Works by Behar, Samuel M.

Results: 31

In search of a new paradigm for protective immunity to TB.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 4, p. 289, doi. 10.1038/nrmicro3230

By:

Nunes-Alves, Cláudio;
Booty, Matthew G.;
Carpenter, Stephen M.;
Jayaraman, Pushpa;
Rothchild, Alissa C.;
Behar, Samuel M.

Publication type:

Article

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 9, p. 668, doi. 10.1038/nrmicro2387

By:

Behar, Samuel M.;
Divangahi, Maziar;
Remold, Heinz G.

Publication type:

Article

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65109

By:

Kiritsy, Michael C.;
McCann, Katelyn;
Mott, Daniel;
Holland, Steven M.;
Behar, Samuel M.;
Sassetti, Christopher M.;
Olive, Andrew J.

Publication type:

Article

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection.

Published in:

PLoS Pathogens, 2016, v. 12, n. 3, p. 1, doi. 10.1371/journal.ppat.1005490

By:

Jayaraman, Pushpa;
Jacques, Miye K.;
Zhu, Chen;
Steblenko, Katherine M.;
Stowell, Britni L.;
Madi, Asaf;
Anderson, Ana C.;
Kuchroo, Vijay K.;
Behar, Samuel M.

Publication type:

Article

A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis.

Published in:

PLoS Pathogens, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.ppat.1005380

By:

Carpenter, Stephen M.;
Nunes-Alves, Cláudio;
Booty, Matthew G.;
Way, Sing Sing;
Behar, Samuel M.

Publication type:

Article

Heterogeneity in lung macrophage control of Mycobacterium tuberculosis is modulated by T cells.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48515-7

By:

Lai, Rocky;
Williams, Travis;
Rakib, Tasfia;
Lee, Jinhee;
Behar, Samuel M.

Publication type:

Article

Alpha-galactosylceramide as a therapeutic agent for pulmonary Mycobacterium tuberculosis infection.

Published in:

2010

By:

Sada-Ovalle I;
Sköld M;
Tian T;
Besra GS;
Behar SM;
Sada-Ovalle, Isabel;
Sköld, Markus;
Tian, Tian;
Besra, Gurdyal S;
Behar, Samuel M

Publication type:

journal article

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response.

Published in:

PLoS Pathogens, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.ppat.1009000

By:

Sutiwisesak, Rujapak;
Hicks, Nathan D.;
Boyce, Shayla;
Murphy, Kenan C.;
Papavinasasundaram, Kadamba;
Carpenter, Stephen M.;
Boucau, Julie;
Joshi, Neelambari;
Le Gall, Sylvie;
Fortune, Sarah M.;
Sassetti, Christopher M.;
Behar, Samuel M.

Publication type:

Article

CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis.

Published in:

PLoS Pathogens, 2020, v. 16, n. 6, p. 1, doi. 10.1371/journal.ppat.1008621

By:

Lee, Jinhee;
Boyce, Shayla;
Powers, Jennifer;
Baer, Christina;
Sassetti, Christopher M.;
Behar, Samuel M.

Publication type:

Article

Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis).

Published in:

BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08867-0

By:

Jaiswal, Swati;
Nyquist, Sarah K.;
Boyce, Shayla;
Jivanjee, Tasneem;
Ibrahim, Samira;
Bromley, Joshua D.;
Gatter, G. James;
Gideon, Hannah;
Patel, Kush;
Ganchua, Sharie Keanne;
Berger, Bonnie;
Fortune, Sarah M.;
Flynn, JoAnne L.;
Shalek, Alex K.;
Behar, Samuel M.

Publication type:

Article

Immunology: Fixing the odds against tuberculosis.

Published in:

Nature, 2014, v. 511, n. 7507, p. 39, doi. 10.1038/nature13512

By:

Behar, Samuel M.;
Sassetti, Christopher M.

Publication type:

Article

CD4 T cell dysfunction is associated with bacterial recrudescence during chronic tuberculosis.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57819-1

By:

Chang, Evelyn;
Cavallo, Kelly;
Behar, Samuel M.

Publication type:

Article

Expansions of Vα12 CD8+ T-Cells in Rheumatoid Arthritisa.

Published in:

Annals of the New York Academy of Sciences, 1995, v. 756, n. 1, p. 130, doi. 10.1111/j.1749-6632.1995.tb44498.x

By:

BEHAR, SAMUEL M.;
ROY, CHRIS;
BRENNER, MICHAEL B.

Publication type:

Article

Characterization of guinea-pig group 1 CD1 proteins.

