Works by Biersack, Bernhard

Results: 79

Preiswerte Herstellung Janus-artiger Emulgatoren in großem Maßstab durch selektive Oberflächenmodifizierung natürlicher Kaolinitplättchen.

Published in:

Angewandte Chemie, 2012, v. 124, n. 6, p. 1376, doi. 10.1002/ange.201106710

By:

Hirsemann, Dunja;
Shylesh, Sankaranarayanapillai;
De Souza, Roger A.;
Diar-Bakerly, Bashar;
Biersack, Bernhard;
Mueller, David N.;
Martin, Manfred;
Schobert, Rainer;
Breu, Josef

Publication type:

Article

Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 7, p. 1539, doi. 10.3390/v15071539

By:

Asthana, Abhishek;
Corona, Angela;
Shin, Woo-Jin;
Kwak, Mi-Jeong;
Gaughan, Christina;
Tramontano, Enzo;
Jung, Jae U.;
Schobert, Rainer;
Jha, Babal Kant;
Silverman, Robert H.;
Biersack, Bernhard

Publication type:

Article

Antitumor and antiangiogenic activity of the novel chimeric inhibitor animacroxam in testicular germ cell cancer.

Published in:

Molecular Oncology, 2019, v. 13, n. 12, p. 2679, doi. 10.1002/1878-0261.12582

By:

Steinemann, Gustav;
Dittmer, Alexandra;
Schmidt, Jacob;
Josuttis, David;
Fähling, Michael;
Biersack, Bernhard;
Beindorff, Nicola;
Jolante Koziolek, Eva;
Schobert, Rainer;
Brenner, Winfried;
Müller, Thomas;
Nitzsche, Bianca;
Höpfner, Michael

Publication type:

Article

Guided Antitumoural Drugs: (Imidazol‐2‐ylidene)(L)gold(I) Complexes Seeking Cellular Targets Controlled by the Nature of Ligand L.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 15, p. 5003, doi. 10.1002/chem.202005451

By:

Bär, Sofia I.;
Gold, Madeleine;
Schleser, Sebastian W.;
Rehm, Tobias;
Bär, Alexander;
Köhler, Leonhard;
Carnell, Lucas R.;
Biersack, Bernhard;
Schobert, Rainer

Publication type:

Article

Role and Function of Receptor Tyrosine Kinases in BRAF Mutant Cancers.

Published in:

Receptors, 2024, v. 3, n. 1, p. 58, doi. 10.3390/receptors3010005

By:

Biersack, Bernhard;
Tahtamouni, Lubna;
Höpfner, Michael

Publication type:

Article

Superior Anticancer and Antifungal Activities of New Sulfanyl-Substituted Niclosamide Derivatives.

Published in:

Biomedicines, 2024, v. 13, n. 7, p. 1621, doi. 10.3390/biomedicines12071621

By:

Ma, Jingyi;
Veeragoni, Dileepkumar;
Ghosh, Hindole;
Mutter, Nicole;
Barbosa, Gisele;
Webster, Lauren;
Schobert, Rainer;
Sande, Wendy van de;
Dandawate, Prasad;
Biersack, Bernhard

Publication type:

Article

Antiparasitic Activity of Fluorophenyl-Substituted Pyrimido[1,2- a ]benzimidazoles.

Published in:

Biomedicines, 2023, v. 11, n. 1, p. 219, doi. 10.3390/biomedicines11010219

By:

Nasr, Ibrahim S. Al;
Koko, Waleed S.;
Khan, Tariq A.;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

A New Synthetic Curcuminoid Displays Antitumor Activities in Metastasized Melanoma.

Published in:

Cells (2073-4409), 2023, v. 12, n. 22, p. 2619, doi. 10.3390/cells12222619

By:

Kaps, Leonard;
Klefenz, Adrian;
Traenckner, Henry;
Schneider, Paul;
Andronache, Ion;
Schobert, Rainer;
Biersack, Bernhard;
Schuppan, Detlef

Publication type:

Article

Fluorinated and N -Acryloyl-Modified 3,5-Di[(E)-benzylidene]piperidin-4-one Curcuminoids for the Treatment of Pancreatic Carcinoma.

