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Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.57761
By:
- Annie Wai Yeeng Chai;
- Pei San Yee;
- Price, Stacey;
- Shi Mun Yee;
- Hui Mei Lee;
- Tiong, Vivian K. H.;
- Gonçalves, Emanuel;
- Behan, Fiona M.;
- Bateson, Jessica;
- Gilbert, James;
- Aik Choon Tan;
- McDermott, Ultan;
- Garnett, Mathew J.;
- Sok Ching Cheong
Publication type:
Article
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
Published in:
eLife, 2020, p. 1
By:
- Annie Wai Yeeng Chai;
- Pei San Yee;
- Price, Stacey;
- Shi Mun Yee;
- Hui Mei Lee;
- Tiong, Vivian K. H.;
- Gonçalves, Emanuel;
- Behan, Fiona M.;
- Bateson, Jessica;
- Gilbert, James;
- Tan, Aik Choon;
- McDermott, Ultan;
- Garnett, Mathew J.;
- Sok Ching Cheong
Publication type:
Article
Corrigendum: The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.
Published in:
Scientific Reports, 2016, p. 35330, doi. 10.1038/srep35330
By:
- Duggan, Shane P.;
- Behan, Fiona M.;
- Kirca, Murat;
- Zaheer, Abdul;
- McGarrigle, Sarah A.;
- Reynolds, John V.;
- Vaz, Gisela M. F.;
- Senge, Mathias O.;
- Kelleher, Dermot
Publication type:
Article
The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.
Published in:
Scientific Reports, 2016, p. 32638, doi. 10.1038/srep32638
By:
- Duggan, Shane P.;
- Behan, Fiona M.;
- Kirca, Murat;
- Zaheer, Abdul;
- McGarrigle, Sarah A.;
- Reynolds, John V.;
- Vaz, Gisela M. F.;
- Senge, Mathias O.;
- Kelleher, Dermot
Publication type:
Article
Minimal genome-wide human CRISPR-Cas9 library.
Published in:
Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02268-4
By:
- Gonçalves, Emanuel;
- Thomas, Mark;
- Behan, Fiona M.;
- Picco, Gabriele;
- Pacini, Clare;
- Allen, Felicity;
- Vinceti, Alessandro;
- Sharma, Mamta;
- Jackson, David A.;
- Price, Stacey;
- Beaver, Charlotte M.;
- Dovey, Oliver;
- Parry-Smith, David;
- Iorio, Francesco;
- Parts, Leopold;
- Yusa, Kosuke;
- Garnett, Mathew J.
Publication type:
Article
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09940-1
By:
- Picco, Gabriele;
- Chen, Elisabeth D.;
- Alonso, Luz Garcia;
- Behan, Fiona M.;
- Gonçalves, Emanuel;
- Bignell, Graham;
- Matchan, Angela;
- Fu, Beiyuan;
- Banerjee, Ruby;
- Anderson, Elizabeth;
- Butler, Adam;
- Benes, Cyril H.;
- McDermott, Ultan;
- Dow, David;
- Iorio, Francesco;
- Stronach, Euan;
- Yang, Fengtang;
- Yusa, Kosuke;
- Saez-Rodriguez, Julio;
- Garnett, Mathew J.
Publication type:
Article
Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens.
Published in:
Molecular Systems Biology, 2020, v. 16, n. 7, p. 1, doi. 10.15252/msb.20199405
By:
- Gonçalves, Emanuel;
- Segura‐Cabrera, Aldo;
- Pacini, Clare;
- Picco, Gabriele;
- Behan, Fiona M;
- Jaaks, Patricia;
- Coker, Elizabeth A;
- Meer, Donny;
- Barthorpe, Andrew;
- Lightfoot, Howard;
- Mironenko, Tatiana;
- Beck, Alexandra;
- Richardson, Laura;
- Yang, Wanjuan;
- Lleshi, Ermira;
- Hall, James;
- Tolley, Charlotte;
- Hall, Caitlin;
- Mali, Iman;
- Thomas, Frances
Publication type:
Article
An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-κB activation and cytokine levels.
Published in:
Carcinogenesis, 2010, v. 31, n. 5, p. 936, doi. 10.1093/carcin/bgq036
By:
- Duggan, Shane P.;
- Behan, Fiona M.;
- Kirca, Murat;
- Smith, Sinead;
- Reynolds, John V.;
- Long, Aideen;
- Kelleher, Dermot
Publication type:
Article
Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting.
Published in:
BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-4989-y
By:
- Iorio, Francesco;
- Behan, Fiona M.;
- Gonçalves, Emanuel;
- Bhosle, Shriram G.;
- Chen, Elisabeth;
- Shepherd, Rebecca;
- Beaver, Charlotte;
- Ansari, Rizwan;
- Pooley, Rachel;
- Wilkinson, Piers;
- Harper, Sarah;
- Butler, Adam P.;
- Stronach, Euan A.;
- Saez-Rodriguez, Julio;
- Yusa, Kosuke;
- Garnett, Mathew J.
Publication type:
Article
Structural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects.
Published in:
Genome Biology, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s13059-019-1637-z
By:
- Gonçalves, Emanuel;
- Behan, Fiona M.;
- Louzada, Sandra;
- Arnol, Damien;
- Stronach, Euan A.;
- Yang, Fengtang;
- Yusa, Kosuke;
- Stegle, Oliver;
- Iorio, Francesco;
- Garnett, Mathew J.
Publication type:
Article
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13805-y
By:
- Dempster, Joshua M.;
- Pacini, Clare;
- Pantel, Sasha;
- Behan, Fiona M.;
- Green, Thomas;
- Krill-Burger, John;
- Beaver, Charlotte M.;
- Younger, Scott T.;
- Zhivich, Victor;
- Najgebauer, Hanna;
- Allen, Felicity;
- Gonçalves, Emanuel;
- Shepherd, Rebecca;
- Doench, John G.;
- Yusa, Kosuke;
- Vazquez, Francisca;
- Parts, Leopold;
- Boehm, Jesse S.;
- Golub, Todd R.;
- Hahn, William C.
Publication type:
Article

Found: 11