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Early Biomarker-Guided Prediction of Bloodstream Infection in Critically Ill Patients: C-Reactive Protein, Procalcitonin, and Leukocytes.
Published in:
Open Forum Infectious Diseases, 2022, v. 9, n. 10, p. 1, doi. 10.1093/ofid/ofac467
By:
- Hertz, Frederik Boetius;
- Ahlström, Magnus G;
- Bestle, Morten H;
- Hein, Lars;
- Mohr, Thomas;
- Lundgren, Jens D;
- Galle, Tina;
- Andersen, Mads Holmen;
- Murray, Daniel;
- Lindhardt, Anne;
- Itenov, Theis Skovsgaard;
- Jensen, Jens Ulrik Staehr
Publication type:
Article
Self-Rated Health as a Predictor of Death after Two Years: The Importance of Physical and Mental Wellbeing Postintensive Care.
Published in:
BioMed Research International, 2017, v. 2017, p. 1, doi. 10.1155/2017/5192640
By:
- Vejen, Marie;
- Bjorner, Jakob B.;
- Bestle, Morten H.;
- Lindhardt, Anne;
- Jensen, Jens U.
Publication type:
Article
Hypernatremia in hospitalised adult patients: A protocol for a scoping review.
Published in:
Acta Anaesthesiologica Scandinavica, 2024, v. 68, n. 10, p. 1541, doi. 10.1111/aas.14491
By:
- Wichmann, Sine;
- Rønhøj, Rasmus;
- Ellekjær, Karen L.;
- Møller, Morten Hylander;
- Bestle, Morten H.
Publication type:
Article
Fluid administration and fluid accumulation in intensive care units—Protocol for an international inception cohort study (FLUID‐ICU).
Published in:
Acta Anaesthesiologica Scandinavica, 2024, v. 68, n. 8, p. 1120, doi. 10.1111/aas.14464
By:
- Molin, Clara;
- Wichmann, Sine;
- Schønemann‐Lund, Martin;
- Møller, Morten H.;
- Bestle, Morten H.
Publication type:
Article
Pupillary dilation velocity is reduced in intensive care unit patients with septic shock.
Published in:
Acta Anaesthesiologica Scandinavica, 2024, v. 68, n. 1, p. 56, doi. 10.1111/aas.14327
By:
- Uhrenholt, Stine;
- Linér, Signe Maria;
- Stokholm, Jannik;
- Christensen, Thomas;
- Bestle, Morten H.
Publication type:
Article
Mild induced hypothermia and coagulation and platelet function in patients with septic shock: Secondary outcome of a randomized trial.
Published in:
Acta Anaesthesiologica Scandinavica, 2023, v. 67, n. 7, p. 909, doi. 10.1111/aas.14254
By:
- Itenov, Theis S.;
- Kromann, Maria E.;
- Ostrowski, Sisse R.;
- Bestle, Morten H.;
- Mohr, Thomas;
- Gyldensted, Louise;
- Lindhardt, Anne;
- Thormar, Katrin;
- Sessler, Daniel I.;
- Juffermans, Nicole P.;
- Lundgren, Jens D.;
- Jensen, Jens‐Ulrik
Publication type:
Article
Novel subgroups in acute respiratory failure based on the trajectories of three endotheliopathy biomarkers: A cohort study.
Published in:
Acta Anaesthesiologica Scandinavica, 2023, v. 67, n. 7, p. 896, doi. 10.1111/aas.14246
By:
- Schønemann‐Lund, Martin;
- Itenov, Theis S.;
- Larsson, Johan E.;
- Lindegaard, Birgitte;
- Johansson, Pär I.;
- Bestle, Morten H.
Publication type:
Article
PaCO<sub>2</sub> trajectories in mechanically ventilated patients with COVID‐19: A population‐based cohort study.
