Works by Bjarnsholt, Thomas

Results: 120

Reflections on EWMA 2025: the limits of certainty, the elephant in the room.

Published in:

Journal of Wound Management, 2025, v. 26, n. 2, p. 136, doi. 10.35279/jowm2025.26.02.08

By:

</strong>, <strong>Author(s);
Bjarnsholt, Thomas;
tbjarnsholt@sund.ku.dk, Email

Publication type:

Article

Microbial biofilms and chronic wounds: facts and speculation.

Published in:

Journal of Wound Management, 2025, v. 26, n. 1, p. 1, doi. 10.35279/jowm2025.26.01.09

By:

</strong>, <strong>Author(s);
Jakobsen, Tim Holm;
Rumbaugh, Kendra;
Coenye, Tom;
Bjarnsholt, Thomas

Publication type:

Article

OP047 NOVEL SAMPLING AND CULTIVATION METHOD MAINTAINING 2D ORGANIZATION OF MICROBES IN CHRONIC WOUNDS.

Published in:

Journal of Wound Management, 2023, v. 24, n. 2, p. 409

By:

Iversen, Anne Kristine;
Hansen, Mads;
Fritz, Blaine;
Kirketerp-Møller, Klaus;
Jakobsen, Tim Holm;
Bjarnsholt, Thomas;
Lichtenberg, Mads

Publication type:

Article

EP366 A FIRST-IN-HUMAN CLINICAL STUDY INVESTIGATING THE SAFETY AND ANTIMICROBIAL EFFICACY OF STABILIZED HYPOCHLOROUS ACID IN PATIENTS WITH CHRONIC LEG ULCERS.

Published in:

Journal of Wound Management, 2023, v. 24, n. 2, p. 236

By:

Kirketerp-Møller, Klaus;
Robertson, Julia;
Gundersen, Glenn;
Bjarnsholt, Thomas;
Fazli, Magnus Mustafa

Publication type:

Article

EP339 MODELLING OF INTERKINGDOM SPECIES-SPECIES INTERACTIONS IN A CHRONIC WOUND MODEL TO ASSESS ANTIBIOTIC TOLERANCE.

Published in:

Journal of Wound Management, 2023, v. 24, n. 2, p. 221

By:

Sørensen, Stine;
Kvich, Lasse;
Bjarnsholt, Thomas;
Thaarup, Ida Clement

Publication type:

Article

Antimicrobials and Non-Healing Wounds. Evidence, controversies and suggestions—key messages.

Published in:

Journal of Wound Care, 2014, v. 23, n. 10, p. 477, doi. 10.12968/jowc.2014.23.10.477

By:

Gottrup, Finn;
Apelqvist, Jan;
Bjarnsholt, Thomas;
Cooper, Rose;
Moore, Zena;
Peters, Edgar J. G.;
Probst, Sebastian

Publication type:

Article

Predictive metagenomic analysis identifies specific bacterial metabolic pathways in hidradenitis suppurativa tunnels.

Published in:

Journal of the European Academy of Dermatology & Venereology, 2024, v. 38, n. 1, p. e63, doi. 10.1111/jdv.19433

By:

Ring, Hans Christian;
Thorsen, Jonathan;
Lilje, Berit;
Bay, Lene;
Bjarnsholt, Thomas;
Fuursted, Kurt;
Saunte, Ditte Marie;
Jemec, Gregor Borut;
Thomsen, Simon Francis

Publication type:

Article

Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response.

Published in:

Journal of Orthopaedic Research, 2017, v. 35, n. 10, p. 2211, doi. 10.1002/jor.23505

By:

Jensen, Louise Kruse;
Koch, Janne;
Dich‐Jorgensen, Kirstine;
Aalbæk, Bent;
Petersen, Andreas;
Fuursted, Kurt;
Bjarnsholt, Thomas;
Kragh, Kasper Nørskov;
Tøtterup, Mikkel;
Bue, Mats;
Hanberg, Pelle;
Søballe, Kjeld;
Heegaard, Peter M.H.;
Jensen, Henrik Elvang

Publication type:

Article

Oxygen Restriction Generates Difficult-to-Culture P. aeruginosa.

Published in:

Frontiers in Microbiology, 2019, p. 1, doi. 10.3389/fmicb.2019.01992

By:

Kvich, Lasse;
Fritz, Blaine;
Crone, Stephanie;
Kragh, Kasper N.;
Kolpen, Mette;
Sønderholm, Majken;
Andersson, Mikael;
Koch, Anders;
Jensen, Peter Ø.;
Bjarnsholt, Thomas

Publication type:

Article

Copper-Silver Alloy Coated Door Handles as a Potential Antibacterial Strategy in Clinical Settings.

