Works matching AU Beal, M. Flint

Results: 216

Metabolomic profiling to develop blood biomarkers for Parkinson's disease.

Published in:

2008

By:

Bogdanov M;
Matson WR;
Wang L;
Matson T;
Saunders-Pullman R;
Bressman SS;
Flint Beal M;
Bogdanov, Mikhail;
Matson, Wayne R;
Wang, Lei;
Matson, Theodore;
Saunders-Pullman, Rachel;
Bressman, Susan S;
Flint Beal, M

Publication type:

journal article

Impaired mitochondrial function in psychiatric disorders.

Published in:

Nature Reviews Neuroscience, 2012, v. 13, n. 5, p. 293, doi. 10.1038/nrn3229

By:

Manji, Husseini;
Kato, Tadafumi;
Di Prospero, Nicholas A.;
Ness, Seth;
Beal, M. Flint;
Krams, Michael;
Chen, Guang

Publication type:

Article

Increased oxidative damage to DNA in an animal model of amyotrophic lateral sclerosis.

Published in:

Free Radical Research, 2005, v. 39, n. 4, p. 383, doi. 10.1080/10715760400027979

By:

Aguirre, Norberto;
Beal, M. Flint;
Matson, Wayne R.;
Bogdanov, Mikhail B.

Publication type:

Article

Urinary 8-hydroxy-2′-deoxyguanosine, a Metabolite of Oxidized DNA, is not Elevated in HIV Patients on Combination Antiretroviral Therapy.

Published in:

Free Radical Research, 2003, v. 37, n. 5, p. 499, doi. 10.1080/1071576031000076268

By:

Paul, Simon;
Bogdanov, Mikhail B.;
Matson, Wayne R.;
Metakis, Linda;
Jacobs, Jonathan;
Beal, M. Flint

Publication type:

Article

Coenzyme Q 10 as a Possible Treatment for Neurodegenerative Diseases.

Published in:

Free Radical Research, 2002, v. 36, n. 4, p. 455, doi. 10.1080/10715760290021315

By:

Beal, M. Flint

Publication type:

Article

Measuring the Effects of Therapy in Parkinson Disease.

Published in:

2004

By:

Shults, Clifford W.;
Haas, Richard;
Oakes, David;
Kieburtz, Karl;
Plumb, Sandra;
Shoulson, Ira;
Beal, M. Flint;
Juncos, Jorge;
Nutt, John

Publication type:

Letter

PGC-1α, Sirtuins and PARPs in Huntington's Disease and Other Neurodegenerative Conditions: NAD+ to Rule Them All.

Published in:

Neurochemical Research, 2019, v. 44, n. 10, p. 2423, doi. 10.1007/s11064-019-02809-1

By:

Lloret, Alejandro;
Beal, M. Flint

Publication type:

Article

Differential sparing of somatostatin-neuropeptide y and cholinergic neurons following striatal excitotoxin lesions.

Published in:

Synapse, 1989, v. 3, n. 1, p. 38, doi. 10.1002/syn.890030106

By:

Beal, M. Flint;
Kowall, Neil W.;
Swartz, Kenton J.;
Ferrante, Robert J.;
Martin, Joseph B.

Publication type:

Article

Somatostatin and neuropeptide Y immunoreactivity in parkinson's disease dementia with alzheimer's changes.

Published in:

Synapse, 1988, v. 2, n. 4, p. 463, doi. 10.1002/syn.890020415

By:

Flint Beal, M.;
Clevens, Ross A.;
Mazurek, Michael F.

Publication type:

Article

High‐dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy.

Published in:

Brain Pathology, 2020, v. 30, n. 5, p. 945, doi. 10.1111/bpa.12869

By:

Fourcade, Stéphane;
Goicoechea, Leire;
Parameswaran, Janani;
Schlüter, Agatha;
Launay, Nathalie;
Ruiz, Montserrat;
Seyer, Alexandre;
Colsch, Benoit;
Calingasan, Noel Ylagan;
Ferrer, Isidre;
Beal, M. Flint;
Sedel, Frédéric;
Pujol, Aurora

Publication type:

Article

Reply.