Published in:
Acta Anaesthesiologica Scandinavica, 2023, v. 67, n. 6, p. 779, doi. 10.1111/aas.14233
By:
- Berg, Ronan M. G.;
- Ronit, Andreas;
- Haase, Nicolai;
- Møller, Morten Hylander;
- Kristiansen, Klaus T.;
- Jonassen, Trine;
- Wamberg, Christian;
- Andreasen, Anne Sofie;
- Mohr, Thomas;
- Bestle, Morten H.;
- Jørgensen, Vibeke L.;
- Hammer, Niels R.;
- Mitchell, Anja U.;
- Smitt, Margit;
- Greve, Anders Møller;
- Nyeland, Martin Erik;
- Jensen, Britt Wang;
- Andreasen, Anne Helms;
- Petersen, Janne;
- Solem, Espen Jimenez
Publication type:
Article
Goal‐directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A randomised, blinded trial (GODIF trial—First version).
Published in:
Acta Anaesthesiologica Scandinavica, 2023, v. 67, n. 4, p. 470, doi. 10.1111/aas.14196
By:
- Wichmann, Sine;
- Schønemann‐Lund, Martin;
- Perner, Anders;
- Itenov, Theis S.;
- Lange, Theis;
- Gluud, Christian;
- Berthelsen, Rasmus E.;
- Brøchner, Anne C.;
- Wiis, Jørgen;
- Bestle, Morten H.
Publication type:
Article
Bioimpedance as a measure of fluids in patients with septic shock. A prospective observational study.
Published in:
Acta Anaesthesiologica Scandinavica, 2023, v. 67, n. 3, p. 319, doi. 10.1111/aas.14180
By:
- Madsen, Janne Meisner;
- Itenov, Theis S.;
- Koch, Ellen Bjerre;
- Bestle, Morten H.
Publication type:
Article
Agents intervening against delirium in the intensive care unit trial—Protocol for a secondary Bayesian analysis.
Published in:
Acta Anaesthesiologica Scandinavica, 2022, v. 66, n. 7, p. 898, doi. 10.1111/aas.14091
By:
- Andersen‐Ranberg, Nina;
- Poulsen, Lone M.;
- Perner, Anders;
- Hästbacka, Johanna;
- Morgan, Matthew P. G.;
- Citerio, Giuseppe;
- Oxenbøll‐Collet, Marie;
- Weber, Sven‐Olaf;
- Andreasen, Anne Sofie;
- Bestle, Morten H.;
- Uslu, Bülent;
- Pedersen, Helle B. S.;
- Nielsen, Louise G.;
- Damgaard, Kjeld;
- Jensen, Troels B.;
- Sommer, Trine;
- Dey, Nilanjan;
- Mathiesen, Ole;
- Granholm, Anders
Publication type:
Article
Rapid response teams—how and who? A protocol for a randomised clinical trial evaluating the composition of the efferent limb of the rapid response system.
Published in:
Acta Anaesthesiologica Scandinavica, 2022, v. 66, n. 3, p. 401, doi. 10.1111/aas.14017
By:
- Føns‐Sønderskov, Morten B.;
- Subbe, Chris;
- Kodal, Anne Marie;
- Bunkenborg, Gitte;
- Bestle, Morten H.
Publication type:
Article
LASSO regression shows histidine and sphingosine 1 phosphate are linked to both sepsis mortality and endothelial damage.
Published in:
European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-023-01612-7
By:
- Johansson, Pär I.;
- Henriksen, Hanne H.;
- Karvelsson, Sigurður T.;
- Rolfsson, Óttar;
- Schønemann-Lund, Martin;
- Bestle, Morten H.;
- McGarrity, Sarah
Publication type:
Article
Bioimpedance and Duration of Organ Dysfunction in Septic Shock—A Prospective Observational Study.
Published in:
Journal of Intensive Care Medicine, 2023, v. 38, n. 10, p. 966, doi. 10.1177/08850666231175819
By:
- Koch, Ellen Bjerre;
- Madsen, Janne M.;
- Wichmann, Sine;
- Bestle, Morten H.;
- Itenov, Theis S.
