Works by Bergsagel, P. Leif

Results: 48

Inflation of tumor mutation burden by tumor-only sequencing in under-represented groups.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00164-5

By:

Asmann, Yan W.;
Parikh, Kaushal;
Bergsagel, P. Leif;
Dong, Haidong;
Adjei, Alex A.;
Borad, Mitesh J.;
Mansfield, Aaron S.

Publication type:

Article

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.

Published in:

EMBO Journal, 2015, v. 34, n. 9, p. 1214, doi. 10.15252/embj.201489920

By:

Desantis, Agata;
Bruno, Tiziana;
Catena, Valeria;
De Nicola, Francesca;
Goeman, Frauke;
Iezzi, Simona;
Sorino, Cristina;
Ponzoni, Maurilio;
Bossi, Gianluca;
Federico, Vincenzo;
La Rosa, Francesca;
Ricciardi, Maria Rosaria;
Lesma, Elena;
De Meo, Paolo D'Onorio;
Castrignanò, Tiziana;
Petrucci, Maria Teresa;
Pisani, Francesco;
Chesi, Marta;
Bergsagel, P Leif;
Floridi, Aristide

Publication type:

Article

Correction: Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients.

Published in:

2023

By:

Fonseca, Rodrigo;
Arribas, Mariano;
Wiedmeier-Nutor, Julia E.;
Kusne, Yael N.;
González Vélez, Miguel;
Kosiorek, Heidi E.;
Butterfield, Richard J.;
Kirsch, Ilan R.;
Mikhael, Joseph R.;
Stewart, A. Keith;
Reeder, Craig;
Larsen, Jeremy;
Bergsagel, P. Leif;
Fonseca, Rafael

Publication type:

Correction Notice

Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma.

Published in:

Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00851-5

By:

Baughn, Linda B.;
Jessen, Erik;
Sharma, Neeraj;
Tang, Hongwei;
Smadbeck, James B.;
Long, Mark D.;
Pearce, Kathryn;
Smith, Matthew;
Dasari, Surendra;
Sachs, Zohar;
Linden, Michael A.;
Cook, Joselle;
Keith Stewart, A.;
Chesi, Marta;
Mitra, Amit;
Leif Bergsagel, P.;
Van Ness, Brian;
Kumar, Shaji K.

Publication type:

Article

Prognostic value of early bone marrow MRD status in CAR-T therapy for myeloma.

Published in:

Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00820-y

By:

Bansal, Radhika;
Baksh, Mizba;
Larsen, Jeremy T.;
Hathcock, Matthew A.;
Dingli, David;
Stewart, A. Keith;
Kapoor, Prashant;
Kourelis, Taxiarchis;
Hayman, Suzanne R.;
Warsame, Rahma M.;
Fonseca, Rafael;
Bergsagel, P. Leif;
Ailawadhi, Sikander;
Kumar, Shaji K.;
Lin, Yi

Publication type:

Article

Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients.

Published in:

Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00794-x

By:

Fonseca, Rodrigo;
Arribas, Mariano;
Wiedmeier-Nutor, Julia E.;
Kusne, Yael N.;
González Vélez, Miguel;
Kosiorek, Heidi E.;
Butterfield, Richard J.;
Kirsch, Ilan R.;
Mikhael, Joseph R.;
Stewart, A. Keith;
Reeder, Craig;
Larsen, Jeremy;
Bergsagel, P. Leif;
Fonseca, Rafael

Publication type:

Article

Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma.

Published in:

Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00851-5

By:

Baughn, Linda B.;
Jessen, Erik;
Sharma, Neeraj;
Tang, Hongwei;
Smadbeck, James B.;
Long, Mark D.;
Pearce, Kathryn;
Smith, Matthew;
Dasari, Surendra;
Sachs, Zohar;
Linden, Michael A.;
Cook, Joselle;
Keith Stewart, A.;
Chesi, Marta;
Mitra, Amit;
Leif Bergsagel, P.;
Van Ness, Brian;
Kumar, Shaji K.