Published in:

Coatings (2079-6412), 2020, v. 10, n. 8, p. 790, doi. 10.3390/coatings10080790

By:

Ciacotich, Nicole;
Kvich, Lasse;
Sanford, Nicholas;
Wolcott, Joseph;
Bjarnsholt, Thomas;
Gram, Lone

Publication type:

Article

Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable In Situ-Forming Depot Antibiotics Delivery System.

Published in:

Journal of Infectious Diseases, 2024, v. 230, n. 3, p. 614, doi. 10.1093/infdis/jiae139

By:

Fuglsang-Madsen, Albert Juan;
Henriksen, Nicole Lind;
Chávez, Elizabeth Serrano;
Kvich, Lasse Andersson;
Birch, Julie Knippel Melsted;
Hartmann, Katrine Top;
Eriksen, Thomas;
Bjarnsholt, Thomas;
Gottlieb, Hans;
Andresen, Thomas Lars;
Jensen, Louise Kruse;
Henriksen, Jonas Rosager;
Hansen, Anders Elias

Publication type:

Article

Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

Published in:

European Archives of Oto-Rhino-Laryngology, 2017, v. 274, n. 7, p. 2741, doi. 10.1007/s00405-017-4586-8

By:

Jensen, Ramon;
Johansen, Helle;
Bjarnsholt, Thomas;
Eickhardt-Sørensen, Steffen;
Homøe, Preben

Publication type:

Article

Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

Published in:

European Archives of Oto-Rhino-Laryngology, 2015, v. 272, n. 9, p. 2291, doi. 10.1007/s00405-014-3322-x

By:

Aanaes, Kasper;
Eickhardt, Steffen;
Johansen, Helle;
Buchwald, Christian;
Skov, Marianne;
Høiby, Niels;
Bjarnsholt, Thomas

Publication type:

Article

Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients.

Published in:

European Archives of Oto-Rhino-Laryngology, 2015, v. 272, n. 5, p. 1079, doi. 10.1007/s00405-014-2886-9

By:

Wessman, Marcus;
Bjarnsholt, Thomas;
Eickhardt-Sørensen, Steffen;
Johansen, Helle;
Homøe, Preben

Publication type:

Article

Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media.

Published in:

European Archives of Oto-Rhino-Laryngology, 2009, v. 266, n. 10, p. 1533, doi. 10.1007/s00405-009-0940-9

By:

Homøe, Preben;
Bjarnsholt, Thomas;
Wessman, Marcus;
Sørensen, Hans Christian Florian;
Johansen, Helle Krogh

Publication type:

Article

Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2009, v. 64, n. 6, p. 1241, doi. 10.1093/jac/dkp352

By:

Van Gennip, Maria;
Moser, Claus;
Christensen, Louise D.;
Bjarnsholt, Thomas;
Calum, Henrik;
Jensen, Peter Ø.;
Christophersen, Lars;
Hougen, Hans Petter;
Ciofu, Oana;
Molin, Søren;
Givskov, Michael;
Høiby, Niels

Publication type:

Article

In Situ Monitoring of the Antibacterial Activity of a Copper–Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors.

Published in:

Global Challenges, 2019, v. 3, n. 11, p. N.PAG, doi. 10.1002/gch2.201900044

By:

Ciacotich, Nicole;
Kragh, Kasper Nørskov;
Lichtenberg, Mads;
Tesdorpf, Jens Edward;
Bjarnsholt, Thomas;
Gram, Lone

Publication type:

Article

Delayed Bacterial Neutrophil Recruitment and Bacterial Bone Dispersion: New Identified Factors in Peri‐Prosthetic Joint Infection Development. Insights From an Adult Minipig Model.

Published in:

APMIS, 2025, v. 133, n. 6, p. 1, doi. 10.1111/apm.70031

By:

Hartmann, Katrine Top;
Peterlin, Anton Alexander Nolte;
Hansen, Marie Høy;
Birch, Julie Knippel Melsted;
Odgaard, Anders;
Aalbæk, Bent;
Christensen, Mads Holm;
Thaarup, Ida;
Bjarnsholt, Thomas;
de Mesy Bentley, Karen L.;
Petersen, Andreas;
Jensen, Henrik Elvang;
Jensen, Louise Kruse

Publication type:

Article

Editorial for PMI Journal 100‐Years Anniversary Focus Issue.

Published in:

APMIS, 2025, v. 133, n. 4, p. 1, doi. 10.1111/apm.70019

By:

Jensen, Peter Østrup;
Gheorghe, Alexandre Gabriella;
Bjarnsholt, Thomas

Publication type:

Article

Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection.

