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Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3118, doi. 10.3390/ijms23063118
By:
- Romero-Picó, Amparo;
- Novelle, Marta G.;
- Al-Massadi, Omar;
- Beiroa, Daniel;
- Tojo, Marta;
- Heras, Violeta;
- Ruiz-Pino, Francisco;
- Senra, Ana;
- López, Miguel;
- Blouet, Clemence;
- Tena-Sempere, Manuel;
- Nogueiras, Rubén;
- Diéguez, Carlos
Publication type:
Article
Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.59258
By:
- Crespo, María;
- Gonzalez-Teran, Barbara;
- Nikolic, Ivana;
- Mora, Alfonso;
- Folgueira, Cintia;
- Rodríguez, Elena;
- Leiva-Vega, Luis;
- Pintor-Chocano, Aránzazu;
- Fernández-Chacón, Macarena;
- Ruiz-Garrido, Irene;
- Cicuéndez, Beatriz;
- Tomás-Loba, Antonia;
- A.-Gonzalez, Noelia;
- Caballero-Molano, Ainoa;
- Beiroa, Daniel;
- Hernández-Cosido, Lourdes;
- Torres, Jorge L.;
- Kennedy, Norman J.;
- Davis, Roger J.;
- Benedito, Rui
Publication type:
Article
Oral Pharmacological Activation of Hypothalamic Guanylate Cyclase 2C Receptor Stimulates Brown Fat Thermogenesis to Reduce Body Weight.
Published in:
Neuroendocrinology, 2020, v. 110, n. 11/12, p. 1042, doi. 10.1159/000505972
By:
- Folgueira, Cintia;
- Torres-Leal, Francisco Leonardo;
- Beiroa, Daniel;
- Pena-León, Verónica;
- Da Silva Lima, Natália;
- Milbank, Edward;
- Senra, Ana;
- Al-Massadi, Omar;
- López, Miguel;
- Diéguez, Carlos;
- Seoane, Luisa M.;
- Nogueiras, Rubén
Publication type:
Article
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25390-0
By:
- Gonzalez-Rellan, Maria J.;
- Fondevila, Marcos F.;
- Fernandez, Uxia;
- Rodríguez, Amaia;
- Varela-Rey, Marta;
- Veyrat-Durebex, Christelle;
- Seoane, Samuel;
- Bernardo, Ganeko;
- Lopitz-Otsoa, Fernando;
- Fernández-Ramos, David;
- Bilbao, Jon;
- Iglesias, Cristina;
- Novoa, Eva;
- Ameneiro, Cristina;
- Senra, Ana;
- Beiroa, Daniel;
- Cuñarro, Juan;
- DP Chantada-Vazquez, Maria;
- Garcia-Vence, Maria;
- Bravo, Susana B.
Publication type:
Article
p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.
Published in:
PLoS Biology, 2018, p. 1, doi. 10.1371/journal.pbio.2004455
By:
- Matesanz, Nuria;
- Nikolic, Ivana;
- Leiva, Magdalena;
- Pulgarín-Alfaro, Marta;
- Santamans, Ayelén M.;
- Bernardo, Edgar;
- Mora, Alfonso;
- Herrera-Melle, Leticia;
- Rodríguez, Elena;
- Beiroa, Daniel;
- Caballero, Ainoa;
- Martín-García, Elena;
- Acín-Pérez, Rebeca;
- Hernández-Cosido, Lourdes;
- Leiva-Vega, Luis;
- Torres, Jorge L.;
- Centeno, Francisco;
- Nebreda, Angel R.;
- Enríquez, José Antonio;
- Nogueiras, Rubén
Publication type:
Article
Heterozygous Deficiency of Endoglin Decreases Insulin and Hepatic Triglyceride Levels during High Fat Diet.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054591
By:
- Beiroa, Daniel;
- Romero-Picó, Amparo;
- Langa, Carmen;
- Bernabeu, Carmelo;
- López, Miguel;
- López-Novoa, José M.;
- Nogueiras, Ruben;
- Diéguez, Carlos
Publication type:
Article
Action of Obestatin in Skeletal Muscle Repair: Stem Cell Expansion, Muscle Growth, and Microenvironment Remodeling.
