Works by Bickford, Paula C.

Results: 46

Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion.

Published in:

Journal of Comparative Neurology, 2000, v. 427, n. 3, p. 440, doi. 10.1002/1096-9861(20001120)427:3<440::AID-CNE10>3.0.CO;2-7

By:

Zuch, Christina L.;
Nordstroem, Vivian K.;
Briedrick, Lori A.;
Hoernig, George R.;
Granholm, Ann-Charlotte;
Bickford, Paula C.

Publication type:

Article

Nutraceutical intervention reverses the negative effects of blood from aged rats on stem cells.

Published in:

Age (0161-9152), 2015, v. 37, n. 5, p. 1, doi. 10.1007/s11357-015-9840-7

By:

Bickford, Paula C.;
Kaneko, Yuji;
Grimmig, Bethany;
Pappas, Colleen;
Small, Brent;
Sanberg, Cyndy D.;
Sanberg, Paul R.;
Tan, Jun;
Douglas Shytle, R.

Publication type:

Article

Chronic alcohol exposure during young adulthood attenuates microglial reactivity and downstream immune response pathways in a mouse model of tauopathy later in life.

Published in:

Alcohol, Clinical & Experimental Research, 2025, v. 49, n. 5, p. 985, doi. 10.1111/acer.70034

By:

Wolf, Tiara;
Moss, Lauren;
Hudson, Charles;
Winters, Alexis M.;
Abdelmaboud, Salma S.;
Avlas, Marta;
Wohlfahrt, Jessica;
Guergues, Jennifer;
Bickford, Paula C.;
Stevens, Stanley M.

Publication type:

Article

Brain-Derived Neurotrophic Factor Is Required for the Establishment of the Proper Number of Dopaminergic Neurons in the Substantia Nigra Pars Compacta.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 26, p. 6251, doi. 10.1523/JNEUROSCI.4601-04.2005

By:

Baquet, Zachary C.;
Bickford, Paula C.;
Jones, Kevin R.

Publication type:

Article

Small molecule targeting long noncoding RNA GAS5 administered intranasally improves neuronal insulin signaling and decreases neuroinflammation in an aged mouse model.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-022-27126-6

By:

Patel, Rekha S.;
Lui, Ashley;
Hudson, Charles;
Moss, Lauren;
Sparks, Robert P.;
Hill, Shannon E.;
Shi, Yan;
Cai, Jianfeng;
Blair, Laura J.;
Bickford, Paula C.;
Patel, Niketa A.

Publication type:

Article

Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 851, doi. 10.3390/ijms23020851

By:

Rodriguez Ospina, Santiago;
Blazier, Danielle M.;
Criado-Marrero, Marangelie;
Gould, Lauren A.;
Gebru, Niat T.;
Beaulieu-Abdelahad, David;
Wang, Xinming;
Remily-Wood, Elizabeth;
Chaput, Dale;
Stevens Jr., Stanley;
Uversky, Vladimir N.;
Bickford, Paula C.;
Dickey, Chad A.;
Blair, Laura J.

Publication type:

Article

Polyphenol Supplementation Reverses Age-Related Changes in Microglial Signaling Cascades.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6373, doi. 10.3390/ijms22126373

By:

Jalloh, Ahmad;
Flowers, Antwoine;
Hudson, Charles;
Chaput, Dale;
Guergues, Jennifer;
Stevens Jr., Stanley M.;
Bickford, Paula C.

Publication type:

Article

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5442, doi. 10.3390/ijms21155442

By:

Webster, Jack M.;
Darling, April L.;
Sanders, Taylor A.;
Blazier, Danielle M.;
Vidal-Aguiar, Yamile;
Beaulieu-Abdelahad, David;
Plemmons, Drew G.;
Hill, Shannon E.;
Uversky, Vladimir N.;
Bickford, Paula C.;
Dickey, Chad A.;
Blair, Laura J.

Publication type:

Article

Dietary Supplementations as Neuroprotective Therapies: Focus on NT-020 Diet Benefits in a Rat Model of Stroke.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 6, p. 7424, doi. 10.3390/ijms13067424

By:

Kaneko, Yuji;
Cortes, Lourdes;
Sanberg, Cyndy;
Acosta, Sandra;
Bickford, Paula C.;
Borlongan, Cesar V.

