Works by Barzilai, Nir

Results: 189

Disease drivers of aging.

Published in:

Annals of the New York Academy of Sciences, 2016, v. 1386, n. 1, p. 45, doi. 10.1111/nyas.13299

By:

Hodes, Richard J.;
Sierra, Felipe;
Austad, Steven N.;
Epel, Elissa;
Neigh, Gretchen N.;
Erlandson, Kristine M.;
Schafer, Marissa J.;
LeBrasseur, Nathan K.;
Wiley, Christopher;
Campisi, Judith;
Sehl, Mary E.;
Scalia, Rosario;
Eguchi, Satoru;
Kasinath, Balakuntalam S.;
Halter, Jeffrey B.;
Cohen, Harvey Jay;
Demark‐Wahnefried, Wendy;
Ahles, Tim A.;
Barzilai, Nir;
Hurria, Arti

Publication type:

Article

Lipoprotein Genotype and Conserved Pathway for Exceptional Longevity in Humans.

Published in:

PLoS Biology, 2006, v. 4, n. 4, p. e113, doi. 10.1371/journal.pbio.0040113

By:

Atzmon, Gil;
Rincon, Marielisa;
Schechter, Clyde B.;
Shuldiner, Alan R.;
Lipton, Richard B.;
Bergman, Aviv;
Barzilai, Nir

Publication type:

Article

Role of APOE Genotype in Gait Decline and Disability in Aging.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 11, p. 1395, doi. 10.1093/gerona/glt115

By:

Verghese, Joe;
Holtzer, Roee;
Wang, Cuiling;
Katz, Mindy J.;
Barzilai, Nir;
Lipton, Richard B.

Publication type:

Article

Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 12, p. 1307, doi. 10.1093/gerona/glr235

By:

Crandall, Jill P.;
Oram, Valerie;
Trandafirescu, Georgeta;
Reid, Migdalia;
Kishore, Preeti;
Hawkins, Meredith;
Cohen, Hillel W.;
Barzilai, Nir

Publication type:

Article

Fatty Acid-Induced Production of Plasminogen Activator Inhibitor-1 by Adipose Macrophages Is Greater in Middle-Aged Versus Younger Adult Participants.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 12, p. 1321, doi. 10.1093/gerona/gls200

By:

Esterson, Yonah B.;
Kishore, Preeti;
Koppaka, Sudha;
Li, Weijie;
Zhang, Kehao;
Tonelli, Julia;
Lee, Do-Eun;
Kehlenbrink, Sylvia;
Lawrence, Stephanie;
Crandall, Jill;
Barzilai, Nir;
Hawkins, Meredith

Publication type:

Article

Insulin Resistance and Aging: A Cause or a Protective Response?

Published in:

2012

By:

Barzilai, Nir;
Ferrucci, Luigi

Publication type:

Editorial

Distinguishing Between Longevity and Buffered-Deleterious Genotypes for Exceptional Human Longevity: The Case of the MTP Gene.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 11, p. 1153, doi. 10.1093/gerona/gls103

By:

Huffman, Derek M.;
Deelen, Joris;
Ye, Kenny;
Bergman, Aviv;
Slagboom, Eline P.;
Barzilai, Nir;
Atzmon, Gil

Publication type:

Article

Aging per se increases the susceptibility to free fatty acid-induced insulin resistance.

Published in:

2010

By:

Einstein FH;
Huffman DM;
Fishman S;
Jerschow E;
Heo HJ;
Atzmon G;
Schechter C;
Barzilai N;
Muzumdar RH;
Einstein, Francine H;
Huffman, Derek M;
Fishman, Sigal;
Jerschow, Elina;
Heo, Hye J;
Atzmon, Gil;
Schechter, Clyde;
Barzilai, Nir;
Muzumdar, Radhika H

Publication type:

journal article

Aging per se Increases the Susceptibility to Free Fatty Acid–Induced Insulin Resistance.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2010, v. 65A, n. 8, p. 800, doi. 10.1093/gerona/glq078

By:

Einstein, Francine H.;
Huffman, Derek M.;
Fishman, Sigal;
Jerschow, Elina;
Heo, Hye J.;
Atzmon, Gil;
Schechter, Clyde;
Barzilai, Nir;
Muzumdar, Radhika H.

