Works matching AU Benter, Ibrahim F.

Results: 32

Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.

Published in:

British Journal of Pharmacology, 2005, v. 145, n. 6, p. 829, doi. 10.1038/sj.bjp.0706238

By:

Benter, Ibrahim F.;
Yousif, Mariam H. M.;
Griffiths, Sioned M.;
Benboubetra, Mustapha;
Akhtar, Saghir

Publication type:

Article

Chronic Treatment with Ang-(1-7) Reverses Abnormal Reactivity in the Corpus Cavernosum and Normalizes Diabetes-Induced Changes in the Protein Levels of ACE, ACE2, ROCK1, ROCK2 and Omega-Hydroxylase in a Rat Model of Type 1 Diabetes.

Published in:

Journal of Diabetes Research, 2014, p. 1, doi. 10.1155/2014/142154

By:

Yousif, Mariam H. M.;
Makki, Batoul;
El-Hashim, Ahmed Z.;
Akhtar, Saghir;
Benter, Ibrahim F.

Publication type:

Article

RU28318, an Aldosterone Antagonist, in Combination with an ACE Inhibitor and Angiotensin Receptor Blocker Attenuates Cardiac Dysfunction in Diabetes.

Published in:

Journal of Diabetes Research, 2013, p. 1, doi. 10.1155/2013/427693

By:

Benter, Ibrahim F.;
Babiker, Fawzi;
Al-Rashdan, Ibrahim;
Yousif, Mariam;
Akhtar, Saghir

Publication type:

Article

Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart.

Published in:

Pharmaceutics, 2022, v. 14, n. 12, p. 2673, doi. 10.3390/pharmaceutics14122673

By:

Akhtar, Saghir;
Babiker, Fawzi;
Akhtar, Usman A.;
Benter, Ibrahim F.

Publication type:

Article

Role of epidermal growth factor receptor (EGFR) in corneal remodelling in diabetes.

Published in:

Acta Ophthalmologica (1755375X), 2009, v. 87, n. 8, p. 881, doi. 10.1111/j.1755-3768.2008.01434.x

By:

Akhtar, Saeed;
Almubrad, Turki;
Bron, Anthony J.;
Yousif, Mariam H. M.;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma.

Published in:

PLoS ONE, 2019, v. 14, n. 11, p. 1, doi. 10.1371/journal.pone.0224163

By:

El-Hashim, Ahmed Z.;
Khajah, Maitham A.;
Babyson, Rhema S.;
Renno, Waleed M.;
Ezeamuzie, Charles I.;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Nonviral delivery of synthetic siRNAs in vivo.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3623, doi. 10.1172/JCI33494

By:

Akhtar, Saghir;
Benter, Ibrahim F.

Publication type:

Article

Diabetes-Induced Renal Vascular Dysfunction Is Normalized by Inhibition of Epidermal Growth Factor Receptor Tyrosine Kinase.

Published in:

Journal of Vascular Research, 2005, v. 42, n. 4, p. 284, doi. 10.1159/000085904

By:

Benter, Ibrahim F.;
Yousif, Mariam H. M.;
Hollins, Andrew J.;
Griffiths, Sioned M.;
Akhtar, Saghir

Publication type:

Article

Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways.

Published in:

2012

By:

El-Hashim AZ;
Renno WM;
Raghupathy R;
Abduo HT;
Akhtar S;
Benter IF;
El-Hashim, Ahmed Z;
Renno, Waleed M;
Raghupathy, Raj;
Abduo, Heba T;
Akhtar, Saghir;
Benter, Ibrahim F

Publication type:

journal article

Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 6, p. 1964, doi. 10.1111/j.1476-5381.2012.01905.x

By:

El-Hashim, Ahmed Z;
Renno, Waleed M;
Raghupathy, Raj;
Abduo, Heba T;
Akhtar, Saghir;
Benter, Ibrahim F

Publication type:

Article

Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 5, p. 1390, doi. 10.1111/j.1476-5381.2011.01613.x

By:

Akhtar, Saghir;
Yousif, Mariam HM;
Dhaunsi, Gursev S;
Chandrasekhar, Bindu;
Al-Farsi, Omama;
Benter, Ibrahim F

Publication type:

Article

The cardiac toxicity of PAMAM dendrimer drug delivery systems can be attenuated with the adjunct use of cardioprotective agents.