Publication type:

Article

Age-related Changes in Cerebellar Noradrenergic Functiona.

Published in:

Annals of the New York Academy of Sciences, 1987, v. 515, n. 1, p. 269, doi. 10.1111/j.1749-6632.1988.tb32996.x

By:

HOFFER, BARRY J.;
ROSE, GREG;
PARFITT, KAREN;
FREEDMAN, ROBERT;
BICKFORD-WIMER, PAULA C.

Publication type:

Article

Blueberry supplementation attenuates microglial activation in hippocampal intraocular grafts to aged hosts.

Published in:

Glia (0894-1491), 2010, v. 58, n. 6, p. 679, doi. 10.1002/glia.20954

By:

Willis, Lauren M.;
Freeman, Linnea;
Bickford, Paula C.;
Quintero, E. Matthew;
Umphlet, Claudia D.;
Moore, Alfred B.;
Goetzl, Laura;
Granholm, Ann-Charlotte

Publication type:

Article

Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Brain from Traumatic Brain Injury-Induced Neurodegeneration and Motor and Cognitive Impairments: Cell Graft Biodistribution and Soluble Factors in Young and Aged Rats.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 1, p. 313, doi. 10.1523/JNEUROSCI.2425-13.2014

By:

Naoki Tajiri;
Acosta, Sandra A.;
Shahaduzzaman, Md;
Hiroto Ishikawa;
Kazutaka Shinozuka;
Pabon, Mibel;
Hernandez-Ontiveros, Diana;
Dae Won Kim;
Metcalf, Christopher;
Staples, Meaghan;
Dailey, Travis;
Vasconcellos, Julie;
Franyuti, Giorgio;
Gould, Lisa;
Patel, Niketa;
Cooper, Denise;
Yuji Kaneko;
Borlongan, Cesar V.;
Bickford, Paula C.

Publication type:

Article

The Soluble Isoform of CX3CL1 Is Necessary for Neuroprotection in a Mouse Model of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 42, p. 14592, doi. 10.1523/JNEUROSCI.0539-12.2012

By:

Morganti, Josh M.;
Nash, Kevin R.;
Grimmig, Bethany A.;
Ranjit, Sonali;
Small, Brent;
Bickford, Paula C.;
Gemma, Carmelina

Publication type:

Article

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 45, p. 16241, doi. 10.1523/JNEUROSCI.3667-11.2011

By:

Rogers, Justin T.;
Morganti, Josh M.;
Bachstetter, Adam D.;
Hudson, Charles E.;
Peters, Melinda M.;
Grimmig, Bethany A.;
Weeber, Edwin J.;
Bickford, Paula C.;
Gemma, Carmelina

Publication type:

Article

NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats.

Published in:

2015

By:

Flowers, Antwoine;
Jea-Young Lee;
Acosta, Sandra;
Hudson, Charles;
Small, Brent;
Sanberg, Cyndy D.;
Bickford, Paula C.;
Lee, Jea-Young

Publication type:

journal article

CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease.

Published in:

Journal of Neuroinflammation, 2011, v. 8, n. 1, p. 9, doi. 10.1186/1742-2094-8-9

By:

Pabon, Mibel M.;
Bachstetter, Adam D.;
Hudson, Charles E.;
Gemma, Carmelina;
Bickford, Paula C.

Publication type:

Article

Erratum: Motor learning in Ts65Dn mice, a model for Down Syndrome.

Published in:

2001

By:

Hyde, Lynn A.;
Crnic, Linda S.;
Pollock, Amber;
Bickford, Paula C.

Publication type:

Correction Notice

Motor learning in Ts65Dn mice, a model for Down syndrome.

Published in:

Developmental Psychobiology, 2001, v. 38, n. 1, p. 33, doi. 10.1002/1098-2302(2001)38:1<33::AID-DEV3>3.0.CO;2-0

By:

Hyde, Lynn A.;
Crnic, Linda S.;
Pollock, Amber;
Bickford, Paula C.

