Works by Beltran, Himisha

Results: 65
    1

    Activity of Platinum-Based Chemotherapy in Patients With Advanced Prostate Cancer With and Without DNA Repair Gene Aberrations.

    Published in:
    JAMA Network Open, 2020, v. 3, n. 10, p. e2021692, doi. 10.1001/jamanetworkopen.2020.21692
    By:
    • Schmid, Sabine;
    • Omlin, Aurelius;
    • Higano, Celestia;
    • Sweeney, Christopher;
    • Martinez Chanza, Nieves;
    • Mehra, Niven;
    • Kuppen, Malou C. P.;
    • Beltran, Himisha;
    • Condeduca, Vincenza;
    • Vargas Pivato de Almeida, Daniel;
    • Cotait Maluf, Fernando;
    • Oh, William K.;
    • Tsao, Che-Kai;
    • Sartor, Oliver;
    • Ledet, Elisa;
    • Di Lorenzo, Giuseppe;
    • Yip, Steven M.;
    • Chi, Kim N.;
    • Bianchini, Diletta;
    • De Giorgi, Ugo
    Publication type:
    Article
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    DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.

    Published in:
    Oncologist, 2022, v. 27, n. 11, p. 940, doi. 10.1093/oncolo/oyac161
    By:
    • Yao, James;
    • Bergsland, Emily;
    • Aggarwal, Rahul;
    • Aparicio, Ana;
    • Beltran, Himisha;
    • Crabtree, Judy S;
    • Hann, Christine L;
    • Ibrahim, Toni;
    • Byers, Lauren A;
    • Sasano, Hironobu;
    • Umejiego, John;
    • Pavel, Marianne
    Publication type:
    Article
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    Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53874-2
    By:
    • Chatterjee, Shankha S.;
    • Linares, Juan F.;
    • Cid-Diaz, Tania;
    • Duran, Angeles;
    • Khan, Mohd. Imran K.;
    • Osrodek, Marta;
    • Brady, Nicholas J.;
    • Reina-Campos, Miguel;
    • Marzio, Antonio;
    • Venkadakrishnan, Varadha Balaji;
    • Bakht, Martin K.;
    • Khani, Francesca;
    • Mosquera, Juan Miguel;
    • Robinson, Brian D.;
    • Moyer, Jenna;
    • Elemento, Olivier;
    • Hsieh, Andrew C.;
    • Goodrich, David W.;
    • Rickman, David S.;
    • Beltran, Himisha
    Publication type:
    Article
    6

    Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51156-5
    By:
    • Venkadakrishnan, Varadha Balaji;
    • Presser, Adam G.;
    • Singh, Richa;
    • Booker, Matthew A.;
    • Traphagen, Nicole A.;
    • Weng, Kenny;
    • Voss, Nathaniel C. E.;
    • Mahadevan, Navin R.;
    • Mizuno, Kei;
    • Puca, Loredana;
    • Idahor, Osasenaga;
    • Ku, Sheng-Yu;
    • Bakht, Martin K.;
    • Borah, Ashir A.;
    • Herbert, Zachary T.;
    • Tolstorukov, Michael Y.;
    • Barbie, David A.;
    • Rickman, David S.;
    • Brown, Myles;
    • Beltran, Himisha
    Publication type:
    Article
    7

    Impact of early detection on cancer curability: A modified Delphi panel study.

    Published in:
    PLoS ONE, 2022, v. 17, n. 12, p. 1, doi. 10.1371/journal.pone.0279227
    By:
    • Schwartzberg, Lee;
    • Broder, Michael S.;
    • Ailawadhi, Sikander;
    • Beltran, Himisha;
    • Blakely, L. Johnetta;
    • Budd, G. Thomas;
    • Carr, Laurie;
    • Cecchini, Michael;
    • Cobb, Patrick;
    • Kansal, Anuraag;
    • Kim, Ashley;
    • Monk, Bradley J.;
    • Wong, Deborah J.;
    • Campos, Cynthia;
    • Yermilov, Irina
    Publication type:
    Article
    8

    The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.