Published in:

Annals of Neurology, 2012, v. 72, n. 5, p. 823, doi. 10.1002/ana.23739

By:

Lin, Michael T.;
Cantuti-Castelvetri, Ippolita;
Lees, Andrew J.;
Beal, M. Flint;
Simon, David K.

Publication type:

Article

Somatic mitochondrial DNA mutations in early parkinson and incidental lewy body disease.

Published in:

Annals of Neurology, 2012, v. 71, n. 6, p. 850, doi. 10.1002/ana.23568

By:

Lin, Michael T.;
Cantuti-Castelvetri, Ippolita;
Zheng, Kangni;
Jackson, Katie E.;
Tan, Yong B.;
Arzberger, Thomas;
Lees, Andrew J.;
Betensky, Rebecca A.;
Beal, M. Flint;
Simon, David K.

Publication type:

Article

P1-069: Plaque formation is exacerbated in an animal model of the reduction in energy metabolism that accompanies Alzheimer's disease

Published in:

2008

By:

Gibson, Gary E.;
Karuppagounder, Saravanan S.;
Xu, Hui;
Shi, Qingli;
Chen, Lian-H;
Beal, Flint M.;
Gandy, Sam E.

Publication type:

Abstract

Common threads in neurodegenerative disorders of aging

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2006, v. 2, n. 4, p. 322, doi. 10.1016/j.jalz.2006.08.008

By:

Flint Beal, M.;
Bossy-Wetzel, Ella;
Finkbeiner, Steven;
Fiskum, Gary;
Giasson, Benoit;
Johnson, Carl;
Khachaturian, Zaven S.;
Lee, Virginia M.-Y.;
Nicholls, David;
Reddy, Hemachandra;
Reynolds, Ian;
Teplow, David B.;
Thal, Leon J.;
Trojanowski, John Q.;
Walsh, Dominic M.;
Wetzel, Ronald;
Wexler, Nancy S.;
Young, Anne B.;
Bain, Lisa

Publication type:

Article

Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection.

Published in:

Molecules, 2017, v. 22, n. 9, p. 1388, doi. 10.3390/molecules22091388

By:

Shurubor, Yevgeniya I.;
D'Aurelio, Marilena;
Clark-Matott, Joanne;
Isakova, Elena P.;
Deryabina, Yulia I.;
Beal, M. Flint;
Cooper, Arthur J. L.;
Krasnikov, Boris F.

Publication type:

Article

Aberrant regulation of the GSK‐3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 8, p. 1, doi. 10.15252/emmm.201708604

By:

Ranea‐Robles, Pablo;
Launay, Nathalie;
Ruiz, Montserrat;
Calingasan, Noel Ylagan;
Dumont, Magali;
Naudí, Alba;
Portero‐Otín, Manuel;
Pamplona, Reinald;
Ferrer, Isidre;
Beal, M. Flint;
Fourcade, Stéphane;
Pujol, Aurora

Publication type:

Article

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

Published in:

EMBO Molecular Medicine, 2010, v. 2, n. 9, p. 349, doi. 10.1002/emmm.201000084

By:

McConoughey, Stephen J.;
Basso, Manuela;
Niatsetskaya, Zoya V.;
Sleiman, Sama F.;
Smirnova, Natalia A.;
Langley, Brett C.;
Mahishi, Lata;
Cooper, Arthur J. L.;
Antonyak, Marc A.;
Cerione, Rick A.;
Li, Bo;
Starkov, Anatoly;
Chaturvedi, Rajnish Kumar;
Beal, M. Flint;
Coppola, Giovanni;
Geschwind, Daniel H.;
Ryu, Hoon;
Xia, Li;
Iismaa, Siiri E.;
Pallos, Judit

Publication type:

Article

Characterization of a Parkinson's disease rat model using an upgraded paraquat exposure paradigm.

