Works matching AU Beatch, Gregory N.

Results: 14

Azetukalner, a Novel K<sub>V</sub>7 Potassium Channel Opener, in Adults With Major Depressive Disorder: A Randomized Clinical Trial.

Published in:

JAMA Network Open, 2025, v. 8, n. 5, p. e2514278, doi. 10.1001/jamanetworkopen.2025.14278

By:

Butterfield, Noam N.;
Luzon Rosenblut, Constanza;
Fava, Maurizio;
Correll, Christoph U.;
Rothschild, Anthony J.;
Murrough, James W.;
Mathew, Sanjay J.;
Beatch, Gregory N.;
Grayson, Celene;
Harden, Cynthia;
Qian, Jenny;
McIntosh, Joe;
Namdari, Rostam;
Kenney, Christopher

Publication type:

Article

TMS as a pharmacodynamic indicator of cortical activity of a novel anti‐epileptic drug, XEN1101.

Published in:

Annals of Clinical & Translational Neurology, 2019, v. 6, n. 11, p. 2164, doi. 10.1002/acn3.50896

By:

Premoli, Isabella;
Rossini, Pierre G.;
Goldberg, Paul Y.;
Posadas, Kristina;
Green, Louise;
Yogo, Noah;
Pimstone, Simon;
Abela, Eugenio;
Beatch, Gregory N.;
Richardson, Mark P.

Publication type:

Article

Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy: A Phase 2b Randomized Clinical Trial.

Published in:

JAMA Neurology, 2023, v. 80, n. 11, p. 1145, doi. 10.1001/jamaneurol.2023.3542

By:

French, Jacqueline A.;
Porter, Roger J.;
Perucca, Emilio;
Brodie, Martin J.;
Rogawski, Michael A.;
Pimstone, Simon;
Aycardi, Ernesto;
Harden, Cynthia;
Qian, Jenny;
Luzon Rosenblut, Constanza;
Kenney, Christopher;
Beatch, Gregory N.

Publication type:

Article

Effects of Optical Enantiomers Ck-4000(S) and CK 4001(R) on Defibrillation and Enhancement of Shock- Induced Extension of Action Potential Duration.

Published in:

Journal of Cardiovascular Electrophysiology, 1995, v. 6, n. 9, p. 716, doi. 10.1111/j.1540-8167.1995.tb00448.x

By:

Beatch, Gregory N.;
Dickenson, David R.;
Tang, Anthony S.-L.

Publication type:

Article

RSD1235 blocks late I <sub>Na</sub> and suppresses early afterdepolarizations and torsades de pointes induced by class III agents

Published in:

Cardiovascular Research, 2006, v. 70, n. 3, p. 486, doi. 10.1016/j.cardiores.2006.01.026

By:

Orth, Peter M.R.;
Hesketh, J. Christian;
Mak, Carmen K.H.;
Yang, Yi;
Lin, Shunping;
Beatch, Gregory N.;
Ezrin, Alan M.;
Fedida, David

Publication type:

Article

Ventricular fibrillation, an uncontrolled arrhythmia seeking new targets.

Published in:

Drug Development Research, 2002, v. 55, n. 1, p. 45, doi. 10.1002/ddr.10038

By:

Beatch, Gregory N.;
Barrett, Terrance D.;
Plouvier, Bertrand;
Jung, Grace;
Wall, Richard A.;
Zolotoy, Alexander;
Walker, Michael J. A.

Publication type:

Article

Better antiarrhythmics? Development of antiarrhythmic drugs selective for ischaemia-dependent arrhythmias.

Published in:

Drug Development Research, 1997, v. 42, n. 3/4, p. 198, doi. 10.1002/(SICI)1098-2299(199711/12)42:3/4<198::AID-DDR11>3.0.CO;2-5

By:

Bain, Allen I.;
Barrett, Terrance D.;
Beatch, Gregory N.;
Fedida, David;
Hayes, Eric S.;
Plouvier, Bertrand;
Pugsley, Michael K.;
Walker, Michael J.A.;
Walker, Mariah L.;
Wall, Richard A.;
Yong, Sandro L.;
Zolotoy, Alexander

Publication type:

Article

Pharmacokinetics of XEN496, a Novel Pediatric Formulation of Ezogabine, Under Fed and Fasted Conditions: A Phase 1 Trial.

Published in:

Neurology & Therapy, 2022, v. 11, n. 2, p. 781, doi. 10.1007/s40120-022-00343-x

By:

Namdari, Rostam;
Luzon, Constanza;
Cadieux, Jay A.;
Leung, Jennifer;
Beatch, Gregory N.

Publication type:

Article

Kinetics of rate-dependent shortening of action potential duration in guinea-pig ventricle; effects of IK1 and IKr blockade.

Published in:

1999

By:

Williams, Beatrice A;
Dickenson, David R;
Beatch, Gregory N;
Williams, B A;
Dickenson, D R;
Beatch, G N

Publication type:

journal article

Pharmacokinetics of Novel Atrial-Selective Antiarrhythmic Agent Vernakalant Hydrochloride Injection (RSD1235): Influence of CYP2D6 Expression and Other Factors.

Published in:

Journal of Clinical Pharmacology, 2009, v. 49, n. 1, p. 17, doi. 10.1177/0091270008325148

By:

Mao, Zhongping L.;
Wheeler, Jeffery J.;
Clohs, Lilian;
Beatch, Gregory N.;
Keirns, James

Publication type:

Article

Efficacy and safety of vernakalant in patients with atrial flutter: a randomized, double-blind, placebo-controlled trial.

Published in:

EP: Europace, 2012, v. 14, n. 6, p. 804

By:

Camm, A. John;
Toft, Egon;
Torp-Pedersen, Christian;
Vijayaraman, Pugazhendhi;
Juul-Moller, Steen;
Ip, John;
Beatch, Gregory N.;
Dickinson, Garth;
Wyse, D. George

Publication type:

Article

Safety and efficacy of vernakalant for the conversion of atrial fibrillation to sinus rhythm; a phase 3b randomized controlled trial.

Published in:

2016

By:

Beatch, Gregory N.;
Mangal, Brian

Publication type:

journal article

Interim analysis of the long‐term efficacy and safety of azetukalner in an ongoing open‐label extension study following a phase 2b clinical trial (X‐TOLE) in adults with focal epilepsy.

Published in:

Epilepsia Open, 2025, v. 10, n. 2, p. 539, doi. 10.1002/epi4.70015

By:

French, Jacqueline A.;
Porter, Roger J.;
Perucca, Emilio;
Brodie, Martin J.;
Rogawski, Michael A.;
Harden, Cynthia;
Qian, Jenny;
Rosenblut, Constanza Luzon;
Kenney, Christopher;
Beatch, Gregory N.;
Abou‐Khalil, Bassel;
Aboumatar, Sami;
Armstrong, Robert;
Ayala, Ricardo;
Becerra, Juan Luis;
Bisulli, Francesca;
Biton, Victor;
Brandt, Christian;
Campos, Dulce;
Canafoglia, Laura

Publication type:

Article

The Mechanism of Atrial Antiarrhythmic Action of RSD1235.

Published in:

Journal of Cardiovascular Electrophysiology, 2005, v. 16, n. 11, p. 1227, doi. 10.1111/j.1540-8167.2005.50028.x

By:

FEDIDA, DAVID;
ORTH, PETER M.R.;
CHEN, JANET Y.C.;
LIN, SHUNPING;
PLOUVIER, BERTRAND;
JUNG, GRACE;
EZRIN, ALAN M.;
BEATCH, GREGORY N.

Publication type:

Article