Publication type:

Article

Prognostic value of early bone marrow MRD status in CAR-T therapy for myeloma.

Published in:

Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00820-y

By:

Bansal, Radhika;
Baksh, Mizba;
Larsen, Jeremy T.;
Hathcock, Matthew A.;
Dingli, David;
Stewart, A. Keith;
Kapoor, Prashant;
Kourelis, Taxiarchis;
Hayman, Suzanne R.;
Warsame, Rahma M.;
Fonseca, Rafael;
Bergsagel, P. Leif;
Ailawadhi, Sikander;
Kumar, Shaji K.;
Lin, Yi

Publication type:

Article

Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients.

Published in:

Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00794-x

By:

Fonseca, Rodrigo;
Arribas, Mariano;
Wiedmeier-Nutor, Julia E.;
Kusne, Yael N.;
González Vélez, Miguel;
Kosiorek, Heidi E.;
Butterfield, Richard J.;
Kirsch, Ilan R.;
Mikhael, Joseph R.;
Stewart, A. Keith;
Reeder, Craig;
Larsen, Jeremy;
Bergsagel, P. Leif;
Fonseca, Rafael

Publication type:

Article

Distribution of clonal hematopoiesis of indeterminate potential (CHIP) is not associated with race in patients with plasma cell neoplasms.

Published in:

2022

By:

Gagnon, Marie-France;
Tian, Shulan;
Geyer, Susan;
Sharma, Neeraj;
Vachon, Celine M.;
Kusne, Yael;
Bergsagel, P. Leif;
Stewart, A. Keith;
Rajkumar, S. Vincent;
Kumar, Shaji;
Ailawadhi, Sikander;
Baughn, Linda B.

Publication type:

Letter

The CCND1 c.870G risk allele is enriched in individuals of African ancestry with plasma cell dyscrasias.

Published in:

2020

By:

Baughn, Linda B.;
Li, Zhuo;
Pearce, Kathryn;
Vachon, Celine M.;
Polley, Mei-Yin;
Keats, Jonathan;
Elhaik, Eran;
Baird, Michael;
Therneau, Terry;
Cerhan, James R.;
Bergsagel, P. Leif;
Dispenzieri, Angela;
Rajkumar, S. Vincent;
Asmann, Yan W.;
Kumar, Shaji

Publication type:

Letter

Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma.

Published in:

Blood Cancer Journal, 2019, v. 9, n. 12, p. 1, doi. 10.1038/s41408-019-0255-z

By:

Smadbeck, James;
Peterson, Jess F.;
Pearce, Kathryn E.;
Pitel, Beth A.;
Figueroa, Andrea Lebron;
Timm, Michael;
Jevremovic, A. Dragan;
Shi, Min;
Stewart, A. Keith;
Braggio, Esteban;
Riggs, Daniel L.;
Bergsagel, P. Leif;
Vasmatzis, George;
Kearney, Hutton M.;
Hoppman, Nicole L.;
Ketterling, Rhett P.;
Kumar, Shaji;
Rajkumar, S. Vincent;
Greipp, Patricia T.;
Baughn, Linda B.

Publication type:

Article

Polyclonal serum free light chain elevation is associated with increased risk of monoclonal gammopathies.

Published in:

Blood Cancer Journal, 2019, v. 9, n. 6, p. N.PAG, doi. 10.1038/s41408-019-0210-z

By:

Kumar, Shaji;
Larson, Dirk R.;
Dispenzieri, Angela;
Therneau, Terry M.;
Murray, David L.;
Leif Bergsagel, P.;
Kyle, Robert A.;
Vincent Rajkumar, S.

Publication type:

Article

Phase II trial of nab-paclitaxel in patients with relapsed or refractory multiple myeloma.

