p. 3009, doi. 10.1007/s00125-006-0458-2
By:
- Goossens, G. H.;
- Blaak, E. E.;
- Schiffers, P. P.;
- Saris, W. H. M.;
- van Baak, M. A.
Publication type:
Article
Major differences in noradrenaline action on lipolysis and blood flow rates in skeletal muscle and adipose tissue in vivo.
Published in:
Diabetologia, 2005, v. 48, n. 5, p. 946, doi. 10.1007/s00125-005-1708-4
By:
- Quisth, V.;
- Enoksson, S.;
- Blaak, E.;
- Hagström-Toft, E.;
- Arner, P.;
- Bolinder, J.
Publication type:
Article
Impaired β-adrenergically mediated lipolysis in skeletal muscle of obese subjects Muscle lipolysis in obesity.
Published in:
Diabetologia, 2004, v. 47, n. 8, p. 1462, doi. 10.1007/s00125-004-1471-y
By:
- Blaak, E. E.;
- Schiffelers, S. L.;
- Saris, W. H.;
- Mensink, M.;
- Kooi, M. E.
Publication type:
Article
Lifestyle changes and lipid metabolism gene expression and protein content in skeletal muscle of subjects with impaired glucose tolerance M. Mensink et al.: Lifestyle-changes and skeletal muscle gene expression.
Published in:
Diabetologia, 2003, v. 46, n. 8, p. 1082, doi. 10.1007/s00125-003-1152-2
By:
- Mensink, M.;
- Blaak, E. E.;
- Vidal, H.;
- de Bruin, T. W. A.;
- Glatz, J. F. C.;
- Saris, W. H. M.
Publication type:
Article
Increase in skeletal muscle fatty acid binding protein (FABPC) content is directly related to weight loss and to changes in fat oxidation following a very low calorie diet.
Published in:
Diabetologia, 2001, v. 44, n. 11, p. 2013, doi. 10.1007/s001250100005
By:
- Blaak, E. E.;
- Glatz, J. F. C.;
- M Saris, W. H.
Publication type:
Article
The effect of weight reduction on skeletal muscle UCP2 and UCP3 mRNA expression and UCP3 protein content in Type II diabetic subjects.
Published in:
Diabetologia, 2000, v. 43, n. 11, p. 1408, doi. 10.1007/s001250051547
By:
- Schrauwen, P.;
- Schaart, G.;
- Saris, W. H. M.;
- Slieker, L. J.;
- Glatz, J. F. C.;
- Vidal, H.;
- Blaak, E. E.
Publication type:
Article
Butyrate to combat obesity and obesity‐associated metabolic disorders: Current status and future implications for therapeutic use.
Published in:
Obesity Reviews, 2022, v. 23, n. 10, p. 1, doi. 10.1111/obr.13498
By:
- van Deuren, Thirza;
- Blaak, Ellen E.;
- Canfora, Emanuel E.
Publication type:
Article
Nutritional strategies to attenuate postprandial glycemic response.
Published in:
Obesity Reviews, 2022, v. 23, n. 9, p. 1, doi. 10.1111/obr.13486
By:
- Pasmans, Kenneth;
- Meex, Ruth C. R.;
- van Loon, Luc J. C.;
- Blaak, Ellen E.
Publication type:
Article
Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes.
Published in:
Obesity Reviews, 2019, v. 20, n. 9, p. 1205, doi. 10.1111/obr.12862
By:
- Meex, Ruth C.R.;
- Blaak, Ellen E.;
- Loon, Luc J.C.
Publication type:
Article
Natriuretic peptides in the control of lipid metabolism and insulin sensitivity.
Published in:
Obesity Reviews, 2017, v. 18, n. 11, p. 1243, doi. 10.1111/obr.12598
By:
- Verboven, K.;
- Hansen, D.;
- Jocken, J. W. E.;
- Blaak, E. E.
Publication type:
Article
Targeting fatty acid metabolism to improve glucose metabolism.
Published in:
Obesity Reviews, 2015, v. 16, n. 9, p. 715, doi. 10.1111/obr.12298
By:
- Stinkens, R.;
- Goossens, G. H.;
- Jocken, J. W. E.;
- Blaak, E. E.
Publication type:
Article
Impact of postprandial glycaemia on health and prevention of disease.
