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Synthesis of deuterium‐labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes.
Published in:
Journal of Labelled Compounds & Radiopharmaceuticals, 2019, v. 62, n. 5, p. 202, doi. 10.1002/jlcr.3716
By:
- Gan, Xinmin;
- Wilson, Michael W.;
- Beyett, Tyler S.;
- Wen, Bo;
- Sun, Duxin;
- Larsen, Scott D.;
- Tesmer, John J.G.;
- Saltiel, Alan R.;
- Showalter, Hollis D.
Publication type:
Article
Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30258-y
By:
- Beyett, Tyler S.;
- To, Ciric;
- Heppner, David E.;
- Rana, Jaimin K.;
- Schmoker, Anna M.;
- Jang, Jaebong;
- De Clercq, Dries J. H.;
- Gomez, Gabriel;
- Scott, David A.;
- Gray, Nathanael S.;
- Jänne, Pasi A.;
- Eck, Michael J.
Publication type:
Article
Structural Analysis of the Macrocyclic Inhibitor BI‐4020 Binding to EGFR Kinase.
Published in:
ChemMedChem, 2024, v. 19, n. 12, p. 1, doi. 10.1002/cmdc.202300343
By:
- Beyett, Tyler S.;
- Rana, Jaimin K.;
- Schaeffner, Ilse K.;
- Heppner, David E.;
- Eck, Michael J.
Publication type:
Article
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors.
Published in:
Communications Chemistry, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42004-024-01108-3
By:
- Wittlinger, Florian;
- Ogboo, Blessing C.;
- Shevchenko, Ekaterina;
- Damghani, Tahereh;
- Pham, Calvin D.;
- Schaeffner, Ilse K.;
- Oligny, Brandon T.;
- Chitnis, Surbhi P.;
- Beyett, Tyler S.;
- Rasch, Alexander;
- Buckley, Brian;
- Urul, Daniel A.;
- Shaurova, Tatiana;
- May, Earl W.;
- Schaefer, Erik M.;
- Eck, Michael J.;
- Hershberger, Pamela A.;
- Poso, Antti;
- Laufer, Stefan A.;
- Heppner, David E.
Publication type:
Article
Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00204-0
By:
- Nakamura, Ikuko Takeda;
- Kohsaka, Shinji;
- Ikegami, Masachika;
- Ikeuchi, Hiroshi;
- Ueno, Toshihide;
- Li, Kunhua;
- Beyett, Tyler S.;
- Koyama, Takafumi;
- Shimizu, Toshio;
- Yamamoto, Noboru;
- Takahashi, Fumiyuki;
- Takahashi, Kazuhisa;
- Eck, Michael J.;
- Mano, Hiroyuki
Publication type:
Article

Found: 5

Synthesis of deuterium‐labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes.

Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors.

Structural Analysis of the Macrocyclic Inhibitor BI‐4020 Binding to EGFR Kinase.

Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors.

Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer.