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Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 2, p. 1, doi. 10.1111/cts.13687
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- Publication type:
- Article
Study of the ketohexokinase inhibitor PF‐06835919 as a clinical cytochrome P450 3A inducer: Integrated use of oral midazolam and liquid biopsy.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 1, p. 1, doi. 10.1111/cts.13644
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- Publication type:
- Article
Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Intravenous Infusions of PF-07304814 (Lufotrelvir) in Participants Hospitalized With COVID-19.
- Published in:
- Open Forum Infectious Diseases, 2023, v. 10, n. 8, p. 1, doi. 10.1093/ofid/ofad355
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- Publication type:
- Article
Effect of Hepatic Impairment on OATP1B Activity: Quantitative Pharmacokinetic Analysis of Endogenous Biomarker and Substrate Drugs.
- Published in:
- Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 5, p. 1058, doi. 10.1002/cpt.2829
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- Publication type:
- Article
A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of danuglipron (PF‐06882961), an oral small‐molecule glucagon‐like peptide‐1 receptor agonist, in Japanese adults with type 2 diabetes mellitus
- Published in:
- Diabetes, Obesity & Metabolism, 2023, v. 25, n. 3, p. 805, doi. 10.1111/dom.14928
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- Publication type:
- Article
Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1201, doi. 10.1002/cpt.2683
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- Publication type:
- Article
Effect of a Ketohexokinase Inhibitor (PF‐06835919) on In Vivo OATP1B Activity: Integrative Risk Assessment Using Endogenous Biomarker and a Probe Drug.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 3, p. 605, doi. 10.1002/cpt.2593
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- Publication type:
- Article
Innovative Randomized Phase I Study and Dosing Regimen Selection to Accelerate and Inform Pivotal COVID‐19 Trial of Nirmatrelvir.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 1, p. 101, doi. 10.1002/cpt.2603
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- Publication type:
- Article
Mini‐Review: Comprehensive Drug Disposition Knowledge Generated in the Modern Human Radiolabeled ADME Study.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 8, p. 428, doi. 10.1002/psp4.12540
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- Publication type:
- Article
353-OR: Oral Small Molecule GLP-1R Agonist PF-06882961 Robustly Reduces Plasma Glucose and Body Weight after 28 Days in Adults with T2DM.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-353-OR
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- Publication type:
- Article
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Liver‐Targeting Acetyl‐CoA Carboxylase Inhibitor (PF‐05221304): A Three‐Part Randomized Phase 1 Study.
- Published in:
- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 4, p. 514, doi. 10.1002/cpdd.782
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- Publication type:
- Article
Effect of Hepatic Organic Anion‐Transporting Polypeptide 1B Inhibition and Chronic Kidney Disease on the Pharmacokinetics of a Liver‐Targeted Glucokinase Activator: A Model‐Based Evaluation.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 4, p. 792, doi. 10.1002/cpt.1419
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- Publication type:
- Article
Efficacy and safety of the glucagon receptor antagonist PF‐06291874: A 12‐week, randomized, dose‐response study in patients with type 2 diabetes mellitus on background metformin therapy.
- Published in:
- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 11, p. 2608, doi. 10.1111/dom.13440
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- Publication type:
- Article
Projecting ADME Behavior and Drug-Drug Interactions in Early Discovery and Development: Application of the Extended Clearance Classification System.
- Published in:
- Pharmaceutical Research, 2016, v. 33, n. 12, p. 3021, doi. 10.1007/s11095-016-2024-z
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- Publication type:
- Article
Response to the Comment on the Article 'Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions'.
- Published in:
- 2013
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- Publication type:
- Letter
Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions.
- Published in:
- Pharmaceutical Research, 2012, v. 29, n. 10, p. 2860, doi. 10.1007/s11095-012-0792-7
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- Publication type:
- Article
Effect of Different Durations and Formulations of Diltiazem on the Single-Dose Pharmacokinetics of Midazolam: How Long Do We Go?
- Published in:
- Journal of Clinical Pharmacology, 2011, v. 51, n. 11, p. 1561, doi. 10.1177/0091270010387141
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- Publication type:
- Article
Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Does Not Affect the Pharmacokinetics of Ethinyl Estradiol or Norethindrone in Healthy Female Subjects.
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- Journal of Clinical Pharmacology, 2011, v. 51, n. 9, p. 1319, doi. 10.1177/0091270010381497
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- Publication type:
- Article
Model-Based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor.