Published in:

Biomolecules & Biomedicine, 2025, v. 25, n. 4, p. 914, doi. 10.17305/bb.2024.10735

By:

Akhtar, Saghir;
Babiker, Fawzi;
Al-Kouh, Aisha;
Benter, Ibrahim F.

Publication type:

Article

The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.701390

By:

Shraim, Bara A.;
Moursi, Moaz O.;
Benter, Ibrahim F.;
Habib, Abdella M.;
Akhtar, Saghir

Publication type:

Article

Role of 20-Hydroxyeicosatetraenoic and Epoxyeicosatrienoic Acids in the Regulation of Vascular Function in a Model of Hypertension and Endothelial Dysfunction.

Published in:

Pharmacology, 2010, v. 86, n. 3, p. 149, doi. 10.1159/000317521

By:

Yousif, Mariam H. M.;
Benter, Ibrahim F.

Publication type:

Article

Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats.

Published in:

2008

By:

Benter, Ibrahim F.;
Yousif, Mariam H.M.;
Dhaunsi, Gursev S.;
Kaur, Jaspal;
Chappell, Mark C.;
Diz, Debra I.

Publication type:

journal article

Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum.

Published in:

BioMed Research International, 2017, v. 2017, p. 1, doi. 10.1155/2017/5084961

By:

Dhaunsi, Gursev S.;
Yousif, Mariam;
Makki, Batoul;
Akhtar, Saghir;
Benter, Ibrahim F.

Publication type:

Article

The effect of cardiac ischemic preconditioning on rat left ventricular gene expression profile.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A419

By:

Canatan, Halit;
Benter, Ibrahim F.

Publication type:

Article

Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety.

Published in:

Journal of Drug Targeting, 2020, v. 28, n. 7/8, p. 683, doi. 10.1080/1061186X.2020.1797754

By:

Akhtar, Saghir;
Benter, Ibrahim F.;
Danjuma, Mohammed I.;
Doi, Suhail A. R.;
Hasan, Syed S.;
Habib, Abdella M.

Publication type:

Article

The dual targeting of EGFR and ErbB2 with the inhibitor Lapatinib corrects high glucose-induced apoptosis and vascular dysfunction by opposing multiple diabetes-induced signaling changes.

Published in:

Journal of Drug Targeting, 2015, v. 23, n. 6, p. 506, doi. 10.3109/1061186X.2015.1057150

By:

Benter, Ibrahim F.;
Sarkhou, Fatima;
Al-Khaldi, Abeer T.;
Chandrasekhar, Bindu;
Attur, Sreeja;
Dhaunsi, Gursev S.;
Yousif, Mariam H. M.;
Akhtar, Saghir

Publication type:

Article

Toxicogenomics of drug delivery systems: Exploiting delivery system-induced changes in target gene expression to enhance siRNA activity.

Published in:

Journal of Drug Targeting, 2007, v. 15, n. 1, p. 83, doi. 10.1080/10611860601151860

By:

Hollins, Andrew J.;
Omidi, Yadollah;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Sustained Polymeric Delivery of Gene Silencing Antisense ODNs, siRNA, DNAzymes and Ribozymes: In Vitro and In Vivo Studies.

Published in:

Journal of Drug Targeting, 2004, v. 12, n. 6, p. 393, doi. 10.1080/10611860400003858

By:

Khan, Alim;
Benboubetra, Mustapha;
Sayyed, Pakeeza Z.;
Keng Wooi Ng;
Fox, Stephen;
Beck, Gordon;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Toxicogenomics of Non-viral Vectors for Gene Therapy: A Microarray Study of Lipofectin- and Oligofectamine-induced Gene Expression Changes in Human Epithelial Cells.

