Works by Besser, Michal J.

Results: 30

Locally produced CD19 CAR T cells leading to clinical remissions in medullary and extramedullary relapsed acute lymphoblastic leukemia.

Published in:

American Journal of Hematology, 2018, v. 93, n. 12, p. 1485, doi. 10.1002/ajh.25274

By:

Jacoby, Elad;
Bielorai, Bella;
Avigdor, Abraham;
Itzhaki, Orit;
Hutt, Daphna;
Nussboim, Vered;
Meir, Amilia;
Kubi, Adva;
Levy, Michal;
Zikich, Dragoslav;
Zeltzer, Li‐at;
Brezinger, Karin;
Schachter, Jacob;
Nagler, Arnon;
Besser, Michal J.;
Toren, Amos

Publication type:

Article

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 6, p. 2703, doi. 10.1172/JCI62980

By:

Nemlich, Yael;
Greenberg, Eyal;
Ortenberg, Rona;
Besser, Michal J.;
Barshack, Iris;
Jacob-Hirsch, Jasmine;
Jacoby, Elad;
Eyal, Eran;
Rivkin, Ludmila;
Prieto, Victor G.;
Chakravarti, Nitin;
Duncan, Lyn M.;
Kallenberg, David M.;
Galun, Eitan;
Bennett, Dorothy C.;
Amariglio, Ninette;
Bar-Eli, Menashe;
Schachter, Jacob;
Rechavi, Gideon;
Markel, Gal

Publication type:

Article

Point-of-care CAR T-cell therapy as salvage strategy for out-of-specification tisagenlecleucel.

Published in:

Leukemia & Lymphoma, 2022, v. 63, n. 14, p. 3385, doi. 10.1080/10428194.2022.2123232

By:

Fried, Shalev;
Shouval, Roni;
Varda-Bloom, Nira;
Besser, Michal J.;
Yerushalmi, Ronit;
Shem-Tov, Noga;
Danylesko, Ivetta;
Jacoby, Elad;
Teihman, Shlomit;
Itzhaki, Orit;
Fein, Joshua A.;
Kedmi, Meirav;
Shimoni, Avichai;
Nagler, Arnon;
Avigdor, Abraham

Publication type:

Article

Characteristics and risk factors of infections following CD28-based CD19 CAR-T cells.

Published in:

Leukemia & Lymphoma, 2021, v. 62, n. 7, p. 1692, doi. 10.1080/10428194.2021.1881506

By:

Wittmann Dayagi, Talya;
Sherman, Gilad;
Bielorai, Bella;
Adam, Etai;
Besser, Michal J.;
Shimoni, Avichai;
Nagler, Arnon;
Toren, Amos;
Jacoby, Elad;
Avigdor, Abraham

Publication type:

Article

Tumor-infiltrating lymphocytes from human prostate tumors reveal anti-tumor reactivity and potential for adoptive cell therapy.

Published in:

OncoImmunology, 2019, v. 8, n. 12, p. 1, doi. 10.1080/2162402X.2019.1672494

By:

Yunger, Sharon;
Bar El, Assaf;
Zeltzer, Li-at;
Fridman, Eddie;
Raviv, Gil;
Laufer, Menachem;
Schachter, Jacob;
Markel, Gal;
Itzhaki, Orit;
Besser, Michal J

Publication type:

Article

Is there a future for adoptive cell transfer in melanoma patients?

Published in:

OncoImmunology, 2013, v. 2, n. 10, p. e26098-1, doi. 10.4161/onci.26098

By:

Besser, Michal J.

Publication type:

Article

TIL therapy broadens the tumor-reactive CD8<sup>+</sup> T cell compartment in melanoma patients.

