Found: 95

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  • Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer's disease.

    Published in:
    Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00802-x
    By:
    • Tissot, Cécile;
    • L. Benedet, Andréa;
    • Therriault, Joseph;
    • Pascoal, Tharick A.;
    • Lussier, Firoza Z.;
    • Saha-Chaudhuri, Paramita;
    • Chamoun, Mira;
    • Savard, Melissa;
    • Mathotaarachchi, Sulantha S.;
    • Bezgin, Gleb;
    • Wang, Yi-Ting;
    • Fernandez Arias, Jaime;
    • Rodriguez, Juan Lantero;
    • Snellman, Anniina;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K.;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • De Villers-Sidani, Etienne;
    • Huot, Philippe
    Publication type:
    Article

  • A macaque connectome for large-scale network simulations in TheVirtualBrain.

    Published in:
    Scientific Data, 2019, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41597-019-0129-z
    By:
    • Shen, Kelly;
    • Bezgin, Gleb;
    • Schirner, Michael;
    • Ritter, Petra;
    • Everling, Stefan;
    • McIntosh, Anthony R.
    Publication type:
    Article

  • Employing transfer learning to optimize deep learning models for Alzheimer's disease classification using two tau PET tracers.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082824
    By:
    • Bauer‐Negrini, Guilherme;
    • Povala, Guilherme;
    • Lucchese, Luisa Vieira;
    • Lussier, Firoza Z;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Aguzzoli, Cristiano Schaffer;
    • Soares, Carolina;
    • Zalzale, Hussein;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas Teixeira;
    • Lemaire, Peter Charles;
    • Cabrera, Arlec;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Stevenson, Jenna
    Publication type:
    Article

  • Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer Disease.

    Published in:
    JAMA Network Open, 2023, v. 6, n. 11, p. e2345175, doi. 10.1001/jamanetworkopen.2023.45175
    By:
    • Schaffer Aguzzoli, Cristiano;
    • Ferreira, Pâmela C. L.;
    • Povala, Guilherme;
    • Ferrari-Souza, João Pedro;
    • Bellaver, Bruna;
    • Soares Katz, Carolina;
    • Zalzale, Hussein;
    • Lussier, Firoza Z.;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Leffa, Douglas T.;
    • Scop Medeiros, Marina;
    • Therriault, Joseph;
    • Benedet, Andréa L.;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Rahmouni, Nesrine;
    • Cassa Macedo, Arthur;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Comparative Analysis of the Macroscale Structural Connectivity in the Macaque and Human Brain.

    Published in:
    PLoS Computational Biology, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pcbi.1003529
    By:
    • Goulas, Alexandros;
    • Bastiani, Matteo;
    • Bezgin, Gleb;
    • Uylings, Harry B. M.;
    • Roebroeck, Alard;
    • Stiers, Peter
    Publication type:
    Article

  • A multi-scale layer-resolved spiking network model of resting-state dynamics in macaque visual cortical areas.

    Published in:
    PLoS Computational Biology, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.pcbi.1006359
    By:
    • Schmidt, Maximilian;
    • Bakker, Rembrandt;
    • Shen, Kelly;
    • Bezgin, Gleb;
    • Diesmann, Markus;
    • van Albada, Sacha Jennifer
    Publication type:
    Article

  • In-vivo neuronal dysfunction by Aβ and tau overlaps with brain-wide inflammatory mechanisms in Alzheimer's disease.

    Published in:
    Frontiers in Aging Neuroscience, 2024, p. 01, doi. 10.3389/fnagi.2024.1383163
    By:
    • Sanchez-Rodriguez, Lazaro M.;
    • Khan, Ahmed F.;
    • Adewale, Quadri;
    • Bezgin, Gleb;
    • Therriault, Joseph;
    • Fernandez-Arias, Jaime;
    • Servaes, Stijn;
    • Rahmouni, Nesrine;
    • Tissot, Cécile;
    • Stevenson, Jenna;
    • Hongxiu Jiang;
    • Xiaoqian Chai;
    • Carbonell, Felix;
    • Rosa-Neto, Pedro;
    • Iturria-Medina, Yasser
    Publication type:
    Article

  • Bayesian workflow for the investigation of hierarchical classification models from tau-PET and structural MRI data across the Alzheimer's disease spectrum.