- Published in:
- AAPS Journal, 2011, v. 13, n. 2, p. 179, doi. 10.1208/s12248-011-9254-0
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- Publication type:
- Article
Evaluation of pharmacokinetic parameters and dipeptidyl peptidase-4 inhibition following single doses of sitagliptin in healthy, young Japanese males.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 3, p. 429, doi. 10.1111/j.1365-2125.2010.03852.x
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- Publication type:
- Article
Single-dose pharmacokinetics and pharmacodynamics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2009, v. 68, n. 4, p. 535, doi. 10.1111/j.1365-2125.2009.03465.x
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- Publication type:
- Article
A Thorough QTc Study to Assess the Effect of Sitagliptin, a DPP4 Inhibitor, on Ventricular Repolarization in Healthy Subjects.
- Published in:
- Journal of Clinical Pharmacology, 2009, v. 49, n. 8, p. 937, doi. 10.1177/0091270009337511
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- Publication type:
- Article
Effect of Sitagliptin on the Pharmacokinetics of Simvastatin.
- Published in:
- Journal of Clinical Pharmacology, 2009, v. 49, n. 4, p. 483, doi. 10.1177/0091270008330983
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- Publication type:
- Article
Assessment of the CYP3A-Mediated Drug Interaction Potential of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Volunteers.
- Published in:
- Journal of Clinical Pharmacology, 2009, v. 49, n. 1, p. 80, doi. 10.1177/0091270008326718
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- Publication type:
- Article
Sitagliptin, an dipeptidyl peptidase-4 inhibitor, does not alter the pharmacokinetics of the sulphonylurea, glyburide, in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2008, v. 66, n. 1, p. 36, doi. 10.1111/j.1365-2125.2008.03148.x
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- Publication type:
- Article
Effect of Renal Insufficiency on the Pharmacokinetics of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor.
- Published in:
- Diabetes Care, 2007, v. 30, n. 7, p. 1862, doi. 10.2337/dc06-2545
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- Publication type:
- Article
Multiple-Dose Administration of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Does Not Alter the Single-Dose Pharmacokinetics of Rosiglitazone in Healthy Subjects.
- Published in:
- Journal of Clinical Pharmacology, 2007, v. 47, n. 2, p. 159, doi. 10.1177/0091270006297007
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- Publication type:
- Article
Effect of a Single Cyclosporine Dose on the Single-Dose Pharmacokinetics of Sitagliptin (MK-0431), a Dipeptidyl Peptidase-4 Inhibitor, in Healthy Male Subjects.
- Published in:
- Journal of Clinical Pharmacology, 2007, v. 47, n. 2, p. 165, doi. 10.1177/0091270006296523
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- Publication type:
- Article
Effect of Single Oral Doses of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Incretin and Plasma Glucose Levels after an Oral Glucose Tolerance Test in Patients with Type 2 Diabetes.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 11, p. 4612, doi. 10.1210/jc.2006-1009
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- Publication type:
- Article
Pharmacokinetics and Pharmacodynamic Effects of the Oral DPP-4 Inhibitor Sitagliptin in Middle-Aged Obese Subjects.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 8, p. 876, doi. 10.1177/0091270006289850
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- Publication type:
- Article
Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 3, p. 291, doi. 10.1177/0091270005283467
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- Publication type:
- Article
Effects of Ezetimibe on Cyclosporine Pharmacokinetics in Healthy Subjects.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 3, p. 321, doi. 10.1177/0091270005284851
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- Publication type:
- Article
Interaction of Single-Dose Ezetimibe and Steady-State Cyclosporine in Renal Transplant Patients.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 3, p. 328, doi. 10.1177/0091270005284852
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- Publication type:
- Article
Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double-blind, placebo-controlled studies with single oral doses
- Published in:
- Clinical Pharmacology & Therapeutics, 2005, v. 78, n. 6, p. 675, doi. 10.1016/j.clpt.2005.09.002
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- Publication type:
- Article
Effect of impaired renal function and haemodialysis on the pharmacokinetics of aprepitant.
- Published in:
- 2005
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- Publication type:
- journal article
Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Simvastatin does not have a Clinically Significant Pharmacokinetic Interaction with Fenofibrate in Humans.
- Published in:
- Journal of Clinical Pharmacology, 2004, v. 44, n. 9, p. 1054
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- Publication type:
- Article