    Published in:
    Molecular Oncology, 2022, v. 16, n. 12, p. 2384, doi. 10.1002/1878-0261.13204
    By:
    • van der Mijn, Johannes C.;
    • Eng, Kenneth W.;
    • Chandra, Pooja;
    • Fernandez, Evan;
    • Ramazanoglu, Sinan;
    • Sigaras, Alexandros;
    • Oromendia, Clara;
    • Gudas, Lorraine J.;
    • Tagawa, Scott T.;
    • Nanus, David M.;
    • Faltas, Bishoy F.;
    • Beltran, Himisha;
    • Sternberg, Cora N.;
    • Elemento, Olivier;
    • Sboner, Andrea;
    • Mosquera, Juan Miguel;
    • Molina, Ana M.
    Publication type:
    Article
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    Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26042-z
    By:
    • Cejas, Paloma;
    • Xie, Yingtian;
    • Font-Tello, Alba;
    • Lim, Klothilda;
    • Syamala, Sudeepa;
    • Qiu, Xintao;
    • Tewari, Alok K.;
    • Shah, Neel;
    • Nguyen, Holly M.;
    • Patel, Radhika A.;
    • Brown, Lisha;
    • Coleman, Ilsa;
    • Hackeng, Wenzel M.;
    • Brosens, Lodewijk;
    • Dreijerink, Koen M. A.;
    • Ellis, Leigh;
    • Alaiwi, Sarah Abou;
    • Seo, Ji-Heui;
    • Baca, Sylvan;
    • Beltran, Himisha
    Publication type:
    Article
    12

    Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23780-y
    By:
    • Brady, Nicholas J.;
    • Bagadion, Alyssa M.;
    • Singh, Richa;
    • Conteduca, Vincenza;
    • Van Emmenis, Lucie;
    • Arceci, Elisa;
    • Pakula, Hubert;
    • Carelli, Ryan;
    • Khani, Francesca;
    • Bakht, Martin;
    • Sigouros, Michael;
    • Bareja, Rohan;
    • Sboner, Andrea;
    • Elemento, Olivier;
    • Tagawa, Scott;
    • Nanus, David M.;
    • Loda, Massimo;
    • Beltran, Himisha;
    • Robinson, Brian;
    • Rickman, David S.
    Publication type:
    Article
    13

    Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer.

    Published in:
    2020
    By:
    • Beltran, Himisha;
    • Romanel, Alessandro;
    • Conteduca, Vincenza;
    • Casiraghi, Nicola;
    • Sigouros, Michael;
    • Franceschini, Gian Marco;
    • Orlando, Francesco;
    • Fedrizzi, Tarcisio;
    • Sheng-Yu Ku;
    • Dann, Emma;
    • Alonso, Alicia;
    • Miguel Mosquera, Juan;
    • Sboner, Andrea;
    • Jenny Xiang;
    • Elemento, Olivier;
    • Nanus, David M.;
    • Tagawa, Scott T.;
    • Benelli, Matteo;
    • Demichelis, Francesca;
    • Ku, Sheng-Yu
    Publication type:
    journal article
    14

    N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.

    Published in:
    Journal of Clinical Investigation, 2019, v. 129, n. 9, p. 3924, doi. 10.1172/JCI127961
    By:
    • Berger, Adeline;
    • Brady, Nicholas J.;
    • Bareja, Rohan;
    • Robinson, Brian;
    • Conteduca, Vincenza;
    • Augello, Michael A.;
    • Puca, Loredana;
    • Ahmed, Adnan;
    • Dardenne, Etienne;
    • Xiaodong Lu;
    • Inah Hwang;
    • Bagadion, Alyssa M.;
    • Sboner, Andrea;
    • Elemento, Olivier;
    • Paik, Jihye;
    • Jindan Yu;
    • Barbieri, Christopher E.;
    • Dephoure, Noah;
    • Beltran, Himisha;
    • Rickman, David S.
    Publication type:
    Article
    15
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    The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-21711-5
    By:
    • Quaglia, Fabio;
    • Krishn, Shiv Ram;
    • Sossey-Alaoui, Khalid;
    • Rana, Priyanka Shailendra;
    • Pluskota, Elzbieta;
    • Park, Pyung Hun;
    • Shields, Christopher D.;
    • Lin, Stephen;
    • McCue, Peter;
    • Kossenkov, Andrew V.;
    • Wang, Yanqing;
    • Goodrich, David W.;
    • Ku, Sheng-Yu;
    • Beltran, Himisha;
    • Kelly, William K.;
    • Corey, Eva;
    • Klose, Maja;
    • Bandtlow, Christine;
    • Liu, Qin;
    • Altieri, Dario C.
    Publication type:
    Article
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    Implementing evidence‐based strategies for men with biochemically recurrent and advanced prostate cancer: Consensus recommendations from the US Prostate Cancer Conference 2024.

    Published in:
    Cancer (0008543X), 2025, v. 131, n. 1, p. 1, doi. 10.1002/cncr.35612
    By:
    • Bryce, Alan H.;
    • Agarwal, Neeraj;
    • Beltran, Himisha;
    • Hussain, Maha H.;
    • Sartor, Oliver;
    • Shore, Neal;
    • Antonarakis, Emmanuel S.;
    • Armstrong, Andrew J.;
    • Calais, Jeremie;
    • Carducci, Michael A.;
    • Dorff, Tanya Barauskas;
    • Efstathiou, Jason A.;
    • Gleave, Martin;
    • Gomella, Leonard G.;
    • Higano, Celestia;
    • Hope, Thomas A.;
    • Iagaru, Andrei;
    • Morgans, Alicia K.;
    • Morris, David S.;
    • Morris, Michael J.
    Publication type:
    Article
    21

    Insulin resistance during androgen deprivation therapy in men with prostate cancer.

