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Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.
Published in:
2019
By:
- Allen, Scott P;
- Hall, Benjamin;
- Castelli, Lydia M;
- Francis, Laura;
- Woof, Ryan;
- Siskos, Alexandros P;
- Kouloura, Eirini;
- Gray, Elizabeth;
- Thompson, Alexander G;
- Talbot, Kevin;
- Higginbottom, Adrian;
- Myszczynska, Monika;
- Allen, Chloe F;
- Stopford, Matthew J;
- Hemingway, Jordan;
- Bauer, Claudia S;
- Webster, Christopher P;
- Vos, Kurt J De;
- Turner, Martin R;
- Keun, Hector C
Publication type:
journal article
Proteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.21143
By:
- Kadurin, Ivan;
- Ferron, Laurent;
- Rothwell, Simon W.;
- Meyer, James O.;
- Douglas, Leon R.;
- Bauer, Claudia S.;
- Lana, Beatrice;
- Margas, Wojciech;
- Alexopoulos, Orpheas;
- Nieto-Rostro, Manuela;
- Pratt, Wendy S.;
- Dolphin, Annette C.
Publication type:
Article
Differential expression and regulation of K[sup+] channels in the maize coleoptile: molecular and biophysical analysis of cells isolated from cortex and vasculature.
Published in:
Plant Journal, 2000, v. 24, n. 2, p. 139, doi. 10.1046/j.1365-313X.2000.00844.x
By:
- Bauer, Claudia S.;
- Hoth, Stefan;
- Haga, Ken;
- Philippar, Katrin;
- Aoki, Naohiro;
- Hedrich, Rainer
Publication type:
Article
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation.
Published in:
Frontiers in Cellular Neuroscience, 2022, v. 16, p. 01, doi. 10.3389/fncel.2022.1061559
By:
- Bauer, Claudia S.;
- Webster, Christopher P.;
- Shaw, Allan C.;
- Kok, Jannigje R.;
- Castelli, Lydia M.;
- Ya-Hui Lin;
- Smith, Emma F.;
- Illanes-Álvarez, Francisco;
- Higginbottom, Adrian;
- Shaw, Pamela J.;
- Azzouz, Mimoun;
- Ferraiuolo, Laura;
- Hautbergue, Guillaume M.;
- Grierson, Andrew J.;
- De Vos, Kurt J.
Publication type:
Article
The Increased Trafficking of the Calcium Channel Subunit α2δ-1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the α2δ Ligand Pregabalin.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 13, p. 4076, doi. 10.1523/JNEUROSCI.0356-09.2009
By:
- Bauer, Claudia S.;
- Nieto-Rostro, Manuela;
- Rahman, Wahida;
- Tran-Van-Minh, Alexandra;
- Ferron, Laurent;
- Douglas, Leon;
- Kadurin, Ivan;
- Ranjan, Yorain Sri;
- Fernandez-Alacid, Laura;
- Millar, Neil S.;
- Dickenson, Anthony H.;
- Lujan, Rafael;
- Dolphin, Annette C.
Publication type:
Article
Differential Regulation of Endogenous N- and P/Q-Type Ca2+ Channel Inactivation by Ca2+/Calmodulin Impacts on Their Ability to Support Exocytosis in Chromaffin Cells.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 19, p. 5236, doi. 10.1523/JNEUROSCI.3545-06.2007
By:
- Wykes, Robert C. E.;
- Bauer, Claudia S.;
- Khan, Saeed U.;
- Weiss, Jamie L.;
- Seward, Elizabeth P.
Publication type:
Article
Potentiation of Exocytosis by Phospholipase C-Coupled G-Protein-Coupled Receptors Requires the Priming Protein Munc13-1.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 1, p. 212, doi. 10.1523/JNEUROSCI.4201-06.2007
By:
- Bauer, Claudia S.;
- Woolley, Robert J.;
- Teschemacher, Anja G.;
- Seward, Elizabeth P.
Publication type:
Article
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.
Published in:
EMBO Journal, 2016, v. 35, n. 15, p. 1656, doi. 10.15252/embj.201694401
By:
- Webster, Christopher P;
- Smith, Emma F;
- Bauer, Claudia S;
- Moller, Annekathrin;
- Hautbergue, Guillaume M;
- Ferraiuolo, Laura;
- Myszczynska, Monika A;
- Higginbottom, Adrian;
- Walsh, Matthew J;
- Whitworth, Alexander J;
- Kaspar, Brian K;
- Meyer, Kathrin;
- Shaw, Pamela J;
- Grierson, Andrew J;
- De Vos, Kurt J
Publication type:
Article
Different Xanthines Cause Membrane Potential Oscillations in a Unicellular Green Alga Pointing to a Ryanodine/cADPR Receptor Ca2+ Channel.
Published in:
Plant & Cell Physiology, 1999, v. 40, n. 4, p. 453, doi. 10.1093/oxfordjournals.pcp.a029563
By:
- Bauer, Claudia S.;
- Simonis, Wilhelm;
- Schönknecht, Gerald
Publication type:
Article
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits.
Published in:
Nature Communications, 2017, v. 8, n. 7, p. 16063, doi. 10.1038/ncomms16063