Published in:

APMIS, 2024, v. 132, n. 12, p. 1078, doi. 10.1111/apm.13381

By:

Jensen, Peter Østrup;
Olsen, Pernille;
Dungu, Arnold Matovu;
Egelund, Gertrud Baunbæk;
Jensen, Andreas Vestergaard;
Ravn, Pernille;
Lindegaard, Birgitte;
Hertz, Frederik Boëtius;
Bjarnsholt, Thomas;
Faurholt‐Jepsen, Daniel;
Kolpen, Mette

Publication type:

Article

Single cells and bacterial biofilm populations in chronic wound infections.

Published in:

APMIS, 2024, v. 132, n. 12, p. 1071, doi. 10.1111/apm.13344

By:

Lichtenberg, Mads;
Kirketerp‐Møller, Klaus;
Kvich, Lasse A.;
Christensen, Mads Holm;
Fritz, Blaine;
Jakobsen, Tim Holm;
Bjarnsholt, Thomas

Publication type:

Article

Antimicrobial susceptibility testing of bone and joint pathogens using isothermal microcalorimetry.

Published in:

APMIS, 2024, v. 132, n. 11, p. 814, doi. 10.1111/apm.13470

By:

Christensen, Mads H.;
Jakobsen, Tim H.;
Lichtenberg, Mads;
Hertz, Frederik B.;
Dahl, Benny;
Bjarnsholt, Thomas

Publication type:

Article

Novel sampling technique maintaining the two‐dimensional organization of microbes during cultivation from chronic wounds: The Imprint method.

Published in:

APMIS, 2024, v. 132, n. 3, p. 210, doi. 10.1111/apm.13372

By:

Iversen, Anne Kristine Servais;
Fritz, Blaine Gabriel;
Hansen, Mads Joachim;
Kirketerp‐Møller, Klaus;
Jakobsen, Tim Holm;
Bjarnsholt, Thomas;
Lichtenberg, Mads

Publication type:

Article

Centennial celebrations of the Danish Pasteur Society.

Published in:

APMIS, 2024, v. 132, n. 1, p. 3, doi. 10.1111/apm.13368

By:

Høiby, Niels;
Bjarnsholt, Thomas

Publication type:

Article

E‐cadherin and aquaporin‐3 are downregulated in wound edges of human chronic wounds.

Published in:

APMIS, 2023, v. 131, n. 8, p. 403, doi. 10.1111/apm.13332

By:

Ernstsen, Christina V.;
Riishede, Andreas;
Iversen, Anne Kristine S.;
Bay, Lene;
Bjarnsholt, Thomas;
Nejsum, Lene N.

Publication type:

Article

APMIS 2022 focus issue on human microbiome in disease and pathology.

Published in:

APMIS, 2022, v. 130, n. 12, p. 689, doi. 10.1111/apm.13283

By:

Bjarnsholt, Thomas;
Ralfkiaer, Ulrik;
Malone, Matthew

Publication type:

Article

Transcriptomic fingerprint of bacterial infection in lower extremity ulcers.

Published in:

APMIS, 2022, v. 130, n. 8, p. 524, doi. 10.1111/apm.13234

By:

Fritz, Blaine G.;
Kirkegaard, Julius B.;
Nielsen, Claus Henrik;
Kirketerp‐Møller, Klaus;
Malone, Matthew;
Bjarnsholt, Thomas

Publication type:

Article

Injection site microflora in persons with diabetes: why needle reuse is not associated with increased infections?

Published in:

APMIS, 2022, v. 130, n. 7, p. 404, doi. 10.1111/apm.13230

By:

Wareham‐Mathiassen, Sofia;
Bay, Lene;
Glenting, Vera Pinto;
Fatima, Naireen;
Bengtsson, Henrik;
Bjarnsholt, Thomas

Publication type:

Article

The gut microbiota can orchestrate the signaling pathways in colorectal cancer.

Published in:

APMIS, 2022, v. 130, n. 3, p. 121, doi. 10.1111/apm.13206

By:

Bennedsen, Astrid L. B.;
Furbo, Sara;
Bjarnsholt, Thomas;
Raskov, Hans;
Gögenur, Ismail;
Kvich, Lasse

Publication type:

Article

Dynamics of skin microbiota in shoulder surgery infections.

Published in:

APMIS, 2021, v. 129, n. 12, p. 665, doi. 10.1111/apm.13185

By:

Fatima, Naireen;
Bjarnsholt, Thomas;
Bay, Lene

Publication type:

Article

The impact of mental models on the treatment and research of chronic infections due to biofilms.