Published in:

Journal of Drug Targeting, 2003, v. 11, n. 6, p. 311, doi. 10.1080/10611860310001636908

By:

Omidi, Yadollah;
Hollins, Andrew J.;
Benboubetra, Mustapha;
Drayton, Ross;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Targeting the epidermal growth factor receptor (EGFR/ErbB) for the potential treatment of renal pathologies.

Published in:

Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2024.1394997

By:

Tawengi, Mohamed;
Al-Dali, Yazan;
Tawengi, Abdelaziz;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Transactivation of ErbB Family of Receptor Tyrosine Kinases Is Inhibited by Angiotensin-(1-7) via Its Mas Receptor.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141657

By:

Akhtar, Saghir;
Chandrasekhar, Bindu;
Attur, Sreeja;
Dhaunsi, Gursev S.;
Yousif, Mariam H. M.;
Benter, Ibrahim F.

Publication type:

Article

Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132215

By:

Akhtar, Saghir;
Al-Zaid, Bashayer;
El-Hashim, Ahmed Z.;
Chandrasekhar, Bindu;
Attur, Sreeja;
Yousif, Mariam H. M.;
Benter, Ibrahim F.

Publication type:

Article

Activation of ErbB2 and Downstream Signalling via Rho Kinases and ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067813

By:

Akhtar, Saghir;
Yousif, Mariam H. M.;
Dhaunsi, Gursev S.;
Sarkhouh, Fatma;
Chandrasekhar, Bindu;
Attur, Sreeja;
Benter, Ibrahim F.

Publication type:

Article

Activation of EGFR/ERBB2 via Pathways Involving ERK1/2, P38 MAPK, AKT and FOXO Enhances Recovery of Diabetic Hearts from Ischemia-Reperfusion Injury.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039066

By:

Akhtar, Saghir;
Yousif, Mariam H. M.;
Chandrasekhar, Bindu;
Benter, Ibrahim F.

Publication type:

Article

FPTIII Mitigates Peroxisome-Mediated Oxidative Stress in Kidneys of Spontaneously Hypertensive Diabetic Rats.

Published in:

Kidney & Blood Pressure Research, 2010, v. 33, n. 1, p. 60, doi. 10.1159/000289574

By:

Dhaunsi, Gursev S.;
Yousif, Mariam H. M.;
Benter, Ibrahim F.

Publication type:

Article

Role of Ca<sup>2+</sup>/calmodulin-dependent protein kinase II in development of vascular dysfunction in diabetic rats with hypertension.

Published in:

Cell Biochemistry & Function, 2008, v. 26, n. 2, p. 256, doi. 10.1002/cbf.1446

By:

Yousif, Mariam H. M.;
Akhtar, Saghir;
Walther, Thomas;
Benter, Ibrahim F.

Publication type:

Article

Cardioprotection from ischemia-reperfusion injury due to Ras-GTPase inhibition is attenuated by glibenclamide in the globally ischemic heart.

Published in:

Cell Biochemistry & Function, 2007, v. 25, n. 4, p. 455, doi. 10.1002/cbf.1353

By:

Al-Rashdan, Ibrahim;
Canatan, Halit;
Al-Maghrebi, May;
Yousif, Mariam H. M.;
Khan, Shah A.;
Benter, Ibrahim F.

Publication type:

Article

Phosphoinositide 3-kinase mediated signalling contributes to development of diabetes-induced abnormal vascular reactivity of rat carotid artery.

Published in:

Cell Biochemistry & Function, 2006, v. 24, n. 1, p. 13, doi. 10.1002/cbf.1278

By:

Yousif, Mariam H. M.;
Benter, Ibrahim F.;
Hares, Nisreen;
Canatan, Halit;
Akhtar, Saghir

Publication type:

Article

Nanotoxicology of Dendrimers in the Mammalian Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs Recovery of Cardiac Function Following Ischemia-Reperfusion Injury.

Published in:

International Journal of Nanomedicine, 2020, v. 15, p. 4393, doi. 10.2147/IJN.S255202

By:

Babiker, Fawzi;
Benter, Ibrahim F;
Akhtar, Saghir

Publication type:

Article