Publication type:

Article

Role of TNFα Induced Inflammation in Delay Eyeblink Conditioning in Young and Aged Rats.

Published in:

Aging & Disease, 2010, v. 1, n. 3, p. 191

By:

Paredes, Daniel;
Acosta, Sandra;
Gemma, Carmelina;
Bickford, Paula C.

Publication type:

Article

Neuron-Microglia Dialogue and Hippocampal Neurogenesis in the Aged Brain.

Published in:

Aging & Disease, 2010, v. 1, n. 3, p. 232

By:

Gemma, Carmelina;
Bachstetter, Adam D.;
Bickford, Paula C.

Publication type:

Article

Effects of nutraceutical intervention on serum proteins in aged rats.

Published in:

GeroScience, 2020, v. 42, n. 2, p. 703, doi. 10.1007/s11357-020-00174-4

By:

Portis, Samantha M.;
Chaput, Dale;
Burroughs, Beau;
Hudson, Charles;
Sanberg, Paul R.;
Bickford, Paula C.

Publication type:

Article

Astaxanthin supplementation modulates cognitive function and synaptic plasticity in young and aged mice.

Published in:

GeroScience, 2019, v. 41, n. 1, p. 77, doi. 10.1007/s11357-019-00051-9

By:

Grimmig, Bethany;
Hudson, Charles;
Moss, Lauren;
Peters, Melinda;
Subbarayan, Meena;
Weeber, Edwin J.;
Bickford, Paula C.

Publication type:

Article

Fractalkine Over Expression Suppresses α-Synuclein-mediated Neurodegeneration.

Published in:

Molecular Therapy, 2015, v. 23, n. 1, p. 17, doi. 10.1038/mt.2014.175

By:

Nash, Kevin R;
Moran, Peter;
Finneran, Dylan J;
Hudson, Charles;
Robinson, Jesse;
Morgan, Dave;
Bickford, Paula C

Publication type:

Article

Immunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson's Disease.

Published in:

Brain Sciences (2076-3425), 2016, v. 6, n. 4, p. 41, doi. 10.3390/brainsci6040041

By:

Grimmig, Bethany;
Bickford, Paula C.;
Morganti, Josh;
Nash, Kevin

Publication type:

Article

Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain.

Published in:

BMC Neuroscience, 2008, v. 9, p. 1, doi. 10.1186/1471-2202-9-22

By:

Bachstetter, Adam D.;
Pabon, Mibel M.;
Cole, Michael J.;
Hudson, Charles E.;
Sanberg, Paul R.;
Willing, Alison E.;
Bickford, Paula C.;
Gemma, Carmelina

Publication type:

Article

Umbilical Cord Blood--Derived Stem Cells and Brain Repair.

Published in:

Annals of the New York Academy of Sciences, 2005, v. 1049, n. 1, p. 67, doi. 10.1196/annals.1334.008

By:

SANBERG, PAUL R.;
WILLING, ALISON E.;
GARBUZOVA‐DAVIS, SVITLANA;
SAPORTA, SAMUEL;
LIU, GUOQING;
SANBERG, CYNDY DAVIS;
BICKFORD, PAULA C.;
KLASKO, STEPHEN K.;
EL‐BADRI, NAGWA S.

Publication type:

Article

Concentration and proteolysis of CX3CL1 may regulate the microglial response to CX3CL1.

Published in:

Glia (0894-1491), 2023, v. 71, n. 2, p. 245, doi. 10.1002/glia.24269

By:

Finneran, Dylan;
Li, Qingyou;
Subbarayan, Meena S.;
Joly‐Amado, Aurelie;
Kamath, Siddharth;
Dengler, Daniela G.;
Gordon, Marcia N.;
Jackson, Michael R.;
Morgan, Dave;
Bickford, Paula C.;
Smith, Layton H.;
Nash, Kevin R.

Publication type:

Article

Anthocyanins and Their Metabolites as Therapeutic Agents for Neurodegenerative Disease.

Published in:

Antioxidants, 2019, v. 8, n. 9, p. 333, doi. 10.3390/antiox8090333

By:

Winter, Aimee N.;
Bickford, Paula C.