Published in:

Pharmaceutics, 2023, v. 15, n. 7, p. 1921, doi. 10.3390/pharmaceutics15071921

By:

Ghosh, Hindole;
Bhattacharyya, Sangita;
Schobert, Rainer;
Dandawate, Prasad;
Biersack, Bernhard

Publication type:

Article

Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 1, p. 50, doi. 10.3390/ph18010050

By:

Viperino, Alessandra;
Höpfner, Michael;
Edel, Nicole;
Al Nasr, Ibrahim S.;
Koko, Waleed S.;
Khan, Tariq A.;
Ben Abdelmalek, Imen;
Schobert, Rainer;
Biersack, Bernhard;
Nitzsche, Bianca

Publication type:

Article

Improved Anticancer Activities of a New Pentafluorothio-Substituted Vorinostat-Type Histone Deacetylase Inhibitor.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 12, p. 1319, doi. 10.3390/ph14121319

By:

Goehringer, Nils;
Peng, Yayi;
Nitzsche, Bianca;
Biermann, Hannah;
Pradhan, Rohan;
Schobert, Rainer;
Herling, Marco;
Höpfner, Michael;
Biersack, Bernhard

Publication type:

Article

Biological evaluation of 4,5-diarylimidazoles with hydroxamic acid appendages as novel dual mode anticancer agents.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 4, p. 691, doi. 10.1007/s00280-015-2685-z

By:

Mahal, Katharina;
Schruefer, Sebastian;
Steinemann, Gustav;
Rausch, Franziska;
Schobert, Rainer;
Biersack, Bernhard;
Höpfner, Michael

Publication type:

Article

DNA as a Natural Flame Retardant for Cellulose Acetate Polymer Mixtures.

Published in:

ChemistrySelect, 2021, v. 6, n. 15, p. 3605, doi. 10.1002/slct.202004493

By:

Koedel, Justus;
Seibt, Sebastian;
Callsen, Christoph;
Puchtler, Florian;
Weise, Markus;
Weidinger, Andy;
Altstaedt, Volker;
Ruckdäschel, Holger;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

Antiparasitic and Antifungal Activities of Cetyl-Maritima, a New N -Cetyl-Modified Maritima Derivative.

Published in:

Antibiotics (2079-6382), 2025, v. 14, n. 3, p. 321, doi. 10.3390/antibiotics14030321

By:

Al Nasr, Ibrahim S.;
Ma, Jingyi;
Khan, Tariq A.;
Koko, Waleed S.;
Ben Abdelmalek, Imen;
Schobert, Rainer;
van de Sande, Wendy;
Biersack, Bernhard

Publication type:

Article

Antiparasitic Activities of Acyl Hydrazones from Cinnamaldehydes and Structurally Related Fragrances.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 12, p. 1114, doi. 10.3390/antibiotics13121114

By:

Al Nasr, Ibrahim S.;
Koko, Waleed S.;
Khan, Tariq A.;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

Chimeric HDAC and the cytoskeleton inhibitor broxbam as a novel therapeutic strategy for liver cancer.

Published in:

International Journal of Oncology, 2022, v. 60, n. 6, p. N.PAG

By:

Bär, Sofia Isolde;
Dittmer, Alexandra;
Nitzsche, Bianca;
Ter-Avetisyan, Gohar;
Fähling, Michael;
Klefenz, Adrian;
Kaps, Leonard;
Biersack, Bernhard;
Schobert, Rainer;
Höpfner, Michael

Publication type:

Article

Novel Thienyl-Based Tyrosine Kinase Inhibitors for the Treatment of Hepatocellular Carcinoma.

Published in:

Journal of Personalized Medicine, 2022, v. 12, n. 5, p. 738, doi. 10.3390/jpm12050738

By:

Ma, Andi;
Biersack, Bernhard;
Goehringer, Nils;
Nitzsche, Bianca;
Höpfner, Michael

Publication type:

Article

Large-Scale, Low-Cost Fabrication of Janus-Type Emulsifiers by Selective Decoration of Natural Kaolinite Platelets.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 6, p. 1348, doi. 10.1002/anie.201106710

By:

Hirsemann, Dunja;
Shylesh, Sankaranarayanapillai;
De Souza, Roger A.;
Diar-Bakerly, Bashar;
Biersack, Bernhard;
Mueller, David N.;
Martin, Manfred;
Schobert, Rainer;
Breu, Josef

Publication type:

Article

The Antifungal Potential of Niclosamide and Structurally Related Salicylanilides.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 5977, doi. 10.3390/ijms25115977

By:

Biersack, Bernhard

Publication type:

Article

Editorial for the Special Issue—"Recent Advances of Novel Pharmaceutical Designs for Anti-Cancer Therapies".

