Works by Benz, Jörg

Results: 22
    1
    2

    Quantification of Cation–π Interactions in Protein–Ligand Complexes: Crystal-Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion LigandThis work was supported by a grant from the ETH Research Council and by F. Hoffmann-La Roche, Basel. We thank Olivier Kuster, Dr. Thomas Tschopp, and Dr. Alain Gast for the biological assays as well as Dr. Michael Hennig for his support of this work.

    Published in:
    Angewandte Chemie International Edition, 2005, v. 44, n. 28, p. 4400, doi. 10.1002/anie.200500883
    By:
    • Kaspar Schärer;
    • Martin Morgenthaler;
    • Ralph Paulini;
    • Ulrike Obst-Sander;
    • David W. Banner;
    • Daniel Schlatter;
    • Jörg Benz;
    • Martine Stihle;
    • François Diederich
    Publication type:
    Article
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    Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.

    Published in:
    Science Translational Medicine, 2019, v. 11, n. 496, p. N.PAG, doi. 10.1126/scitranslmed.aav5989
    By:
    • Claus, Christina;
    • Ferrara, Claudia;
    • Xu, Wei;
    • Sam, Johannes;
    • Lang, Sabine;
    • Uhlenbrock, Franziska;
    • Albrecht, Rosmarie;
    • Herter, Sylvia;
    • Schlenker, Ramona;
    • Hüsser, Tamara;
    • Diggelmann, Sarah;
    • Challier, John;
    • Mössner, Ekkehard;
    • Hosse, Ralf J.;
    • Hofer, Thomas;
    • Brünker, Peter;
    • Joseph, Catherine;
    • Benz, Jörg;
    • Ringler, Philippe;
    • Stahlberg, Henning
    Publication type:
    Article
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    MoFvAb: Modeling the Fv region of antibodies.

    Published in:
    mAbs (1942-0862), 2015, v. 7, n. 5, p. 838, doi. 10.1080/19420862.2015.1068492
    By:
    • Bujotzek, Alexander;
    • Fuchs, Angelika;
    • Qu, Changtao;
    • Benz, Jörg;
    • Klostermann, Stefan;
    • Antes, Iris;
    • Georges, Guy
    Publication type:
    Article
    7
    8

    A Highly Selective and Versatile Probe Platform for Visualization of Monoacylglycerol Lipase.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 10, p. 1, doi. 10.1002/anie.202413405
    By:
    • Hentsch, Axel;
    • Guberman, Mónica;
    • Radetzki, Silke;
    • Kaushik, Sofia;
    • Huizenga, Mirjam;
    • Paul, Jerome;
    • Schippers, Maria;
    • Benz, Jörg;
    • Kuhn, Bernd;
    • Heer, Dominik;
    • Topp, Andreas;
    • Esteves Gloria, Ludivine;
    • Walter, Alexander;
    • Hochstrasser, Remo;
    • Wittwer, Matthias B.;
    • von Kries, Jens Peter;
    • Collin, Ludovic;
    • Blaising, Julie;
    • van der Stelt, Mario;
    • Lipstein, Noa
    Publication type:
    Article
    9
    10

    A Highly Selective and Versatile Probe Platform for Visualization of Monoacylglycerol Lipase.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 10, p. 1, doi. 10.1002/ange.202413405
    By:
    • Hentsch, Axel;
    • Guberman, Mónica;
    • Radetzki, Silke;
    • Kaushik, Sofia;
    • Huizenga, Mirjam;
    • Paul, Jerome;
    • Schippers, Maria;
    • Benz, Jörg;
    • Kuhn, Bernd;
    • Heer, Dominik;
    • Topp, Andreas;
    • Esteves Gloria, Ludivine;
    • Walter, Alexander;
    • Hochstrasser, Remo;
    • Wittwer, Matthias B.;
    • von Kries, Jens Peter;
    • Collin, Ludovic;
    • Blaising, Julie;
    • van der Stelt, Mario;
    • Lipstein, Noa
    Publication type:
    Article
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    Systematische Untersuchung von Halogenbrücken in Protein-Ligand- Wechselwirkungen.

    Published in:
    Angewandte Chemie, 2011, v. 123, n. 1, p. 329, doi. 10.1002/ange.201006781
    By:
    • Hardegger, Leo A.;
    • Kuhn, Bernd;
    • Spinnler, Beat;
    • Anselm, Lilli;
    • Ecabert, Robert;
    • Stihle, Martine;
    • Gsell, Bernard;
    • Thoma, Ralf;
    • Diez, Joachim;
    • Benz, Jörg;
    • Plancher, Jean-Marc;
    • Hartmann, Guido;
    • Banner, David W.;
    • Haap, Wolfgang;
    • Diederich, François
    Publication type:
    Article
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    18

    Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments.

    Published in:
    ChemMedChem, 2011, v. 6, n. 11, p. 2048, doi. 10.1002/cmdc.201100353
    By:
    • Hardegger, Leo A.;
    • Kuhn, Bernd;
    • Spinnler, Beat;
    • Anselm, Lilli;
    • Ecabert, Robert;
    • Stihle, Martine;
    • Gsell, Bernard;
    • Thoma, Ralf;
    • Diez, Joachim;
    • Benz, Jörg;
    • Plancher, Jean-Marc;
    • Hartmann, Guido;
    • Isshiki, Yoshiaki;
    • Morikami, Kenji;
    • Shimma, Nobuo;
    • Haap, Wolfgang;
    • Banner, David W.;
    • Diederich, François
    Publication type:
    Article
    19

    Design and Biological Evaluation of Novel, Balanced Dual PPARα/γ Agonists.

    Published in:
    ChemMedChem, 2009, v. 4, n. 6, p. 951, doi. 10.1002/cmdc.200800425
    By:
    • Grether, Uwe;
    • Bénardeau, Agnes;
    • Benz, Jörg;
    • Binggeli, Alfred;
    • Blum, Denise;
    • Hilpert, Hans;
    • Kuhn, Bernd;
    • Märki, Hans Peter;
    • Meyer, Markus;
    • Mohr, Peter;
    • Püntener, Kurt;
    • Raab, Susanne;
    • Ruf, Armin;
    • Schlatter, Daniel
    Publication type:
    Article
    20
    21

    Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions.

    Published in:
    Angewandte Chemie International Edition, 2011, v. 50, n. 1, p. 314, doi. 10.1002/anie.201006781
    By:
    • Hardegger, Leo A.;
    • Kuhn, Bernd;
    • Spinnler, Beat;
    • Anselm, Lilli;
    • Ecabert, Robert;
    • Stihle, Martine;
    • Gsell, Bernard;
    • Thoma, Ralf;
    • Diez, Joachim;
    • Benz, Jörg;
    • Plancher, Jean-Marc;
    • Hartmann, Guido;
    • Banner, David W.;
    • Haap, Wolfgang;
    • Diederich, François
    Publication type:
    Article
    22

    Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies.

    Published in:
    Biological Chemistry, 2022, v. 403, n. 5/6, p. 495, doi. 10.1515/hsz-2021-0401
    By:
    • Dickopf, Steffen;
    • Buldun, Can;
    • Vasic, Vedran;
    • Georges, Guy;
    • Hage, Carina;
    • Mayer, Klaus;
    • Forster, Matthias;
    • Wessels, Uwe;
    • Stubenrauch, Kay-Gunnar;
    • Benz, Jörg;
    • Ehler, Andreas;
    • Lauer, Matthias E.;
    • Ringler, Philippe;
    • Kobold, Sebastian;
    • Endres, Stefan;
    • Klein, Christian;
    • Brinkmann, Ulrich
    Publication type:
    Article