    Published in:
    Cancer (0008543X), 2024, v. 130, n. 21, p. 3671, doi. 10.1002/cncr.35443
    By:
    • Basaria, Shehzad;
    • Taplin, Mary‐Ellen;
    • McDonnell, Marie;
    • Simonson, Donald C.;
    • Lin, Alexander P.;
    • Dufour, Alyssa B.;
    • Habtemariam, Daniel;
    • Nguyen, Paul L.;
    • Ravi, Praful;
    • Kibel, Adam S.;
    • Sweeney, Christopher J.;
    • D'Amico, Anthony V.;
    • Roberts, Daniel A.;
    • Xu, Wenxin;
    • Wei, Xiao X.;
    • Sunkara, Rajitha;
    • Choudhury, Atish D.;
    • Mantia, Charlene;
    • Beltran, Himisha;
    • Pomerantz, Mark
    Publication type:
    Article
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    A phase I/II study of rovalpituzumab tesirine in delta-like 3—expressing advanced solid tumors.

    Published in:
    NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00214-y
    By:
    • Mansfield, Aaron S.;
    • Hong, David S.;
    • Hann, Christine L.;
    • Farago, Anna F.;
    • Beltran, Himisha;
    • Waqar, Saiama N.;
    • Hendifar, Andrew E.;
    • Anthony, Lowell B.;
    • Taylor, Matthew H.;
    • Bryce, Alan H.;
    • Tagawa, Scott T.;
    • Lewis, Karl;
    • Niu, Jiaxin;
    • Chung, Christine H.;
    • Cleary, James M.;
    • Rossi, Michael;
    • Ludwig, Carrianne;
    • Valenzuela, Ricardo;
    • Luo, Yan;
    • Aggarwal, Rahul
    Publication type:
    Article
    25

    Molecular features of prostate cancer after neoadjuvant therapy in the phase 3 CALGB 90203 trial.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2024, v. 116, n. 1, p. 115, doi. 10.1093/jnci/djad184
    By:
    • Sumiyoshi, Takayuki;
    • Wang, Xiaofei;
    • Warner, Evan W;
    • Sboner, Andrea;
    • Annala, Matti;
    • Sigouros, Michael;
    • Beja, Kevin;
    • Mizuno, Kei;
    • Ku, Shengyu;
    • Fazli, Ladan;
    • Eastham, James;
    • Taplin, Mary-Ellen;
    • Simko, Jeffrey;
    • Halabi, Susan;
    • Morris, Michael J;
    • Gleave, Martin E;
    • Wyatt, Alexander W;
    • Beltran, Himisha
    Publication type:
    Article
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    CD38 is methylated in prostate cancer and regulates extracellular NAD<sup>+</sup>.

    Published in:
    Cancer & Metabolism, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40170-018-0186-3
    By:
    • Mottahedeh, Jack;
    • Haffner, Michael C.;
    • Grogan, Tristan R.;
    • Hashimoto, Takao;
    • Crowell, Preston D.;
    • Beltran, Himisha;
    • Sboner, Andrea;
    • Bareja, Rohan;
    • Esopi, David;
    • Isaacs, William B.;
    • Yegnasubramanian, Srinivasan;
    • Rettig, Matthew B.;
    • Elashoff, David A.;
    • Platz, Elizabeth A.;
    • De Marzo, Angelo M.;
    • Teitell, Michael A.;
    • Goldstein, Andrew S.
    Publication type:
    Article
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    Plasma androgen receptor and serum chromogranin A in advanced prostate cancer.

    Published in:
    Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33774-4
    By:
    • Conteduca, Vincenza;
    • Scarpi, Emanuela;
    • Salvi, Samanta;
    • Casadio, Valentina;
    • Lolli, Cristian;
    • Gurioli, Giorgia;
    • Schepisi, Giuseppe;
    • Wetterskog, Daniel;
    • Farolfi, Alberto;
    • Menna, Cecilia;
    • De Lisi, Delia;
    • Burgio, Salvatore Luca;
    • Beltran, Himisha;
    • Attard, Gerhardt;
    • De Giorgi, Ugo
    Publication type:
    Article
    35

    ERG induces taxane resistance in castration-resistant prostate cancer.

