Works by Bickle, Marc

Results: 20

Cell wall integrity modulates RHO1 activity via the exchange factor ROM2.

Published in:

EMBO Journal, 1998, v. 17, n. 8, p. 2235, doi. 10.1093/emboj/17.8.2235

By:

Bickle, Marc;
Delley, Pierre-Alain;
Schmidt, Anja;
Hall, Michael N.

Publication type:

Article

The beautiful cell: high-content screening in drug discovery.

Published in:

Analytical & Bioanalytical Chemistry, 2010, v. 398, n. 1, p. 219, doi. 10.1007/s00216-010-3788-3

By:

Bickle, Marc

Publication type:

Article

Modeling early pathophysiological phenotypes of diabetic retinopathy in a human inner blood-retinal barrier-on-a-chip.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45456-z

By:

Maurissen, Thomas L.;
Spielmann, Alena J.;
Schellenberg, Gabriella;
Bickle, Marc;
Vieira, Jose Ricardo;
Lai, Si Ying;
Pavlou, Georgios;
Fauser, Sascha;
Westenskow, Peter D.;
Kamm, Roger D.;
Ragelle, Héloïse

Publication type:

Article

Axonal Lysosomal Assays for Characterizing the Effects of LRRK2 G2019S.

Published in:

Biology (2079-7737), 2024, v. 13, n. 1, p. 58, doi. 10.3390/biology13010058

By:

Bhatia, Priyanka;
Bickle, Marc;
Agrawal, Amay A.;
Truss, Buster;
Nikolaidi, Aikaterina;
Brockmann, Kathrin;
Reinhardt, Lydia;
Vogel, Stefanie;
Szegoe, Eva M.;
Pal, Arun;
Hermann, Andreas;
Mikicic, Ivan;
Yun, Maximina;
Falkenburger, Björn;
Sterneckert, Jared

Publication type:

Article

Identification of siRNA delivery enhancers by a chemical library screen.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 16, p. 7984, doi. 10.1093/nar/gkv762

By:

Gilleron, Jerome;
Paramasivam, Prasath;
Zeigerer, Anja;
Querbes, William;
Marsico, Giovanni;
Andree, Cordula;
Seifert, Sarah;
Amaya, Pablo;
Stöter, Martin;
Koteliansky, Victor;
Waldmann, Herbert;
Fitzgerald, Kevin;
Kalaidzidis, Yannis;
Akinc, Akin;
Maier, Martin A.;
Manoharan, Muthiah;
Bickle, Marc;
Zerial, Marino

Publication type:

Article

Phenotype loss is associated with widespread divergence of the gene regulatory landscape in evolution.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07122-z

By:

Roscito, Juliana G.;
Sameith, Katrin;
Parra, Genis;
Langer, Bjoern E.;
Petzold, Andreas;
Moebius, Claudia;
Bickle, Marc;
Rodrigues, Miguel Trefaut;
Hiller, Michael

Publication type:

Article

Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery.

Published in:

FASEB Journal, 2019, v. 33, n. 8, p. 9235, doi. 10.1096/fj.201802603RR

By:

Poser, Steven W.;
Otto, Oliver;
Arps-Forker, Carina;
Yan Ge;
Herbig, Maik;
Andree, Cordula;
Gruetzmann, Konrad;
Adasme, Melissa F.;
Stodolak, Szymon;
Nikolakopoulou, Polyxeni;
Park, Deric M.;
Mcintyre, Alan;
Lesche, Mathias;
Dahl, Andreas;
Lennig, Petra;
Bornstein, Stefan R.;
Schroeck, Evelin;
Klink, Barbara;
Leker, Ronen R.;
Bickle, Marc

Publication type:

Article

Age-dependent labeling and imaging of insulin secretory granules.

Published in:

2013

By:

Ivanova, Anna;
Kalaidzidis, Yannis;
Dirkx, Ronald;
Sarov, Mihail;
Gerlach, Michael;
Schroth-Diez, Britta;
Müller, Andreas;
Liu, Yanmei;
Andree, Cordula;
Mulligan, Bernard;
Münster, Carla;
Kurth, Thomas;
Bickle, Marc;
Speier, Stephan;
Anastassiadis, Konstantinos;
Solimena, Michele

Publication type:

journal article

Age-Dependent Labeling and Imaging of Insulin Secretory Granules.

Published in:

Diabetes, 2013, v. 62, n. 11, p. 3687, doi. 10.2337/db12-1819

By:

Ivanova, Anna;
Kalaidzidis, Yannis;
Dirkx, Ronald;
Sarov, Mihail;
Gerlach, Michael;
Schroth-Diez, Britta;
Müller, Andreas;
Yanmei Liu;
Andree, Cordula;
Mulligan, Bernard;
Münster, Carla;
Kurth, Thomas;
Bickle, Marc;
Speier, Stephan;
Anastassiadis, Konstantinos;
Solimena, Michele

Publication type:

Article

Erratum to: Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model.

Published in:

2014

By:

Borg, Danielle;
Weigelt, Marc;
Wilhelm, Carmen;
Gerlach, Michael;
Bickle, Marc;
Speier, Stephan;
Bonifacio, Ezio;
Hommel, Angela

Publication type:

Erratum

Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model.