Published in:

European Journal of Neuroscience, 2020, v. 52, n. 4, p. 3242, doi. 10.1111/ejn.14683

By:

Cristóvão, Ana Clara;
Campos, Filipa L.;
Je, Goun;
Esteves, Marta;
Guhathakurta, Subhrangshu;
Yang, Lichuan;
Beal, M. Flint;
Fonseca, Beatriz M.;
Salgado, Antonio J.;
Queiroz, João;
Sousa, Nuno;
Bernardino, Liliana;
Alves, Gilberto;
Yoon, Kyung‐Sik;
Kim, Yoon‐Seong

Publication type:

Article

Mitochondrial dysfunction and oxidative stress in induced pluripotent stem cell models of Parkinson's disease.

Published in:

European Journal of Neuroscience, 2019, v. 49, n. 4, p. 525, doi. 10.1111/ejn.14264

By:

Bose, Anindita;
Beal, M. Flint

Publication type:

Article

Minocycline enhances MPTP toxicity to dopaminergic neurons.

Published in:

Journal of Neuroscience Research, 2003, v. 74, n. 2, p. 278, doi. 10.1002/jnr.10709

By:

Lichuan Yang;
Shuei Sugama;
Jason W. Chirichigno;
Jason Gregorio;
Stefan Lorenzl;
Dong H. Shin;
Susan E. Browne;
Yoshinori Shimizu;
Tong H. Joh;
M. Flint Beal;
David S. Albers

Publication type:

Article

Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 9, p. 2467, doi. 10.1523/JNEUROSCI.5253-05.2006

By:

Kiaei, Mahmoud;
Petri, Susanne;
Kipiani, Khatuna;
Gardian, Gabrielle;
Dong-Kug Choi;
Junyu Chen;
Calingasan, Noel Y.;
Schafer, Peter;
Muller, George W.;
Stewart, Charles;
Hensley, Kenneth;
Beal, M. Flint

Publication type:

Article

Matrix Metalloproteinase-3: A Novel Signaling Proteinase from Apoptotic Neuronal Cells That Activates Microglia.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 14, p. 3701, doi. 10.1523/JNEUROSCI.4346-04.2005

By:

Yoon Seong Kim;
Sung Soo Kim;
Jeong Je Cho;
Dong Hoon Shin;
Dong Hee Choi;
Onyou Hwang;
Hong Sung Chun;
Beal, M. Flint;
Joh, Tong H.

Publication type:

Article

Mutant Superoxide Dismutase 1 Forms Aggregates in the Brain Mitochondrial Matrix of Amyotrophic Lateral Sclerosis Mice.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 10, p. 2463, doi. 10.1523/JNEUROSCI.4385-04.2005

By:

Vijayvergiya, Chetan;
Beal, M. Flint;
Buck, Jochen;
Manfredi, Giovanni

Publication type:

Article

Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 46, p. 10335, doi. 10.1523/JNEUROSCI.2599-04.2004

By:

Ferrante, Robert J.;
Ryu, Hoon;
Kubilus, James K.;
Lee, Junghee;
Smith, Karen;
D'Mello, Santosh;
Sugars, Katharine L.;
Rubinsztein, David C.;
Lu, Peiyuan;
Langley, Brett;
Browne, Susan;
Beal, M. Flint;
Hewett, Sandra;
Kristal, Bruce S.;
Stavrovskaya, Irina G.;
Ratan, Rajiv R.

Publication type:

Article

Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7945, doi. 10.1523/JNEUROSCI.2000-04.2004

By:

Kiaei, Mahmoud;
Bush, Ashley I.;
Morrison, Brett M.;
Morrison, John H.;
Cherny, Robert A.;
Volitakis, Irene;
Beal, M. Flint;
Gordon, Jon W.

