Works by Bertilsson, Leif

Results: 98

Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin.

Published in:

European Journal of Clinical Pharmacology, 2018, v. 74, n. 11, p. 1405, doi. 10.1007/s00228-018-2499-0

By:

Mugusi, Sabina;
Ngaimisi, Eliford;
Janabi, Mohammed;
Mugusi, Ferdinand;
Minzi, Omary;
Aris, Eric;
Bakari, Muhammad;
Bertilsson, Leif;
Burhenne, Juergen;
Sandstrom, Eric;
Aklillu, Eleni

Publication type:

Article

N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.

Published in:

European Journal of Clinical Pharmacology, 2018, v. 74, n. 7, p. 903, doi. 10.1007/s00228-018-2448-y

By:

Aklillu, Eleni;
Carrillo, Juan Antonio;
Makonnen, Eyasu;
Bertilsson, Leif;
Djordjevic, Natasa

Publication type:

Article

Lower CYP2C9 activity in Turkish patients with Behçet's disease compared to healthy subjects: a down-regulation due to inflammation?

Published in:

European Journal of Clinical Pharmacology, 2015, v. 71, n. 10, p. 1223, doi. 10.1007/s00228-015-1899-7

By:

Goktaş, Mustafa;
Hatta, Fazleen;
Karaca, Ozgur;
Kalkisim, Said;
Kilic, Levent;
Akdogan, Ali;
Babaoglu, Melih;
Bozkurt, Atilla;
Helldén, Anders;
Bertilsson, Leif;
Yasar, Umit

Publication type:

Article

Risperidone metabolic ratio as a biomarker of individual CYP2D6 genotype in schizophrenic patients.

Published in:

European Journal of Clinical Pharmacology, 2014, v. 70, n. 6, p. 695, doi. 10.1007/s00228-014-1664-3

By:

Mannheimer, Buster;
Holm, Johan;
Koukel, Larissa;
Bertilsson, Leif;
Ösby, Urban;
Eliasson, Erik

Publication type:

Article

Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 7, p. 1033, doi. 10.1007/s00228-012-1210-0

By:

Hatta, Fazleen;
Teh, Lay;
Helldén, Anders;
Hellgren, Karin;
Roh, Hyung-Keun;
Salleh, Mohd;
Aklillu, Eleni;
Bertilsson, Leif

Publication type:

Article

Metabolism of alprazolam (a marker of CYP3A4) in hemodialysis patients with persistent inflammation.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 5, p. 571, doi. 10.1007/s00228-011-1163-8

By:

Molanaei, Hadi;
Stenvinkel, Peter;
Qureshi, Abdul;
Carrero, Juan;
Heimbürger, Olof;
Lindholm, Bengt;
Diczfalusy, Ulf;
Odar-Cederlöf, Ingegerd;
Bertilsson, Leif

Publication type:

Article

Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol.

Published in:

2011

By:

Nylén, Hanna;
Sergel, Sofia;
Forsberg, Lisa;
Lindemalm, Synnöve;
Bertilsson, Leif;
Wide, Katarina;
Diczfalusy, Ulf

Publication type:

Journal Article

Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol.

Published in:

European Journal of Clinical Pharmacology, 2011, v. 67, n. 7, p. 715, doi. 10.1007/s00228-010-0984-1

By:

Nylén, Hanna;
Sergel, Sofia;
Forsberg, Lisa;
Lindemalm, Synnöve;
Bertilsson, Leif;
Wide, Katarina;
Diczfalusy, Ulf

Publication type:

Article

CYP2C19 activity comparison between Swedes and Koreans: effect of genotype, sex, oral contraceptive use, and smoking.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 9, p. 871, doi. 10.1007/s00228-010-0835-0

By:

Ramsjö, Margareta;
Aklillu, Eleni;
Bohman, Lilleba;
Ingelman-Sundberg, Magnus;
Roh, Hyung-Keun;
Bertilsson, Leif

Publication type:

Article

Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.

