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Synthetic Aminoglycosides Efficiently Suppress Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations and Are Enhanced by Ivacaftor.
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- American Journal of Respiratory Cell & Molecular Biology, 2014, v. 50, n. 4, p. 805, doi. 10.1165/rcmb.2013-0282OC
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- Article
Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity against Bacillus anthracis and Inhibition of Anthrax Lethal FactorWe thank Dr. Abed Atmana (The Triangle Research and Development Center, Kfar-Qaraa) for antibacterial tests and insightful discussions. This research was supported by the Israel Science Foundation founded by the Israel Academy of Sciences and Humanities (Grant no.: 766/04), and in part by the L. and L. Richmond Fund for Promotion of Research at the Technion and by the National Institutes of Health (C.H.W.). V.B. acknowledges the financial support of the Center of Absorption in Science, the Ministry of Immigration Absorption, and the Ministry of Science and Arts, Israel (Kamea Program).
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- Angewandte Chemie, 2005, v. 117, n. 3, p. 451, doi. 10.1002/ange.200462003
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- Article
Towards a new class of synthetic antibacterials acting on lipopolysaccharide biosynthesis.
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- Drug Development Research, 2000, v. 50, n. 3/4, p. 416, doi. 10.1002/1098-2299(200007/08)50:3/4<416::AID-DDR24>3.0.CO;2-G
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- Article
Family of Thiomercuric Derivatives of Sugars: Synthesis, Fungicidal/Herbicidal Activity, and Application to the X-Ray Structure Determination of the Corresponding Enzymes.
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- Israel Journal of Chemistry, 2000, v. 40, n. 3/4, p. 177, doi. 10.1560/E8DM-02PK-DL0V-U7FR
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- Article
A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation.
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- EMBO Molecular Medicine, 2012, v. 4, n. 11, p. 1186, doi. 10.1002/emmm.201201438
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- Article
Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression.
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- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060478
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- Article
Preliminary crystallographic analysis of Xyn52B2, a GH52 β-D-xylosidase from Geobacillus stearothermophilus T6.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 12, p. 1675, doi. 10.1107/S2053230X14023887
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Crystal structure and snapshots along the reaction pathway of a family 51 a-L-arabinofuranosidase.
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- EMBO Journal, 2003, v. 22, n. 19, p. 4922, doi. 10.1093/emboj/cdg494
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- Article
Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics.
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- Nucleic Acids Research, 2015, v. 43, n. 17, p. 8601, doi. 10.1093/nar/gkv821
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- Article
Towards Catalytic Antibiotics: Redesign of Aminoglycosides To Catalytically Disable Bacterial Ribosomes.
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- ChemBioChem, 2019, v. 20, n. 2, p. 247, doi. 10.1002/cbic.201800549
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Erratum to: Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model.
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- 2013
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- Correction notice
Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54.
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- Journal of Molecular Medicine, 2011, v. 89, n. 11, p. 1149, doi. 10.1007/s00109-011-0787-6
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- Article
Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model.
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- Journal of Molecular Medicine, 2011, v. 89, n. 4, p. 389, doi. 10.1007/s00109-010-0704-4
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- Article
Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity against Bacillus anthracis and Inhibition of Anthrax Lethal FactorWe thank Dr. Abed Atmana (The Triangle Research and Development Center, Kfar-Qaraa) for antibacterial tests and insightful discussions. This research was supported by the Israel Science Foundation founded by the Israel Academy of Sciences and Humanities (Grant no.: 766/04), and in part by the L. and L. Richmond Fund for Promotion of Research at the Technion and by the National Institutes of Health (C.H.W.). V.B. acknowledges the financial support of the Center of Absorption in Science, the Ministry of Immigration Absorption, and the Ministry of Science and Arts, Israel (Kamea Program).
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 3, p. 447, doi. 10.1002/anie.200462003
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- Article
The identification of the acid–base catalyst of α-arabinofuranosidase from Geobacillus stearothermophilus T-6, a family 51 glycoside hydrolase
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- FEBS Letters, 2002, v. 514, n. 2/3, p. 163, doi. 10.1016/S0014-5793(02)02343-8
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- Article