Published in:

American Journal of Hematology, 2016, v. 91, n. 12, p. E504, doi. 10.1002/ajh.24548

By:

Jain, Tania;
Dueck, Amylou C.;
Kosiorek, Heidi e.;
Ginos, Brenda F.;
Mayo, Angela;
Reeder, Craig B.;
Chesi, Marta;
Mikhael, Joseph;
Keith Stewart, A.;
Leif Bergsagel, P.;
Fonseca, Rafael

Publication type:

Article

Long-term results of the phase II trial of the oral mTOR inhibitor everolimus (RAD001) in relapsed or refractory Waldenstrom Macroglobulinemia.

Published in:

American Journal of Hematology, 2014, v. 89, n. 3, p. 237, doi. 10.1002/ajh.23620

By:

Ghobrial, Irene M.;
Witzig, Thomas E.;
Gertz, Morie;
LaPlant, Betsy;
Hayman, Suzanne;
Camoriano, John;
Lacy, Martha;
Bergsagel, P. Leif;
Chuma, Stacey;
DeAngelo, Daniel;
Treon, Steven P.

Publication type:

Article

Lenalidomide, cyclophosphamide and dexamethasone (CRd) for newly diagnosed multiple myeloma: Results from a phase 2 trial.

Published in:

American Journal of Hematology, 2011, v. 86, n. 8, p. 640, doi. 10.1002/ajh.22053

By:

Kumar, Shaji K.;
Lacy, Martha Q.;
Hayman, Suzanne R.;
Stewart, Keith;
Buadi, Francis K.;
Allred, Jacob;
Laumann, Kristina;
Greipp, Philip R.;
Lust, John A.;
Gertz, Morie A.;
Zeldenrust, Steven R.;
Bergsagel, P. Leif;
Reeder, Craig B.;
Witzig, Thomas E.;
Fonseca, Rafael;
Russell, Stephen J.;
Mikhael, Joseph R.;
Dingli, David;
Rajkumar, S. Vincent;
Dispenzieri, Angela

Publication type:

Article

Initial genome sequencing and analysis of multiple myeloma.

Published in:

Nature, 2011, v. 471, n. 7339, p. 467, doi. 10.1038/nature09837

By:

Chapman, Michael A.;
Lawrence, Michael S.;
Keats, Jonathan J.;
Cibulskis, Kristian;
Sougnez, Carrie;
Schinzel, Anna C.;
Harview, Christina L.;
Brunet, Jean-Philippe;
Ahmann, Gregory J.;
Adli, Mazhar;
Anderson, Kenneth C.;
Ardlie, Kristin G.;
Auclair, Daniel;
Baker, Angela;
Bergsagel, P. Leif;
Bernstein, Bradley E.;
Drier, Yotam;
Fonseca, Rafael;
Gabriel, Stacey B.;
Hofmeister, Craig C.

Publication type:

Article

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.

Published in:

Nature, 2011, v. 470, n. 7332, p. 124, doi. 10.1038/nature09658

By:

Huadong Pei;
Lindsey Zhang;
Kuntian Luo;
Yuxin Qin;
Chesi, Marta;
Fei, Frances;
Bergsagel, P. Leif;
Liewei Wang;
Zhongsheng You;
Zhenkun Lou

Publication type:

Article

Venetoclax-based treatment combinations in relapsed/refractory multiple myeloma: practice patterns and impact of secondary cytogenetic abnormalities on outcomes.

Published in:

Blood Cancer Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41408-025-01264-2

By:

Bolarinwa, Abiola;
Nagaraj, Madhu;
Zanwar, Saurabh;
Abdallah, Nadine;
Bergsagel, P. Leif;
Binder, Moritz;
Buadi, Francis;
Chhabra, Saurabh;
Cook, Joselle;
Dingli, David;
Dispenzieri, Angela;
Gertz, Morie A.;
Gonsalves, Wilson;
Hayman, Suzanne;
Kapoor, Prashant;
Kourelis, Taxiarchis;
Leung, Nelson;
Lin, Yi;
Muchtar, Eli;
Parrondo, Ricardo

Publication type:

Article

Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention.

