Works by Betzel, Christian

Results: 72

Unveiling the structure, function and dynamics of StmPr1 in Stenotrophomonas maltophilia virulence.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06177-5

By:

Sommer, Max;
Negm, Amr;
Outzen, Lasse;
Windhorst, Sabine;
Gabdulkhakov, Azat;
Weber, Wolfgang;
Betzel, Christian

Publication type:

Article

Utilisation of adsorption and desorption for simultaneously improving protein crystallisation success rate and crystal quality.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07308

By:

Yun-Zhu Guo;
Li-Hua Sun;
Oberthuer, Dominik;
Chen-Yan Zhang;
Jian-Yu Shi;
Jiang-Lei Di;
Bao-Liang Zhang;
Hui-Ling Cao;
Yong-Ming Liu;
Jian Li;
Qian Wang;
Huan-Huan Huang;
Jun Liu;
Schulz, Jan-Mirco;
Qiu-Yu Zhang;
Jian-Lin Zhao;
Betzel, Christian;
Jian-Hua He;
Da-Chuan Yin

Publication type:

Article

Protein-crystal detection with a compact multimodal multiphoton microscope.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01275-8

By:

Cheng, Qing-di;
Chung, Hsiang-Yu;
Schubert, Robin;
Chia, Shih-Hsuan;
Falke, Sven;
Mudogo, Celestin Nzanzu;
Kärtner, Franz X.;
Chang, Guoqing;
Betzel, Christian

Publication type:

Article

Editorial: From Apicomplexan Genes to Drug Discovery.

Published in:

Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. 1, doi. 10.3389/fcimb.2021.798754

By:

Wunderlich, Gerhard;
Betzel, Christian;
Wrenger, Carsten

Publication type:

Article

Structural Dynamics and Perspectives of Vitamin B6 Biosynthesis Enzymes in Plasmodium : Advances and Open Questions.

Published in:

Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. 1, doi. 10.3389/fcimb.2021.688380

By:

Barra, Angélica Luana C.;
Ullah, Najeeb;
Morão, Luana G.;
Wrenger, Carsten;
Betzel, Christian;
Nascimento, Alessandro S.

Publication type:

Article

Exploring Nucleation Pathways in Distinct Physicochemical Environments Unveiling Novel Options to Modulate and Optimize Protein Crystallization.

Published in:

Crystals (2073-4352), 2022, v. 12, n. 3, p. 437, doi. 10.3390/cryst12030437

By:

Wang, Mengying;
Barra, Angélica Luana C.;
Brognaro, Hévila;
Betzel, Christian

Publication type:

Article

Multi-Step Concanavalin A Phase Separation and Early-Stage Nucleation Monitored Via Dynamic and Depolarized Light Scattering.

Published in:

Crystals (2073-4352), 2019, v. 9, n. 12, p. 620, doi. 10.3390/cryst9120620

By:

Brognaro, Hévila;
Falke, Sven;
Nzanzu Mudogo, Celestin;
Betzel, Christian

Publication type:

Article

The crystal structure of an ‘All Locked’ nucleic acid duplex.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 19, p. 6729, doi. 10.1093/nar/gkq505

By:

Eichert, André;
Behling, Katja;
Betzel, Christian;
Erdmann, Volker A.;
Fürste, Jens P.;
Förster, Charlotte

Publication type:

Article

Purification and Spectroscopic Analysis of 11S Globulins from Seeds of Cucumis sativus L.

Published in:

Pakistan Journal of Life & Social Sciences, 2017, v. 15, n. 1, p. 37

By:

Bibi, Shamaila;
Khaliq, Binish;
Shah, Kausar Hussain;
Buck, Friedrich;
Munawar, Aisha;
Ali, Zahid;
Iqbal, Sadaf;
Mehmood, Seema;
Betzel, Christian;
Akrem, Ahmed

Publication type:

Article

Characterization and In-Silico Studies on Ubiquitin Protein from Seeds of Sisymbrium irio.

Published in:

Pakistan Journal of Life & Social Sciences, 2017, v. 15, n. 1, p. 51

By:

Khaliq, Binish;
Iqbal, Sadaf;
Falke, Sven;
Buck, Friedrich;
Munawar, Aisha;
Mahmood, Seema;
Betzel, Christian;
Akrem, Ahmed

Publication type:

Article

Crystal structures of the complexes of a group IIA phospholipase A<sub>2</sub> with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding.