Published in:
Obesity Reviews, 2012, v. 13, n. 10, p. 923, doi. 10.1111/j.1467-789X.2012.01011.x
By:
- Blaak, E. E.;
- Antoine, J.-M.;
- Benton, D.;
- Björck, I.;
- Bozzetto, L.;
- Brouns, F.;
- Diamant, M.;
- Dye, L.;
- Hulshof, T.;
- Holst, J. J.;
- Lamport, D. J.;
- Laville, M.;
- Lawton, C. L.;
- Meheust, A.;
- Nilson, A.;
- Normand, S.;
- Rivellese, A. A.;
- Theis, S.;
- Torekov, S. S.;
- Vinoy, S.
Publication type:
Article
Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes?
Published in:
Obesity Reviews, 2011, v. 12, n. 4, p. 272, doi. 10.1111/j.1467-789X.2010.00797.x
By:
- Diamant, M.;
- Blaak, E. E.;
- de Vos, W. M.
Publication type:
Article
Metabolic flexibility in the development of insulin resistance and type 2 diabetes: effects of lifestyle.
Published in:
Obesity Reviews, 2009, v. 10, n. 2, p. 178, doi. 10.1111/j.1467-789X.2008.00544.x
By:
- Corpeleijn, E.;
- Saris, W. H. M.;
- Blaak, E. E.
Publication type:
Article
Possible involvement of the adipose tissue renin-angiotensin system in the pathophysiology of obesity and obesity-related disorders.
Published in:
Obesity Reviews, 2003, v. 4, n. 1, p. 43, doi. 10.1046/j.1467-789X.2003.00091.x
By:
- Goossens, G. H.;
- Blaak, E. E.;
- van Baak, M. A.
Publication type:
Article
Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27246-z
By:
- Rimbach, Rebecca;
- Yamada, Yosuke;
- Sagayama, Hiroyuki;
- Ainslie, Philip N.;
- Anderson, Lene F.;
- Anderson, Liam J.;
- Arab, Lenore;
- Baddou, Issaad;
- Bedu-Addo, Kweku;
- Blaak, Ellen E.;
- Blanc, Stephane;
- Bonomi, Alberto G.;
- Bouten, Carlijn V. C.;
- Bovet, Pascal;
- Buchowski, Maciej S.;
- Butte, Nancy F.;
- Camps, Stefan G. J. A.;
- Close, Graeme L.;
- Cooper, Jamie A.;
- Das, Sai Krupa
Publication type:
Article
Current metabolic perspective on malnutrition in obesity: towards more subgroup-based nutritional approaches?
Published in:
2020
By:
- Blaak, Ellen E.
Publication type:
journal article
Differential Mitochondrial Gene Expression in Adipose Tissue Following Weight Loss Induced by Diet or Bariatric Surgery.
Published in:
2021
By:
- van der Kolk, Birgitta W.;
- Muniandy, Maheswary;
- Kaminska, Dorota;
- Alvarez, Marcus;
- Ko, Arthur;
- Miao, Zong;
- Valsesia, Armand;
- Langin, Dominique;
- Vaittinen, Maija;
- Pääkkönen, Mirva;
- Jokinen, Riikka;
- Kaye, Sanna;
- Heinonen, Sini;
- Virtanen, Kirsi A.;
- Andersson, Daniel P.;
- Männistö, Ville;
- Saris, Wim H.;
- Astrup, Arne;
- Rydén, Mikael;
- Blaak, Ellen E.
Publication type:
journal article
Susceptibility of Human Plasma N-glycome to Low-Calorie and Different Weight-Maintenance Diets.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15772, doi. 10.3390/ijms232415772
By:
- Deriš, Helena;
- Tominac, Petra;
- Vučković, Frano;
- Astrup, Arne;
- Blaak, Ellen E.;
- Lauc, Gordan;
- Gudelj, Ivan
Publication type:
Article
Lifestyle intervention for prevention of diabetes: determinants of success for future implementation.
Published in:
Nutrition Reviews, 2009, v. 67, n. 3, p. 132, doi. 10.1111/j.1753-4887.2009.00181.x
By:
- Roumen, Cheryl;
- Blaak, Ellen E.;
- Corpeleijn, Eva
Publication type:
Article
Angiotensin II: a major regulator of subcutaneous adipose tissue blood flow in humans.
Published in:
Journal of Physiology, 2006, v. 571, n. 2, p. 451, doi. 10.1113/jphysiol.2005.101352
By:
- Goossens, G. H.;
- McQuaid, S. E.;
- Dennis, A. L.;
- Van Baak, M. A.;
- Blaak, E. E.;
- Frayn, K. N.;
- Saris, W. H. M.;
- Karpe, F.
Publication type:
Article
Vitamin D release across abdominal adipose tissue in lean and obese men: The effect of ß‐adrenergic stimulation.
