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A fully human monoclonal antibody possesses antibody‐dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a conserved epitope at the HA1 protomer interface.
Published in:
Journal of Medical Virology, 2023, v. 95, n. 7, p. 1, doi. 10.1002/jmv.28901
By:
- Gao, Rongyuan;
- Wang, Zhao;
- Uprety, Tirth;
- Sreenivasan, Chithra C.;
- Sheng, Zizhang;
- Hause, Ben M.;
- Brunick, Colin;
- Wu, Hua;
- Luke, Thomas;
- Bausch, Christoph L.;
- Sullivan, Eddie J.;
- Hoppe, Adam D.;
- Huber, Victor C.;
- Wang, Dan;
- Li, Feng
Publication type:
Article
No evidence for enhanced disease with human polyclonal SARS-CoV-2 antibody in the ferret model.
Published in:
PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0290909
By:
- Reed, Douglas S.;
- McElroy, Anita K.;
- Barbeau, Dominique J.;
- McMillen, Cynthia M.;
- Tilston-Lunel, Natasha L.;
- Nambulli, Shamkumar;
- Cottle, Emily;
- Gilliland, Theron C.;
- Rannulu, Hasala;
- Lundy, Jeneveve;
- Olsen, Emily L.;
- O'Malley, Katherine J.;
- Xia, Mengying;
- Hartman, Amy L.;
- Luke, Thomas C.;
- Egland, Kristi;
- Bausch, Christoph;
- Wu, Hua;
- Sullivan, Eddie J.;
- Klimstra, William B.
Publication type:
Article
Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Plague.
Published in:
Antibodies (2073-4468), 2023, v. 12, n. 2, p. 33, doi. 10.3390/antib12020033
By:
- Biryukov, Sergei S.;
- Wu, Hua;
- Dankmeyer, Jennifer L.;
- Rill, Nathaniel O.;
- Klimko, Christopher P.;
- Egland, Kristi A.;
- Shoe, Jennifer L.;
- Hunter, Melissa;
- Fetterer, David P.;
- Qiu, Ju;
- Davies, Michael L.;
- Bausch, Christoph L.;
- Sullivan, Eddie J.;
- Luke, Thomas;
- Cote, Christopher K.
Publication type:
Article
Phase 2 Safety and Antiviral Activity of SAB-185, a Novel Polyclonal Antibody Therapy for Nonhospitalized Adults With COVID-19.
Published in:
Journal of Infectious Diseases, 2023, v. 228, n. 2, p. 133, doi. 10.1093/infdis/jiad013
By:
- Taiwo, Babafemi O;
- Chew, Kara W;
- Moser, Carlee;
- Wohl, David Alain;
- Daar, Eric S;
- Li, Jonathan Z;
- Greninger, Alexander L;
- Bausch, Christoph;
- Luke, Thomas;
- Hoover, Keila;
- Neytman, Gene;
- Giganti, Mark J;
- Olefsky, Maxine;
- Javan, Arzhang Cyrus;
- Fletcher, Courtney V;
- Eron, Joseph J;
- Currier, Judith S;
- Hughes, Michael D;
- Smith, Davey M;
- Team, for the ACTIV-2/A5401 Study
Publication type:
Article
Increased Antibody Avidity and Cross-Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Variants by Hyperimmunized Transchromosomic Bovine-Derived Human Immunoglobulins for Treatment of Coronavirus Disease 2019.
Published in:
Journal of Infectious Diseases, 2022, v. 226, n. 4, p. 655, doi. 10.1093/infdis/jiac031
By:
- Tang, Juanjie;
- Grubbs, Gabrielle;
- Lee, Youri;
- Wu, Hua;
- Luke, Thomas C;
- Egland, Kristi A;
- Bausch, Christoph L;
- Sullivan, Eddie J;
- Khurana, Surender
Publication type:
Article
Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models.
Published in:
Frontiers in Microbiology, 2020, v. 11, p. 1, doi. 10.3389/fmicb.2020.00832
By:
- Perley, Casey C.;
- Brocato, Rebecca L.;
- Wu, Hua;
- Bausch, Christoph;
- Karmali, Priya P.;
- Vega, Jerel B.;
- Cohen, Melanie V.;
- Somerville, Brandon;
- Kwilas, Steven A.;
- Principe, Lucia M.;
- Shamblin, Joshua;
- Chivukula, Padmanabh;
- Sullivan, Eddie;
- Hooper, Jay W.
Publication type:
Article

Found: 6

A fully human monoclonal antibody possesses antibody‐dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a conserved epitope at the HA1 protomer interface.

No evidence for enhanced disease with human polyclonal SARS-CoV-2 antibody in the ferret model.

Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Plague.

Phase 2 Safety and Antiviral Activity of SAB-185, a Novel Polyclonal Antibody Therapy for Nonhospitalized Adults With COVID-19.

Increased Antibody Avidity and Cross-Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Variants by Hyperimmunized Transchromosomic Bovine-Derived Human Immunoglobulins for Treatment of Coronavirus Disease 2019.

Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models.