    Published in:
    Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1225816
    By:
    • Belasso, Clyde J.;
    • Zhengchen Cai;
    • Bezgin, Gleb;
    • Pascoal, Tharick;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Tissot, Cécile;
    • Lussier, Firoza;
    • Rosa-Neto, Pedro;
    • Soucy, Jean-Paul;
    • Rivaz, Hassan;
    • Benali, Habib
    Publication type:
    Article

  • Mitochondrial complex I abnormalities underlie neurodegeneration and cognitive decline in Alzheimer's disease.

    Published in:
    European Journal of Neurology, 2022, v. 29, n. 5, p. 1324, doi. 10.1111/ene.15246
    By:
    • Terada, Tatsuhiro;
    • Therriault, Joseph;
    • Kang, Min Su;
    • Savard, Melissa;
    • Pascoal, Tharick Ali;
    • Lussier, Firoza;
    • Tissot, Cecile;
    • Wang, Yi‐Ting;
    • Benedet, Andrea;
    • Poltronetti, Nina Margherita;
    • Ottoy, Julie;
    • Arias, Jaime Frenandez;
    • Bezgin, Gleb;
    • Matsudaira, Takashi;
    • Bunai, Tomoyasu;
    • Obi, Tomokazu;
    • Tsukada, Hideo;
    • Ouchi, Yasuomi;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Confounding Effects of Phase Delays on Causality Estimation.

    Published in:
    PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053588
    By:
    • Vakorin, Vasily A.;
    • Mišić, Bratislav;
    • Krakovska, Olga;
    • Bezgin, Gleb;
    • McIntosh, Anthony R.
    Publication type:
    Article

  • Network Structure Shapes Spontaneous Functional Connectivity Dynamics.

    Published in:
    Journal of Neuroscience, 2015, v. 35, n. 14, p. 5579, doi. 10.1523/JNEUROSCI.4903-14.2015
    By:
    • Shen, Kelly;
    • Hutchison, R. Matthew;
    • Bezgin, Gleb;
    • Everling, Stefan;
    • McIntosh, Anthony R.
    Publication type:
    Article

  • Information Processing Architecture of Functionally Defined Clusters in the Macaque Cortex.

    Published in:
    Journal of Neuroscience, 2012, v. 32, n. 48, p. 17465, doi. 10.1523/JNEUROSCI.2709-12.2012
    By:
    • Shen, Kelly;
    • Bezgin, Gleb;
    • Hutchison, R. Matthew;
    • Gati, Joseph S.;
    • Menon, Ravi S.;
    • Everling, Stefan;
    • Mcintosh, Anthony R.
    Publication type:
    Article

  • Microglial Activation Contributes to Neuropsychiatric Dysfunction in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079969
    By:
    • Aguzzoli, Cristiano Schaffer;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Soares, Carolina;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • Hippocampal subfield volumes and memory performances: associations with stimulus modality and free recall or recognition.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074350
    By:
    • Aumont, Etienne;
    • Bussy, Aurelie;
    • Bezgin, Gleb;
    • Therriault, Joseph;
    • Savard, Melissa;
    • Arias, Jaime Fernandez;
    • Poltronetti, Nina Margherita;
    • Pallen, Vanessa;
    • Thomas, Emilie;
    • Vitali, Paolo;
    • Chakravarty, Mallar;
    • Bedard, Marc‐Andre;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Microglial activation interacts with amyloid‐β to drive longitudinal tau tangle accumulation and cognitive decline.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079188
    By:
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Lussier, Firoza Z;
    • Ferreira, Pamela C.L.;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas Teixeira;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Soares, Carolina;
    • Abbas, Sarah;
    • Rohden, Francieli;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Benedet, Andrea Lessa;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Cohen, Annie;
    • Lopez, Oscar L.
    Publication type:
    Article

  • Increased regional brain inflammation predicts longitudinal brain atrophy in individuals in the Alzheimer's disease continuum.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079000
    By:
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas Teixeira;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Benedet, Andrea Lessa;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Cohen, Ann D.;
    • Lopez, Oscar L.;
    • Tudorascu, Dana;
    • Klunk, William E;
    • Villemagne, Victor L;
    • Karikari, Thomas K;
    • Zimmer, Eduardo R
    Publication type:
    Article