Published in:

2023

By:

Biersack, Bernhard

Publication type:

Editorial

New 4,5-Diarylimidazol-2-ylidene–iodidogold(I) Complexes with High Activity against Esophageal Adenocarcinoma Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5738, doi. 10.3390/ijms24065738

By:

Schleser, Sebastian W.;
Ghosh, Hindole;
Hörner, Gerald;
Seib, Jonathan;
Bhattacharyya, Sangita;
Weber, Birgit;
Schobert, Rainer;
Dandawate, Prasad;
Biersack, Bernhard

Publication type:

Article

Synthetic Small Molecule Modulators of Hsp70 and Hsp40 Chaperones as Promising Anticancer Agents.

Published in:

2023

By:

Nitzsche, Bianca;
Höpfner, Michael;
Biersack, Bernhard

Publication type:

Literature Review

Synthesis and Anticancer Evaluation of New Indole-Based Tyrphostin Derivatives and Their (p -Cymene)dichloridoruthenium(II) Complexes.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 854, doi. 10.3390/ijms24010854

By:

Oberhuber, Natalie;
Ghosh, Hindole;
Nitzsche, Bianca;
Dandawate, Prasad;
Höpfner, Michael;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

Antitumor Effects of a New Retinoate of the Fungal Cytotoxin Illudin M in Brain Tumor Models.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9056, doi. 10.3390/ijms23169056

By:

Linder, Benedikt;
Zoldakova, Miroslava;
Kornyei, Zsuzsanna;
Köhler, Leonhard H. F.;
Seibt, Sebastian;
Menger, Dominic;
Wetzel, André;
Madarász, Emília;
Schobert, Rainer;
Kögel, Donat;
Biersack, Bernhard

Publication type:

Article

Imidazole Analogs of Vascular-Disrupting Combretastatin A-4 with Pleiotropic Efficacy against Resistant Colorectal Cancer Models.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 13082, doi. 10.3390/ijms222313082

By:

Reipsch, Franziska;
Biersack, Bernhard;
Lucas, Henrike;
Schobert, Rainer;
Mueller, Thomas

Publication type:

Article

Anticancer Activity and Mechanisms of Action of New Chimeric EGFR/HDAC-Inhibitors.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8432, doi. 10.3390/ijms22168432

By:

Goehringer, Nils;
Biersack, Bernhard;
Peng, Yayi;
Schobert, Rainer;
Herling, Marco;
Ma, Andi;
Nitzsche, Bianca;
Höpfner, Michael

Publication type:

Article

New 3-Aryl-2-(2-thienyl)acrylonitriles with High Activity Against Hepatoma Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2243, doi. 10.3390/ijms22052243

By:

Schaller, Eva;
Ma, Andi;
Gosch, Lisa Chiara;
Klefenz, Adrian;
Schaller, David;
Goehringer, Nils;
Kaps, Leonard;
Schuppan, Detlef;
Volkamer, Andrea;
Schobert, Rainer;
Biersack, Bernhard;
Nitzsche, Bianca;
Höpfner, Michael;
Lee, Seok-Geun

Publication type:

Article

Garcinol Sensitizes NSCLC Cells to Standard Therapies by Regulating EMT-Modulating miRNAs.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 4, p. 800, doi. 10.3390/ijms20040800

By:

Farhan, Mohd;
Malik, Arshi;
Ullah, Mohammad Fahad;
Afaq, Sarah;
Faisal, Mohd;
Farooqi, Ammad Ahmad;
Biersack, Bernhard;
Schobert, Rainer;
Ahmad, Aamir

Publication type:

Article

Oxazole-Bridged Combretastatin A-4 Derivatives with Tethered Hydroxamic Acids: Structure–Activity Relations of New Inhibitors of HDAC and/or Tubulin Function.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 2, p. 383, doi. 10.3390/ijms20020383

By:

Schmitt, Florian;
Gosch, Lisa Chiara;
Dittmer, Alexandra;
Rothemund, Matthias;
Mueller, Thomas;
Schobert, Rainer;
Biersack, Bernhard;
Volkamer, Andrea;
Höpfner, Michael

Publication type:

Article

Synergistic "gold effects" of anti-vascular 4,5-diarylimidazol-2-ylidene gold(I) carbene complexes.

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2013, v. 51, n. 1, p. 44, doi. 10.5414/CPP51044

By:

Münzner, Julienne;
Biersack, Bernhard;
Kaps, Leonard;
Schobert, Rainer;
Sasse, Florenz

Publication type:

Article

New oxazole-bridged combretastatin A-4 analogues as potential vascular-disrupting agents.

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2013, v. 51, n. 1, p. 41, doi. 10.5414/CPP51041

By:

Mahal, Katharina;
Biersack, Bernhard;
Schobert, Rainer

Publication type:

Article

Perspectives on the Role of Isoflavones in Prostate Cancer.

