Works by Belvisi, Maria G.

Results: 65

Prostanoids and the Cough Reflex.

Published in:

Lung (0341-2040), 2010, v. 188, p. 9, doi. 10.1007/s00408-009-9190-2

By:

Maher, Sarah A.;
Belvisi, Maria G.

Publication type:

Article

Preclinical Assessment of Novel Therapeutics on the Cough Reflex: Cannabinoid Agonists as Potential Antitussives.

Published in:

Lung (0341-2040), 2008, v. 186, p. 66, doi. 10.1007/s00408-007-9028-8

By:

Belvisi, Maria G.

Publication type:

Article

Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease.

Published in:

2009

By:

Belvisi, Maria G;
Mitchell, Jane A

Publication type:

journal article

Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF.

Published in:

2004

By:

Clarke, Deborah L.;
Belvisi, Maria G.;
Catley, Matthew C.;
Yacoub, Magdi H.;
Newton, Robert;
Giembycz, Mark A.

Publication type:

journal article

E-Ring 8-isoprostanes inhibit ACh release from parasympathetic nerves innervating guinea-pig trachea through agonism of prostanoid receptors of the EP3-subtype.

Published in:

British Journal of Pharmacology, 2004, v. 141, n. 4, p. 600, doi. 10.1038/sj.bjp.0705648

By:

Clarke, Deborah L.;
Giembycz, Mark A.;
Patel, Hema J.;
Belvisi, Maria G.

Publication type:

Article

Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation.

Published in:

2003

By:

Patel, Hema J.;
Birrell, Mark A.;
Crispino, Natascia;
Hele, David J.;
Venkatesan, Priya;
Barnes, Peter J.;
Yacoub, Magdi H.;
Belvisi, Maria G.

Publication type:

journal article

Functional characterization and biomarker identification in the Brown Norway model of allergic airway inflammation.

Published in:

British Journal of Pharmacology, 2002, v. 137, n. 2, p. 263, doi. 10.1038/sj.bjp.0704865

By:

Underwood, Stephen L.;
Haddad, El-Bdaoui;
Birrell, Mark A.;
McCluskie, Kerryn;
Pecoraro, Michaela;
Dabrowski, Dominika;
Webber, Stephen E.;
Foster, Martyn L.;
Belvisi, Maria G.

Publication type:

Article

Effect of dopamine receptor agonists on sensory nerve activity: possible therapeutic targets for the treatment of asthma and COPD.

Published in:

British Journal of Pharmacology, 2002, v. 136, n. 4, p. 620, doi. 10.1038/sj.bjp.0704758

By:

Birrell, Mark A.;
Crispino, Natascia;
Hele, David J.;
Patel, Hema J.;
Yacoub, Magdi H.;
Barnes, Peter J.;
Belvisi, Maria G.

Publication type:

Article

Evidence that the anti-spasmogenic effect of the β-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase.

Published in:

British Journal of Pharmacology, 2001, v. 133, n. 8, p. 1201, doi. 10.1038/sj.bjp.0704213

By:

Spicuzza, Lucia;
Belvisi, Maria G;
Birrell, Mark A;
Barnes, Peter J;
Hele, David J;
Giembycz, Mark A

Publication type:

Article

Role of p38 MAP kinase in LPS-induced airway inflammation in the rat.

Published in:

British Journal of Pharmacology, 2001, v. 132, n. 8, p. 1715, doi. 10.1038/sj.bjp.0704022

By:

Haddad, El-Bdaoui;
Birrell, Mark;
McCluskie, Kerryn;
Ling, Andrea;
Webber, Stephen E;
Foster, Martyn L;
Belvisi, Maria G

Publication type:

Article

Chronic systemic administration of salmeterol to rats promotes pulmonary β2-adrenoceptor desensitization and down-regulation of Gsα.

Published in:

British Journal of Pharmacology, 2001, v. 132, n. 6, p. 1261, doi. 10.1038/sj.bjp.0703946

By:

Finney, Paul A;
Donnelly, Louise E;
Belvisi, Maria G;
Chuang, Tsu-Tshen;
Birrell, Mark;
Harris, Andrew;
Mak, Judith C W;
Scorer, Carol;
Barnes, Peter J;
Adcock, Ian M;
Giembycz, Mark A

Publication type:

Article

Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats.