Published in:

2010

By:

Helldén, Anders;
Bergman, Ulf;
Engström Hellgren, Karin;
Masquelier, Michèle;
Nilsson Remahl, Ingela;
Odar-Cederlöf, Ingegerd;
Ramsjö, Margareta;
Bertilsson, Leif

Publication type:

Case Study

Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure—an impact similar to male gender or smoking in schizophrenic patients.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 5, p. 465, doi. 10.1007/s00228-009-0783-8

By:

Ghotbi, Roza;
Mannheimer, Buster;
Aklillu, Eleni;
Suda, Akira;
Bertilsson, Leif;
Eliasson, Erik;
Ösby, Urban

Publication type:

Article

Influence of the CYP2D6 polymorphism and hemodialysis on codeine disposition in patients with end-stage renal disease.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 269, doi. 10.1007/s00228-009-0759-8

By:

Molanaei, Hadi;
Carrero, Juan;
Heimbürger, Olof;
Nordfors, Louise;
Lindholm, Bengt;
Stenvinkel, Peter;
Odar-Cederlöf, Ingegerd;
Bertilsson, Leif

Publication type:

Article

Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 12, p. 1175, doi. 10.1007/s00228-008-0529-z

By:

Rosenborg, Staffan Ohlsson;
Mwinyi, Jessica;
Andersson, Maria;
Baldwin, R. Michael;
Pedersen, Rasmus Steen;
Sim, Sarah C.;
Bertilsson, Leif;
Ingelman-Sundberg, Magnus;
Eliasson, Erik

Publication type:

Article

CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 12, p. 1163, doi. 10.1007/s00228-008-0525-3

By:

Goryachkina, Ksenia;
Burbello, Aleksandra;
Boldueva, Svetlana;
Babak, Svetlana;
Bergman, Ulf;
Bertilsson, Leif

Publication type:

Article

Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 4, p. 381, doi. 10.1007/s00228-007-0438-6

By:

Djordjevic, Natasa;
Ghotbi, Roza;
Bertilsson, Leif;
Jankovic, Slobodan;
Aklillu, Eleni

Publication type:

Article

Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI).

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 3, p. 275, doi. 10.1007/s00228-007-0404-3

By:

Goryachkina, Ksenia;
Burbello, Aleksandra;
Boldueva, Svetlana;
Babak, Svetlana;
Bergman, Ulf;
Bertilsson, Leif

Publication type:

Article

Voriconazole and fluconazole increase the exposure to oral diazepam.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 10, p. 941, doi. 10.1007/s00228-007-0350-0

By:

Saari, Teijo I.;
Laine, Kari;
Bertilsson, Leif;
Neuvonen, Pertti J.;
Olkkola, Klaus T.

Publication type:

Article

Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 6, p. 537, doi. 10.1007/s00228-007-0288-2

By:

Ghotbi, Roza;
Christensen, Magnus;
Hyung-Keun Roh;
Ingelman-Sundberg, Magnus;
Aklillu, Eleni;
Bertilsson, Leif

Publication type:

Article

Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 2, p. 173, doi. 10.1007/s00228-006-0230-z

By:

Allqvist, Annika;
Miura, Jun;
Bertilsson, Leif;
Mirghani, Rajaa

Publication type:

Article

Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 7, p. 539, doi. 10.1007/s00228-006-0121-3

By:

Wennerholm, Agneta;
Nordmark, Anna;
Pihlsgård, Maria;
Mahindi, Margarita;
Bertilsson, Leif;
Gustafsson, Lars L.

Publication type:

Article

Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of a- and 4-hydroxy metabolites in healthy subjects.

Published in:

European Journal of Clinical Pharmacology, 2005, v. 61, n. 2, p. 113, doi. 10.1007/s00228-004-0861-x

By:

Wennerholm, Agneta;
Allqvist, Annika;
Svensson, Jan-Olof;
Gustafsson, Lars;
Mirghani, Rajaa;
Bertilsson, Leif

Publication type:

Article

Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study.