Publication type:

Article

Biological Approaches to Mechanistically Understand the Healthy Life Span Extension Achieved by Calorie Restriction and Modulation of Hormones.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2009, v. 64A, n. 2, p. 187, doi. 10.1093/gerona/gln061

By:

Barzilai, Nir;
Bartke, Andrzej

Publication type:

Article

Adiponectin Levels and Genotype: A Potential Regulator of Life Span in Humans.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2008, v. 63, n. 5, p. 447, doi. 10.1093/gerona/63.5.447

By:

Atzmon, Gil;
Pollin, Toni I.;
Crandall, Jill;
Tanner, Keith;
Schechter, Clyde B.;
Scherer, Philipp E.;
Rincon, Marielisa;
Siegel, Glenn;
Katz, Micol;
Lipton, Richard B.;
Shuldiner, Alan R.;
Barzilai, Nir

Publication type:

Article

The Biological Sciences Section Program at the 57th Annual Meeting of The Gerontological Society of America.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2005, v. 60, n. 11, p. 1359, doi. 10.1093/gerona/60.11.1359

By:

Jazwinski, S. Michal;
Warner, Huber R.;
Helfand, Stephen;
Driscoll, Monica;
Welsh, David A.;
Faulkner, John;
Barzilai, Nir;
Breitenbach, Michael;
McCarter, Roger;
Brow, W. Ted;
Greco, Nicholas;
Mountz, John;
Olshansky, S. Jay

Publication type:

Article

Longevity genes: from primitive organisms to humans.

Published in:

2003

By:

Butler, Robert N.;
Austad, Steven N.;
Barzilai, Nir;
Braun, Andreas;
Helfand, Stephen;
Larsen, Pamela L.;
McCormick, Anna M.;
Perls, Thomas T.;
Shuldiner, Alan R.;
Sprott, Richard L.;
Warner, Huber R.

Publication type:

research

Discovering the secrets of successful longevity.

Published in:

2003

By:

Barzilai, Nir

Publication type:

commentary

Plasma HDL levels highly correlate with cognitive function in exceptional longevity.

Published in:

2002

By:

Atzmon G;
Gabriely I;
Greiner W;
Davidson D;
Schechter C;
Barzilai N;
Atzmon, Gil;
Gabriely, Ilan;
Greiner, William;
Davidson, Deborah;
Schechter, Clyde;
Barzilai, Nir

Publication type:

journal article

Plasma HDL Levels Highly Correlate With Cognitive Function in Exceptional Longevity.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2002, v. 57, n. 11, p. M712, doi. 10.1093/gerona/57.11.M712

By:

Atzmon, Gil;
Gabriely, Ilan;
Davidson, Deborah;
Schechter, Clyde;
Barzilai, Nir

Publication type:

Article

Aging is associated with resistance to effects of leptin on fat distribution and insulin action.

Published in:

2002

By:

Ma, Xiao Hui;
Muzumdar, Radhika;
Yang, Xiao Man;
Gabriely, Ilan;
Berger, Rachel;
Barzilai, Nir

Publication type:

journal article

Aging Is Associated With Resistance to Effects of Leptin on Fat Distribution and Insulin Action.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2002, v. 57, n. 6, p. B225

By:

Xiao Hui Ma;
Muzumdar, Radhika;
Xiao Man Yang;
Gabriely, Ilan;
Berger, Rachel;
Barzilai, Nir

Publication type:

Article

Searching for human longevity genes: the future history of gerontology in the post-genomic era.

Published in:

2001

By:

Barzilai, Nir;
Shuldiner, Alan R.;
Barzilai, N;
Shuldiner, A R

Publication type:

journal article

Author's Repsonse to Commentary on `Revisiting the Role of Fat Mass in the Life Extension Induced...