Published in:

British Journal of Pharmacology, 2001, v. 132, n. 2, p. 481, doi. 10.1038/sj.bjp.0703847

By:

Hele, Dave J;
Birrell, Mark A;
Webber, Stephen E;
Foster, Martyn L;
Belvisi, Maria G

Publication type:

Article

Effect of endothelin antagonists, including the novel ET(A) receptor antagonist LBL 031, on endothelin-1 and lipopolysaccharide-induced microvascular leakage in rat airways.

Published in:

2000

By:

Hele, Dave J;
Birrell, Mark A;
Webber, Stephen E;
Foster, Martyn L;
Belvisi, Maria G;
Hele, D J;
Birrell, M A;
Webber, S E;
Foster, M L;
Belvisi, M G

Publication type:

journal article

Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves.

Published in:

2000

By:

Spicuzza, Lucia;
Haddad, El-Bdaoui;
Birrell, Mark;
Ling, Andrea;
Clarke, Deborah;
Venkatesan, Priya;
Barnes, Peter J;
Belvisi, Maria G;
Spicuzza, L;
Haddad, E B;
Birrell, M;
Ling, A;
Clarke, D;
Venkatesan, P;
Barnes, P J;
Belvisi, M G

Publication type:

journal article

Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.

Published in:

British Journal of Pharmacology, 1999, v. 128, n. 2, p. 327, doi. 10.1038/sj.bjp.0702779

By:

Bernareggi, Micaela M;
Belvisi, Maria G;
Patel, Hema;
Barnes, Peter J;
Giembycz, Mark A

Publication type:

Article

Pharmacological characterization of the muscarinic receptor antagonist, glycopyrrolate, in human and guinea-pig airways.

Published in:

1999

By:

Haddad, El-Bdaoui;
Patel, Hema;
Keeling, Joelle E;
Yacoub, Magdi H;
Barnes, Peter J;
Belvisi, Maria G;
Haddad, E B;
Patel, H;
Keeling, J E;
Yacoub, M H;
Barnes, P J;
Belvisi, M G

Publication type:

journal article

Targeting Alveolar Repair in Idiopathic Pulmonary Fibrosis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2021, v. 65, n. 4, p. 347, doi. 10.1165/rcmb.2020-0476TR

By:

Ptasinski, Victoria A.;
Stegmayr, John;
Belvisi, Maria G.;
Wagner, Darcy E.;
Murray, Lynne A.

Publication type:

Article

Effects of Prostaglandin E2 and cAMP Elevating Drugs on GM-CSF Release by Cultured Human Airway Smooth Muscle Cells.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2001, v. 24, n. 1, p. 44, doi. 10.1165/ajrcmb.24.1.4027

By:

Lazzeri, Nicola;
Belvisi, Maria G.;
Patel, Hema J.;
Yacoub, Magdi H.;
Chung, K. Fan;
Mitchell, Jane A.

Publication type:

Article

A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of Pseudomonas aeruginosa in Patients with Bronchiectasis.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2024, v. 210, n. 1, p. 35, doi. 10.1164/rccm.202308-1403OC

By:

Long, Merete B.;
Gilmour, Amy;
Kehl, Margaret;
Tabor, David E.;
Keller, Ashley E.;
Warrener, Paul;
Gopalakrishnan, Vancheswaran;
Rosengren, Sanna;
Crichton, Megan L.;
McIntosh, Eve;
Giam, Yan Hui;
Keir, Holly R.;
Brailsford, Wayne;
Hughes, Rod;
Belvisi, Maria G.;
Sellman, Bret R.;
DiGiandomenico, Antonio;
Chalmers, James D.

Publication type:

Article

APREPITANT FOR THE TREATMENT OF COUGH IN LUNG CANCER: A RANDOMISED PLACEBO-CONTROLLED TRIAL.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2021, v. 203, n. 6, p. E1

By:

Smith, Jaclyn A;
Harle, Amélie;
Dockry, Rachel;
Holt, Kimberley;
Russell, Philip;
Molassioti, Alexander;
Yorke, Janelle;
Robinson, Ryan;
Birrell, Mark A.;
Belvisi, Maria G.;
Blackhall, Fiona

Publication type:

Article

Aprepitant for Cough in Lung Cancer. A Randomized Placebo-controlled Trial and Mechanistic Insights.

Published in:

2021

By:

Smith, Jaclyn A.;
Harle, Am´elie;
Dockry, Rachel;
Holt, Kimberley;
Russell, Philip;
Molassiotis, Alex;
Yorke, Janelle;
Robinson, Ryan;
Birrell, Mark A.;
Belvisi, Maria G.;
Blackhall, Fiona;
Harle, Amélie

Publication type:

journal article

Downregulation of MicroRNA-126 Augments DNA Damage Response in Cigarette Smokers and Patients with Chronic Obstructive Pulmonary Disease.