Published in:
Physiological Reports, 2019, v. 7, n. 24, p. N.PAG, doi. 10.14814/phy2.14308
By:
- Pramono, Adriyan;
- Jocken, Johan W. E.;
- Goossens, Gijs H.;
- Blaak, Ellen E.
Publication type:
Article
Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women.
Published in:
2017
By:
- Most, J;
- Penders, J;
- Lucchesi, M;
- Goossens, G H;
- Blaak, E E
Publication type:
journal article
Predictors of lifestyle intervention outcome and dropout: the SLIM study.
Published in:
European Journal of Clinical Nutrition, 2011, v. 65, n. 10, p. 1141, doi. 10.1038/ejcn.2011.74
By:
- Roumen, C;
- Feskens, E J M;
- Corpeleijn, E;
- Mensink, M;
- Saris, W H M;
- Blaak, E E
Publication type:
Article
Short-term β-adrenergic regulation of leptin, adiponectin and interleukin-6 secretion in vivo in lean and obese subjects.
Published in:
Diabetes, Obesity & Metabolism, 2008, v. 10, n. 11, p. 1029, doi. 10.1111/j.1463-1326.2008.00856.x
By:
- Goossens, G. H.;
- Jocken, J. W. E.;
- van Baak, M. A.;
- Jansen, E. H. J. M.;
- Saris, W. H. M.;
- Blaak, E. E.
Publication type:
Article
Skeletal muscle uncoupling protein-3 restores upon intervention in the prediabetic and diabetic state: implications for diabetes pathogenesis?
Published in:
2007
By:
- Mensink, M.;
- Hesselink, M. K. C.;
- Borghouts, L. B.;
- Keizer, H.;
- Moonen-Kornips, E.;
- Schaart, G.;
- Blaak, E. E.;
- Schrauwen, P.
Publication type:
Letter
Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27246-z
By:
- Rimbach, Rebecca;
- Yamada, Yosuke;
- Sagayama, Hiroyuki;
- Ainslie, Philip N.;
- Anderson, Lene F.;
- Anderson, Liam J.;
- Arab, Lenore;
- Baddou, Issaad;
- Bedu-Addo, Kweku;
- Blaak, Ellen E.;
- Blanc, Stephane;
- Bonomi, Alberto G.;
- Bouten, Carlijn V. C.;
- Bovet, Pascal;
- Buchowski, Maciej S.;
- Butte, Nancy F.;
- Camps, Stefan G. J. A.;
- Close, Graeme L.;
- Cooper, Jamie A.;
- Das, Sai Krupa
Publication type:
Article
Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study.
Published in:
PLoS ONE, 2023, v. 18, n. 7, p. 1, doi. 10.1371/journal.pone.0285820
By:
- Erdős, Balázs;
- van Sloun, Bart;
- Goossens, Gijs H.;
- O'Donovan, Shauna D.;
- de Galan, Bastiaan E.;
- van Greevenbroek, Marleen M. J.;
- Stehouwer, Coen D. A.;
- Schram, Miranda T.;
- Blaak, Ellen E.;
- Adriaens, Michiel E.;
- van Riel, Natal A. W.;
- Arts, Ilja C. W.
Publication type:
Article
Angiopoietin-Like Protein 4 and Postprandial Skeletal Muscle Lipid Metabolism in Overweight and Obese Prediabetics.
Published in:
2016
By:
- van der Kolk, Birgitta W;
- Goossens, Gijs H;
- Jocken, Johan W;
- Kersten, Sander;
- Blaak, Ellen E
Publication type:
journal article
The effects of long-term valsartan treatment on skeletal muscle Fatty Acid handling in humans with impaired glucose metabolism.
Published in:
2013
By:
- Moors, Chantalle C M;
- Blaak, Ellen E;
- van der Zijl, Nynke J;
- Diamant, Michaela;
- Goossens, Gijs H
Publication type:
Journal Article
Ectopic Fat Storage in the Pancreas, Liver, and Abdominal Fat Depots: Impact on β-Cell Function in Individuals with Impaired Glucose Metabolism.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2011, v. 96, n. 2, p. 459, doi. 10.1210/jc.2010-1722
By:
- van der Zijl, N. J.;
- Goossens, G. H.;
- Moors, C. C. M.;
- van Raalte, D. H.;
- Muskiet, M. H. A.;
- Pouwels, P. J. W.;
- Blaak, E. E.;
- Diamant, M.
Publication type:
Article
Skeletal Muscle Lipase Content and Activity in Obesity and Type 2 Diabetes.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2010, v. 95, n. 12, p. 5449, doi. 10.1210/jc.2010-0776
By:
- Jocken, Johan W. E.;
- Moro, Cedric;
- Goossens, Gijs H.;
- Hansen, Dominique;
- Mairal, Aline;
- Hesselink, Matthijs K. C.;
- Langin, Dominique;
- van Loon, Luc J. C.;
- Blaak, Ellen E.