Published in:

OncoImmunology, 2012, v. 1, n. 4, p. 409, doi. 10.4161/onci.18851

By:

Kvistborg, Pia;
Chengyi Jenny Shu;
Heemskerk, Bianca;
Fankhauser, Manuel;
Thrue, Charlotte Albæk;
Toebes, Mireille;
van Rooij, Nienke;
Linnemann, Carsten;
van Buuren, Marit M.;
Urbanus, Jos H. M.;
Beltman, Joost B.;
thor Straten, Per;
Li, Yong F.;
Robbins, Paul F.;
Besser, Michal J.;
Schachter, Jacob;
Kenter, Gemma G.;
Dudley, Mark E.;
Rosenberg, Steven A.;
Haanen, John B. A. G.

Publication type:

Article

R054: NK Cells Expansion and Activation for Cancer Immunotherapy

Published in:

2007

By:

Yakirevitch, Arkadi;
Zabari, Naama;
Schachter, Jacob;
Besser, Michal J.

Publication type:

Abstract

Novel Anti-Melanoma Immunotherapies: Disarming Tumor Escape Mechanisms.

Published in:

Clinical & Developmental Immunology, 2012, p. 1, doi. 10.1155/2012/818214

By:

Sapoznik, Sivan;
Hammer, Ohad;
Ortenberg, Rona;
Besser, Michal J.;
Ben-Moshe, Tehila;
Schachter, Jacob;
Markel, Gal

Publication type:

Article

Focus on Adoptive T Cell Transfer Trials in Melanoma.

Published in:

Clinical & Developmental Immunology, 2010, p. 1, doi. 10.1155/2010/260267

By:

Hershkovitz, Liat;
Schachter, Jacob;
Treves, Avraham J.;
Besser, Michal J.

Publication type:

Article

A comparative analysis of total serum miRNA profiles identifies novel signature that is highly indicative of metastatic melanoma: a pilot study.

Published in:

Biomarkers, 2013, v. 18, n. 6, p. 502, doi. 10.3109/1354750X.2013.816777

By:

Greenberg, Eyal;
Besser, Michal J.;
Ben-Ami, Eytan;
Shapira-Frommer, Ronnie;
Itzhaki, Orit;
Zikich, Dragoslav;
Levy, Daphna;
Kubi, Adva;
Eyal, Eran;
Onn, Amir;
Cohen, Yehudit;
Barshack, Iris;
Schachter, Jacob;
Markel, Gal

Publication type:

Article

microRNA expression patterns in tumor infiltrating lymphocytes are strongly associated with response to adoptive cell transfer therapy.

Published in:

Cancer Immunology, Immunotherapy, 2021, v. 70, n. 6, p. 1541, doi. 10.1007/s00262-020-02782-7

By:

Galore-Haskel, Gilli;
Greenberg, Eyal;
Yahav, Inbal;
Markovits, Ettai;
Ortenberg, Rona;
Shapira-Fromer, Ronnie;
Itzhaki, Orit;
Schachter, Jacob;
Besser, Michal J.;
Markel, Gal

Publication type:

Article

Reduced CTL motility and activity in avascular tumor areas.

Published in:

Cancer Immunology, Immunotherapy, 2019, v. 68, n. 8, p. 1287, doi. 10.1007/s00262-019-02361-5

By:

Manaster, Yoav;
Shipony, Zohar;
Hutzler, Anat;
Kolesnikov, Masha;
Avivi, Camila;
Shalmon, Bruria;
Barshack, Iris;
Besser, Michal J.;
Feferman, Tali;
Shakhar, Guy

Publication type:

Article

Establishment of adoptive cell therapy with tumor infiltrating lymphocytes for non-small cell lung cancer patients.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 8, p. 1221, doi. 10.1007/s00262-018-2174-4

By:

Ben-Avi, Ronny;
Farhi, Ronit;
Ben-Nun, Alon;
Gorodner, Marina;
Greenberg, Eyal;
Markel, Gal;
Schachter, Jacob;
Itzhaki, Orit;
Besser, Michal J.

Publication type:

Article

Systemic dysregulation of CEACAM1 in melanoma patients.