Published in:

European Journal of Clinical Pharmacology, 2004, v. 59, n. 11, p. 803, doi. 10.1007/s00228-003-0701-4

By:

Kawanishi, Chiaki;
Lundgren, Stefan;
Ågren, Hans;
Bertilsson, Leif

Publication type:

Article

Xanthine oxidase activity is influenced by environmental factors in Ethiopians.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 7, p. 533, doi. 10.1007/s00228-003-0653-8

By:

Aklillu, Eleni;
Carrillo, Juan Antonio;
Makonnen, Eyasu;
Bertilsson, Leif;
Ingelman-Sundberg, Magnus

Publication type:

Article

Metabolism and elimination of quinine in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 5/6, p. 423, doi. 10.1007/s00228-003-0637-8

By:

Mirghani, Rajaa A.;
Hellgren, Urban;
Bertilsson, Leif;
Gustafsson, Lars L.;
Ericsson, Örjan

Publication type:

Article

Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 1, p. 23, doi. 10.1007/s00228-003-0575-5

By:

Mirghani, Rajaa A.;
Ericsson, Örjan;
Tybring, Gunnel;
Gustafsson, Lars L.;
Bertilsson, Leif

Publication type:

Article

Intraindividual Similarity in the Metabolism of Amitriptyline and Chlorimipramine in Depressed Patients.

Published in:

Pharmacology, 1979, v. 19, n. 5, p. 282, doi. 10.1159/000137324

By:

Mellström, Britt;
Bertilsson, Leif;
Träskman, Lil;
Rollins, Douglas;
Åsberg, Marie;
Sjöqvist, Folke

Publication type:

Article

Decreased Activity and Genetic Polymorphisms of CYP2C19 in Behçet's Disease.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2017, v. 121, n. 4, p. 266, doi. 10.1111/bcpt.12710

By:

Goktas, Mustafa Tugrul;
Karaca, Ragip Ozgur;
Kalkisim, Said;
Cevik, Lokman;
Kilic, Levent;
Akdogan, Ali;
Babaoglu, Melih O.;
Bozkurt, Atilla;
Bertilsson, Leif;
Yasar, Umit

Publication type:

Article

Plasma Levels of 25-Hydroxyvitamin D3 and In Vivo Markers of Cytochrome P450 3 A Activity in Swedes and Koreans: Effects of a Genetic Polymorphism and Oral Contraceptives.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 115, n. 4, p. 366, doi. 10.1111/bcpt.12230

By:

Nylén, Hanna;
Björkhem‐Bergman, Linda;
Ekström, Lena;
Roh, Hyung‐Keun;
Bertilsson, Leif;
Eliasson, Erik;
Lindh, Jonatan D.;
Diczfalusy, Ulf

Publication type:

Article

Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34674-3

By:

Kitabi, Eliford Ngaimisi;
Minzi, Omary Mashiku Sylivester;
Mugusi, Sabina;
Sasi, Philip;
Janabi, Mohamed;
Mugusi, Ferdinand;
Bertilsson, Leif;
Burhenne, Jürgen;
Aklillu, Eleni

Publication type:

Article

Detection of N-Terminally Extended Substance P but Not of Substance P in Human Cerebrospinal Fluid: Quantitation with HPLC-Radioimmunoassay.

Published in:

Journal of Neurochemistry, 1988, v. 50, n. 6, p. 1701, doi. 10.1111/j.1471-4159.1988.tb02466.x

By:

Toresson, Gudrun;
Brodin, Ernst;
Wahlström, Agneta;
Bertilsson, Leif

Publication type:

Article

Importance of Ethnicity, CYP2B6 and ABCB1 Genotype for Efavirenz Pharmacokinetics and Treatment Outcomes: A Parallel-Group Prospective Cohort Study in Two Sub-Saharan Africa Populations.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0067946

By:

Ngaimisi, Eliford;
Habtewold, Abiy;
Minzi, Omary;
Makonnen, Eyasu;
Mugusi, Sabina;
Amogne, Wondwossen;
Yimer, Getnet;
Riedel, Klaus-Dieter;
Janabi, Mohammed;
Aderaye, Getachew;
Mugusi, Ferdinand;
Bertilsson, Leif;
Aklillu, Eleni;
Burhenne, Juergen

Publication type:

Article

Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1538, doi. 10.1002/jcph.756

By:

Habtewold, Abiy;
Aklillu, Eleni;
Makonnen, Eyasu;
Amogne, Wondwossen;
Yimer, Getnet;
Aderaye, Getachew;
Bertilsson, Leif;
Owen, Joel S.;
Burhenne, Jürgen

Publication type:

Article

Comparison of N-Acetyltransferase-2 Enzyme Genotype-Phenotype and Xanthine Oxidase Enzyme Activity Between Swedes and Koreans.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1527, doi. 10.1177/0091270011420261

By:

Djordjevic, Natasa;
Carrillo, Juan Antonio;
Roh, Hyung-Keun;
Karlsson, Sara;
Ueda, Nobuhisa;
Bertilsson, Leif;
Aklillu, Eleni

Publication type:

Article

Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients.