  • Association of reactive astrogliosis and microglial activation with tau pathology in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078423
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Benedet, Andrea Lessa;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Rohden, Francieli;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Potential utility of using both APOEε4 and Aβ positivity to enrich clinical trials of tau‐targeting therapies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079764
    By:
    • Ferrari‐Souza, João Pedro;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Benedet, Andrea Lessa;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • APOEε4 potentiates the effects of Aβ pathology on the deposition of neurofibrillary tangles via tau phosphorylation.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079681
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Benedet, Andrea Lessa;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080098
    By:
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Snellman, Anniina;
    • Rodriguez, Juan Lantero;
    • Stevenson, Alyssa;
    • Arias, Jaime Fernandez;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Bezgin, Gleb;
    • Kunach, Peter;
    • Triana‐Baltzer, Gallen;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Kolb, Hartmuth C.
    Publication type:
    Article

  • Late‐life hypertension acts together with amyloid‐β pathology to promote early cognitive decline.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079952
    By:
    • Da Ros, Lucas Uglione;
    • Ferrari‐Souza, João Pedro;
    • Bastiani, Marco Antônio De;
    • Hauschild, Lucas Augusto;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Benedet, Andrea Lessa;
    • Pascoal, Tharick A.;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • CSF total tau is more closely associated with synaptic dysfunction than overt neurodegeneration.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079855
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • Sex impacts the association of plasma Glial Fibrillary Acidic Protein with neurodegeneration in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076402
    By:
    • Abbas, Sarah;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Ferrari‐Souza, João Pedro;
    • Lussier, Firoza Z;
    • Zalzale, Hussein;
    • Lemaire, Peter Charles;
    • Soares, Carolina;
    • Rohden, Francieli;
    • Aguzzoli, Cristiano Schaffer;
    • Cabrera, Arlec;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Stevenson, Jenna
    Publication type:
    Article

  • Synaptic dysfunction, Tau pathology and Neurodegeneration.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080006
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Rohden, Francieli;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Mapping the effects of functional and structural network reorganization on the tau‐cognition relationship in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078555
    By:
    • Ottoy, Julie;
    • Kang, Min Su;
    • de Wael, Reinder Vos;
    • Park, Bo‐Yong;
    • Bezgin, Gleb;
    • Lussier, Firoza Z;
    • Rahmouni, Nesrine;
    • Stevenson, Jenna;
    • Arias, Jaime Fernandez;
    • Soucy, Jean‐Paul;
    • Gauthier, Serge;
    • Bernhardt, Boris;
    • Black, Sandra E.;
    • Rosa‐Neto, Pedro;
    • Goubran, Maged
    Publication type:
    Article

  • Plasma p‐tau and brain‐derived total tau biomarkers predict longitudinal changes in Aβ, tau, and cognition across the AD continuum.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078070
    By:
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Rodriguez, Juan Lantero;
    • Snellman, Anniina;
    • Leffa, Douglas Teixeira;
    • Ferrari‐Souza, Pedro;
    • Lussier, Firoza Z;
    • Zalzale, Hussein;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Tissot, Cécile;
    • Benedet, Andrea Lessa;
    • Rohden, Francieli;
    • Therriault, Joseph;
    • Abbas, Sarah;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Lopez, Oscar L.;
    • Rahmouni, Nesrine
    Publication type:
    Article

  • Plasma p‐tau231 and p‐tau217 provides information on tau tangle deposition in symptomatic Alzheimer's disease individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076691
    By:
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Therriault, Joseph;
    • Ferrari‐Souza, João Pedro;
    • Tissot, Cécile;
    • Leffa, Douglas Teixeira;
    • Brum, Wagner S.;
    • Benedet, Andrea Lessa;
    • Lussier, Firoza Z;
    • Cabrera, Arlec;
    • Zalzale, Hussein;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Stevenson, Jenna;
    • Triana‐Baltzer, Gallen;
    • Kolb, Hartmuth C.;
    • Rahmouni, Nesrine
    Publication type:
    Article

  • Association of reactive astrogliosis and microglial activation with tau pathology in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.082041
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Benedet, Andrea Lessa;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Rohden, Francieli;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Synaptic dysfunction in the presence of tau tangles is not a strong predictor of atrophy.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081954
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Rohden, Francieli;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081969
    By:
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Snellman, Anniina;
    • Rodriguez, Juan Lantero;
    • Stevenson, Alyssa;
    • Arias, Jaime Fernandez;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Bezgin, Gleb;
    • Kunach, Peter;
    • Triana‐Baltzer, Gallen;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Kolb, Hartmuth C.
    Publication type:
    Article