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 1999, v. 54, n. 3, p. B98, doi. 10.1093/gerona/54.3.B98

By:

Barzilai, Nir

Publication type:

Article

The Effect of Age-Dependent Increase in Fat Mass on Peripheral Insulin Action is Saturable.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 1998, v. 53A, n. 2, p. B141, doi. 10.1093/gerona/53A.2.B141

By:

Barzilai, Nir;
Banerjee, Swati

Publication type:

Article

Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-94094-y

By:

Ali, Amanat;
Zhang, Zhengdong D.;
Gao, Tina;
Aleksic, Sandra;
Gavathiotis, Evripidis;
Barzilai, Nir;
Milman, Sofiya

Publication type:

Article

Depletion of loss-of-function germline mutations in centenarians reveals longevity genes.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52967-2

By:

Ying, Kejun;
Castro, José P.;
Shindyapina, Anastasia V.;
Tyshkovskiy, Alexander;
Moqri, Mahdi;
Goeminne, Ludger J. E.;
Milman, Sofiya;
Zhang, Zhengdong D.;
Barzilai, Nir;
Gladyshev, Vadim N.

Publication type:

Article

Association of exceptional parental longevity and physical function in aging.

Published in:

Age (0161-9152), 2014, v. 36, n. 4, p. 1, doi. 10.1007/s11357-014-9677-5

By:

Ayers, Emmeline;
Barzilai, Nir;
Crandall, Jill;
Milman, Sofiya;
Verghese, Joe

Publication type:

Article

Plasma proteomic characterization of motoric cognitive risk and mild cognitive impairment.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 2, p. 1, doi. 10.1002/alz.14429

By:

Gomez, Gabriela T.;
Sathyan, Sanish;
Chen, Jingsha;
Fornage, Myriam;
Schlosser, Pascal;
Peng, Zhongsheng;
Cordon, Jenifer;
Palta, Priya;
Sullivan, Kevin J.;
Tin, Adrienne;
Windham, B. Gwen;
Gottesman, Rebecca F.;
Barzilai, Nir;
Milman, Sofiya;
Verghese, Joe;
Coresh, Josef;
Walker, Keenan A.

Publication type:

Article

Genetic variants associated with age‐related episodic memory decline implicate distinct memory pathologies.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 1, p. 1, doi. 10.1002/alz.14379

By:

Ali, Amanat;
Milman, Sofiya;
Weiss, Erica F.;
Gao, Tina;
Napolioni, Valerio;
Barzilai, Nir;
Zhang, Zhengdong D.;
Lin, Jhih‐Rong

Publication type:

Article

Biological Aging and the Motoric Cognitive Risk Syndrome.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.089384

By:

Sathyan, Sanish;
Oh, Hamilton Se‐Hwee;
Emmeline, Ayers;
Rutledge, Jarod;
Adhikari, Dristi;
Gao, Tina;
Milman, Sofiya;
Wyss‐Coray, Tony;
Barzilai, Nir;
Verghese, Joe

Publication type:

Article

Structural Brain Correlates of Physical Activity in Offspring of Parents with and without Exceptional Longevity.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076528

By:

Delpratt, Natalie A;
Barzilai, Nir;
Milman, Sofiya;
Verghese, Joe;
Blumen, Helena M

Publication type:

Article

Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

Published in:

2019

By:

Rivas, Manuel A.;
Avila, Brandon E.;
Koskela, Jukka;
Huang, Hailiang;
Stevens, Christine;
Pirinen, Matti;
Haritunians, Talin;
Neale, Benjamin M.;
Kurki, Mitja;
Ganna, Andrea;
Graham, Daniel;
Glaser, Benjamin;
Peter, Inga;
Atzmon, Gil;
Barzilai, Nir;
Levine, Adam P.;
Schiff, Elena;
Pontikos, Nikolas;
Weisburd, Ben;
Lek, Monkol

Publication type:

Correction Notice

Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults.

Published in:

Cells (2073-4409), 2020, v. 9, n. 6, p. 1368, doi. 10.3390/cells9061368

By:

Zhang, William B.;
Aleksic, Sandra;
Gao, Tina;
Weiss, Erica F.;
Demetriou, Eleni;
Verghese, Joe;
Holtzer, Roee;
Barzilai, Nir;
Milman, Sofiya

Publication type:

Article

The Rationale for Delaying Aging and the Prevention of Age-Related Diseases.