Published in:

European Journal of Clinical Pharmacology, 2001, v. 57, n. 9, p. 671, doi. 10.1007/s002280100372

By:

Roh, Hyung-Keun;
Kim, Chul-Eung;
Chung, Woon-Gye;
Park, Chang-Shin;
Svensson, Jan-Olof;
Bertilsson, Leif

Publication type:

Article

CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline.

Published in:

European Journal of Clinical Pharmacology, 2001, v. 57, n. 2, p. 137, doi. 10.1007/s002280100289

By:

Laine, Kari;
Anttila, Markku;
Nyman, Leena;
Wahlberg, Anneli;
Bertilsson, Leif

Publication type:

Article

Monoamine Metabolites Level in CSF is Related to the 5-HTT Gene Polymorphism in Treatment-Resistant Depression.

Published in:

Neuropsychopharmacology, 2007, v. 32, n. 10, p. 2143, doi. 10.1038/sj.npp.1301336

By:

Kishida, Ikuko;
Aklillu, Eleni;
Kawanishi, Chiaki;
Bertilsson, Leif;
Ågren, Hans

Publication type:

Article

Significance of monitoring plasma levels of amitriptyline, and its hydroxylated and desmethylated metabolites in prediction of the clinical outcome of depressive state.

Published in:

Psychiatry & Clinical Neurosciences, 1997, v. 51, n. 1, p. 35, doi. 10.1111/j.1440-1819.1997.tb02364.x

By:

SHIMODA, KAZUTAKA;
YASUDA, SHIN;
MORITA, SACHIYO;
SHIBASAKI, MORIKAZU;
SOMEYA, TOSHIYUKI;
BERTILSSON, LEIF;
MD, SABURO TAKAHASHI

Publication type:

Article

Tribute to Folke Sjöqvist, a Pioneer in Clinical Pharmacology.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 6, p. 1127, doi. 10.1002/cpt.1935

By:

Dahl, Marja‐Liisa;
Bergman, Ulf;
Bertilsson, Leif;
Eliasson, Erik;
Gustafsson, Lars L.;
Panagiotidis, Georgios;
Rane, Anders

Publication type:

Article

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants*.

Published in:

Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 1, p. 103, doi. 10.1016/j.clpt.2005.10.002

By:

Sim, Sarah C.;
Risinger, Carl;
Dahl, Marja-Liisa;
Aklillu, Eleni;
Christensen, Magnus;
Bertilsson, Leif;
Ingelman-Sundberg, Magnus

Publication type:

Article

The karolinska cocktail for phenotyping of five human cytochrome P450 enzymes*.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 6, p. 517, doi. 10.1016/S0009-9236(03)00050-X

By:

Christensen, Magnus;
Andersson, Katarina;
Dalén, Per;
Mirghani, Rajaa A.;
Muirhead, Gary J.;
Nordmark, Anna;
Tybring, Gunnel;
Wahlberg, Anneli;
Yaşar, Ümit;
Bertilsson, Leif

Publication type:

Article

Low daily 10-mg and 20-mg doses of fluvoxamine inhibit the metabolism of both caffeine (cytochrome P4501A2) and omeprazole (cytochrome P4502C19)*.

Published in:

Clinical Pharmacology & Therapeutics, 2002, v. 71, n. 3, p. 141, doi. 10.1067/mcp.2002.121788

By:

Christensen, Magnus;
Tybring, Gunnel;
Mihara, Kazuo;
Yasui-Furokori, Norio;
Carrillo, Juan Antonio;
Ramos, Sara I.;
Andersson, Katarina;
Dahl, Marja-Liisa;
Bertilsson, Leif

Publication type:

Article

The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity.