Publication type:

Article

Mitochondrial α-Ketoglutarate Dehydrogenase Complex Generates Reactive Oxygen Species.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7779, doi. 10.1523/JNEUROSCI.1899-04.2004

By:

Starkov, Anatoly A.;
Fiskum, Gary;
Chinopoulos, Christos;
Lorenzo, Beverly J.;
Browne, Susan E.;
Patel, Mulchand S.;
Beal, M. Flint

Publication type:

Article

Prophylactic Creatine Administration Mediates Neuroprotection in Cerebral Ischemia in Mice.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 26, p. 5909, doi. 10.1523/JNEUROSCI.1278-04.2004

By:

Shan Zhu;
Mingwei Li;
Figueroa, Bryan E.;
Aijian Liu;
Stavrovskaya, Irina G.;
Pasinelli, Piera;
Beal, M. Flint;
Brown Jr., Robert H.;
Kristal, Bruce S.;
Ferrante, Robert J.;
Friedlander, Robert M.

Publication type:

Article

Mitochondria take center stage in aging and neurodegeneration.

Published in:

Annals of Neurology, 2005, v. 58, n. 4, p. 495

By:

M. Flint Beal

Publication type:

Article

Manganese porphyrin given at symptom onset markedly extends survival of ALS mice.

Published in:

Annals of Neurology, 2005, v. 58, n. 2, p. 258

By:

John P. Crow;
Noel Y. Calingasan;
Junyu Chen;
Julie Lynch Hill;
M. Flint Beal

Publication type:

Article

Poison and antidote: A novel model to study pathogenesis and therapy of LHON.

Published in:

Annals of Neurology, 2004, v. 56, n. 2, p. 171

By:

Giovanni Manfredi;
M. Flint Beal

Publication type:

Article

Bioenergetic approaches for neuroprotection in Parkinson's disease.

Published in:

Annals of Neurology, 2003, v. 53, n. s3, p. S39

By:

M. Flint Beal

Publication type:

Article

Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease.

Published in:

2001

By:

Andreassen, Ole A.;
Ferrante, Robert J.;
Huang, Hsueh-Meei;
Dedeoglu, Alpaslan;
Park, Larry;
Ferrante, Kimberly L.;
Kwon, Jennifer;
Borchelt, David R.;
Ross, Christopher A.;
Gibson, Gary E.;
Beal, M. Flint;
Andreassen, O A;
Ferrante, R J;
Huang, H M;
Dedeoglu, A;
Park, L;
Ferrante, K L;
Kwon, J;
Borchelt, D R;
Ross, C A

Publication type:

journal article

Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders.

Published in:

Annals of Neurology, 2001, v. 49, n. 5, p. 561, doi. 10.1002/ana.1028

By:

Tarnopolsky, Mark A.;
Beal, M. Flint

Publication type:

Article

Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 2000, v. 47, n. 4, p. 447, doi. 10.1002/1531-8249(200004)47:4<447::AID-ANA7>3.0.CO;2-R

By:

Andreassen, Ole A.;
Ferrante, Robert J.;
Klivenyi, Peter;
Klein, Autumn M.;
Shinobu, Leslie A.;
Epstein, Charles J.;
Flint Beal, M.

Publication type:

Article

Huntington aggregates may not predict neuronal death in Huntington's disease.

Published in:

1999

By:

Kuemmerle, Stefan;
Gutekunst, Claire-Anne;
Klein, Autumn M.;
Li, Xiao-Jiang;
Li, Shi-Hua;
Beal, M. Flint;
Hersch, Steven M.;
Ferrante, Robert J.;
Kuemmerle, S;
Gutekunst, C A;
Klein, A M;
Li, X J;
Li, S H;
Beal, M F;
Hersch, S M;
Ferrante, R J

Publication type:

journal article

Reply.

Published in:

Annals of Neurology, 1999, v. 45, n. 3, p. 414, doi. 10.1002/1531-8249(199903)45:3<414::AID-ANA25>3.0.CO;2-1

By:

Beal, M. Flint

Publication type:

Article

Foreword.

Published in:

1998

By:

Warren, C. Olanow;
Jenner, Peter;
Beal, M. Flint

Publication type:

Editorial

Excitotoxicity and nitric oxide in parkinson's disease pathogenesis.