Publication type:
Article
Prostacyclin in Intubated Patients with COVID-19 and Severe Endotheliopathy: A Multicenter, Randomized Clinical Trial.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2022, v. 205, n. 3, p. 324, doi. 10.1164/rccm.202108-1855OC
By:
- Johansson, Pär I.;
- Søe-Jensen, Peter;
- Bestle, Morten H.;
- Clausen, Niels E.;
- Kristiansen, Klaus T.;
- Lange, Theis;
- Stensballe, Jakob;
- Perner, Anders
Publication type:
Article
Oxygenation targets in ICU patients with COVID‐19: A post hoc subgroup analysis of the HOT‐ICU trial.
Published in:
Acta Anaesthesiologica Scandinavica, 2022, v. 66, n. 1, p. 76, doi. 10.1111/aas.13977
By:
- Rasmussen, Bodil S.;
- Klitgaard, Thomas L.;
- Perner, Anders;
- Brand, Björn A.;
- Hildebrandt, Thomas;
- Siegemund, Martin;
- Hollinger, Alexa;
- Aagaard, Søren R.;
- Bestle, Morten H.;
- Marcussen, Klaus V.;
- Brøchner, Anne C.;
- Sølling, Christoffer G.;
- Poulsen, Lone M.;
- Laake, Jon H.;
- Aslam, Tayyba N.;
- Bäcklund, Minna;
- Okkonen, Marjatta;
- Morgan, Matthew;
- Sharman, Mike;
- Lange, Theis
Publication type:
Article
Handling oxygenation targets in ICU patients with COVID-19-Protocol and statistical analysis plan in the HOT-COVID trial.
Published in:
2021
By:
- Mølgaard Nielsen, Frederik;
- Lass Klitgaard, Thomas;
- Crescioli, Elena;
- Rosborg Aagaard, Søren;
- Andreasen, Anne Sofie;
- Musaeus Poulsen, Lone;
- Siegemund, Martin;
- Craveiro Brøchner, Anne;
- Bestle, Morten H.;
- Andi Iversen, Susanne;
- Brand, Björn A.;
- Laake, Jon Henrik;
- Grøfte, Thorbjørn;
- Hildebrandt, Thomas;
- Lange, Theis;
- Perner, Anders;
- Lilleholt Schjørring, Olav;
- Steen Rasmussen, Bodil;
- Klitgaard, Thomas Lass;
- Aagaard, Søren Rosborg
Publication type:
journal article
Bioimpedance as a measure of fluid status in critically ill patients: A systematic review.
Published in:
Acta Anaesthesiologica Scandinavica, 2021, v. 65, n. 9, p. 1155, doi. 10.1111/aas.13924
By:
- Madsen, Janne M.;
- Wichmann, Sine;
- Bestle, Morten H.;
- Itenov, Theis S.
Publication type:
Article
Cardiac arrhythmias in critically ill patients with coronavirus disease 2019: A retrospective population-based cohort study.
Published in:
2021
By:
- Wetterslev, Mik;
- Jacobsen, Peter Karl;
- Hassager, Christian;
- Jøns, Christian;
- Risum, Niels;
- Pehrson, Steen;
- Bastiansen, Anders;
- Andreasen, Anne Sofie;
- Tjelle Kristiansen, Klaus;
- Bestle, Morten H.;
- Mohr, Thomas;
- Møller‐Sørensen, Hasse;
- Perner, Anders;
- Kristiansen, Klaus Tjelle;
- Møller-Sørensen, Hasse
Publication type:
journal article
Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia (COVID STEROID) trial-Protocol and statistical analysis plan.