Published in:

Blood Cancer Journal, 2025, v. 14, n. 1, p. 1, doi. 10.1038/s41408-025-01215-x

By:

Fonseca, Rodrigo;
Zhu, Yuan Xiao;
Bruins, Laura A.;
Ahmann, Joseph;
de Bonolo Campos, Cecilia;
Braggio, Esteban;
Chen, Xianfeng;
Arribas, Mariano;
Darvish, Susie;
Welsh, Seth;
Meermeier, Erin;
Mangalaparthi, Kiran K.;
Kandasamy, Richard K.;
Ahmann, Greg;
Wiedmeier-Nutor, J. Erin;
Pandey, Akhilesh;
Chesi, Marta;
Bergsagel, P. Leif;
Fonseca, Rafael

Publication type:

Article

Chromosome translocations in multiple myeloma.

Published in:

Oncogene, 2001, v. 20, n. 40, p. 5611, doi. 10.1038/sj.onc.1204641

By:

Bergsagel, P Leif;
Kuehl, W Michael

Publication type:

Article

Response to COVID-19 Vaccination Post-CAR T Therapy in Patients With Non-Hodgkin Lymphoma and Multiple Myeloma.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2023, v. 23, n. 6, p. 456, doi. 10.1016/j.clml.2023.03.002

By:

Wiedmeier-Nutor, Julia E.;
Iqbal, Madiha;
Rosenthal, Allison C.;
Bezerra, Evandro D.;
Garcia-Robledo, Juan Esteban;
Bansal, Radhika;
Johnston, Patrick B.;
Hathcock, Matthew;
Larsen, Jeremy T.;
Leif Bergsagel, P.;
Wang, Yucai;
Reeder, Craig B.;
Leis, Jose F.;
Fonseca, Rafael;
Palmer, Jeanne M.;
Gysbers, Brianna J.;
Mwangi, Raphael;
Warsame, Rahma M.;
Kourelis, Taxiarchis;
Hayman, Suzanne R.

Publication type:

Article

Evaluation of Revised International Staging System (R-ISS) for transplant-eligible multiple myeloma patients.

Published in:

2018

By:

González-Calle, Verónica;
Slack, Abigail;
Keane, Niamh;
Luft, Susan;
Pearce, Kathryn E.;
Ketterling, Rhett P.;
Jain, Tania;
Chirackal, Sintosebastian;
Reeder, Craig;
Mikhael, Joseph;
Noel, Pierre;
Mayo, Angela;
Adams, Roberta H.;
Ahmann, Gregory;
Braggio, Esteban;
Stewart, A. Keith;
Bergsagel, P. Leif;
Van Wier, Scott A.;
Fonseca, Rafael

Publication type:

journal article

V. Molecular classification and risk stratification of myeloma.

Published in:

Hematological Oncology, 2013, v. 31, p. 38, doi. 10.1002/hon.2065

By:

Bergsagel, P. Leif;
Chesi, Marta

Publication type:

Article

Osteopontin dysregulation and lytic bone lesions in multiple myeloma.

Published in:

Hematological Oncology, 2007, v. 25, n. 1, p. 16, doi. 10.1002/hon.803

By:

Robbiani, Davide F.;
Colon, Kaity;
Ely, Sarah;
Ely, Scott;
Chesi, Marta;
Bergsagel, P. Leif

Publication type:

Article

MULTIPLE MYELOMA: EVOLVING GENETIC EVENTS AND HOST INTERACTIONS.