Published in:

Cancer Immunology, Immunotherapy, 2010, v. 59, n. 2, p. 215, doi. 10.1007/s00262-009-0740-5

By:

Markel, Gal;
Ortenberg, Rona;
Seidman, Rachel;
Sapoznik, Sivan;
Koren-Morag, Nira;
Besser, Michal J.;
Bar, Jair;
Shapira, Ronnie;
Kubi, Adva;
Nardini, Gil;
Tessone, Ariel;
Treves, Avraham J.;
Winkler, Eyal;
Orenstein, Arie;
Schachter, Jacob

Publication type:

Article

Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1116328

By:

Yunger, Sharon;
Geiger, Benjamin;
Friedman, Nir;
Besser, Michal J.;
Adutler-Lieber, Shimrit

Publication type:

Article

Impact of cryopreservation on CAR T production and clinical response.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.1024362

By:

Brezinger-Dayan, Karin;
Itzhaki, Orit;
Melnichenko, Jenny;
Kubi, Adva;
Zeltzer, Li-at;
Jacoby, Elad;
Avigdor, Abraham;
Frommer, Ronnie Shapira;
Besser, Michal J.

Publication type:

Article

The nuclear translocation of ERK1/2 as an anticancer target.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 6685, doi. 10.1038/ncomms7685

By:

Plotnikov, Alexander;
Flores, Karen;
Maik-Rachline, Galia;
Zehorai, Eldar;
Kapri-Pardes, Einat;
Berti, Denise A.;
Hanoch, Tamar;
Besser, Michal J.;
Seger, Rony

Publication type:

Article

Dynamic expression of protective CEACAM1 on melanoma cells during specific immune attack.

Published in:

Immunology, 2009, v. 126, n. 2, p. 186, doi. 10.1111/j.1365-2567.2008.02888.x

By:

Markel, Gal;
Seidman, Rachel;
Cohen, Yifat;
Besser, Michal J.;
Sinai, Tali Cohen;
Treves, Avraham J.;
Orenstein, Arie;
Berger, Raanan;
Schachter, Jacob

Publication type:

Article

Comprehensive single institute experience with melanoma TIL: Long term clinical results, toxicity profile, and prognostic factors of response.

Published in:

Molecular Carcinogenesis, 2020, v. 59, n. 7, p. 736, doi. 10.1002/mc.23193

By:

Besser, Michal J.;
Itzhaki, Orit;
Ben‐Betzalel, Guy;
Zippel, Douglas B.;
Zikich, Dragoslav;
Kubi, Adva;
Brezinger, Karin;
Nissani, Abraham;
Levi, Michal;
Zeltzer, Li‐at;
Ben‐Nun, Alon;
Asher, Nethanel;
Shimoni, Avichai;
Nagler, Arnon;
Markel, Gal;
Shapira‐Frommer, Ronnie;
Schachter, Jacob

Publication type:

Article

Genetic Modification of Tumor-Infiltrating Lymphocytes via Retroviral Transduction.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.584148

By:

Weinstein-Marom, Hadas;
Gross, Gideon;
Levi, Michal;
Brayer, Hadar;
Schachter, Jacob;
Itzhaki, Orit;
Besser, Michal J.

Publication type:

Article

Parameters of long‐term response with CD28‐based CD19 chimaeric antigen receptor‐modified T cells in children and young adults with B‐acute lymphoblastic leukaemia.

Published in:

British Journal of Haematology, 2022, v. 197, n. 4, p. 475, doi. 10.1111/bjh.18105

By:

Jacoby, Elad;
Bielorai, Bella;
Hutt, Daphna;
Itzhaki, Orit;
Adam, Etai;
Bar, Diana;
Besser, Michal J.;
Toren, Amos

Publication type:

Article

Predicting and controlling the reactivity of immune cell populations against cancer.