Published in:
2020
By:
- Petersen, Marie Warrer;
- Meyhoff, Tine Sylvest;
- Helleberg, Marie;
- Kjær, Maj‐Brit Nørregaard;
- Granholm, Anders;
- Hjortsø, Carl Johan Steensen;
- Jensen, Thomas Steen;
- Møller, Morten Hylander;
- Hjortrup, Peter Buhl;
- Wetterslev, Mik;
- Vesterlund, Gitte Kingo;
- Russell, Lene;
- Jørgensen, Vibeke Lind;
- Tjelle, Klaus;
- Benfield, Thomas;
- Ulrik, Charlotte Suppli;
- Andreasen, Anne Sofie;
- Mohr, Thomas;
- Bestle, Morten H.;
- Poulsen, Lone Musaeus
Publication type:
journal article
The Agents Intervening against Delirium in the Intensive Care Unit Trial (AID-ICU trial): A detailed statistical analysis plan.
Published in:
2020
By:
- Andersen‐Ranberg, Nina;
- Poulsen, Lone M.;
- Perner, Anders;
- Wetterslev, Jørn;
- Mathiesen, Ole;
- Mortensen, Camilla B.;
- Estrup, Stine;
- Ebdrup, Bjørn H.;
- Hästbacka, Johanna;
- Citerio, Giuseppe;
- Caballero, Jesus;
- Morgan, Matthew P. G.;
- Oxenbøll‐Collet, Marie;
- Weber, Sven‐Olaf;
- Sofie Andreasen, Anne;
- Bestle, Morten H.;
- Pedersen, Helle B. S.;
- Nielsen, Louise G.;
- Uslu, Bülent;
- Jensen, Troels B.
Publication type:
journal article
Loop diuretics in adult intensive care patients with fluid overload: A protocol for a systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis.
Published in:
2020
By:
- Wichmann, Sine;
- Barbateskovic, Marija;
- Lindschou, Jane;
- Gluud, Christian;
- Perner, Anders;
- Bestle, Morten H.
Publication type:
journal article
Efficacy and safety of iloprost in patients with septic shock-induced endotheliopathy-Protocol for the multicenter randomized, placebo-controlled, blinded, investigator-initiated trial.
Published in:
2020
By:
- Bestle, Morten H.;
- Clausen, Niels E.;
- Søe‐Jensen, Peter;
- Kristiansen, Klaus T.;
- Lange, Theis;
- Johansson, Pär I.;
- Stensballe, Jakob;
- Perner, Anders;
- Søe-Jensen, Peter
Publication type:
journal article
Predicting recovery from acute kidney injury in critically ill patients: development and validation of a prediction model.
Published in:
Critical Care & Resuscitation, 2018, v. 20, n. 1, p. 54, doi. 10.1016/s1441-2772(23)00733-0
By:
- Itenov, Theis S.;
- Ehrenfried Berthelsen, Rasmus;
- Jensen, Jens-Ulrik;
- Gerds, Thomas A.;
- Pedersen, Lars M.;
- Strange, Ditte;
- Thormar, Katrin;
- Løken, Jesper;
- Andersen, Mads H.;
- Tousi, Hamid;
- Reiter, Nanna;
- Lundgren, Jens D.;
- Bestle, Morten H.
Publication type:
Article
Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
Published in:
Intensive Care Medicine, 2024, v. 50, n. 4, p. 614, doi. 10.1007/s00134-024-07357-z
By:
- Pickkers, Peter;
- Angus, Derek C.;
- Bass, Kristie;
- Bellomo, Rinaldo;
- van den Berg, Erik;
- Bernholz, Juliane;
- Bestle, Morten H.;
- Doi, Kent;
- Doig, Chistopher J.;
- Ferrer, Ricard;
- Francois, Bruno;
- Gammelager, Henrik;
- Pedersen, Ulf Goettrup;
- Hoste, Eric;
- Iversen, Susanne;
- Joannidis, Michael;
- Kellum, John A.;
- Liu, Kathleen;
- Meersch, Melanie;
- Mehta, Ravindra
Publication type:
Article
Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
Published in:
Intensive Care Medicine, 2024, v. 50, n. 1, p. 68, doi. 10.1007/s00134-023-07271-w
By:
- Pickkers, Peter;
- Angus, Derek C.;
- Bass, Kristie;
- Bellomo, Rinaldo;
- van den Berg, Erik;
- Bernholz, Juliane;
- Bestle, Morten H.;
- Doi, Kent;
- Doig, Chistopher J.;
- Ferrer, Ricard;
- Francois, Bruno;
- Gammelager, Henrik;
- Pedersen, Ulf Goettrup;
- Hoste, Eric;
- Iversen, Susanne;
- Joannidis, Michael;
- Kellum, John A.;
- Liu, Kathleen;
- Meersch, Melanie;
- Mehta, Ravindra
Publication type:
Article
A recovery program to improve quality of life, sense of coherence and psychological health in ICU survivors: a multicenter randomized controlled trial, the RAPIT study.