Published in:

APMIS, 2021, v. 129, n. 10, p. 598, doi. 10.1111/apm.13163

By:

Bjarnsholt, Thomas;
Mastroianni, Enrico;
Kirketerp‐Møller, Klaus;
Stewart, Philip S.;
Mähr, Aline Meret;
Domínguez Cabañes, Alonso;
Nørager, Rune

Publication type:

Article

APMIS pandemic editorial.

Published in:

APMIS, 2021, v. 129, n. 7, p. 319, doi. 10.1111/apm.13127

By:

Bjarnsholt, Thomas;
Calum, Henrik

Publication type:

Article

The discovery of bacterial biofilm in patients with muscle invasive bladder cancer.

Published in:

APMIS, 2021, v. 129, n. 5, p. 265, doi. 10.1111/apm.13097

By:

Nadler, Naomi;
Kvich, Lasse;
Bjarnsholt, Thomas;
Jensen, Jørgen Bjerggaard;
Gögenur, Ismail;
Azawi, Nessn

Publication type:

Article

Early IL‐2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN‐dominating response and reduced lung pathology.

Published in:

APMIS, 2020, v. 128, n. 12, p. 647, doi. 10.1111/apm.13072

By:

Calum, Henrik Pierre;
Moser, Claus;
Jensen, Peter Ostrup;
Bjarnsholt, Thomas;
Givskov, Michael;
Høiby, Niels

Publication type:

Article

In memoriam Elisabeth Ralfkiær 30.10.1950–11.07.2020.

Published in:

APMIS, 2020, v. 128, n. 10, p. 541, doi. 10.1111/apm.13077

By:

Jensen, Louise Kruse;
Bjarnsholt, Thomas;
Jensen, Peter Østrup;
Norrild, Bodil

Publication type:

Article

Eradication of biofilms on tympanostomy tubes with acetic acid treatment: an in vitro study.

Published in:

APMIS, 2020, v. 128, n. 6, p. 445, doi. 10.1111/apm.13044

By:

Kjeldsen, Mathilde;
Homøe, Preben;
Kirstine Nielsen, Anne;
Crone, Stephanie;
Nørskov Kragh, Kasper;
Bjarnsholt, Thomas

Publication type:

Article

The environmental occurrence of Pseudomonas aeruginosa.

Published in:

APMIS, 2020, v. 128, n. 3, p. 220, doi. 10.1111/apm.13010

By:

Crone, Stephanie;
Vives‐Flórez, Martha;
Kvich, Lasse;
Saunders, Aaron M.;
Malone, Matthew;
Nicolaisen, Mette H.;
Martínez‐García, Esteban;
Rojas‐Acosta, Catalina;
Catalina Gomez‐Puerto, Maria;
Calum, Henrik;
Whiteley, Marvin;
Kolter, Roberto;
Bjarnsholt, Thomas

Publication type:

Article

Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy.

Published in:

APMIS, 2019, v. 127, n. 10, p. 660, doi. 10.1111/apm.12986

By:

Malone, Matthew;
Fritz, Blaine G.;
Vickery, Karen;
Schwarzer, Saskia;
Sharma, Varun;
Biggs, Nathan;
Radzieta, Michael;
Jeffries, Thomas T.;
Dickson, Hugh G.;
Jensen, Slade O.;
Bjarnsholt, Thomas

Publication type:

Article

Implants induce a new niche for microbiomes.

Published in:

APMIS, 2018, v. 126, n. 8, p. 685, doi. 10.1111/apm.12862

By:

Jakobsen, Tim H.;
Eickhardt, Steffen R.;
Sønderholm, Majken;
Stavnsberg, Camilla;
Jensen, Peter Ø.;
Bjarnsholt, Thomas;
Gheorghe, Alexandra G.;
Hougen, Hans Petter;
Stenqvist, Charlotte;
Hvolris, Jesper;
Moser, Claus;
Odgaard, Anders;
Whiteley, Marvin

Publication type:

Article

The use of fluorescent staining techniques for microscopic investigation of polymorphonuclear leukocytes and bacteria.

Published in:

APMIS, 2018, v. 126, n. 10, p. 779, doi. 10.1111/apm.12888

By:

Alhede, Maria;
Stavnsbjerg, Camilla;
Bjarnsholt, Thomas

Publication type:

Article

Bacterial biofilms: a possible mechanism for chronic infection in patients with lumbar disc herniation – a prospective proof‐of‐concept study using fluorescence <italic>in situ</italic> hybridization.