  • Microglial Activation Contributes to Neuropsychiatric Dysfunction in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081950
    By:
    • Aguzzoli, Cristiano Schaffer;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Soares, Carolina;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • Potential utility of using both APOEε4 and Aβ positivity to enrich clinical trials of tau‐targeting therapies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081933
    By:
    • Ferrari‐Souza, João Pedro;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Benedet, Andrea Lessa;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • CSF total tau is more closely associated with synaptic dysfunction than overt neurodegeneration.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081943
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • APOEε4 potentiates the effects of Aβ pathology on the deposition of neurofibrillary tangles via tau phosphorylation.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081925
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Benedet, Andrea Lessa;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • Microglial activation interacts with amyloid‐β to drive longitudinal tau tangle accumulation and cognitive decline.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081881
    By:
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Lussier, Firoza Z;
    • Ferreira, Pamela C.L.;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas Teixeira;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Soares, Carolina;
    • Abbas, Sarah;
    • Rohden, Francieli;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Benedet, Andrea Lessa;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Cohen, Annie;
    • Lopez, Oscar L.
    Publication type:
    Article

  • Increased regional brain inflammation predicts longitudinal brain atrophy in individuals in the Alzheimer's disease continuum.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081863
    By:
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas Teixeira;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Benedet, Andrea Lessa;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Cohen, Ann D.;
    • Lopez, Oscar L.;
    • Tudorascu, Dana;
    • Klunk, William E;
    • Villemagne, Victor L;
    • Karikari, Thomas K;
    • Zimmer, Eduardo R
    Publication type:
    Article

  • Mapping the effects of functional and structural network reorganization on the tau‐cognition relationship in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081819
    By:
    • Ottoy, Julie;
    • Kang, Min Su;
    • de Wael, Reinder Vos;
    • Park, Bo‐Yong;
    • Bezgin, Gleb;
    • Lussier, Firoza Z;
    • Rahmouni, Nesrine;
    • Stevenson, Jenna;
    • Arias, Jaime Fernandez;
    • Soucy, Jean‐Paul;
    • Gauthier, Serge;
    • Bernhardt, Boris;
    • Black, Sandra E.;
    • Rosa‐Neto, Pedro;
    • Goubran, Maged
    Publication type:
    Article

  • Plasma p‐tau231 and p‐tau217 provides information on tau tangle deposition in symptomatic Alzheimer's disease individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081726
    By:
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Therriault, Joseph;
    • Ferrari‐Souza, João Pedro;
    • Tissot, Cécile;
    • Leffa, Douglas Teixeira;
    • Brum, Wagner S.;
    • Benedet, Andrea Lessa;
    • Lussier, Firoza Z;
    • Cabrera, Arlec;
    • Zalzale, Hussein;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa;
    • Poltronetti, Nina Margherita
    Publication type:
    Article

  • Hippocampal subfield volumes and memory performances: associations with stimulus modality and free recall or recognition.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081648
    By:
    • Aumont, Etienne;
    • Bussy, Aurelie;
    • Bezgin, Gleb;
    • Therriault, Joseph;
    • Savard, Melissa;
    • Arias, Jaime Fernandez;
    • Poltronetti, Nina Margherita;
    • Pallen, Vanessa;
    • Thomas, Emilie;
    • Vitali, Paolo;
    • Chakravarty, Mallar;
    • Bedard, Marc‐Andre;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Plasma and CSF concentrations of N‐terminal tau fragments associate with in vivo neurofibrillary tangle burden.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5343, doi. 10.1002/alz.13119
    By:
    • Lantero‐Rodriguez, Juan;
    • Tissot, Cécile;
    • Snellman, Anniina;
    • Servaes, Stijn;
    • Benedet, Andrea L.;
    • Rahmouni, Nesrine;
    • Montoliu‐Gaya, Laia;
    • Therriault, Joseph;
    • Brum, Wagner S.;
    • Stevenson, Jenna;
    • Lussier, Firoza Z.;
    • Bezgin, Gleb;
    • Macedo, Arthur C.;
    • Chamoun, Mira;
    • Mathotaarachi, Sulantha S.;
    • Pascoal, Tharick A.;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik;
    • Neto, Pedro Rosa;
    • Blennow, Kaj
    Publication type:
    Article