Published in:

Nature Reviews Cancer, 2002, v. 2, n. 3, p. 175, doi. 10.1038/nrc746

By:

Kuehl, W. Michael;
Bergsagel, P. Leif

Publication type:

Article

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07305-8

By:

Calcinotto, Arianna;
Brevi, Arianna;
Chesi, Marta;
Ferrarese, Roberto;
Garcia Perez, Laura;
Grioni, Matteo;
Kumar, Shaji;
Garbitt, Victoria M.;
Sharik, Meaghen E.;
Henderson, Kimberly J.;
Tonon, Giovanni;
Tomura, Michio;
Miwa, Yoshihiro;
Esplugues, Enric;
Flavell, Richard A.;
Huber, Samuel;
Canducci, Filippo;
Rajkumar, Vincent S.;
Bergsagel, P. Leif;
Bellone, Matteo

Publication type:

Article

Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.

Published in:

Science Translational Medicine, 2019, v. 11, n. 494, p. 1, doi. 10.1126/scitranslmed.aau9087

By:

Liu, Huan;
He, Jin;
Koh, Su Pin;
Zhong, Yuping;
Liu, Zhiqiang;
Wang, Zhiqiang;
Zhang, Yujin;
Li, Zongwei;
Tam, Bjorn T.;
Lin, Pei;
Xiao, Min;
Young, Ken H.;
Amini, Behrang;
Starbuck, Michael W.;
Lee, Hans C.;
Navone, Nora M.;
Davis, Richard E.;
Tong, Qiang;
Bergsagel, P. Leif;
Hou, Jian

Publication type:

Article

Type I-conventional dendritic cells support the progression of multiple myeloma in the bone marrow.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1444821

By:

Sayaka Suzuki;
Kazuma Komiya;
Shogo Tsuda;
Miya Yoshino;
Tsuneyasu Kaisho;
Bergsagel, P. Leif;
Koji Kawamura;
Tetsuya Fukuda;
Koji Tokoyoda

Publication type:

Article

Phase Ib/II trial of CYKLONE (cyclophosphamide, carfilzomib, thalidomide and dexamethasone) for newly diagnosed myeloma.

Published in:

British Journal of Haematology, 2015, v. 169, n. 2, p. 219, doi. 10.1111/bjh.13296

By:

Mikhael, Joseph R.;
Reeder, Craig B.;
Libby, Edward N.;
Costa, Luciano J.;
Bergsagel, P. Leif;
Buadi, Francis;
Mayo, Angela;
Nagi Reddy, Sravan K.;
Gano, Katherine;
Dueck, Amylou C.;
Stewart, A. Keith

Publication type:

Article

Long-term survival with cyclophosphamide, bortezomib and dexamethasone induction therapy in patients with newly diagnosed multiple myeloma.

Published in:

British Journal of Haematology, 2014, v. 167, n. 4, p. 563, doi. 10.1111/bjh.13004

By:

Reeder, Craig B.;
Reece, Donna E.;
Kukreti, Vishal;
Mikhael, Joseph R.;
Chen, Christine;
Trudel, Suzanne;
Laumann, Kristina;
Vohra, Harjot;
Fonseca, Rafael;
Bergsagel, P. Leif;
Leis, Jose F.;
Tiedemann, Rodger;
Stewart, A. Keith

Publication type:

Article

Long-term survival with cyclophosphamide, bortezomib and dexamethasone induction therapy in patients with newly diagnosed multiple myeloma.

Published in:

British Journal of Haematology, 2014, v. 165, n. 5, p. 1, doi. 10.1111/bjh.13004

By:

Reeder, Craig B.;
Reece, Donna E.;
Kukreti, Vishal;
Mikhael, Joseph R.;
Chen, Christine;
Trudel, Suzanne;
Laumann, Kristina;
Vohra, Harjot;
Fonseca, Rafael;
Bergsagel, P. Leif;
Leis, Jose F.;
Tiedemann, Rodger;
Stewart, A. Keith

Publication type:

Article

A comparison of lenalidomide/dexamethasone versus cyclophosphamide/lenalidomide/dexamethasone versus cyclophosphamide/bortezomib/dexamethasone in newly diagnosed multiple myeloma.