Published in:

Proteins, 2006, v. 64, n. 1, p. 89, doi. 10.1002/prot.20970

By:

Singh, Nagendra;
Jabeen, Talat;
Pal, Aritra;
Sharma, Sujata;
Perbandt, Markus;
Betzel, Christian;
Singh, Tej P.

Publication type:

Article

Crystal Structure of a Complex Formed Between Proteolytically-Generated Lactoferrin Fragment and Proteinase K

Published in:

Proteins, 1998, v. 33, n. 1, p. 30

By:

Singh, Tej P.;
Sharma, Sujata;
Kacthikeyan, S.;
Betzel, Christian;
Bhatia, Krishan L.

Publication type:

Article

Structure of a ternary complex of proteinase K, mercury, and a substrate-analogue hexa-peptide at 2.2 Å resolution.

Published in:

Proteins, 1996, v. 25, n. 2, p. 195, doi. 10.1002/(SICI)1097-0134(199606)25:2<195::AID-PROT5>3.0.CO;2-H

By:

Saxena, Ajay K.;
Singh, Tej P.;
Peters, Klaus;
Fittkau, Siegfried;
Visanji, Marcia;
Wilson, Keith S.;
Betzel, Christian

Publication type:

Article

The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD<sup>+</sup> at 2.45 Å resolution.

Published in:

Proteins, 1992, v. 13, n. 4, p. 336, doi. 10.1002/prot.340130406

By:

Mattevi, Andrea;
Obmolova, Galya;
Sokatch, John R.;
Betzel, Christian;
Hol, Wim G. J.

Publication type:

Article

Preliminary Crystallographic Analysis of a Cruciferin Protein from Seeds of Moringa oleifera.

Published in:

Protein Journal, 2014, v. 33, n. 3, p. 253, doi. 10.1007/s10930-014-9558-x

By:

Akrem, Ahmed;
Yousef, Nasser;
Begum, Afshan;
Negm, Amr;
Meyer, Arne;
Perbandt, Markus;
Buck, Friedrich;
Betzel, Christian

Publication type:

Article

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis.

Published in:

FEBS Journal, 2011, v. 278, n. 23, p. 4544, doi. 10.1111/j.1742-4658.2011.08115.x

By:

Kang, Tse Siang;
Georgieva, Dessislava;
Genov, Nikolay;
Murakami, Mário T.;
Sinha, Mau;
Kumar, Ramasamy P.;
Kaur, Punit;
Kumar, Sanjit;
Dey, Sharmistha;
Sharma, Sujata;
Vrielink, Alice;
Betzel, Christian;
Takeda, Soichi;
Arni, Raghuvir K.;
Singh, Tej P.;
Kini, R. Manjunatha

Publication type:

Article

Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose.

Published in:

FEBS Journal, 2009, v. 276, n. 12, p. 3392, doi. 10.1111/j.1742-4658.2009.07065.x

By:

Mishra, Parul;
Kumar, R. Prem;
Ethayathulla, Abdul S.;
Singh, Nagendra;
Sharma, Sujata;
Perbandt, Markus;
Betzel, Christian;
Kaur, Punit;
Srinivasan, Alagiri;
Bhakuni, Vinod;
Singh, Tej P.

Publication type:

Article

Highlight: Of Systems and Structures.

Published in:

Biological Chemistry, 2010, v. 391, n. 7, p. 717, doi. 10.1515/BC.2010.095

By:

Heinz, Dirk W.;
Betzel, Christian;
Wilmanns, Matthias

Publication type:

Article

Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite‐specific drug development.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2022, v. 78, n. 6, p. 232, doi. 10.1107/S2053230X22005350

By:

Moustafa, Amr;
Perbandt, Markus;
Liebau, Eva;
Betzel, Christian;
Falke, Sven

Publication type:

Article

Structural investigation of the thymidine phosphorylase from Salmonella typhimurium in the unliganded state and its complexes with thymidine and uridine.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 3, p. 224, doi. 10.1107/S2053230X1600162X

By:

