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Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2475, doi. 10.3390/ijms24032475
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- Article
Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation.
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- Immunology & Cell Biology, 2022, v. 100, n. 7, p. 529, doi. 10.1111/imcb.12554
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- Article
Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.70207
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- Article
Biological relevance of Granzymes A and K during E. coli sepsis.
- Published in:
- Theranostics, 2021, v. 11, n. 20, p. 9873, doi. 10.7150/thno.59418
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- Article
Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.
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- Theranostics, 2021, v. 11, n. 8, p. 3781, doi. 10.7150/thno.49288
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- Article
Increased susceptibility to acoustic trauma in a mouse model of non‐syndromic sensorineural deafness, DFNB91.
- Published in:
- European Journal of Neuroscience, 2021, v. 53, n. 5, p. 1638, doi. 10.1111/ejn.15011
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- Article
Granzyme A in Chikungunya and Other Arboviral Infections.
- Published in:
- Frontiers in Immunology, 2020, v. 10, p. 1, doi. 10.3389/fimmu.2019.03083
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- Article
A transgenic zebrafish model of hepatocyte function in human Z α1-antitrypsin deficiency.
- Published in:
- Biological Chemistry, 2019, v. 400, n. 12, p. 1603, doi. 10.1515/hsz-2018-0391
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- Publication type:
- Article
A transgenic zebrafish model of hepatocyte function in human Z α1-antitrypsin deficiency.
- Published in:
- Biological Chemistry, 2019, v. 400, n. 11, p. 1603, doi. 10.1515/hsz-2018-0391
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- Publication type:
- Article
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12279-2
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- Article
Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.
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- 2017
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- Publication type:
- journal article
A pro-survival role for the intracellular granzyme B inhibitor Serpinb9 in natural killer cells during poxvirus infection.
- Published in:
- Immunology & Cell Biology, 2017, v. 95, n. 10, p. 884, doi. 10.1038/icb.2017.59
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- Article
Granzyme K-deficient mice show no evidence of impaired antiviral immunity.
- Published in:
- Immunology & Cell Biology, 2017, v. 95, n. 8, p. 676, doi. 10.1038/icb.2017.35
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- Publication type:
- Article
RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation.
- Published in:
- PLoS Pathogens, 2017, v. 13, n. 2, p. 1, doi. 10.1371/journal.ppat.1006155
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- Article
Mice Lacking Brinp2 or Brinp3, or Both, Exhibit Behaviors Consistent with Neurodevelopmental Disorders.
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- Frontiers in Behavioral Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fnbeh.2016.00196
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- Publication type:
- Article
Brinp1<sup>-/-</sup> mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.
- Published in:
- Molecular Autism, 2016, v. 7, p. 1, doi. 10.1186/s13229-016-0079-7
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- Publication type:
- Article
A Natural Genetic Variant of Granzyme B Confers Lethality to a Common Viral Infection.
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- PLoS Pathogens, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.ppat.1004526
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- Publication type:
- Article
Blessing or curse? Proteomics in granzyme research.
- Published in:
- Proteomics - Clinical Applications, 2014, v. 8, n. 5/6, p. 351, doi. 10.1002/prca.201300096
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- Article
Are all granzymes cytotoxic in vivo?
- Published in:
- Biological Chemistry, 2014, v. 395, n. 2, p. 181, doi. 10.1515/hsz-2013-0238
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- Publication type:
- Article
Maspin is not required for embryonic development or tumour suppression.
- Published in:
- Nature Communications, 2014, v. 5, n. 1, p. 3164, doi. 10.1038/ncomms4164
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- Publication type:
- Article
Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation.
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- Immunology & Cell Biology, 2012, v. 90, n. 9, p. 841, doi. 10.1038/icb.2012.29
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- Publication type:
- Article
Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation.
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- Immunology & Cell Biology, 2012, v. 90, n. 9, p. 916, doi. 10.1038/icb.2012.42
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- Publication type:
- Article
Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within Euteleostomi.
- Published in:
- BMC Evolutionary Biology, 2012, v. 12, n. 1, p. 59, doi. 10.1186/1471-2148-12-59
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- Publication type:
- Article
The structural basis for membrane binding and pore formation by lymphocyte perforin.