By:
- Hautbergue, Guillaume M.;
- Castelli, Lydia M.;
- Ferraiuolo, Laura;
- Sanchez-Martinez, Alvaro;
- Cooper-Knock, Johnathan;
- Higginbottom, Adrian;
- Lin, Ya-Hui;
- Bauer, Claudia S.;
- Dodd, Jennifer E.;
- Myszczynska, Monika A.;
- Alam, Sarah M.;
- Garneret, Pierre;
- Chandran, Jayanth S.;
- Karyka, Evangelia;
- Stopford, Matthew J.;
- Smith, Emma F.;
- Kirby, Janine;
- Meyer, Kathrin;
- Kaspar, Brian K.;
- Isaacs, Adrian M.
Publication type:
Article
Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P2.
Published in:
Nature, 2002, v. 419, n. 6910, p. 947, doi. 10.1038/nature01118
By:
- Wu, Li;
- Bauer, Claudia S.;
- Zhen, Xiao-guang;
- Xie, Cheng;
- Yang, Jian
Publication type:
Article
Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 23, p. 4668, doi. 10.1093/hmg/ddx348
By:
- Moller, Annekathrin;
- Bauer, Claudia S.;
- Cohen, Rebecca N.;
- Webster, Christopher P.;
- De Vos, Kurt J.
Publication type:
Article
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.
Published in:
Acta Neuropathologica, 2022, v. 144, n. 3, p. 437, doi. 10.1007/s00401-022-02470-z
By:
- Bauer, Claudia S.;
- Cohen, Rebecca N.;
- Sironi, Francesca;
- Livesey, Matthew R.;
- Gillingwater, Thomas H.;
- Highley, J. Robin;
- Fillingham, Daniel J.;
- Coldicott, Ian;
- Smith, Emma F.;
- Gibson, Yolanda B.;
- Webster, Christopher P.;
- Grierson, Andrew J.;
- Bendotti, Caterina;
- De Vos, Kurt J.
Publication type:
Article
A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins.
Published in:
Science Translational Medicine, 2023, v. 15, n. 685, p. 1, doi. 10.1126/scitranslmed.abo3823
By:
- Castelli, Lydia M.;
- Lin, Ya-Hui;
- Sanchez-Martinez, Alvaro;
- Gül, Aytaç;
- Mohd Imran, Kamallia;
- Higginbottom, Adrian;
- Upadhyay, Santosh Kumar;
- Márkus, Nóra M.;
- Rua Martins, Raquel;
- Cooper-Knock, Johnathan;
- Montmasson, Claire;
- Cohen, Rebecca;
- Walton, Amy;
- Bauer, Claudia S.;
- De Vos, Kurt J.;
- Mead, Richard J.;
- Azzouz, Mimoun;
- Dominguez, Cyril;
- Ferraiuolo, Laura;
- Shaw, Pamela J.
Publication type:
Article
α2δ-1 Gene Deletion Affects Somatosensory Neuron Function and Delays Mechanical Hypersensitivity in Response to Peripheral Nerve Damage.
Published in:
Journal of Neuroscience, 2013, v. 33, n. 42, p. 16412, doi. 10.1523/JNEUROSCI.1026-13.2013
By:
- Patel, Ryan;
- Bauer, Claudia S.;
- Nieto-Rostro, Manuela;
- Margas, Wojciech;
- Ferron, Laurent;
- Chaggar, Kanchan;
- Crews, Kasumi;
- Ramirez, Juan D.;
- Bennett, David L. H.;
- Schwartz, Arnold;
- Dickenson, Anthony H.;
- Dolphin, Annette C.
Publication type:
Article

Found: 15

Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.

Proteolytic maturation of α<sub>2</sub>δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.

Differential expression and regulation of K[sup+] channels in the maize coleoptile: molecular and biophysical analysis of cells isolated from cortex and vasculature.

Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation.

The Increased Trafficking of the Calcium Channel Subunit α<sub>2</sub>δ-1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the α<sub>2</sub>δ Ligand Pregabalin.

Differential Regulation of Endogenous N- and P/Q-Type Ca<sup>2+</sup> Channel Inactivation by Ca<sup>2+</sup>/Calmodulin Impacts on Their Ability to Support Exocytosis in Chromaffin Cells.

Potentiation of Exocytosis by Phospholipase C-Coupled G-Protein-Coupled Receptors Requires the Priming Protein Munc13-1.

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.

Different Xanthines Cause Membrane Potential Oscillations in a Unicellular Green Alga Pointing to a Ryanodine/cADPR Receptor Ca2+ Channel.

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits.

Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P<sub>2</sub>.

Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels.

An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.

A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins.

α<sub>2</sub>δ-1 Gene Deletion Affects Somatosensory Neuron Function and Delays Mechanical Hypersensitivity in Response to Peripheral Nerve Damage.