Published in:

AAPS Journal, 2013, v. 15, n. 4, p. 991, doi. 10.1208/s12248-013-9507-1

By:

Ahmad, Aamir;
Biersack, Bernhard;
Li, Yiwei;
Bao, Bin;
Kong, Dejuan;
Ali, Shadan;
Banerjee, Sanjeev;
Sarkar, Fazlul

Publication type:

Article

Targeting Colon Cancer Cells with Pyrazino‐Imidazolinone Derivatives: Synthesis, Molecular Docking, and in Vitro Evaluation of Anti‐Proliferative and Pro‐Apoptotic Activities.

Published in:

Chemistry & Biodiversity, 2023, v. 20, n. 8, p. 1, doi. 10.1002/cbdv.202300149

By:

Tambat, Nazia;
Tambe, Pranav;
Shaikh, Amin;
Shiekh, Kounsar N.;
Köhler, Leonhard H. F.;
Schobert, Rainer;
Biersack, Bernhard;
Ahmed, Khursheed

Publication type:

Article

Regiospecific Reduction of 4,6‐Dinitrobenzimidazoles: Synthesis, Characterization, and Biological Evaluation.

Published in:

Chemistry & Biodiversity, 2023, v. 20, n. 7, p. 1, doi. 10.1002/cbdv.202300191

By:

Abouelhaoul, El Alami;
El Kihel, Abdellatif;
Ahbala, Mustapha;
Sdassi, Hamid;
Köhler, Leonhard H. F.;
Bauchat, Patrick;
Roisnel, Thierry;
Khan, Tariq A.;
Al Nasr, Ibrahim S.;
Koko, Waleed S.;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

Antifungal Activity of Natural Naphthoquinones and Anthraquinones against Madurella mycetomatis.

Published in:

Chemistry & Biodiversity, 2023, v. 20, n. 5, p. 1, doi. 10.1002/cbdv.202300151

By:

Jingyi Ma;
Todd, Matthew;
van de Sande, Wendy W. J.;
Biersack, Bernhard

Publication type:

Article

An Update on Natural Antileishmanial Treatment Options from Plants, Fungi and Algae.

Published in:

Chemistry & Biodiversity, 2022, v. 19, n. 1, p. 1, doi. 10.1002/cbdv.202100542

By:

Koko, Waleed S.;
Al Nasr, Ibrahim S.;
Khan, Tariq A.;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

Front Cover: Activity of Fluorinated Curcuminoids against Leishmania major and Toxoplasma gondii Parasites (Chem. Biodiversity 9/2021).

Published in:

Chemistry & Biodiversity, 2021, v. 18, n. 9, p. 1, doi. 10.1002/cbdv.202100658

By:

Khan, Tariq A.;
Koko, Waleed S.;
Al Nasr, Ibrahim S.;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

Activity of Fluorinated Curcuminoids against Leishmania major and Toxoplasma gondii Parasites.

Published in:

Chemistry & Biodiversity, 2021, v. 18, n. 9, p. 1, doi. 10.1002/cbdv.202100381

By:

Khan, Tariq A.;
Koko, Waleed S.;
Al Nasr, Ibrahim S.;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

New Pyrano‐4H‐benzo[g]chromene‐5,10‐diones with Antiparasitic and Antioxidant Activities.

Published in:

Chemistry & Biodiversity, 2021, v. 18, n. 1, p. 1, doi. 10.1002/cbdv.202000839

By:

Al Nasr, Ibrahim S.;
Jentzsch, Jana;
Shaikh, Amin;
Singh Shuveksh, Priti;
Koko, Waleed S.;
Khan, Tariq A.;
Ahmed, Khursheed;
Schobert, Rainer;
Ersfeld, Klaus;
Biersack, Bernhard

Publication type:

Article

Targeting growth of breast cancer cell line (MCF-7) with curcumin-pyrimidine analogs.

Published in:

Journal of Chemical Sciences, 2022, v. 134, n. 4, p. 1, doi. 10.1007/s12039-022-02115-4

By:

Shaikh, Siraj B;
Tambe, Pranav;
Mujahid, Yusufi;
Santra, Manas K;
Biersack, Bernhard;
Ahmed, Khursheed

Publication type:

Article

Role of JNK and NF-κB in mediating the effect of combretastatin A-4 and brimamin on endothelial and carcinoma cells.

Published in:

Cellular Oncology (2211-3428), 2015, v. 38, n. 6, p. 463, doi. 10.1007/s13402-015-0243-7

By:

Mahal, Katharina;
Ahmad, Aamir;
Sethi, Seema;
Resch, Marcus;
Ficner, Ralf;
Sarkar, Fazlul;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

End Group Dye‐Labeled Polycarbonate Block Copolymers for Micellar (Immuno‐)Drug Delivery.