Published in:

2018

By:

Paschalaki, Koralia E.;
Zampetaki, Anna;
Baker, Jonathan R.;
Birrell, Mark A.;
Starke, Richard D.;
Belvisi, Maria G.;
Donnelly, Louise E.;
Mayr, Manuel;
Randi, Anna M.;
Barnes, Peter J.

Publication type:

journal article

XEN-D0501, a Novel Transient Receptor Potential Vanilloid 1 Antagonist, Does Not Reduce Cough in Patients with Refractory Cough.

Published in:

2017

By:

Belvisi, Maria G.;
Birrell, Mark A.;
Wortley, Michael A.;
Maher, Sarah A.;
Satia, Imran;
Badri, Huda;
Holt, Kimberley;
Round, Patrick;
McGarvey, Lorcan;
Ford, John;
Smith, Jaclyn A.

Publication type:

journal article

Neurophenotypes in Airway Diseases. Insights from Translational Cough Studies.

Published in:

2016

By:

Belvisi, Maria G.;
Birrell, Mark A.;
Khalid, Saifudin;
Wortley, Michael A.;
Dockry, Rachel;
Coote, Julie;
Holt, Kimberley;
Dubuis, Eric;
Kelsall, Angela;
Maher, Sarah A.;
Bonvini, Sara;
Woodcock, Ashley;
Smith, Jaclyn A.

Publication type:

journal article

Lung-resident eosinophils represent a distinct regulatory eosinophil subset.

Published in:

2016

By:

Mesnil, Claire;
Raulier, Stéfanie;
Paulissen, Geneviève;
Xue Xiao;
Birrell, Mark A.;
Pirottin, Dimitri;
Janss, Thibaut;
Starkl, Philipp;
Ramery, Eve;
Henket, Monique;
Schleich, Florence N.;
Radermecker, Marc;
Thielemans, Kris;
Gillet, Laurent;
Thiry, Marc;
Belvisi, Maria G.;
Louis, Renaud;
Desmet, Christophe;
Marichal, Thomas;
Bureau, Fabrice

Publication type:

journal article

Characterisation of pharmacokinetics, safety and tolerability in a first‐in‐human study for AZD8154, a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 1, p. 260, doi. 10.1111/bcp.14956

By:

Sadiq, Muhammad Waqas;
Asimus, Sara;
Belvisi, Maria G.;
Brailsford, Wayne;
Fransson, Rebecca;
Fuhr, Rainard;
Hagberg, Anette;
Hashemi, Mahdi;
Jellesmark Jensen, Tina;
Jonsson, Julia;
Keen, Christina;
Körnicke, Thomas;
Kristensson, Cecilia;
Mäenpää, Jukka;
Necander, Sofia;
Nemes, Szilárd;
Betts, Joanne

Publication type:

Article

Role of EP2 and EP4 receptors in airway microvascular leak induced by prostaglandin E2.

Published in:

2016

By:

Jones, Victoria C;
Birrell, Mark A;
Maher, Sarah A;
Griffiths, Mark;
Grace, Megan;
O'Donnell, Valerie B;
Clark, Stephen R;
Belvisi, Maria G

Publication type:

journal article

The role of adenylyl cyclase isoform 6 in β-adrenoceptor signalling in murine airways.

Published in:

2015

By:

Birrell, Mark A;
Bonvini, Sara J;
Wortley, Michael A;
Buckley, James;
Yew-Booth, Liang;
Maher, Sarah A;
Dale, Nicole;
Dubuis, Eric D;
Belvisi, Maria G

Publication type:

journal article

The role of adenylyl cyclase isoform 6 in β-adrenoceptor signalling in murine airways.

Published in:

British Journal of Pharmacology, 2015, v. 172, n. 1, p. 131, doi. 10.1111/bph.12905

By:

Birrell, Mark A;
Bonvini, Sara J;
Wortley, Michael A;
Buckley, James;
Yew ‐ Booth, Liang;
Maher, Sarah A;
Dale, Nicole;
Dubuis, Eric D;
Belvisi, Maria G

Publication type:

Article

Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor.

Published in:

2013

By:

Birrell MA;
Maher SA;
Buckley J;
Dale N;
Bonvini S;
Raemdonck K;
Pullen N;
Giembycz MA;
Belvisi MG;
Birrell, Mark A;
Maher, Sarah A;
Buckley, James;
Dale, Nicole;
Bonvini, Sara;
Raemdonck, Kristof;
Pullen, Nick;
Giembycz, Mark A;
Belvisi, Maria G

Publication type:

journal article

Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor.