Published in:

Molecular Systems Biology, 2009, v. 5, n. 1, p. 265, doi. 10.1038/msb.2009.15

By:

Oved, Kfir;
Eden, Eran;
Akerman, Martin;
Noy, Roy;
Wolchinsky, Ron;
Izhaki, Orit;
Schallmach, Ester;
Kubi, Adva;
Zabari, Naama;
Schachter, Jacob;
Alon, Uri;
Mandel‐Gutfreund, Yael;
Besser, Michal J;
Reiter, Yoram

Publication type:

Article

Selection of Shared and Neoantigen-Reactive T Cells for Adoptive Cell Therapy Based on CD137 Separation.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01211

By:

Seliktar-Ofir, Sivan;
Merhavi-Shoham, Efrat;
Itzhaki, Orit;
Yunger, Sharon;
Markel, Gal;
Schachter, Jacob;
Besser, Michal J.

Publication type:

Article

Development of Allogeneic NK Cell Adoptive Transfer Therapy in Metastatic Melanoma Patients: In Vitro Preclinical Optimization Studies.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057922

By:

Besser, Michal J.;
Shoham, Tsipi;
Harari-Steinberg, Orit;
Zabari, Naama;
Ortenberg, Rona;
Yakirevitch, Arkadi;
Nagler, Arnon;
Loewenthal, Ron;
Schachter, Jacob;
Markel, Gal

Publication type:

Article

Nicotinamide Inhibits Vasculogenic Mimicry, an Alternative Vascularization Pathway Observed in Highly Aggressive Melanoma.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057160

By:

Itzhaki, Orit;
Greenberg, Eyal;
Shalmon, Bruria;
Kubi, Adva;
Treves, Avraham J.;
Shapira-Frommer, Ronnie;
Avivi, Camilla;
Ortenberg, Rona;
Ben-Ami, Eytan;
Schachter, Jacob;
Besser, Michal J.;
Markel, Gal

Publication type:

Article

Regulation of Cancer Aggressive Features in Melanoma Cells by MicroRNAs.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018936

By:

Greenberg, Eyal;
Hershkovitz, Liat;
Itzhaki, Orit;
Hajdu, Steven;
Nemlich, Yael;
Ortenberg, Rona;
Gefen, Nir;
Edry, Liat;
Modai, Shira;
Keisari, Yona;
Besser, Michal J.;
Schachter, Jacob;
Shomron, Noam;
Markel, Gal

Publication type:

Article

Natural Killer Lysis Receptor (NKLR)/NKLR-Ligand Matching as a Novel Approach for Enhancing Anti-Tumor Activity of Allogeneic NK Cells.

Published in:

PLoS ONE, 2009, v. 4, n. 5, p. 1, doi. 10.1371/journal.pone.0005597

By:

Markel, Gal;
Seidman, Rachel;
Besser, Michal J.;
Zabari, Naama;
Ortenberg, Rona;
Shapira, Ronnie;
Treves, Avraham J.;
Loewenthal, Ron;
Orenstein, Arie;
Nagler, Arnon;
Schachter, Jacob

Publication type:

Article

Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia.

Published in:

Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01347

By:

Rozenbaum, Meir;
Meir, Amilia;
Aharony, Yarden;
Itzhaki, Orit;
Schachter, Jacob;
Bank, Ilan;
Jacoby, Elad;
Besser, Michal J.

Publication type:

Article

Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes.

Published in:

Science Translational Medicine, 2022, v. 14, n. 676, p. 1, doi. 10.1126/scitranslmed.abo3724

By:

Jacoby, Elad;
Bar-Yosef, Omer;
Gruber, Noah;
Lahav, Einat;
Varda-Bloom, Nira;
Bolkier, Yoav;
Bar, Diana;
Blumkin, Moriya Ben-Yakir;
Barak, Sharon;
Eisenstein, Etzyona;
Ahonniska-Assa, Jaana;
Silberg, Tamar;
Krasovsky, Tal;
Bar, Orly;
Erez, Neta;
Bielorai, Bella;
Golan, Hana;
Dekel, Benjamin;
Besser, Michal J.;
Pozner, Gat

Publication type:

Article