Balaev, Vladislav V.;
Lashkov, Alexander A.;
Gabdulkhakov, Azat G.;
Dontsova, Maria V.;
Mikhailov, Al'bert M.;
Seregina, Tatiana A.;
Mironov, Alexander S.;
Betzel, Christian

Publication type:

Article

In vivo protein crystallization in combination with highly brilliant radiation sources offers novel opportunities for the structural analysis of post-translationally modified eukaryotic proteins.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 8, p. 929, doi. 10.1107/S2053230X15011450

By:

Duszenko, Michael;
Redecke, Lars;
Mudogo, Celestin Nzanzu;
Sommer, Benjamin Philip;
Mogk, Stefan;
Oberthuer, Dominik;
Betzel, Christian

Publication type:

Article

Introduction to selected articles from the 15th ICCBM.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 7, p. 805, doi. 10.1107/S2053230X15012534

By:

Einspahr, Howard;
Kuta Smatanova, Ivana;
Betzel, Christian;
Mesters, Jeroen

Publication type:

Article

Initiation and modulation of Tau protein phase separation by the drug suramin.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-29846-9

By:

Prince, Prabhu Rajaiah;
Hochmair, Janine;
Brognaro, Hévila;
Gevorgyan, Susanna;
Franck, Maximilian;
Schubert, Robin;
Lorenzen, Kristina;
Yazici, Selin;
Mandelkow, Eckhard;
Wegmann, Susanne;
Betzel, Christian

Publication type:

Article

Structural characterization and antibacterial activity of silver nanoparticles synthesized using a low-molecular-weight Royal Jelly extract.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-17929-y

By:

Gevorgyan, Susanna;
Schubert, Robin;
Falke, Sven;
Lorenzen, Kristina;
Trchounian, Karen;
Betzel, Christian

Publication type:

Article

Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources.

Published in:

Biotechnology for Biofuels, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13068-021-01927-9

By:

Brandt, Sophie C.;
Brognaro, Hévila;
Ali, Arslan;
Ellinger, Bernhard;
Maibach, Katharina;
Rühl, Martin;
Wrenger, Carsten;
Schlüter, Hartmut;
Schäfer, Wilhelm;
Betzel, Christian;
Janssen, Stefan;
Gand, Martin

Publication type:

Article

Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9455, doi. 10.3390/ijms22179455

By:

Knop, Jan;
Lienemann, Tim;
El-Kilani, Haifa;
Falke, Sven;
Krings, Catharina;
Sindalovskaya, Maria;
Bergler, Johannes;
Betzel, Christian;
Hoth, Stefan

Publication type:

Article

Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1–Pdx2 Complex.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 5971, doi. 10.3390/ijms21175971

By:

Ullah, Najeeb;
Andaleeb, Hina;
Mudogo, Celestin Nzanzu;
Falke, Sven;
Betzel, Christian;
Wrenger, Carsten

Publication type:

Article

Protein phase separation and determinants of in cell crystallization.

Published in:

Traffic, 2020, v. 21, n. 2, p. 220, doi. 10.1111/tra.12711

By:

Mudogo, Celestin N.;
Falke, Sven;
Brognaro, Hévila;
Duszenko, Michael;
Betzel, Christian

Publication type:

Article

Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates.

Published in:

EMBO Journal, 2022, v. 41, n. 11, p. 1, doi. 10.15252/embj.2021108882

By:

Hochmair, Janine;
Exner, Christian;
Franck, Maximilian;
Dominguez‐Baquero, Alvaro;
Diez, Lisa;
Brognaro, Hévila;
Kraushar, Matthew L;
Mielke, Thorsten;
Radbruch, Helena;
Kaniyappan, Senthilvelrajan;
Falke, Sven;
Mandelkow, Eckhard;
Betzel, Christian;
Wegmann, Susanne

Publication type:

Article

Isolation and characterization of Bradykinin potentiating peptides from Agkistrodon bilineatus venom.

Published in:

Proteome Science, 2016, v. 14, p. 1, doi. 10.1186/s12953-016-0090-0

By:

Munawar, Aisha;
Zahid, Anum;
Negm, Amr;
Akrem, Ahmed;
Spencer, Patrick;
Betzel, Christian

Publication type:

Article

Bacillus licheniformis Variant DY Proteinase: Specificity in Relation to the Geometry of the Substrate Recognition Site.