Published in:

British Journal of Pharmacology, 2013, v. 168, n. 1, p. 129, doi. 10.1111/j.1476-5381.2012.02088.x

By:

Birrell, Mark A;
Maher, Sarah A;
Buckley, James;
Dale, Nicole;
Bonvini, Sara;
Raemdonck, Kristof;
PullEN, Nick;
Giembycz, Mark A;
Belvisi, Maria G

Publication type:

Article

Neuroregulation by vasoactive intestinal peptide (VIP) of mucus secretion in ferret trachea: activation of BK(Ca) channels and inhibition of neurotransmitter release.

Published in:

1999

By:

Liu, Yu-Chih;
Patel, Hema J;
Khawaja, Aamir M;
Belvisi, Maria G;
Rogers, Duncan F;
Liu, Y C;
Patel, H J;
Khawaja, A M;
Belvisi, M G;
Rogers, D F

Publication type:

journal article

Prostaglandin E2 suppression of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by interacting with prostanoid receptors of the EP3-subtype.

Published in:

British Journal of Pharmacology, 1998, v. 123, n. 6, p. 1246, doi. 10.1038/sj.bjp.0701720

By:

Spicuzza, Lucia;
Giembycz, Mark A.;
Barnes, Peter J.;
Belvisi, Maria G.

Publication type:

Article

Naloxone-insensitive inhibition of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by the novel opioid, nociceptin.

Published in:

British Journal of Pharmacology, 1997, v. 120, n. 5, p. 735, doi. 10.1038/sj.bjp.0701013

By:

Patel, Hema J;
Giembycz, Mark A;
Spicuzza, Lucia;
Barnes, Peter J;
Belvisi, Maria G

Publication type:

Article

Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type.

Published in:

British Journal of Pharmacology, 1997, v. 120, n. 5, p. 910, doi. 10.1038/sj.bjp.0700963

By:

Belvisi, Maria G;
Saunders, Michael A;
Haddad, El-Bdaoui;
Hirst, Stuart J;
Yacoub, Magdi H;
Barnes, Peter J;
Mitchell, Jane A

Publication type:

Article

Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: suppression by dexamethasone.

Published in:

British Journal of Pharmacology, 1997, v. 120, n. 4, p. 545, doi. 10.1038/sj.bjp.0700998

By:

Saunders, Michael A.;
Mitchell, Jane A.;
Seldon, Paul M.;
Yacoub, Magdi H.;
Barnes, Peter J.;
Giembycz, Mark A.;
Belvisi, Maria G.

Publication type:

Article

Ciclesonide: A Viewpoint by Maria G. Belvisi.

Published in:

Drugs, 2004, v. 64, n. 5, p. 520, doi. 10.2165/00003495-200464050-00006

By:

Belvisi, Maria G.

Publication type:

Article

Back to the future: re-establishing guinea pig in vivo asthma models.

Published in:

Clinical Science, 2020, v. 134, n. 11, p. 1219, doi. 10.1042/CS20200394

By:

Adner, Mikael;
Canning, Brendan J.;
Meurs, Herman;
Ford, William;
Ramírez, Patricia Ramos;
van den Berg, Mariska P. M.;
Birrell, Mark A.;
Stoffels, Eva;
Lundblad, Lennart K. A.;
Nilsson, Gunnar P.;
Olsson, Henric K.;
Belvisi, Maria G.;
Dahlén, Sven-Erik

Publication type:

Article

TRPA1 agonists evoke coughing in guinea pig and human volunteers.

Published in:

2009

By:

Birrell MA;
Belvisi MG;
Grace M;
Sadofsky L;
Faruqi S;
Hele DJ;
Maher SA;
Freund-Michel V;
Morice AH;
Birrell, Mark A;
Belvisi, Maria G;
Grace, Megan;
Sadofsky, Laura;
Faruqi, Shoaib;
Hele, David J;
Maher, Sarah A;
Freund-Michel, Véronique;
Morice, Alyn H

Publication type:

journal article

Prostaglandin E2 mediates cough via the EP3 receptor: implications for future disease therapy.