Published in:

Macromolecular Rapid Communications, 2022, v. 43, n. 12, p. 1, doi. 10.1002/marc.202200095

By:

Czysch, Christian;
Medina‐Montano, Carolina;
Dal, Nils‐Jørgen Knudsen;
Dinh, Thi;
Fröder, Yannick;
Winterwerber, Pia;
Maxeiner, Konrad;
Räder, Hans‐Joachim;
Schuppan, Detlef;
Schild, Hansjörg;
Bros, Matthias;
Biersack, Bernhard;
Feranoli, Federico;
Grabbe, Stephan;
Nuhn, Lutz

Publication type:

Article

Ferrocenyl-Coupled N-Heterocyclic Carbene Complexes of Gold(I): A Successful Approach to Multinuclear Anticancer Drugs.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 52, p. 18953, doi. 10.1002/chem.201604246

By:

Muenzner, Julienne K.;
Biersack, Bernhard;
Albrecht, Alexander;
Rehm, Tobias;
Lacher, Ulrike;
Milius, Wolfgang;
Casini, Angela;
Zhang, Jing ‐ Jing;
Ott, Ingo;
Brabec, Viktor;
Stuchlikova, Olga;
Andronache, Ion C.;
Kaps, Leonard;
Schuppan, Detlef;
Schobert, Rainer

Publication type:

Article

Antitumor activity of the new tyrphostin briva against BRAF<sup>V600E</sup>-mutant colorectal carcinoma cells.

Published in:

Investigational New Drugs, 2023, v. 41, n. 6, p. 791, doi. 10.1007/s10637-023-01402-2

By:

Saleh, Khaled;
Al Sakhen, Mai;
Kanaan, Sana;
Yasin, Salem;
Höpfner, Michael;
Tahtamouni, Lubna;
Biersack, Bernhard

Publication type:

Article

3D cell cultures, as a surrogate for animal models, enhance the diagnostic value of preclinical in vitro investigations by adding information on the tumour microenvironment: a comparative study of new dual-mode HDAC inhibitors.

Published in:

Investigational New Drugs, 2022, v. 40, n. 5, p. 953, doi. 10.1007/s10637-022-01280-0

By:

Bär, Sofia I.;
Biersack, Bernhard;
Schobert, Rainer

Publication type:

Article

Combretastatin A-4 derived imidazoles show cytotoxic, antivascular, and antimetastatic effects based on cytoskeletal reorganisation.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 541, doi. 10.1007/s10637-015-0215-9

By:

Mahal, Katharina;
Biersack, Bernhard;
Caysa, Henrike;
Schobert, Rainer;
Mueller, Thomas

Publication type:

Article

4,5-Diaryl imidazoles with hydroxamic acid appendages as anti-hepatoma agents.

Published in:

Investigational New Drugs, 2015, v. 33, n. 1, p. 104, doi. 10.1007/s10637-014-0188-0

By:

Fazio, Pietro;
Lingelbach, Susanne;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

A New Pentafluorothio-Substituted Curcuminoid with Superior Antitumor Activity.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 947, doi. 10.3390/biom11070947

By:

Linder, Benedikt;
Köhler, Leonhard H. F.;
Reisbeck, Lisa;
Menger, Dominic;
Subramaniam, Dharmalingam;
Herold-Mende, Christel;
Anant, Shrikant;
Schobert, Rainer;
Biersack, Bernhard;
Kögel, Donat

Publication type:

Article

Halogenated Bis(methoxybenzylidene)‐4‐piperidone Curcuminoids with Improved Anticancer Activity.

Published in:

ChemMedChem, 2018, v. 13, n. 11, p. 1115, doi. 10.1002/cmdc.201800135

By:

Schmitt, Florian;
Subramaniam, Dharmalingam;
Anant, Shrikant;
Padhye, Subhash;
Begemann, Gerrit;
Schobert, Rainer;
Biersack, Bernhard

Publication type:

Article

Gold(I) Biscarbene Complexes Derived from Vascular-Disrupting Combretastatin A-4 Address Different Targets and Show Antimetastatic Potential.

Published in:

ChemMedChem, 2014, v. 9, n. 6, p. 1195, doi. 10.1002/cmdc.201400049

By:

Muenzner, Julienne K.;
Biersack, Bernhard;
Kalie, Hussein;
Andronache, Ion C.;
Kaps, Leonard;
Schuppan, Detlef;
Sasse, Florenz;
Schobert, Rainer

Publication type:

Article