Publication type:

Article

Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.628156

By:

Ma, Chao;
Hunt, Jerry B.;
Kovalenko, Andrii;
Liang, Huimin;
Selenica, Maj-Linda B.;
Orr, Michael B.;
Zhang, Bei;
Gensel, John C.;
Feola, David J.;
Gordon, Marcia N.;
Morgan, Dave;
Bickford, Paula C.;
Lee, Daniel C.

Publication type:

Article

Arginase 1 Insufficiency Precipitates Amyloid- β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis.

Published in:

Frontiers in Immunology, 2021, p. N.PAG, doi. 10.3389/fimmu.2020.582998

By:

Ma, Chao;
Hunt, Jerry B.;
Selenica, Maj-Linda B.;
Sanneh, Awa;
Sandusky-Beltran, Leslie A.;
Watler, Mallory;
Daas, Rana;
Kovalenko, Andrii;
Liang, Huimin;
Placides, Devon;
Cao, Chuanhai;
Lin, Xiaoyang;
Orr, Michael B.;
Zhang, Bei;
Gensel, John C.;
Feola, David J.;
Gordon, Marcia N.;
Morgan, Dave;
Bickford, Paula C.;
Lee, Daniel C.

Publication type:

Article

Free radical-dependent nuclear localization of Bcl-2 in the central nervous system of aged rats is not associated with Bcl-2-mediated protection from apoptosis.

Published in:

Journal of Neurochemistry, 2003, v. 87, n. 4, p. 981, doi. 10.1046/j.1471-4159.2003.02092.x

By:

Kaufmann, Joel A.;
Perez, Mike;
WenRu Zhang, Mike;
Bickford, Paula C.;
Holmes, Douglas B.;
Taglialatela, Giulio

Publication type:

Article

T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson's disease.

Published in:

2020

By:

Subbarayan, Meena S.;
Hudson, Charles;
Moss, Lauren D.;
Nash, Kevin R.;
Bickford, Paula C.

Publication type:

journal article

Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice.

Published in:

2020

By:

Winter, Aimee N.;
Subbarayan, Meena S.;
Grimmig, Bethany;
Weesner, Jason A.;
Moss, Lauren;
Peters, Melinda;
Weeber, Edwin;
Nash, Kevin;
Bickford, Paula C.

Publication type:

journal article

The impact of dietary supplement NT-020 with Rhodiola rosea on energy, fatigue, and perceived exertion.

Published in:

Functional Foods in Health & Disease, 2019, v. 9, n. 11, p. 706, doi. 10.31989/ffhd.v9i11.656

By:

Lamadrid, Priscila;
Williams, Danielle K.;
Kilpatrick, Marcus W.;
Bickford, Paula C.;
Sanberg, Cyndy D.

Publication type:

Article

Anti-Human α-Synuclein N-Terminal Peptide Antibody Protects against Dopaminergic Cell Death and Ameliorates Behavioral Deficits in an AAV-α-Synuclein Rat Model of Parkinson’s Disease.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116841

By:

Shahaduzzaman, Md;
Nash, Kevin;
Hudson, Charles;
Sharif, Masroor;
Grimmig, Bethany;
Lin, Xiaoyang;
Bai, Ge;
Liu, Hui;
Ugen, Kenneth E.;
Cao, Chuanhai;
Bickford, Paula C.

Publication type:

Article

Long-Term Upregulation of Inflammation and Suppression of Cell Proliferation in the Brain of Adult Rats Exposed to Traumatic Brain Injury Using the Controlled Cortical Impact Model.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053376

By:

Acosta, Sandra A.;
Tajiri, Naoki;
Shinozuka, Kazutaka;
Ishikawa, Hiroto;
Grimmig, Bethany;
Diamond, David;
Sanberg, Paul R.;
Bickford, Paula C.;
Kaneko, Yuji;
Borlongan, Cesar V.

Publication type:

Article

A Spirulina-Enhanced Diet Provides Neuroprotection in an α-Synuclein Model of Parkinson's Disease.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045256

By:

Pabon, Mibel M.;
Jernberg, Jennifer N.;
Morganti, Josh;
Contreras, Jessika;
Hudson, Charles E.;
Klein, Ronald L.;
Bickford, Paula C.;
Block, Michelle L.