Published in:

2012

By:

Barzilai, Nir;
Rennert, Gad

Publication type:

Editorial

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23556-4

By:

Goodrich, Julia K.;
Singer-Berk, Moriel;
Son, Rachel;
Sveden, Abigail;
Wood, Jordan;
England, Eleina;
Cole, Joanne B.;
Weisburd, Ben;
Watts, Nick;
Caulkins, Lizz;
Dornbos, Peter;
Koesterer, Ryan;
Zappala, Zachary;
Zhang, Haichen;
Maloney, Kristin A.;
Dahl, Andy;
Aguilar-Salinas, Carlos A.;
Atzmon, Gil;
Barajas-Olmos, Francisco;
Barzilai, Nir

Publication type:

Article

Clinical Use of Metformin in the United States.

Published in:

Diabetes Spectrum, 1995, v. 8, n. 4, p. 194

By:

Barzilai, Nir

Publication type:

Article

Surgical removal of visceral adipose tissue: Effects on insulin action.

Published in:

Current Diabetes Reports, 2003, v. 3, n. 3, p. 201, doi. 10.1007/s11892-003-0064-3

By:

Gabriely, Ilan;
Barzilai, Nir

Publication type:

Article

Metformin for Treatment of Acute COVID-19: Systematic Review of Clinical Trial Data Against SARS-CoV-2.

Published in:

Diabetes Care, 2023, v. 46, n. 7, p. 1432, doi. 10.2337/dc22-2539

By:

Erickson, Spencer M.;
Fenno, Sarah L.;
Barzilai, Nir;
Kuchel, George;
Bartley, Jenna M.;
Justice, Jamie Nicole;
Buse, John B.;
Bramante, Carolyn T.

Publication type:

Article

A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci.

Published in:

PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002559

By:

Kenny, Eimear E.;
Pe'er, Itsik;
Karban, Amir;
Ozelius, Laurie;
Mitchell, Adele A.;
Sok Meng Ng;
Erazo, Monica;
Ostrer, Harry;
Abraham, Clara;
Abreu, Maria T.;
Atzmon, Gil;
Barzilai, Nir;
Brant, Steven R.;
Bressman, Susan;
Burns, Edward R.;
Chowers, Yehuda;
Clark, Lorraine N.;
Darvasi, Ariel;
Doheny, Dana;
Duerr, Richard H.

Publication type:

Article

Genetic Determinants of Human Health Span and Life Span: Progress and New Opportunities.

Published in:

PLoS Genetics, 2007, v. 3, n. 7, p. e125, doi. 10.1371/journal.pgen.0030125

By:

Martin, George M.;
Bergman, Aviv;
Barzilai, Nir

Publication type:

Article

Plasma proteomic profile of abdominal obesity in older adults.

Published in:

Obesity (19307381), 2024, v. 32, n. 5, p. 938, doi. 10.1002/oby.24000

By:

Sathyan, Sanish;
Milman, Sofiya;
Ayers, Emmeline;
Gao, Tina;
Verghese, Joe;
Barzilai, Nir

Publication type:

Article

Perinephric and Epididymal Fat Affect Hepatic Metabolism in Rats.

Published in:

Obesity (19307381), 2012, v. 20, n. 1, p. 151, doi. 10.1038/oby.2011.261

By:

Ben-Shlomo, Shani;
Einstein, Francine H.;
Zvibel, Isabel;
Atias, Dikla;
Shlomai, Amir;
Halpern, Zamir;
Barzilai, Nir;
Fishman, Sigal

Publication type:

Article

Genetic Factors in Exceptional Longevity—Reply.

Published in:

2004

By:

Barzilai, Nir;
Atzmon, Gil;
Schechter, Clyde;
Lipton, Richard;
Shuldiner, Alan R.

Publication type:

Letter

Unique Lipoprotein Phenotype and Genotype Associated With Exceptional Longevity.

Published in:

JAMA: Journal of the American Medical Association, 2003, v. 290, n. 15, p. 2030, doi. 10.1001/jama.290.15.2030

By:

Barzilai, Nir;
Atzmon, Gil;
Schechter, Clyde;
Schaefer, Ernst J.;
Cupples, Adrienne L.;
Lipton, Richard;
Cheng, Suzanne;
Shuldiner, Alan R.

Publication type:

Article

Disrupting Mitochondrial–Nuclear Coevolution Affects OXPHOS Complex I Integrity and Impacts Human Health.