Published in:
Molecular Therapy, 2015, v. 23, n. 6, p. 1003, doi. 10.1038/mt.2015.40
By:
- Gurriarán-Rodríguez, Uxía;
- Santos-Zas, Icía;
- González-Sánchez, Jessica;
- Beiroa, Daniel;
- Moresi, Viviana;
- Mosteiro, Carlos S;
- Lin, Wei;
- Viñuela, Juan E;
- Señarís, José;
- García-Caballero, Tomás;
- Casanueva, Felipe F;
- Nogueiras, Rubén;
- Gallego, Rosalía;
- Renaud, Jean-Marc;
- Adamo, Sergio;
- Pazos, Yolanda;
- Camiña, Jesús P
Publication type:
Article
Adipose tissue is a key organ for the beneficial effects of GLP‐2 metabolic function.
Published in:
British Journal of Pharmacology, 2021, v. 178, n. 10, p. 2131, doi. 10.1111/bph.15278
By:
- Ejarque, Miriam;
- Sabadell‐Basallote, Joan;
- Beiroa, Daniel;
- Calvo, Enrique;
- Keiran, Noelia;
- Nuñez‐Roa, Catalina;
- Rodríguez, Maria del Mar;
- Sabench, Fatima;
- Castillo, Daniel;
- Jimenez, Veronica;
- Bosch, Fatima;
- Nogueiras, Ruben;
- Vendrell, Joan;
- Fernández‐Veledo, Sonia
Publication type:
Article
LEAP-2 Counteracts Ghrelin-Induced Food Intake in a Nutrient, Growth Hormone and Age Independent Manner.
Published in:
Cells (2073-4409), 2022, v. 11, n. 3, p. 324, doi. 10.3390/cells11030324
By:
- Lugilde, Javier;
- Casado, Sabela;
- Beiroa, Daniel;
- Cuñarro, Juan;
- Garcia-Lavandeira, Montserrat;
- Álvarez, Clara V.;
- Nogueiras, Rubén;
- Diéguez, Carlos;
- Tovar, Sulay
Publication type:
Article
p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05711-6
By:
- Quiñones, Mar;
- Al-Massadi, Omar;
- Folgueira, Cintia;
- Bremser, Stephan;
- Gallego, Rosalía;
- Torres-Leal, Leonardo;
- Haddad-Tóvolli, Roberta;
- García-Caceres, Cristina;
- Hernandez-Bautista, Rene;
- Lam, Brian Y. H.;
- Beiroa, Daniel;
- Sanchez-Rebordelo, Estrella;
- Senra, Ana;
- Malagon, Jose A.;
- Valerio, Patricia;
- Fondevila, Marcos F.;
- Fernø, Johan;
- Malagon, Maria M.;
- Contreras, Raian;
- Pfluger, Paul
Publication type:
Article
Antiobesity effects of intestinal gluconeogenesis are mediated by the brown adipose tissue sympathetic nervous system.
Published in:
Obesity (19307381), 2024, v. 32, n. 4, p. 710, doi. 10.1002/oby.23985
By:
- Vily‐Petit, Justine;
- Soty‐Roca, Maud;
- Silva, Marine;
- Micoud, Manon;
- Evrard, Félicie;
- Bron, Clara;
- Raffin, Margaux;
- Beiroa, Daniel;
- Nogueiras, Rubén;
- Roussel, Damien;
- Gautier‐Stein, Amandine;
- Rajas, Fabienne;
- Cota, Daniela;
- Mithieux, Gilles
Publication type:
Article
Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19489-z
By:
- Rodríguez-Fdez, Sonia;
- Lorenzo-Martín, L. Francisco;
- Fernández-Pisonero, Isabel;
- Porteiro, Begoña;
- Veyrat-Durebex, Christelle;
- Beiroa, Daniel;
- Al-Massadi, Omar;
- Abad, Antonio;
- Diéguez, Carlos;
- Coppari, Roberto;
- Nogueiras, Rubén;
- Bustelo, Xosé R.