Published in:

Current Microbiology, 2005, v. 51, n. 2, p. 71, doi. 10.1007/s00284-004-4465-6

By:

Georgieva, Dessislava;
Genov, Nicolay;
Betzel, Christian

Publication type:

Article

Substrate Specificity of the Highly Alkalophilic Bacterial Proteinase Esperase: Relation to the X-Ray Structure.

Published in:

Current Microbiology, 2001, v. 42, n. 5, p. 368, doi. 10.1007/s002840010231

By:

Georgieva, Dessislava Nikolova;
Stoeva, Stanka;
Voelter, Wolfgang;
Genov, Nicolay;
Betzel, Christian

Publication type:

Article

Tracing transport of protein aggregates in microgravity versus unit gravity crystallization.

Published in:

NPJ Microgravity, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41526-022-00191-x

By:

Martirosyan, Arayik;
Falke, Sven;
McCombs, Deborah;
Cox, Martin;
Radka, Christopher D.;
Knop, Jan;
Betzel, Christian;
DeLucas, Lawrence J.

Publication type:

Article

Enzyme activity and structural features of three single-domain phloem cyclophilins from Brassica napus.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45856-y

By:

Hanhart, Patrizia;
Falke, Sven;
Garbe, Marcel;
Rose, Victoria;
Thieß, Melanie;
Betzel, Christian;
Kehr, Julia

Publication type:

Article

Features of "All LNA" Duplexes Showing a New Type of Nucleic Acid Geometry.

Published in:

Journal of Nucleic Acids, 2012, p. 1, doi. 10.1155/2012/156035

By:

Förster, Charlotte;
Eichert, André;
Oberthür, Dominik;
Betzel, Christian;
Geßner, Reinhard;
Nitsche, Andreas;
Fürste, Jens P.

Publication type:

Article

Structural basis for branching-enzyme activity of glycoside hydrolase family 57: Structure and stability studies of a novel branching enzyme from the hyperthermophilic archaeon Thermococcus Kodakaraensis KOD1.

Published in:

Proteins, 2011, v. 79, n. 2, p. 547, doi. 10.1002/prot.22902

By:

Santos, Camila R.;
Tonoli, Celisa C. C.;
Trindade, Daniel M.;
Betzel, Christian;
Takata, Hiroki;
Kuriki, Takashi;
Kanai, Tamotsu;
Imanaka, Tadayuki;
Arni, Raghuvir K.;
Murakami, Mário T.

Publication type:

Article

Proteome analysis of snake venom toxins: pharmacological insights.

Published in:

Expert Review of Proteomics, 2008, v. 5, n. 6, p. 787, doi. 10.1586/14789450.5.6.787

By:

Georgieva, Dessislava;
Arni, Raghuvir K.;
Betzel, Christian

Publication type:

Article

Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity.

Published in:

Journal of Neurochemistry, 2016, v. 137, n. 1, p. 88, doi. 10.1111/jnc.13514

By:

Falker, Clemens;
Hartmann, Alexander;
Guett, Inga;
Dohler, Frank;
Altmeppen, Hermann;
Betzel, Christian;
Schubert, Robin;
Thurm, Dana;
Wegwitz, Florian;
Joshi, Pooja;
Verderio, Claudia;
Krasemann, Susanne;
Glatzel, Markus

Publication type:

Article

Latest methods of fluorescence-based protein crystal identification.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 2, p. 121, doi. 10.1107/S2053230X15000114

By:

Meyer, Arne;
Betzel, Christian;
Pusey, Marc

Publication type:

Article

Systematic analysis of protein-detergent complexes applying dynamic light scattering to optimize solutions for crystallization trials.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 1, p. 75, doi. 10.1107/S2053230X14027149

By:

Meyer, Arne;
Dierks, Karsten;
Hussein, Rana;
Brillet, Karl;
Brognaro, Hevila;
Betzel, Christian

Publication type:

Article

Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer.