Published in:

British Journal of Haematology, 2012, v. 156, n. 3, p. 326, doi. 10.1111/j.1365-2141.2011.08949.x

By:

Khan, Meaghan L.;
Reeder, Craig B.;
Kumar, Shaji K.;
Lacy, Marthy Q.;
Reece, Donna E.;
Dispenzieri, Angela;
Gertz, Morie A.;
Greipp, Phillip;
Hayman, Suzanne;
Zeldenhurst, Steven;
Dingli, David;
Lust, John;
Russell, Stephen;
Laumann, Kristina M.;
Mikhael, Joseph R.;
Leif Bergsagel, P.;
Fonseca, Rafael;
Vincent Rajkumar, S.;
Keith Stewart, A.

Publication type:

Article

Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth.

Published in:

Nature Communications, 2015, v. 6, n. 10, p. 8428, doi. 10.1038/ncomms9428

By:

Vallabhapurapu, Subrahmanya D.;
Noothi, Sunil K.;
Pullum, Derek A.;
Lawrie, Charles H.;
Pallapati, Rachel;
Potluri, Veena;
Kuntzen, Christian;
Khan, Sohaib;
Plas, David R.;
Orlowski, Robert Z.;
Chesi, Marta;
Kuehl, W. Michael;
Bergsagel, P. Leif;
Karin, Michael;
Vallabhapurapu, Sivakumar

Publication type:

Article

Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth.

Published in:

Scientific Reports, 2015, p. 8428, doi. 10.1038/ncomms9428

By:

Vallabhapurapu, Subrahmanya D.;
Noothi, Sunil K.;
Pullum, Derek A.;
Lawrie, Charles H.;
Pallapati, Rachel;
Potluri, Veena;
Kuntzen, Christian;
Khan, Sohaib;
Plas, David R.;
Orlowski, Robert Z.;
Chesi, Marta;
Kuehl, W. Michael;
Bergsagel, P. Leif;
Karin, Michael;
Vallabhapurapu, Sivakumar

Publication type:

Article

The PI3K inhibitor GDC-0941 combines with existing clinical regimens for superior activity in multiple myeloma.

Published in:

Oncogene, 2014, v. 33, n. 3, p. 316, doi. 10.1038/onc.2012.594

By:

Munugalavadla, V;
Mariathasan, S;
Slaga, D;
Du, C;
Berry, L;
Del Rosario, G;
Yan, Y;
Boe, M;
Sun, L;
Friedman, L S;
Chesi, M;
Leif Bergsagel, P;
Ebens, A

Publication type:

Article

Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0027996

By:

Suzuki, Erika;
Demo, Susan;
Deu, Edgar;
Keats, Jonathan;
Arastu-Kapur, Shirin;
Leif Bergsagel, P.;
Bennett, Mark K.;
Kirk, Christopher J.

Publication type:

Article

Role of Pirh2 in Mediating the Regulation of p53 and c-Myc.

Published in:

PLoS Genetics, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.pgen.1002360

By:

Hakem, Anne;
Bohgaki, Miyuki;
Lemmers, Bénédicte;
Tai, Elisabeth;
Salmena, Leonardo;
Matysiak-Zablocki, Elzbieta;
Yong-Sam Jung;
Karaskova, Jana;
Kaustov, Lilia;
Duan, Shili;
Madore, Jason;
Boutros, Paul;
Yi Sheng;
Chesi, Marta;
Bergsagel, P. Leif;
Perez-Ordonez, Bayardo;
Mes-Masson, Anne-Marie;
Penn, Linda;
Squire, Jeremy;
Xinbin Chen

Publication type:

Article

Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma.

Published in:

Immunological Reviews, 2003, v. 194, n. 1, p. 96, doi. 10.1034/j.1600-065X.2003.00052.x

By:

Bergsagel, P. Leif;
Kuehl, W. Michael

Publication type:

Article

Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.