Publication type:

Article

Intravenous Grafts Of Amniotic Fluid-Derived Stem Cells Induce Endogenous Cell Proliferation and Attenuate Behavioral Deficits in Ischemic Stroke Rats.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043779

By:

Tajiri, Naoki;
Acosta, Sandra;
Glover, Loren E.;
Bickford, Paula C.;
Simancas, Alejandra Jacotte;
Yasuhara, Takao;
Date, Isao;
Solomita, Marianna A.;
Antonucci, Ivana;
Stuppia, Liborio;
Kaneko, Yuji;
Borlongan, Cesar V.;
Arumugam, Thiruma V.

Publication type:

Article

Spirulina Promotes Stem Cell Genesis and Protects against LPS Induced Declines in Neural Stem Cell Proliferation.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010496

By:

Bachstetter, Adam D.;
Jernberg, Jennifer;
Schlunk, Andrea;
Vila, Jennifer L.;
Hudson, Charles;
Cole, Michael J.;
Shytle, R. Douglas;
Tan, Jun;
Sanberg, Paul R.;
Sanberg, Cyndy D.;
Borlongan, Cesario;
Kaneko, Yuji;
Tajiri, Naoki;
Gemma, Carmelina;
Bickford, Paula C.

Publication type:

Article

Human Umbilical Cord Blood Treatment in a Mouse Model of ALS: Optimization of Cell Dose.

Published in:

PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002494

By:

Garbuzova-Davis, Svitlana;
Sanberg, Cyndy Davis;
Kuzmin-Nichols, Nicole;
Willing, Alison E.;
Gemma, Carmelina;
Bickford, Paula C.;
Miller, Christina;
Rossi, Robert;
Sanberg, Paul R.

Publication type:

Article

α-MSH and MCH Are Functional Antagonists in a Central Nervous System Auditory Gating Paradigm.

Published in:

Annals of the New York Academy of Sciences, 1993, v. 680, n. 1, p. 571, doi. 10.1111/j.1749-6632.1993.tb19742.x

By:

MILLER, CHRISTINE L.;
HRUBY, VICTOR J.;
MATSUNAGA, TERRY O.;
BICKFORD, PAULA C.

Publication type:

Article

Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury.

Published in:

2018

By:

Patel, Niketa A.;
Moss, Lauren Daly;
Lee, Jea-Young;
Tajiri, Naoki;
Acosta, Sandra;
Hudson, Charles;
Parag, Sajan;
Cooper, Denise R.;
Borlongan, Cesario V.;
Bickford, Paula C.

Publication type:

journal article

Blockade of caspase-1 increases neurogenesis in the aged hippocampus.

Published in:

European Journal of Neuroscience, 2007, v. 26, n. 10, p. 2795, doi. 10.1111/j.1460-9568.2007.05875.x

By:

Gemma, Carmelina;
Bachstetter, Adam D.;
Cole, Michael J.;
Fister, Matthew;
Hudson, Charles;
Bickford, Paula C.

Publication type:

Article

Improvement of memory for context by inhibition of caspase-1 in aged rats.

Published in:

European Journal of Neuroscience, 2005, v. 22, n. 7, p. 1751, doi. 10.1111/j.1460-9568.2005.04334.x

By:

Gemma, Carmelina;
Fister, Matthew;
Hudson, Charles;
Bickford, Paula C.

Publication type:

Article

Dietary blueberry supplementation affects growth but not vascularization of neural transplants.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2008, v. 28, n. 6, p. 1150, doi. 10.1038/jcbfm.2008.3

By:

Willis, Lauren M.;
Small, Brent J.;
Bickford, Paula C.;
Umphlet, Claudia D.;
Moore, Alfred B.;
Granholm, Ann-Charlotte E.

Publication type:

Article

Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response.

Published in:

2017

By:

Flowers, Antwoine;
Bell-Temin, Harris;
Jalloh, Ahmad;
Stevens Jr., Stanley M.;
Bickford, Paula C.;
Stevens, Stanley M Jr

Publication type:

journal article