Published in:

Annals of Neurology, 1998, v. 44, p. S110, doi. 10.1002/ana.410440716

By:

M. Flint Beal

Publication type:

Article

Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 1997, v. 42, n. 4, p. 644, doi. 10.1002/ana.410420416

By:

Beal, M. Flint;
Ferrante, Robert J.;
Browne, Susan E.;
Matthews, Russell T.;
Kowall, Neil W.;
Brown, Robert H.

Publication type:

Article

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

Published in:

1997

By:

Ferrante, Robert J.;
Shinobu, Leslie A.;
Schulz, Jörg B.;
Matthews, Russell T.;
Thomas, Craig E.;
Kowall, Neil W.;
Gurney, Mark E.;
Beal, M. Flint;
Ferrante, R J;
Shinobu, L A;
Schulz, J B;
Matthews, R T;
Thomas, C E;
Kowall, N W;
Gurney, M E;
Beal, M F

Publication type:

journal article

Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects.

Published in:

Annals of Neurology, 1997, v. 42, n. 2, p. 261, doi. 10.1002/ana.410420221

By:

Shults, Clifford W.;
Haas, Richard H.;
Passov, David;
Beal, M. Flint

Publication type:

Article

Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia.

Published in:

Annals of Neurology, 1997, v. 41, n. 5, p. 646, doi. 10.1002/ana.410410514

By:

Browne, Susan E.;
Bowling, Allen C.;
Macgarvey, Usha;
Baik, M. Jay;
Berger, Stephanie C.;
Muquit, Miratul M. K.;
Bird, Edward D.;
Beal, M. Flint

Publication type:

Article

Cortical peptide changes in Huntington's disease may be independent of striatal degeneration.

Published in:

Annals of Neurology, 1997, v. 41, n. 4, p. 540, doi. 10.1002/ana.410410418

By:

Mazurek, Michael F.;
Garside, Sarah;
Beal, M. Flint

Publication type:

Article

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

Published in:

Annals of Neurology, 1997, v. 41, n. 2, p. 160, doi. 10.1002/ana.410410206

By:

Koroshetz, Walter J.;
Jenkins, Bruce G.;
Rosen, Bruce R.;
Beal, M. Flint

Publication type:

Article

Reply.

Published in:

Annals of Neurology, 1996, v. 39, n. 6, p. 824, doi. 10.1002/ana.410390624

By:

Beal, M. Flint

Publication type:

Article

Aging, energy, and oxidative stress in neurodegenerative diseases.

Published in:

Annals of Neurology, 1995, v. 38, n. 3, p. 357, doi. 10.1002/ana.410380304

By:

Beal, M. Flint

Publication type:

Article

Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate.

Published in:

Annals of Neurology, 1994, v. 36, n. 6, p. 882, doi. 10.1002/ana.410360613

By:

Beal, M. Flint;
Henshaw, D. Ross;
Jenkins, Bruce G.;
Rosen, Bruce R.;
Schulz, Jourg B.

Publication type:

Article

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease.

Published in:

Annals of Neurology, 1994, v. 36, n. 5, p. 747, doi. 10.1002/ana.410360510

By:

Mecocci, Patrizia;
MacGarvey, Usha;
Beal, M. Flint

Publication type:

Article

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

Published in:

Annals of Neurology, 1993, v. 34, n. 4, p. 609, doi. 10.1002/ana.410340416

By:

Mecocci, Patrizia;
MacGarvey, Usha;
Kaufman, Allan E.;
Koontz, Deborah;
Shoffner, John M.;
Wallace, Douglas C.;
Beal, M. Flint

Publication type:

Article

The cortical lesion of Huntington's disease: Further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl- D-aspartate lesions of rat cortex.

Published in:

Annals of Neurology, 1992, v. 32, n. 4, p. 526, doi. 10.1002/ana.410320408

By:

Storey, Elsdon;
Kowall, Neil W.;
Finn, Stephen F.;
Mazurek, Michael F.;
Beal, M. Flint

Publication type:

Article