Published in:
2016
By:
- Jensen, Janet;
- Egerod, Ingrid;
- Bestle, Morten;
- Christensen, Doris;
- Elklit, Ask;
- Hansen, Randi;
- Knudsen, Heidi;
- Grode, Louise;
- Overgaard, Dorthe;
- Jensen, Janet F;
- Bestle, Morten H;
- Christensen, Doris F;
- Hansen, Randi L;
- Grode, Louise B
Publication type:
journal article
Existing Data Sources in Clinical Epidemiology: Database of Community Acquired Infections Requiring Hospital Referral in Eastern Denmark (DCAIED) 2018–2021.
Published in:
Clinical Epidemiology, 2023, v. 15, p. 939, doi. 10.2147/CLEP.S413403
By:
- Holler, Jon Gitz;
- Jensen, Jens Ulrik Stæhr;
- Engsig, Frederik Neess;
- Bestle, Morten H;
- Lindegaard, Birgitte;
- Rasmussen, Jens Henning;
- Bundgaard, Henning;
- Nielsen, Finn Erland;
- Iversen, Kasper Karmark;
- Larsen, Jesper Juul;
- Holzknecht, Barbara Juliane;
- Boel, Jonas;
- Sivapalan, Pradeesh;
- Itenov, Theis Skovsgaard
Publication type:
Article
Endotheliopathy is associated with slower liberation from mechanical ventilation: a cohort study.
Published in:
2022
By:
- Schønemann-Lund, Martin;
- Itenov, Theis S.;
- Larsson, Johan E.;
- Lindegaard, Birgitte;
- Johansson, Pär I.;
- Bestle, Morten H.
Publication type:
journal article
Hyaluronic Acid Assays: Turbidimetric or Enzyme-Based Immune Assay? A Method Comparison Study.
Published in:
2016
By:
- Itenov, Theis S.;
- Kirkby, Nikolai S.;
- Bestle, Morten H.;
- Nilsson, Anna C.;
- Erlandsen, Erland J.;
- Peters, Lars;
- Jensen, Jens‐Ulrik;
- Jensen, Jens-Ulrik
Publication type:
journal article
Iloprost and Organ Dysfunction in Adults With Septic Shock and Endotheliopathy: A Randomized Clinical Trial.
Published in:
JAMA Network Open, 2024, v. 7, n. 9, p. e2432444, doi. 10.1001/jamanetworkopen.2024.32444
By:
- Bestle, Morten H.;
- Stensballe, Jakob;
- Lange, Theis;
- Clausen, Niels E.;
- Søe-Jensen, Peter;
- Pedersen, Kristine Holst;
- Gybel-Brask, Mikkel;
- Kjær, Maj-Brit N.;
- Steensen, Christian Overgaard;
- Jensen, Diana Bertelsen;
- Gärtner, Rune;
- Schønemann-Lund, Martin;
- Kristiansen, Klaus T.;
- Lindhardt, Anne;
- Johansson, Pär I.;
- Perner, Anders
Publication type:
Article
Meralgia Paresthetica after Prone Positioning Ventilation in the Intensive Care Unit.