Published in:

Clinical Pharmacology & Therapeutics, 2002, v. 71, n. 1, p. 77, doi. 10.1067/mcp.2002.120239

By:

Wennerholm, Agneta;
Dandara, Collet;
Sayi, Jane;
Svensson, Jan-Olov;
Abdi, Yakoub Aden;
Ingelman-Sundberg, Magnus;
Bertilsson, Leif;
Hasler, Julia;
Gustafsson, Lars L.

Publication type:

Article

Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test*.

Published in:

Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 4, p. 327, doi. 10.1016/S0009-9236(01)78384-1

By:

Laine, Kari;
Tybring, Gunnel;
Härtter, Sebastian;
Andersson RN, Katarina;
Svensson, Jan-Olof;
Widén, Jolanta;
Bertilsson, Leif

Publication type:

Article

Orally given melatonin may serve as a probe drug for cytochrome P450 1A2 activity in vivo: A pilot study*.

Published in:

Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 1, p. 10, doi. 10.1067/mcp.2001.116512

By:

Härtter, Sebastian;
Ursing, Carina;
Morita, Sachiyo;
Tybring, Gunnel;
von Bahr, Christer;
Christensen, Magnus;
Röjdmark, Sven;
Bertilsson, Leif

Publication type:

Article

No sex-related differences but significant inhibition by oral contraceptives of CYP2C19 activity as measured by the probe drugs mephenytoin and omeprazole in healthy Swedish white subjects*.

Published in:

Clinical Pharmacology & Therapeutics, 2000, v. 68, n. 2, p. 151, doi. 10.1067/mcp.2000.108949

By:

Laine, Kari;
Tybring, Gunnel;
Bertilsson, Leif

Publication type:

Article

Slow chloroguanide metabolism in Tanzanians compared with white subjects and Asian subjects confirms a decreased CYP2C19 activity in relation to genotype*.

Published in:

Clinical Pharmacology & Therapeutics, 2000, v. 68, n. 2, p. 189, doi. 10.1067/mcp.2000.108583

By:

Herrlin, Karin;
Massele, Amos Y.;
Rimoy, Gerard;
Alm, Christina;
Rais, Margareta;
Ericsson, Örjan;
Bertilsson, Leif;
Gustafsson, Lars L.

Publication type:

Article

The roles of cytochrome P450 3A4 and lA2 in the 3-hydroxylation of quinine in vivo*.

Published in:

Clinical Pharmacology & Therapeutics, 1999, v. 66, n. 5, p. 454, doi. 10.1016/S0009-9236(99)70008-1

By:

Mirghani, Rajaa A.;
Hellgren, Urban;
Westerberg, Per Anton;
Ericsson, Orjan;
Bertilsson, Leif;
Gustafsson, Lars L.

Publication type:

Article

Metabolism of ropivacaine in humans is mediated by CYP1A2 and to a minor extent by CYP3A4: An interaction study with fluvoxamine and ketoconazole as in vivo inhibitors*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 5, p. 484, doi. 10.1016/S0009-9236(98)90131-X

By:

Arlander, Eva;
Ekström, Gunilla;
Alm, Christina;
Carrillo, Juan Antonio;
Bielenstein, Margareta;
Böttiger, Ylva;
Bertilsson, Leif;
Gustafsson, Lars L.

Publication type:

Article

Pharmacokinetics of nortriptyline and its 10-hydroxy metabolite in Chinese subjects of different CYP2D6 genotypes*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 4, p. 384, doi. 10.1016/S0009-9236(98)90069-8

By:

Yue, Qun-Ying;
Zhong, Zhi-Hui;
Tybring, Gunnel;
Dalén, Per;
Dahl, Marja-Liisa;
Bertilsson, Leif;
Sjöqvist, Folke

Publication type:

Article

Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 4, p. 391, doi. 10.1016/S0009-9236(98)90070-4

By:

Herrlin, Karin;
Massele, Amos Y.;
Jande, Mary;
Alm, Christina;
Tybring, Gunnel;
Abdi, Yakoub Aden;
Wennerholm, Agneta;
Johansson, Inger;
Dahl, Marja-Liisa;
Bertilsson, Leif;
Gustafsson, Lars L.

Publication type:

Article