Found: 23
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Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 8, p. 1779, doi. 10.1007/s11095-022-03194-1
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- Article
Dose response of umeclidinium administered once or twice daily in patients with COPD: a randomised cross-over study.
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- BMC Pulmonary Medicine, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2466-14-2
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- Article
Improved Decision-Making Confidence Using Item-Based Pharmacometric Model: Illustration with a Phase II Placebo-Controlled Trial.
- Published in:
- AAPS Journal, 2021, v. 23, n. 4, p. 1, doi. 10.1208/s12248-021-00600-1
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- Article
A Novel Method for Analysing Frequent Observations from Questionnaires in Order to Model Patient-Reported Outcomes: Application to EXACT® Daily Diary Data from COPD Patients.
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- AAPS Journal, 2019, v. 21, n. 4, p. N.PAG, doi. 10.1208/s12248-019-0319-9
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- Article
Pharmacokinetics of the nitric oxide synthase inhibitor L-N<sup>G</sup>-methylarginine hydrochloride in patients with septic shock<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 1, p. 1, doi. 10.1016/S0009-9236(99)70116-5
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- Article
Inhibition of capsaicin-driven nasal hyper-reactivity by SB-705498, a TRPV1 antagonist.
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- British Journal of Clinical Pharmacology, 2014, v. 77, n. 5, p. 777, doi. 10.1111/bcp.12219
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- Article
Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study.
- Published in:
- BMC Pharmacology & Toxicology, 2013, v. 14, p. 1, doi. 10.1186/2050-6511-14-14
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- Article
Longitudinal Model‐Based Meta‐Analysis of Lung Function Response to Support Phase III Study Design in Chinese Patients With Asthma.
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- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 6, p. 1286, doi. 10.1002/cpt.2578
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- Article
Dose-response modelling of umeclidinium and fluticasone furoate/umeclidinium in asthma.
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- European Journal of Clinical Pharmacology, 2015, v. 71, n. 9, p. 1051, doi. 10.1007/s00228-015-1894-z
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- Article
Losmapimod concentration-QT relationship in healthy volunteers: meta-analysis of data from six clinical trials.
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- European Journal of Clinical Pharmacology, 2013, v. 69, n. 6, p. 1261, doi. 10.1007/s00228-012-1469-1
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- Publication type:
- Article
Power estimation using a population pharmacokinetics model with optimal design by clinical trial simulations: application in pharmacokinetic drug-drug interaction studies.
- Published in:
- European Journal of Clinical Pharmacology, 2011, v. 67, n. 3, p. 225, doi. 10.1007/s00228-010-0957-4
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- Article
The effect of steady-state ropinirole on plasma concentrations of digoxin in patients with Parkinson’s disease.
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- British Journal of Clinical Pharmacology, 1999, v. 47, n. 2, doi. 10.1046/j.1365-2125.1999.00867.x
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- Article
Ranitidine and cimetidine; drug interactions with single dose and steady-state nifedipine administration.
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- British Journal of Clinical Pharmacology, 1987, v. 23, n. 3, p. 311, doi. 10.1111/j.1365-2125.1987.tb03050.x
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- Article
Population Pharmacokinetics of Inhaled Umeclidinium and Vilanterol in Patients with Chronic Obstructive Pulmonary Disease.
- Published in:
- Clinical Pharmacokinetics, 2014, v. 53, n. 7, p. 637, doi. 10.1007/s40262-014-0143-4
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- Article
Population Pharmacokinetics of Losmapimod in Healthy Subjects and Patients with Rheumatoid Arthritis and Chronic Obstructive Pulmonary Diseases.
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- Clinical Pharmacokinetics, 2013, v. 52, n. 3, p. 187, doi. 10.1007/s40262-012-0025-6
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- Article
Dose Response of Umeclidinium Administered Once or Twice Daily in Patients with COPD: A Pooled Analysis of Two Randomized, Double-Blind, Placebo-Controlled Studies.
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- Journal of Clinical Pharmacology, 2014, v. 54, n. 11, p. 1214, doi. 10.1002/jcph.340
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- Publication type:
- Article
Does Short-Term Placebo Response Predict the Long-Term Observation? Meta-Analysis on Forced Expiratory Volume in 1 Second From Asthma Trials.
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- Journal of Clinical Pharmacology, 2014, v. 54, n. 11, p. 1207, doi. 10.1002/jcph.329
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- Article
Joint longitudinal model-based meta-analysis of FEV<sub>1</sub> and exacerbation rate in randomized COPD trials.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 4, p. 297, doi. 10.1007/s10928-023-09853-z
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- Article
Correction to: Bayesian approach to investigate a two-state mixed model of COPD exacerbations.
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- 2019
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- Correction Notice
Bayesian approach to investigate a two-state mixed model of COPD exacerbations.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2019, v. 46, n. 4, p. 371, doi. 10.1007/s10928-019-09643-6
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- Publication type:
- Article
Population model of longitudinal FEV1 data in asthmatics: meta-analysis and predictability of placebo response.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2014, v. 41, n. 6, p. 553, doi. 10.1007/s10928-014-9373-1
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- Article
Pediatric Population Pharmacokinetic Modeling and Exposure–Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data.
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- Journal of Clinical Pharmacology, 2023, v. 63, n. 5, p. 593, doi. 10.1002/jcph.2199
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- Publication type:
- Article
Population Pharmacokinetic Analysis of Fluticasone Furoate/Umeclidinium/Vilanterol via a Single Inhaler in Patients with COPD.
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1461, doi. 10.1002/jcph.1253
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- Publication type:
- Article