Published in:
Case Reports in Critical Care, 2016, p. 1, doi. 10.1155/2016/7263201
By:
- Juhl, Christian Svendsen;
- Ballegaard, Martin;
- Bestle, Morten H.;
- Tfelt-Hansen, Peer
Publication type:
Article
Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.
Published in:
JAMA: Journal of the American Medical Association, 2021, v. 326, n. 18, p. 1807, doi. 10.1001/jama.2021.18295
By:
- Munch, Marie W.;
- Myatra, Sheila N.;
- Vijayaraghavan, Bharath Kumar Tirupakuzhi;
- Saseedharan, Sanjith;
- Benfield, Thomas;
- Wahlin, Rebecka R.;
- Rasmussen, Bodil S.;
- Andreasen, Anne Sofie;
- Poulsen, Lone M.;
- Cioccari, Luca;
- Khan, Mohd S.;
- Kapadia, Farhad;
- Divatia, Jigeeshu V.;
- Brøchner, Anne C.;
- Bestle, Morten H.;
- Helleberg, Marie;
- Michelsen, Jens;
- Padmanaban, Ajay;
- Bose, Neeta;
- Møller, Anders
Publication type:
Article
Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial.
Published in:
2019
By:
- Laterre, Pierre-Francois;
- Berry, Scott M.;
- Blemings, Allan;
- Carlsen, Jan E.;
- François, Bruno;
- Graves, Todd;
- Jacobsen, Karsten;
- Lewis, Roger J.;
- Opal, Steven M.;
- Perner, Anders;
- Pickkers, Peter;
- Russell, James A.;
- Windeløv, Nis A.;
- Yealy, Donald M.;
- Asfar, Pierre;
- Bestle, Morten H.;
- Muller, Grégoire;
- Bruel, Cédric;
- Brulé, Noëlle;
- Decruyenaere, Johan
Publication type:
journal article
ABO blood types and sepsis mortality.
Published in:
Annals of Intensive Care, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13613-021-00844-2
By:
- Itenov, Theis S.;
- Sessler, Daniel I.;
- Khanna, Ashish K.;
- Ostrowski, Sisse R.;
- Johansson, Pär I.;
- Erikstrup, Christian;
- Pedersen, Ole B.;
- Rygård, Sofie L.;
- Holst, Lars B.;
- Bestle, Morten H.;
- Hein, Lars;
- Lindhardt, Anne;
- Tousi, Hami;
- Andersen, Mads H.;
- Mohr, Thomas;
- Lundgren, Jens D.;
- Jensen, Jens-Ulrik
Publication type:
Article
Improving patient outcomes following vital sign monitoring protocol failure: A retrospective cohort study.
Published in:
Health Science Reports, 2024, v. 7, n. 5, p. 1, doi. 10.1002/hsr2.1754
By:
- Seitz‐Rasmussen, H. E. Sebastian;
- Føns‐Sønderskov, Morten;
- Kodal, Anne‐Marie;
- Bestle, Morten H.
Publication type:
Article
Nurses' Experiences and Perceptions of two Early Warning Score systems to Identify Patient Deterioration—A Focus Group Study.
Published in:
Nursing Open, 2021, v. 8, n. 4, p. 1788, doi. 10.1002/nop2.821
By:
- Langkjaer, Caroline S.;
- Bove, Dorthe G.;
- Nielsen, Pernille B.;
- Iversen, Kasper K.;
- Bestle, Morten H.;
- Bunkenborg, Gitte
Publication type:
Article
Duration of acute kidney injury in critically ill patients.
Published in:
Annals of Intensive Care, 2018, v. 8, n. 1, p. 1, doi. 10.1186/s13613-018-0374-x
By:
- Federspiel, Christine K.;
- Itenov, Theis S.;
- Mehta, Kala;
- Hsu, Raymond K.;
- Bestle, Morten H.;
- Liu, Kathleen D.
Publication type:
Article

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