Published in:

APMIS, 2018, v. 126, n. 5, p. 440, doi. 10.1111/apm.12841

By:

Ohrt‐Nissen, Søren;
Fritz, Blaine G.;
Walbom, Jonas;
Kragh, Kasper N.;
Bjarnsholt, Thomas;
Dahl, Benny;
Manniche, Claus

Publication type:

Article

Diagnosis of biofilm infections in cystic fibrosis patients.

Published in:

APMIS, 2017, v. 125, n. 4, p. 339, doi. 10.1111/apm.12689

By:

Høiby, Niels;
Bjarnsholt, Thomas;
Moser, Claus;
Jensen, Peter Østrup;
Kolpen, Mette;
Qvist, Tavs;
Aanæs, Kasper;
Pressler, Tanja;
Skov, Marianne;
Ciofu, Oana

Publication type:

Article

Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir.

Published in:

APMIS, 2017, v. 125, n. 1, p. 38, doi. 10.1111/apm.12597

By:

Jensen, Louise Kruse;
Koch, Janne;
Aalbæk, Bent;
Moodley, Arshnee;
Bjarnsholt, Thomas;
Kragh, Kasper Nørskov;
Petersen, Andreas;
Jensen, Henrik Elvang

Publication type:

Article

Identification of pathogenic microorganisms directly from positive blood vials by matrix-assisted laser desorption/ionization time of flight mass spectrometry.

Published in:

APMIS, 2013, v. 121, n. 9, p. 871, doi. 10.1111/apm.12050

By:

Nonnemann, Bettina;
Tvede, Michael;
Bjarnsholt, Thomas

Publication type:

Article

The role of bacterial biofilms in chronic infections.

Published in:

APMIS, 2013, v. 121, p. 1, doi. 10.1111/apm.12099

By:

Bjarnsholt, Thomas

Publication type:

Article

A non-fatal case of invasive zygomycete ( Lichtheimia corymbifera) infection in an allogeneic haematopoietic cell transplant recipient.

Published in:

APMIS, 2013, v. 121, n. 5, p. 456, doi. 10.1111/apm.12008

By:

Eickhardt, Steffen;
Braendstrup, Peter;
Clasen‐Linde, Erik;
Jensen, Karl E.;
Alhede, Morten;
Bjarnsholt, Thomas;
Høiby, Niels;
Vindeløv, Lars;
Moser, Claus

Publication type:

Article

An in vitro model of bacterial infections in wounds and other soft tissues.

Published in:

APMIS, 2010, v. 118, n. 2, p. 156, doi. 10.1111/j.1600-0463.2009.02580.x

By:

WERTHÉN, MARIA;
HENRIKSSON, LINA;
JENSEN, PETER ØSTRUP;
STERNBERG, CLAUS;
GIVSKOV, MICHAEL;
BJARNSHOLT, THOMAS

Publication type:

Article

Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes.

Published in:

APMIS, 2009, v. 117, n. 7, p. 537, doi. 10.1111/j.1600-0463.2009.02466.x

By:

GENNIP, MARIA VAN;
CHRISTENSEN, LOUISE DAHL;
ALHEDE, MORTEN;
PHIPPS, RICHARD;
JENSEN, PETER ØSTRUP;
CHRISTOPHERSEN, LARS;
PAMP, SÜNJE JOHANNA;
MOSER, CLAUS;
MIKKELSEN, PER JENSEN;
KOH, ANDREW Y.;
TOLKER-NIELSEN, TIM;
PIER, GERALD B.;
HØIBY, NIELS;
GIVSKOV, MICHAEL;
BJARNSHOLT, THOMAS

Publication type:

Article

Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host–pathogen interactions in cystic fibrosis.

Published in:

APMIS, 2009, v. 117, n. 2, p. 95, doi. 10.1111/j.1600-0463.2008.00018.x

By:

MOSER, CLAUS;
VAN GENNIP, MARIA;
BJARNSHOLT, THOMAS;
JENSEN, PETER ØSTRUP;
LEE, BAOLERI;
HOUGEN, HANS PETTER;
CALUM, HENRIK;
CIOFU, OANA;
GIVSKOV, MICHAEL;
MOLIN, SØREN;
HØIBY, NIELS

Publication type:

Article

The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells.

Published in:

APMIS, 2008, v. 116, n. 5, p. 361, doi. 10.1111/j.1600-0463.2008.00966.x

By:

Kristiansen, Søren;
Bjarnsholt, Thomas;
Adeltoft, Dinah;
Ifversen, Peter;
Givskov, Michael

Publication type:

Article