Published in:

2009

By:

Maher SA;
Birrell MA;
Belvisi MG;
Maher, Sarah A;
Birrell, Mark A;
Belvisi, Maria G

Publication type:

journal article

Iκ-B Kinase-2 Inhibitor Blocks Inflammation in Human Airway Smooth Muscle and a Rat Model of Asthma.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2005, v. 172, n. 8, p. 962, doi. 10.1164/rccm.200412-1647OC

By:

Birrell, Mark A.;
Hardaker, Elizabeth;
Wong, Sissie;
McCluskie, Kerryn;
Catley, Matthew;
De Alba, Jorge;
Newton, Robert;
Haj-Yahia, Saleem;
Pun, K. Tao;
Watts, Clarissa J.;
Shaw, Robert J.;
Savage, Tony J.;
Belvisi, Maria G.

Publication type:

Article

Steroid-resistant Inflammation in a Rat Model of Chronic Obstructive Pulmonary Disease Is Associated with a Lack of Nuclear Factor-κB Pathway Activation.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2005, v. 172, n. 1, p. 74, doi. 10.1164/rccm.200409-1257OC

By:

Birrell, Mark A.;
Wong, Sissie;
Hele, David J.;
McCluskie, Kerryn;
Hardaker, Elizabeth;
Belvisi, Maria G.

Publication type:

Article

Chronic lung diseases: prospects for regeneration and repair.

Published in:

European Respiratory Review, 2021, v. 30, n. 159, p. 1, doi. 10.1183/16000617.0213-2020

By:

Barnes, Peter J.;
Anderson, Gary P.;
Fagerås, Malin;
Belvisi, Maria G.

Publication type:

Article

Modelling the asthma phenotype: impact of cigarette smoke exposure.

Published in:

2018

By:

Belvisi, Maria G.;
Baker, Katie;
Malloy, Nicole;
Raemdonck, Kristof;
Dekkak, Bilel;
Pieper, Michael;
Nials, Anthony T.;
Birrell, Mark A.

Publication type:

journal article

AZD9567 versus prednisolone in patients with active rheumatoid arthritis: A phase IIa, randomized, double‐blind, efficacy, and safety study.

Published in:

CTS: Clinical & Translational Science, 2023, v. 16, n. 12, p. 2494, doi. 10.1111/cts.13624

By:

van Laar, Jacob M.;
Lei, Alejhandra;
Safy‐Khan, Mary;
Almquist, Joachim;
Belfield, Graham;
Edman, Karl;
Öberg, Lisa;
Angermann, Bastian R.;
Dillmann, Inken;
Berntsson, Pia;
Etal, Damla;
Dainty, Ian;
Astbury, Carol;
Belvisi, Maria G.;
Nemes, Szilárd;
Platt, Adam;
Prothon, Susanne;
Samuelsson, Sara;
Svanberg, Petter;
Keen, Christina

Publication type:

Article

Effect of traffic-related air pollution on cough in adults with polymorphisms in several cough-related genes.

Published in:

2022

By:

Yoon, Michael;
Ryu, Min Hyung;
Huff, Ryan D.;
Belvisi, Maria G.;
Smith, Jaclyn;
Carlsten, Chris

Publication type:

Letter

New Advances and Potential Therapies for the Treatment of Asthma.

Published in:

BioDrugs, 2004, v. 18, n. 4, p. 211, doi. 10.2165/00063030-200418040-00001

By:

Belvisi, Maria G.;
Hele, David J.;
Birrell, Mark A.

Publication type:

Article

Bronchodilator activity of bitter tastants in human tissue.

Published in:

2011

By:

Belvisi, Maria G.;
Dale, Nicole;
Birrell, Mark A.;
Canning, Brendan J.

Publication type:

Letter

Theobromine inhibits sensory nerve activation and cough.

Published in:

FASEB Journal, 2005, v. 19, n. 2, p. 231, doi. 10.1096/fj.04-1990fje

By:

Usmani, Omar S.;
Belvisi, Maria G.;
Patel, Hema J.;
Crispino, Natascia;
Birrell, Mark A.;
Korbonits, Márta;
Korbonits, Dezso;
Barnes, Peter J.

Publication type:

Article

PI3Kγδ inhibition suppresses key disease features in a rat model of asthma.

Published in:

Respiratory Research, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12931-024-02814-1

By:

Pinkerton, James W.;
Preite, Silvia;
Piras, Antonio;
Zervas, Dimitrios;
Markou, Thomais;
Freeman, Mark S.;
Hofving, Tobias;
Ivarsson, Emil;
Bonvini, Sara J.;
Brailsford, Wayne;
Yrlid, Linda;
Belvisi, Maria G.;
Birrell, Mark A.

Publication type:

Article