- Published in:
- Nature, 2010, v. 468, n. 7322, p. 447, doi. 10.1038/nature09518
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- Publication type:
- Article
Use of granzyme B-based fluorescent protein reporters to monitor granzyme distribution and granule integrity in live cells.
- Published in:
- Biological Chemistry, 2010, v. 391, n. 8, p. 999, doi. 10.1515/BC.2010.099
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- Publication type:
- Article
Endolysosomal proteases and their inhibitors in immunity.
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- 2009
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- Publication type:
- journal article
Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement.
- Published in:
- Immunology & Cell Biology, 2009, v. 87, n. 3, p. 249, doi. 10.1038/icb.2008.98
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- Publication type:
- Article
Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement.
- Published in:
- Immunology & Cell Biology, 2009, v. 87, n. 3, p. 249, doi. 10.1038/icb.2008.98
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- Publication type:
- Article
The MACPF/CDC family of pore-forming toxins.
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- Cellular Microbiology, 2008, v. 10, n. 9, p. 1765, doi. 10.1111/j.1462-5822.2008.01191.x
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- Publication type:
- Article
SerpinB6 is an Inhibitor of Kallikrein-8 in Keratinocytes.
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- Journal of Biochemistry, 2007, v. 142, n. 4, p. 435, doi. 10.1093/jb/mvm156
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- Publication type:
- Article
Mechanisms of serpin dysfunction in disease.
- Published in:
- Expert Reviews in Molecular Medicine, 2006, v. 8, n. 31, p. 1, doi. 10.1017/S1462399406000184
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- Article
The major human and mouse granzymes are structurally and functionally divergent.
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- Journal of Cell Biology, 2006, v. 175, n. 4, p. 619, doi. 10.1083/jcb.200606073
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- Publication type:
- Article
Granzyme B-Mediated Death of Pancreatic β-Cells Requires the Proapoptotic BH3-Only Molecule Bid.
- Published in:
- Diabetes, 2006, v. 55, n. 8, p. 2212, doi. 10.2337/db06-0129
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- Article
Extracellular granzymes: current perspectives.
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- Biological Chemistry, 2006, v. 387, n. 7, p. 827, doi. 10.1515/BC.2006.106
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- Publication type:
- Article
Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis.
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- Journal of Cell Biology, 2006, v. 173, n. 1, p. 133, doi. 10.1083/jcb.200510072
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- Publication type:
- Article
Modulation and Redistribution of Proteinase Inhibitor 8 (Serpinb8) during Kidney Regeneration.
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- American Journal of Nephrology, 2006, v. 26, n. 1, p. 34, doi. 10.1159/000091784
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- Publication type:
- Article
Serpins 2005 – fun between the β-sheets.
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- FEBS Journal, 2005, v. 272, n. 19, p. 4868, doi. 10.1111/j.1742-4658.2005.04927.x
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- Article
Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin α or β: Modulation by the serpin inhibitor PI‐9.
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- Journal of Cellular Biochemistry, 2005, v. 95, n. 3, p. 598, doi. 10.1002/jcb.20415
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- Publication type:
- Article
The human serpin proteinase inhibitor-9 self-associates at physiological temperatures.
- Published in:
- Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 7, p. 1859, doi. 10.1110/ps.04715304
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- Publication type:
- Article
Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death.
- Published in:
- European Journal of Immunology, 2003, v. 33, n. 12, p. 3284, doi. 10.1002/eji.200324376
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- Publication type:
- Article
A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice.
- Published in:
- Genesis: The Journal of Genetics & Development, 2003, v. 36, n. 3, p. 149, doi. 10.1002/gene.10210
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- Article
Serpins: Finely Balanced Conformational Traps .
- Published in:
- IUBMB Life, 2002, v. 54, n. 1, p. 1, doi. 10.1080/15216540213825
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- Publication type:
- Article
Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction.
- Published in:
- Molecular Human Reproduction, 2001, v. 7, n. 12, p. 1133, doi. 10.1093/molehr/7.12.1133
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- Publication type:
- Article
Sequence, Organization, Chromosomal Localization, and Alternative Splicing of the Human Serine Protease Inhibitor Gene Hurpin (PI13) Which Is Upregulated in Psoriasis.
- Published in:
- DNA & Cell Biology, 2001, v. 20, n. 3, p. 123, doi. 10.1089/104454901300068924
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- Publication type:
- Article