  • Plasma p‐tau231 and p‐tau217 inform on tau tangles aggregation in cognitively impaired individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 4463, doi. 10.1002/alz.13393
    By:
    • Ferreira, Pamela C. L.;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Ferrari‐Souza, João Pedro;
    • Benedet, Andréa L.;
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Leffa, Douglas T.;
    • Brum, Wagner S.;
    • Lussier, Firoza Z.;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Vermeiren, Marie;
    • Macedo, Arthur C.;
    • Cabrera, Arlec;
    • Stevenson, Jenna;
    • Triana‐Baltzer, Gallen;
    • Kolb, Hartmuth;
    • Rahmouni, Nesrine;
    • Klunk, William E.
    Publication type:
    Article

  • Association between tau uptake and verbal fluency converge in language centers.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.068006
    By:
    • Stevenson, Alyssa;
    • Rahmouni, Nesrine;
    • Therriault, Joseph;
    • Stevenson, Jenna;
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Bezgin, Gleb;
    • Chamoun, Mira;
    • Pascoal, Tharick A;
    • Gauthier, Serge;
    • Benedet, Andréa Lessa;
    • Vitali, Paolo;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Adapting to reality: Effect of Online Assessments as Compared to In‐Person Assessments.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067999
    By:
    • Pallen, Vanessa;
    • Rahmouni, Nesrine;
    • Tissot, Cécile;
    • Stevenson, Jenna;
    • Stevenson, Alyssa;
    • Poltronetti, Nina Margherita;
    • Bezgin, Gleb;
    • Lussier, Firoza Z;
    • Therriault, Joseph;
    • Kunach, Peter;
    • Pascoal, Tharick;
    • Servaes, Stijn;
    • Savard, Melissa;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Vitali, Paolo;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Verbal recognition declines in later Braak Stages compared to verbal delayed recall.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067152
    By:
    • Arias, Jaime Fernandez;
    • Therriault, Joseph;
    • Lussier, Firoza Z;
    • Pascoal, Tharick A;
    • Tissot, Cécile;
    • Wang, Yi‐Ting;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Kang, Min Su;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Poltronetti, Nina Margherita;
    • Kunach, Peter;
    • Ottoy, Julie;
    • Stevenson, Alyssa;
    • Mathotaarachchi, Sulantha;
    • Massarweh, Gassan;
    • Vitali, Paolo;
    • Gauthier, Serge
    Publication type:
    Article

  • Neuroinflammation is associated with the rising of early Alzheimer's disease pathology in amyloid‐negative elderly.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068073
    By:
    • Wang, Yi‐Ting;
    • Bezgin, Gleb;
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Stevenson, Jenna;
    • Arias, Jaime Fernandez;
    • Kang, Min Su;
    • Rahmouni, Nesrine;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • TRIAD multi‐dimensional biobank for biomarker discovery.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.067924
    By:
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Stevenson, Alyssa;
    • Pallen, Vanessa;
    • Therriault, Joseph;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Bezgin, Gleb;
    • Pascoal, Tharick A;
    • Vitali, Paolo;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Impact of meningeal and age‐related off‐target binding on longitudinal [<sup>18</sup>F]MK6240 quantification.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.066227
    By:
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Servaes, Stijn;
    • Bezgin, Gleb;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Vermeiren, Marie;
    • Kunach, Peter;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Kang, Min Su;
    • Villemagne, Victor L;
    • Tudorascu, Dana L
    Publication type:
    Article

  • Apolipoprotein E ε4 associates with microglial activation in early Braak regions independently of amyloid‐β and tau.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065731
    By:
    • Ferrari‐Souza, João Pedro;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Leffa, Douglas Teixeira;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Brum, Wagner S.;
    • Benedet, Andréa Lessa;
    • Therriault, Joseph;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa;
    • Poltronetti, Nina Margherita;
    • Souza, Diogo O.;
    • Gauthier, Serge
    Publication type:
    Article

  • Tau phosphorylation is more closely associated with amyloid‐β plaques than with tau neurofibrillary tangles.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.064277
    By:
    • Vermeiren, Marie;
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Pascoal, Tharick A;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Benedet, Andréa Lessa;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Kunach, Peter;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Massarweh, Gassan;
    • Vitali, Paolo;
    • Soucy, Jean‐Paul
    Publication type:
    Article

  • pTau heterogeneity as a measure for disease severity in incipient Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.063749
    By:
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Arias, Jaime Fernandez;
    • Benedet, Andréa Lessa;
    • Chamoun, Mira;
    • Pascoal, Tharick A;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article