Published in:

Immunology, 2002, v. 106, n. 2, p. 159, doi. 10.1046/j.1365-2567.2002.01422.x

By:

Hiromatsu, Kenji;
Dascher, Christopher C;
Sugita, Masahiko;
Gingrich-Baker, Cindy;
Behar, Samuel M;
LeClair, Kenneth P;
Brenner, Michael B;
Porcelli, Steven A

Publication type:

Article

The Molecular Origin of Anti-DNA Antibodies.

Published in:

International Reviews of Immunology, 1989, v. 5, n. 1, p. 23, doi. 10.3109/08830188909086988

By:

Behar, Samuel M.;
Corbet, Sylvie;
Diamond, Betty;
Scharff, Matthew D.

Publication type:

Article

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection.

Published in:

PLoS Pathogens, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.ppat.1004849

By:

Nunes-Alves, Cláudio;
Booty, Matthew G.;
Carpenter, Stephen M.;
Rothchild, Alissa C.;
Martin, Constance J.;
Desjardins, Danielle;
Steblenko, Katherine;
Kløverpris, Henrik N.;
Madansein, Rajhmun;
Ramsuran, Duran;
Leslie, Alasdair;
Correia-Neves, Margarida;
Behar, Samuel M.

Publication type:

Article

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis.

Published in:

PLoS Pathogens, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.ppat.1003805

By:

Rothchild, Alissa C.;
Jayaraman, Pushpa;
Nunes-Alves, Cláudio;
Behar, Samuel M.

Publication type:

Article

EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity.

Published in:

PLoS Pathogens, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.ppat.1000957

By:

Garces, Alejandra;
Atmakuri, Krishnamohan;
Chase, Michael R.;
Woodworth, Joshua S.;
Krastins, Bryan;
Rothchild, Alissa C.;
Ramsdell, Talia L.;
Lopez, Mary F.;
Behar, Samuel M.;
Sarracino, David A.;
Fortune, Sarah M.

Publication type:

Article

Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis-Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria.

Published in:

PLoS Pathogens, 2008, v. 4, n. 12, p. 1, doi. 10.1371/journal.ppat.1000239

By:

Sada-Ovalle, Isabel;
Chiba, Asako;
Gonzales, Adaena;
Brenner, Michael B.;
Behar, Samuel M.

Publication type:

Article

Tissue resident-like CD4+ T cells secreting IL-17 control Mycobacteria tuberculosis in the human lung.

Published in:

Journal of Clinical Investigation, 2021, v. 131, n. 10, p. 1, doi. 10.1172/jci142014

By:

Ogongo, Paul;
Tezera, Liku B.;
Ardain, Amanda;
Nhamoyebonde, Shepherd;
Ramsuran, Duran;
Singh, Alveera;
Ng'oepe, Abigail;
Karim, Farina;
Taryn Naidoo;
Khan, Khadija;
Dullabh, Kaylesh J.;
Fehlings, Michael;
Heng Lee, Boon;
Nardin, Alessandra;
Arlehamn, Cecilia S. Lindestam;
Sette, Alessandro;
Behar, Samuel M.;
Steyn, Adrie J. C.;
Madansein, Rajhmun;
Kløverpris, Henrik N.

Publication type:

Article

Somatic Diversification of Anti-DNA Antibodies.

Published in:

Annals of the New York Academy of Sciences, 1988, v. 546, n. 1, p. 188, doi. 10.1111/j.1749-6632.1988.tb21634.x

By:

BEHAR, SAMUEL M.;
SCHARFF, MATTHEW D.

Publication type:

Article

IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection.

Published in:

Scientific Reports, 2016, p. 36720, doi. 10.1038/srep36720

By:

Booty, Matthew G.;
Barreira-Silva, Palmira;
Carpenter, Stephen M.;
Nunes-Alves, Cláudio;
Jacques, Miye K.;
Stowell, Britni L.;
Jayaraman, Pushpa;
Beamer, Gillian;
Behar, Samuel M.

Publication type:

Article

Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages.

Published in:

PLoS Pathogens, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.ppat.1007060

By:

Yang, Jason D.;
Mott, Daniel;
Sutiwisesak, Rujapak;
Lu, Yu-Jung;
Raso, Fiona;
Stowell, Britni;
Babunovic, Greg Hunter;
Lee, Jinhee;
Carpenter, Steve M.;
Way, Sing Sing;
Fortune, Sarah M.;
Behar, Samuel M.

Publication type:

Article

Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis.

Published in:

PLoS Pathogens, 2017, v. 13, n. 11, p. 1, doi. 10.1371/journal.ppat.1006704

By:

Carpenter, Stephen M.;
Yang, Jason D.;
Lee, Jinhee;
Barreira-Silva, Palmira;
Behar, Samuel M.

Publication type:

Article

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.