Published in:

Genome Biology & Evolution, 2014, v. 6, n. 10, p. 2665, doi. 10.1093/gbe/evu208

By:

Gershoni, Moran;
Levin, Liron;
Ovadia, Ofer;
Toiw, Yasmin;
Shani, Naama;
Dadon, Sara;
Barzilai, Nir;
Bergman, Aviv;
Atzmon, Gil;
Wainstein, Julio;
Tsur, Anat;
Nijtmans, Leo;
Glaser, Benjamin;
Mishmar, Dan

Publication type:

Article

Positive attitude toward life, emotional expression, self-rated health, and depressive symptoms among centenarians and near-centenarians.

Published in:

Aging & Mental Health, 2016, v. 20, n. 9, p. 930, doi. 10.1080/13607863.2015.1056770

By:

Kato, Kaori;
Zweig, Richard;
Schechter, Clyde B.;
Barzilai, Nir;
Atzmon, Gil

Publication type:

Article

Identification of Genes Promoting Skin Youthfulness by Genome-Wide Association Study.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 3, p. 651, doi. 10.1038/jid.2013.381

By:

Chang, Anne L.S.;
Atzmon, Gil;
Bergman, Aviv;
Brugmann, Samantha;
Atwood, Scott X;
Chang, Howard Y;
Barzilai, Nir

Publication type:

Article

Efficacy and Safety of Sitagliptin Versus Glipizide in Patients With Type 2 Diabetes and Moderate-to-Severe Chronic Renal Insufficiency.

Published in:

Diabetes Care, 2013, v. 36, n. 5, p. 1067, doi. 10.2337/dc12-1365

By:

FERREIRA, JUAN CAMILO ARJONA;
MARRE, MICHEL;
BARZILAI, NIR;
HUA GUO;
GOLM, GREGORY T.;
SISK, CHRISTINE MCCRARY;
KAUFMAN, KEITH D.;
GOLDSTEIN, BARRY J.

Publication type:

Article

Statin Therapy and Risk of Developing Type 2 Diabetes: A Meta-Analysis.

Published in:

Diabetes Care, 2009, v. 32, n. 10, p. 1924, doi. 10.2337/dc09-0738

By:

Rajpathak, Swapnil N.;
Kumbhani, Dharam J.;
Crandall, Jill;
Barzilai, Nir;
Alderman, Michael;
Ridker, Paul M.

Publication type:

Article

A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 116, doi. 10.3390/ijms24010116

By:

Bae, Harold;
Gurinovich, Anastasia;
Karagiannis, Tanya T.;
Song, Zeyuan;
Leshchyk, Anastasia;
Li, Mengze;
Andersen, Stacy L.;
Arbeev, Konstantin;
Yashin, Anatoliy;
Zmuda, Joseph;
An, Ping;
Feitosa, Mary;
Giuliani, Cristina;
Franceschi, Claudio;
Garagnani, Paolo;
Mengel-From, Jonas;
Atzmon, Gil;
Barzilai, Nir;
Puca, Annibale;
Schork, Nicholas J.

Publication type:

Article

The place of genetics in ageing research.

Published in:

Nature Reviews Genetics, 2012, v. 13, n. 8, p. 589, doi. 10.1038/nrg3290

By:

Barzilai, Nir;
Guarente, Leonard;
Kirkwood, Thomas B. L.;
Partridge, Linda;
Rando, Thomas A.;
Slagboom, P. Eline

Publication type:

Article

A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations.

Published in:

Frontiers in Genetics, 2021, v. 11, p. 1, doi. 10.3389/fgene.2021.680560

By:

Kim, Seung-Soo;
Hudgins, Adam D.;
Gonzalez, Brenda;
Milman, Sofiya;
Barzilai, Nir;
Vijg, Jan;
Tu, Zhidong;
Suh, Yousin

Publication type:

Article

Creating the Next Generation of Translational Geroscientists.

Published in:

Journal of the American Geriatrics Society, 2019, v. 67, n. 9, p. 1934, doi. 10.1111/jgs.16055

By:

Newman, John C.;
Sokoloski, Julie L.;
Robbins, Paul D.;
Niedernhofer, Laura J.;
Reed, May J.;
Wei, Jeanne;
Austad, Steven N.;
Barzilai, Nir;
Cohen, Harvey Jay;
Kuchel, George A.;
Kirkland, James L.;
Pignolo, Robert J.

Publication type:

Article