Publication type:
Article
Antiobesity efficacy of GLP-1 receptor agonist liraglutide is associated with peripheral tissue-specific modulation of lipid metabolic regulators.
Published in:
Biofactors, 2016, v. 42, n. 6, p. 600, doi. 10.1002/biof.1295
By:
- Decara, Juan;
- Arrabal, Sergio;
- Beiroa, Daniel;
- Rivera, Patricia;
- Vargas, Antonio;
- Serrano, Antonia;
- Pavón, Francisco Javier;
- Ballesteros, Joan;
- Dieguez, Carlos;
- Nogueiras, Rubén;
- Rodríguez de Fonseca, Fernando;
- Suárez, Juan
Publication type:
Article
Uroguanylin Improves Leptin Responsiveness in Diet-Induced Obese Mice.
Published in:
Nutrients, 2019, v. 11, n. 4, p. 752, doi. 10.3390/nu11040752
By:
- Folgueira, Cintia;
- Beiroa, Daniel;
- González-Rellán, María Jesús;
- Porteiro, Begoña;
- Milbank, Edward;
- Castelao, Cecilia;
- García-Palacios, María;
- Casanueva, Felipe F;
- López, Miguel;
- Diéguez, Carlos;
- Seoane, Luisa M.;
- Nogueiras, Rubén
Publication type:
Article
MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance.
Published in:
2019
By:
- Al-Massadi, Omar;
- Quiñones, Mar;
- Clasadonte, Jerome;
- Hernandez-Bautista, René;
- Romero-Picó, Amparo;
- Folgueira, Cintia;
- Morgan, Donald A.;
- Kalló, Imre;
- Heras, Violeta;
- Senra, Ana;
- Funderburk, Samuel C.;
- Krashes, Michael J.;
- Souto, Yara;
- Fidalgo, Miguel;
- Luquet, Serge;
- Chee, Melissa J.;
- Imbernon, Monica;
- Beiroa, Daniel;
- García-Caballero, Lucía;
- Gallego, Rosalia
Publication type:
journal article
SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity.
Published in:
2018
By:
- Seoane-Collazo, Patricia;
- Roa, Juan;
- Rial-Pensado, Eva;
- Liñares-Pose, Laura;
- Beiroa, Daniel;
- Ruíz-Pino, Francisco;
- López-González, Tania;
- Morgan, Donald A.;
- Pardavila, José Ángel;
- Sánchez-Tapia, María Jesús;
- Martínez-Sánchez, Noelia;
- Contreras, Cristina;
- Fidalgo, Miguel;
- Diéguez, Carlos;
- Coppari, Roberto;
- Rahmouni, Kamal;
- Nogueiras, Rubén;
- Tena-Sempere, Manuel;
- López, Miguel
Publication type:
journal article
Uroguanylin Action in the Brain Reduces Weight Gain in Obese Mice via Different Efferent Autonomic Pathways.
Published in:
2016
By:
- Folgueira, Cintia;
- Beiroa, Daniel;
- Callon, Aurelie;
- Al-Massadi, Omar;
- Barja-Fernandez, Silvia;
- Senra, Ana;
- Fernø, Johan;
- López, Miguel;
- Dieguez, Carlos;
- Casanueva, Felipe F.;
- Rohner-Jeanrenaud, Françoise;
- Seoane, Luisa M.;
- Nogueiras, Ruben
Publication type:
journal article
GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK.
Published in:
Diabetes, 2014, v. 63, n. 10, p. 3346, doi. 10.2337/db14-0302
By:
- Beiroa, Daniel;
- Imbernon, Monica;
- Gallego, Rosalía;
- Senra, Ana;
- Herranz, Daniel;
- Villarroya, Francesc;
- Serrano, Manuel;
- Fernø, Johan;
- Salvador, Javier;
- Escalada, Javier;
- Dieguez, Carlos;
- Lopez, Miguel;
- Frühbeck, Gema;
- Nogueiras, Ruben
Publication type:
Article

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