Published in:

Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-017-0495-y

By:

López-Iglesias, Ana-Alicia;
Herrero, Ana B.;
Chesi, Marta;
San-Segundo, Laura;
González-Méndez, Lorena;
Hernández-García, Susana;
Misiewicz-Krzeminska, Irena;
Quwaider, Dalia;
Martín-Sánchez, Montserrat;
Primo, Daniel;
Paíno, Teresa;
Bergsagel, P. Leif;
Mehrling, Thomas;
González-Díaz, Marcos;
San-Miguel, Jesús F.;
Mateos, María-Victoria;
Gutiérrez, Norma C.;
Garayoa, Mercedes;
Ocio, Enrique M.

Publication type:

Article

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling.

Published in:

Nature Immunology, 2008, v. 9, n. 12, p. 1364, doi. 10.1038/ni.1678

By:

Vallabhapurapu, Sivakumar;
Matsuzawa, Atsushi;
Zhang, WeiZhou;
Tseng, Ping-Hui;
Keats, Jonathan J;
Wang, Haopeng;
Vignali, Dario A A;
Bergsagel, P Leif;
Karin, Michael

Publication type:

Article

Longitudinal single-cell analysis of a myeloma mouse model identifies subclonal molecular programs associated with progression.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26598-w

By:

Croucher, Danielle C.;
Richards, Laura M.;
Tsofack, Serges P.;
Waller, Daniel;
Li, Zhihua;
Wei, Ellen Nong;
Huang, Xian Fang;
Chesi, Marta;
Bergsagel, P. Leif;
Sebag, Michael;
Pugh, Trevor J.;
Trudel, Suzanne

Publication type:

Article

Signaling Pathways in Myeloma.

Published in:

Clinical Lymphoma & Myeloma, 2009, v. 9, p. S12

By:

Hideshima, Teru;
Mitsiades, Constantine S.;
Stewart, A. Keith;
Bergsagel, P. Leif;
Klein, Bernard

Publication type:

Article

Individualizing Therapy Using Molecular Markers in Multiple Myeloma.

Published in:

Clinical Lymphoma & Myeloma, 2007, v. 7, p. S170

By:

Bergsagel, P. Leif

Publication type:

Article

Immunosurveillance and therapy of multiple myeloma are CD226 dependent.

Published in:

2015

By:

Guillerey, Camille;
Ferrari de Andrade, Lucas;
Vuckovic, Slavica;
Miles, Kim;
Ngiow, Shin Foong;
Yong, Michelle C R;
Teng, Michele W L;
Colonna, Marco;
Ritchie, David S;
Chesi, Martha;
Bergsagel, P Leif;
Hill, Geoffrey R;
Smyth, Mark J;
Martinet, Ludovic;
Chesi, Marta

Publication type:

journal article

Immunosurveillance and therapy of multiple myeloma areCD226 dependent.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 5, p. 2077, doi. 10.1172/JCI77181

By:

Guillerey, Camille;
Ferrari de Andrade, Lucas;
Vuckovic, Slavica;
Miles, Kim;
Shin Foong Ngiow;
Yong, Michelle C. R.;
Teng, Michele W. L.;
Colonna, Marco;
Ritchie, David S.;
Chesi, Martha;
Bergsagel, P. Leif;
Hill, Geoffrey R.;
Smyth, MarkJ.;
Martinet, Ludovic

Publication type:

Article

Molecular pathogenesis of multiple myeloma and its premalignant precursor.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 10, p. 3456, doi. 10.1172/JCI61188

By:

Kuehl, W. Michael;
Bergsagel, P. Leif

Publication type:

Article

Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity.

Published in:

2008

By:

Tiedemann, Rodger E.;
Xinliang Mao;
Chang-Xin Shi;
Yuan Xiao Zhu;
Palmer, Stephen E.;
Sebag, Michael;
Marler, Ron;
Chesi, Marta;
Fonseca, Rafael;
Bergsagel, P. Leif;
Schimmer, Aaron D.;
Stewart, A. Keith;
Mao, Xinliang;
Shi, Chang-Xin;
Zhu, Yuan Xiao

Publication type:

journal article