Publication type:
Article
Body composition and body fat distribution in tissue-specific insulin resistance and in response to a 12-week isocaloric dietary macronutrient intervention.
Published in:
Nutrition & Metabolism, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12986-024-00795-y
By:
- Trouwborst, Inez;
- Jardon, Kelly M.;
- Gijbels, Anouk;
- Hul, Gabby;
- Feskens, Edith J.M.;
- Afman, Lydia A.;
- Linge, Jennifer;
- Goossens, Gijs H.;
- Blaak, Ellen E.
Publication type:
Article
Dietary protein and the glycemic index handle insulin resistance within a nutritional program for avoiding weight regain after energy-restricted induced weight loss.
Published in:
Nutrition & Metabolism, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12986-022-00707-y
By:
- Vidal-Ostos, Fernando;
- Ramos-Lopez, Omar;
- Jebb, Susan A.;
- Papadaki, Angeliki;
- Pfeiffer, Andreas F. H.;
- Handjieva-Darlenska, Teodora;
- Kunešová, Marie;
- Blaak, Ellen E.;
- Astrup, Arne;
- Martinez, J. Alfredo
Publication type:
Article
Hepatic insulin resistance and muscle insulin resistance are characterized by distinct postprandial plasma metabolite profiles: a cross-sectional study.
Published in:
Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02188-0
By:
- Gijbels, Anouk;
- Erdős, Balázs;
- Trouwborst, Inez;
- Jardon, Kelly M.;
- Adriaens, Michiel E.;
- Goossens, Gijs H.;
- Blaak, Ellen E.;
- Feskens, Edith J. M.;
- Afman, Lydia A.
Publication type:
Article
Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans.
Published in:
Diabetologia, 2020, v. 63, n. 2, p. 374, doi. 10.1007/s00125-019-05025-2
By:
- Ding, Lingling;
- Goossens, Gijs H.;
- Oligschlaeger, Yvonne;
- Houben, Tom;
- Blaak, Ellen E.;
- Shiri-Sverdlov, Ronit
Publication type:
Article
Metabolic phenotyping in people living with obesity: Implications for dietary prevention.
Published in:
Reviews in Endocrine & Metabolic Disorders, 2023, v. 24, n. 5, p. 825, doi. 10.1007/s11154-023-09830-4
By:
- Blaak, Ellen E.;
- Goossens, Gijs H.
Publication type:
Article
Circulating classical monocytes are associated with CD11c<sup>+</sup> macrophages in human visceral adipose tissue.
Published in:
Scientific Reports, 2017, p. 42665, doi. 10.1038/srep42665
By:
- Wouters, Kristiaan;
- Gaens, Katrien;
- Bijnen, Mitchell;
- Verboven, Kenneth;
- Jocken, Johan;
- Wetzels, Suzan;
- Wijnands, Erwin;
- Hansen, Dominique;
- van Greevenbroek, Marleen;
- Duijvestijn, Adriaan;
- Biessen, Erik A. L.;
- Blaak, Ellen E.;
- Stehouwer, Coen D. A.;
- Schalkwijk, Casper G.
Publication type:
Article
A 3-day EGCG-supplementation reduces interstitial lactate concentration in skeletal muscle of overweight subjects.
Published in:
Scientific Reports, 2015, p. 17896, doi. 10.1038/srep17896
By:
- Most, Jasper;
- van Can, Judith G P;
- van Dijk, Jan-Willem;
- Goossens, Gijs H.;
- Jocken, Johan;
- Hospers, Jeannette J.;
- Bendik, Igor;
- Blaak, Ellen E.
Publication type:
Article
Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects.
Published in:
Diabetic Medicine, 2013, v. 30, n. 10, p. 1214, doi. 10.1111/dme.12231
By:
- Knop, F. K.;
- Konings, E.;
- Timmers, S.;
- Schrauwen, P.;
- Holst, J. J.;
- Blaak, E. E.
Publication type:
Article
Changes in transferrin are related to changes in insulin resistance: the SLIM study.
Published in:
Diabetic Medicine, 2008, v. 25, n. 12, p. 1478, doi. 10.1111/j.1464-5491.2008.02589.x
By:
- Roumen, C.;
- Feskens, E. J. M.;
- Jansen, E. H. J. M.;
- Saris, W. H. M.;
- Blaak, E. E.
Publication type:
Article

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