Published in:

Diabetologia, 2014, v. 57, n. 3, p. 522, doi. 10.1007/s00125-013-3109-4

By:

Borg, Danielle;
Weigelt, Marc;
Wilhelm, Carmen;
Gerlach, Michael;
Bickle, Marc;
Speier, Stephan;
Bonifacio, Ezio;
Hommel, Angela

Publication type:

Article

Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen.

Published in:

Nature Protocols, 2014, v. 9, n. 2, p. 474, doi. 10.1038/nprot.2014.027

By:

Sundaramurthy, Varadharajan;
Barsacchi, Rico;
Chernykh, Mikhail;
Stöter, Martin;
Tomschke, Nadine;
Bickle, Marc;
Kalaidzidis, Yannis;
Zerial, Marino

Publication type:

Article

A RasGAP SH3 Peptide Aptamer Inhibits RasGAP-Aurora Interaction and Induces Caspase-Independent Tumor Cell Death.

Published in:

PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0002902

By:

Pamonsinlapatham, Perayot;
Hadj-Slimane, Réda;
Raynaud, Françoise;
Bickle, Marc;
Corneloup, Claudine;
Barthelaix, Audrey;
Lepelletier, Yves;
Mercier, Perrine;
Schapira, Matthieu;
Samson, Jérôme;
Mathieu, Anne-Laure;
Hugo, Nicolas;
Moncorgé, Olivier;
Mikaelian, Ivan;
Dufour, Sylvie;
Garbay, Christiane;
Colas, Pierre

Publication type:

Article

Viral Infections Exacerbate FUS-ALS Phenotypes in iPSC-Derived Spinal Neurons in a Virus Species-Specific Manner.

Published in:

Frontiers in Cellular Neuroscience, 2019, p. 1, doi. 10.3389/fncel.2019.00480

By:

Bellmann, Jessica;
Monette, Anne;
Tripathy, Vadreenath;
Sójka, Anna;
Abo-Rady, Masin;
Janosh, Antje;
Bhatnagar, Rajat;
Bickle, Marc;
Mouland, Andrew J.;
Sterneckert, Jared

Publication type:

Article

Unbiased Screens for Modifiers of Alpha-Synuclein Toxicity.

Published in:

Current Neurology & Neuroscience Reports, 2019, v. 19, n. 2, p. 1, doi. 10.1007/s11910-019-0925-z

By:

Höllerhage, Matthias;
Bickle, Marc;
Höglinger, Günter U.

Publication type:

Article

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation.

Published in:

Scientific Reports, 2016, p. 29868, doi. 10.1038/srep29868

By:

Carthy, Jon M.;
Stöter, Martin;
Bellomo, Claudia;
Vanlandewijck, Michael;
Heldin, Angelos;
Morén, Anita;
Kardassis, Dimitris;
Gahman, Timothy C.;
Shiau, Andrew K.;
Bickle, Marc;
Zerial, Marino;
Heldin, Carl-Henrik;
Moustakas, Aristidis

Publication type:

Article

Gender, Contraceptives and Individual Metabolic Predisposition Shape a Healthy Plasma Lipidome.

Published in:

Scientific Reports, 2016, p. 27710, doi. 10.1038/srep27710

By:

Sales, Susanne;
Graessler, Juergen;
Ciucci, Sara;
Al-Atrib, Rania;
Vihervaara, Terhi;
Schuhmann, Kai;
Kauhanen, Dimple;
Sysi-Aho, Marko;
Bornstein, Stefan R.;
Bickle, Marc;
Cannistraci, Carlo V.;
Ekroos, Kim;
Shevchenko, Andrej

Publication type:

Article

A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson's disease cell model.

Published in:

Translational Neurodegeneration, 2025, v. 14, n. 1, p. 1, doi. 10.1186/s40035-025-00486-5

By:

Höllerhage, Matthias;
Duan, Linghan;
Chua, Oscar Wing Ho;
Moebius, Claudia;
Bothe, Svenja H.;
Losse, Kristina;
Kotzur, Rebecca;
Lau, Kristina;
Hopfner, Franziska;
Richter, Franziska;
Wahl-Schott, Christian;
Bickle, Marc;
Höglinger, Günter U.

Publication type:

Article

Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape.

Published in:

Nature Biotechnology, 2013, v. 31, n. 7, p. 638, doi. 10.1038/nbt.2612

By:

Gilleron, Jerome;
Querbes, William;
Zeigerer, Anja;
Borodovsky, Anna;
Marsico, Giovanni;
Schubert, Undine;
Manygoats, Kevin;
Seifert, Sarah;
Andree, Cordula;
Stöter, Martin;
Epstein-Barash, Hila;
Zhang, Ligang;
Koteliansky, Victor;
Fitzgerald, Kevin;
Fava, Eugenio;
Bickle, Marc;
Kalaidzidis, Yannis;
Akinc, Akin;
Maier, Martin;
Zerial, Marino

Publication type:

Article

Statistical integration of multi-omics and drug screening data from cell lines.

Published in:

PLoS Computational Biology, 2024, v. 20, n. 1, p. 1, doi. 10.1371/journal.pcbi.1011809

By:

el Bouhaddani, Said;
Höllerhage, Matthias;
Uh, Hae-Won;
Moebius, Claudia;
Bickle, Marc;
Höglinger, Günter;
Houwing-Duistermaat, Jeanine

Publication type:

Article