Published in:

Nature Immunology, 2010, v. 11, n. 8, p. 751, doi. 10.1038/ni.1904

By:

Divangahi, Maziar;
Desjardins, Danielle;
Nunes-Alves, Cláudio;
Remold, Heinz G.;
Behar, Samuel M.

Publication type:

Article

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.

Published in:

Nature Immunology, 2009, v. 10, n. 8, p. 899, doi. 10.1038/ni.1758

By:

Divangahi, Maziar;
Minjian Chen;
Huixian Gan;
Desjardins, Danielle;
Hickman, Tyler T.;
Lee, David M.;
Fortune, Sarah;
Behar, Samuel M.;
Remold, Heinz G.

Publication type:

Article

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.

Published in:

Nature Immunology, 2006, v. 7, n. 9, p. 978, doi. 10.1038/ni1380

By:

Kinjo, Yuki;
Tupin, Emmanuel;
Wu, Douglass;
Fujio, Masakazu;
Garcia-Navarro, Raquel;
Benhnia, Mohammed Rafii-El-Idrissi;
Zajonc, Dirk M;
Ben-Menachem, Gil;
Ainge, Gary D;
Painter, Gavin F;
Khurana, Archana;
Hoebe, Kasper;
Behar, Samuel M;
Beutler, Bruce;
Wilson, Ian A;
Tsuji, Moriya;
Sellati, Timothy J;
Chi-Huey Wong;
Kronenberg, Mitchell

Publication type:

Article

IFNγ and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on Mycobacterium avium -Induced Thymic Atrophy.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.696415

By:

Barreira-Silva, Palmira;
Melo-Miranda, Rita;
Nobrega, Claudia;
Roque, Susana;
Serre-Miranda, Cláudia;
Borges, Margarida;
Armada, Gisela;
de Sá Calçada, Daniela;
Behar, Samuel M.;
Appelberg, Rui;
Correia-Neves, Margarida

Publication type:

Article

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.

Published in:

2020

By:

Ogongo, Paul;
Steyn, Adrie J. C.;
Karim, Farina;
Dullabh, Kaylesh J.;
Awala, Ismael;
Madansein, Rajhmun;
Leslie, Alasdair;
Behar, Samuel M.;
Steyn, Adrie Jc

Publication type:

journal article

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.

Published in:

Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 214, doi. 10.1172/JCI130711

By:

Ogongo, Paul;
Steyn, Adrie J. C.;
Karim, Farina;
Dullabh, Kaylesh J.;
Awala, Ismael;
Madansein, Rajhmun;
Leslie, Alasdair;
Behar, Samuel M.

Publication type:

Article

Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.

Published in:

2010

By:

Zeissig, Sebastian;
Dougan, Stephanie K.;
Barral, Duarte C.;
Junker, Yvonne;
Zhangguo Chen;
Kaser, Arthur;
Ho, Madelyn;
Mandel, Hannah;
McIntyre, Adam;
Kennedy, Susan M.;
Painter, Gavin F.;
Veerapen, Natacha;
Besra, Gurdyal S.;
Cerundolo, Vincenzo;
Simon Yue;
Beladi, Sarah;
Behar, Samuel M.;
Xiuxu Chen;
Gumperz, Jenny E.;
Breckpot, Karine

Publication type:

journal article

Works by Behar, Samuel M.

In search of a new paradigm for protective immunity to TB.

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells.

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection.

A Higher Activation Threshold of Memory CD8<sup>+</sup> T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis.

Heterogeneity in lung macrophage control of Mycobacterium tuberculosis is modulated by T cells.

Alpha-galactosylceramide as a therapeutic agent for pulmonary Mycobacterium tuberculosis infection.

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response.

CD11c<sup>Hi</sup> monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis.

Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis).

Immunology: Fixing the odds against tuberculosis.

CD4 T cell dysfunction is associated with bacterial recrudescence during chronic tuberculosis.

Expansions of Vα12 CD8+ T-Cells in Rheumatoid Arthritis<sup>a</sup>.

Characterization of guinea-pig group 1 CD1 proteins.

The Molecular Origin of Anti-DNA Antibodies.

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection.

iNKT Cell Production of GM-CSF Controls <i>Mycobacterium tuberculosis</i>.

EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity.

Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis-Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria.

Tissue resident-like CD4+ T cells secreting IL-17 control Mycobacteria tuberculosis in the human lung.

Somatic Diversification of Anti-DNA Antibodies.

IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection.

Mycobacterium tuberculosis-specific CD4<sup>+</sup> and CD8<sup>+</sup> T cells differ in their capacity to recognize infected macrophages.

Vaccine-elicited memory CD4<sup>+</sup> T cell expansion is impaired in the lungs during tuberculosis.

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.

IFNγ and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on Mycobacterium avium -Induced Thymic Atrophy.

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.

Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.