    Published in:
    Nature Communications, 2014, v. 5, n. 11, p. 5548, doi. 10.1038/ncomms6548
    By:
    • Galletti, Giuseppe;
    • Matov, Alexandre;
    • Beltran, Himisha;
    • Fontugne, Jacqueline;
    • Miguel Mosquera, Juan;
    • Cheung, Cynthia;
    • MacDonald, Theresa Y.;
    • Sung, Matthew;
    • O'Toole, Sandra;
    • Kench, James G.;
    • Suk Chae, Sung;
    • Kimovski, Dragi;
    • Tagawa, Scott T.;
    • Nanus, David M.;
    • Rubin, Mark A.;
    • Horvath, Lisa G.;
    • Giannakakou, Paraskevi;
    • Rickman, David S.
    Publication type:
    Article
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    A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer.

    Published in:
    NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00854-4
    By:
    • Nauseef, Jones T.;
    • Chu, Timothy R.;
    • Hooper, William F.;
    • Alonso, Alicia;
    • Oku, Ali;
    • Geiger, Heather;
    • Goldstein, Zoe R.;
    • Shah, Minita;
    • Sigouros, Michael;
    • Manohar, Jyothi;
    • Steinsnyder, Zoe;
    • Winterkorn, Lara;
    • Robinson, Brian D.;
    • Sboner, Andrea;
    • Beltran, Himisha;
    • Elemento, Olivier;
    • Hajirasouliha, Iman;
    • Imielinski, Marcin;
    • Nanus, David M.;
    • Tagawa, Scott T.
    Publication type:
    Article
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    Unraveling the clonal hierarchy of somatic genomic aberrations.

    Published in:
    Genome Biology, 2014, v. 15, n. 8, p. 1, doi. 10.1186/s13059-014-0439-6
    By:
    • Prandi, Davide;
    • Baca, Sylvan C.;
    • Romanel, Alessandro;
    • Barbieri, Christopher E.;
    • Mosquera, Juan Miguel;
    • Fontugne, Jacqueline;
    • Beltran, Himisha;
    • Sboner, Andrea;
    • Garraway, Levi A.;
    • Rubin, Mark A.;
    • Demichelis, Francesca
    Publication type:
    Article
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    Plasma tumor DNA is associated with increased risk of venous thromboembolism in metastatic castration‐resistant cancer patients.

    Published in:
    International Journal of Cancer, 2022, v. 150, n. 7, p. 1166, doi. 10.1002/ijc.33834
    By:
    • Conteduca, Vincenza;
    • Scarpi, Emanuela;
    • Wetterskog, Daniel;
    • Brighi, Nicole;
    • Ferroni, Fabio;
    • Rossi, Alice;
    • Romanel, Alessandro;
    • Gurioli, Giorgia;
    • Bleve, Sara;
    • Gianni, Caterina;
    • Schepisi, Giuseppe;
    • Lolli, Cristian;
    • Cortesi, Pietro;
    • Matteucci, Federica;
    • Barone, Domenico;
    • Paganelli, Giovanni;
    • Demichelis, Francesca;
    • Beltran, Himisha;
    • Attard, Gerhardt;
    • De Giorgi, Ugo
    Publication type:
    Article
    46

    Common germline-somatic variant interactions in advanced urothelial cancer.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19971-8
    By:
    • Vosoughi, Aram;
    • Zhang, Tuo;
    • Shohdy, Kyrillus S.;
    • Vlachostergios, Panagiotis J.;
    • Wilkes, David C.;
    • Bhinder, Bhavneet;
    • Tagawa, Scott T.;
    • Nanus, David M.;
    • Molina, Ana M.;
    • Beltran, Himisha;
    • Sternberg, Cora N.;
    • Motanagh, Samaneh;
    • Robinson, Brian D.;
    • Xiang, Jenny;
    • Fan, Xiao;
    • Chung, Wendy K.;
    • Rubin, Mark A.;
    • Elemento, Olivier;
    • Sboner, Andrea;
    • Mosquera, Juan Miguel
    Publication type:
    Article
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    Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF SELECT consortium assay.

    Published in:
    NAR Cancer, 2022, v. 4, n. 2, p. 1, doi. 10.1093/narcan/zcac016
    By:
    • Orlando, Francesco;
    • Romanel, Alessandro;
    • Trujillo, Blanca;
    • Sigouros, Michael;
    • Wetterskog, Daniel;
    • Quaini, Orsetta;
    • Leone, Gianmarco;
    • Xiang, Jenny Z.;
    • Wingate, Anna;
    • Tagawa, Scott;
    • Jayaram, Anuradha;
    • Linch, Mark;
    • Jamal-Hanjani, Mariam;
    • Swanton, Charles;
    • Rubin, Mark A.;
    • Wyatt, Alexander W.;
    • Beltran, Himisha;
    • Attard, Gerhardt;
    • Demichelis, Francesca
    Publication type:
    Article