Published in:

International Journal of Cancer, 2020, v. 146, n. 6, p. 1618, doi. 10.1002/ijc.32567

By:

Konczalla, Leonie;
Perez, Daniel R.;
Wenzel, Nadine;
Wolters‐Eisfeld, Gerrit;
Klemp, Clarissa;
Lüddeke, Johanna;
Wolski, Annika;
Landschulze, Dirk;
Meier, Chris;
Buchholz, Anika;
Yao, Dichao;
Hofmann, Bianca T.;
Graß, Julia K.;
Spriestersbach, Sarah L.;
Grupp, Katharina;
Schumacher, Udo;
Betzel, Christian;
Kapis, Svetlana;
Nuguid, Theresa;
Steinberg, Pablo

Publication type:

Article

Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.

Published in:

Nature Communications, 2015, v. 6, n. 4, p. 6923, doi. 10.1038/ncomms7923

By:

Oberthür, Dominik;
Achenbach, John;
Gabdulkhakov, Azat;
Buchner, Klaus;
Maasch, Christian;
Falke, Sven;
Rehders, Dirk;
Klussmann, Sven;
Betzel, Christian

Publication type:

Article

Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-51787-0

By:

Alves França, Bruno;
Falke, Sven;
Rohde, Holger;
Betzel, Christian

Publication type:

Article

Complete structure determination of N-acetyl- D-galactosamine-binding mistletoe lectin-3 from Viscum album L. album.

Published in:

Journal of Peptide Science, 2005, v. 11, n. 6, p. 289, doi. 10.1002/psc.627

By:

Wacker, Roland;
Stoeva, Stanka;
Betzel, Christian;
Voelter, Wolfgang

Publication type:

Article

Multi‐channel <italic>in situ</italic> dynamic light scattering instrumentation enhancing biological small‐angle X‐ray scattering experiments at the PETRA III beamline P12.

Published in:

Journal of Synchrotron Radiation, 2018, v. 25, n. 2, p. 361, doi. 10.1107/S1600577517017568

By:

Falke, Sven;
Betzel, Christian;
Dierks, Karsten;
Blanchet, Clement;
Graewert, Melissa;
Meijers, Rob;
Svergun, Dmitri;
Cipriani, Florent

Publication type:

Article

The XBI BioLab for life science experiments at the European XFEL.

Published in:

Journal of Applied Crystallography, 2021, v. 54, n. 1, p. 7, doi. 10.1107/S1600576720013989

By:

Han, Huijong;
Round, Ekaterina;
Schubert, Robin;
Gül, Yasmin;
Makroczyová, Jana;
Meza, Domingo;
Heuser, Philipp;
Aepfelbacher, Martin;
Barák, Imrich;
Betzel, Christian;
Fromme, Petra;
Kursula, Inari;
Nissen, Poul;
Tereschenko, Elena;
Schulz, Joachim;
Uetrecht, Charlotte;
Ulicný, Jozef;
Wilmanns, Matthias;
Hajdu, Janos;
Lamzin, Victor S.

Publication type:

Article

Reliably distinguishing protein nanocrystals from amorphous precipitate by means of depolarized dynamic light scattering.

Published in:

Journal of Applied Crystallography, 2015, v. 48, n. 5, p. 1476, doi. 10.1107/S1600576715014740

By:

Schubert, Robin;
Meyer, Arne;
Dierks, Karsten;
Kapis, Svetlana;
Reimer, Rudolph;
Einspahr, Howard;
Perbandt, Markus;
Betzel, Christian

Publication type:

Article

Flip-Flop Hydrogen Bonds in β-Cyclodextrin-A Generally Valid Principle in Polysaccharides?

Published in:

Angewandte Chemie International Edition, 1983, v. 22, n. 11, p. 883, doi. 10.1002/anie.198308831

By:

Saenger, Wolfram;
Betzel, Christian;
Hingerty, Brian;
Brown, George M.

Publication type:

Article

The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91536-1

By:

Werner, Nadine;
Petersen, Katrin;
Vollstedt, Christel;
Garcia, Pablo Perez;
Chow, Jennifer;
Ferrer, Manuel;
Fernandez-Lopez, Laura;
Falke, Sven;
Perbandt, Markus;
Hinrichs, Winfried;
Betzel, Christian;
Streit, Wolfgang R.

Publication type:

Article

High-resolution crystal structure and biochemical characterization of a GH11 endoxylanase from Nectria haematococca.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72644-w

By:

Andaleeb, Hina;
Ullah, Najeeb;
Falke, Sven;
Perbandt, Markus;
Brognaro, Hévila;
Betzel, Christian

Publication type:

Article