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Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment.
- Published in:
- JAMA Neurology, 2024, v. 81, n. 9, p. 947, doi. 10.1001/jamaneurol.2024.2619
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- Publication type:
- Article
Multi-peptide characterization of plasma neurofilament light chain in preclinical and mild Alzheimer's disease.
- Published in:
- Brain Communications, 2024, v. 6, n. 4, p. 1, doi. 10.1093/braincomms/fcae247
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- Publication type:
- Article
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease.
- Published in:
- Brain: A Journal of Neurology, 2023, v. 146, n. 4, p. 1592, doi. 10.1093/brain/awac333
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- Publication type:
- Article
Corrigendum to: CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease.
- Published in:
- 2021
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- Publication type:
- Journal Article
CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Neurofilaments: neurobiological foundations for biomarker applications.
- Published in:
- 2020
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- Publication type:
- journal article
Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset.
- Published in:
- Annals of Neurology, 2024, v. 95, n. 5, p. 951, doi. 10.1002/ana.26891
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- Publication type:
- Article
Suvorexant Acutely Decreases Tau Phosphorylation and Aβ in the Human CNS.
- Published in:
- Annals of Neurology, 2023, v. 94, n. 1, p. 27, doi. 10.1002/ana.26641
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- Publication type:
- Article
Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.
- Published in:
- Annals of Neurology, 2023, v. 93, n. 6, p. 1158, doi. 10.1002/ana.26620
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- Publication type:
- Article
Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid.
- Published in:
- 2020
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- Publication type:
- journal article
MAPT R406W increases tau T217 phosphorylation in absence of amyloid pathology.
- Published in:
- Annals of Clinical & Translational Neurology, 2021, v. 8, n. 9, p. 1817, doi. 10.1002/acn3.51435
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- Publication type:
- Article
Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40478-020-01019-z
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- Publication type:
- Article
Validity of tau as both a biomarker and target for AD and the dynamics of tau over the course of the disease: Tau therapies: From mouse to molecule.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044846
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- Publication type:
- Article
Tau microtubule binding region in cerebrospinal fluid as a biomarker to differentiate tau pathology in Alzheimer's disease: Biomarkers (non‐neuroimaging) / Differential diagnosis.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041644
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- Publication type:
- Article
Tau kinetics in Alzheimer disease and primary tauopathies: Development of new models and analysis methods/tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039109
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- Publication type:
- Article
Mass spectrometry measures of plasma Aβ, tau and P‐tau isoforms' relationship to amyloid PET, tau PET, and clinical stage of Alzheimer's disease: Clinical study results of AD blood biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037518
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- Publication type:
- Article
P4‐299: PHOSPHORYLATION OF SPECIFIC TAU SITES IS ASSOCIATED WITH LOSS OF WHITE MATTER INTEGRITY IN AUTOSOMAL DOMINANT ALZHEIMER DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1404, doi. 10.1016/j.jalz.2019.06.3968
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- Publication type:
- Article
P4‐066: EFFECT OF SLEEP ON CSF TAU AND P‐TAU.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1298, doi. 10.1016/j.jalz.2019.06.3726
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- Publication type:
- Article
F2‐08‐03: EFFECT OF SLEEP ON CSF TAU AND P‐TAU.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P529, doi. 10.1016/j.jalz.2019.06.4446
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- Publication type:
- Article
O1‐01‐02: TAU PHOSPHORYLATION RATES CHANGE FROM BRAIN TO CEREBROSPINAL FLUID AND ARE DIFFERENTIALLY AFFECTED BY ALZHEIMER DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P191, doi. 10.1016/j.jalz.2019.06.4518
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- Publication type:
- Article
IC‐P‐098: PHOSPHORYLATION OF SPECIFIC TAU SITES IS ASSOCIATED WITH LOSS OF WHITE MATTER INTEGRITY IN AUTOSOMAL DOMINANT ALZHEIMER DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P85, doi. 10.1016/j.jalz.2019.06.4941
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- Publication type:
- Article
IC‐P‐098: PHOSPHORYLATION OF SPECIFIC TAU SITES IS ASSOCIATED WITH LOSS OF WHITE MATTER INTEGRITY IN AUTOSOMAL DOMINANT ALZHEIMER DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P85, doi. 10.1016/j.jalz.2019.06.4941
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- Publication type:
- Article
O3‐14‐02: TAU BURDEN MEASURED USING [18F]GTP1 CORRELATES WITH CSF TAU PHOSPHORYLATION AT SITES T217 AND T205 MORE CLOSELY THAN T181.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1059, doi. 10.1016/j.jalz.2018.06.2850
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- Publication type:
- Article
O3‐01‐03: TAU KINETICS IN NEURONS AND IN THE HUMAN CNS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1008, doi. 10.1016/j.jalz.2018.06.2772
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- Publication type:
- Article
P1‐023: MASS SPECTROMETRY–BASED MEASUREMENT OF LONGITUDINAL CSF TAU IDENTIFIES DIFFERENT PHOSPHORYLATED SITES THAT TRACK DISTINCT STAGES OF PRESYMPTOMATIC DOMINANTLY INHERITED AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P273, doi. 10.1016/j.jalz.2018.06.024
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- Publication type:
- Article
HIGHLY SPECIFIC CSF TAU HYPERPHOSPHORYLATION ON T217 OCCURS SIMULTANEOUSLY WITH AMYLOIDOSIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P712, doi. 10.1016/j.jalz.2017.06.911
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- Publication type:
- Article
CSF neurofilament light chain profiling and quantitation in neurological diseases.
- Published in:
- Brain Communications, 2024, v. 6, n. 3, p. 1, doi. 10.1093/braincomms/fcae132
- By:
- Publication type:
- Article
Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer's disease.
- Published in:
- Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae081
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- Publication type:
- Article
A map of neurofilament light chain species in brain and cerebrospinal fluid and alterations in Alzheimer's disease.
- Published in:
- Brain Communications, 2022, v. 4, n. 2, p. 1, doi. 10.1093/braincomms/fcac045
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- Publication type:
- Article
Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios.
- Published in:
- JAMA Neurology, 2023, v. 80, n. 5, p. 516, doi. 10.1001/jamaneurol.2023.0199
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- Publication type:
- Article
Association of BDNF Val66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease.
- Published in:
- JAMA Neurology, 2022, v. 79, n. 3, p. 261, doi. 10.1001/jamaneurol.2021.5181
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- Publication type:
- Article
Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer's Disease.
- Published in:
- Frontiers in Aging Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnagi.2019.00121
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- Publication type:
- Article
Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer's disease and PET amyloid-positive patient identification.
- Published in:
- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00596-4
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- Publication type:
- Article
Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal‐dominant Alzheimer's disease.
- Published in:
- Aging Cell, 2023, v. 22, n. 8, p. 1, doi. 10.1111/acel.13871
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- Publication type:
- Article
E2814: an anti‐tau therapy engages its CNS target and affects the downstream tangle‐specific biomarker MTBR‐tau243 in Dominantly Inherited Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082771
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- Publication type:
- Article
Prediction of continuous amyloid PET values by CSF tau measures.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078808
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- Publication type:
- Article
A machine learning examination of the utility of CSF, neuroimaging, and plasma biomarkers in late onset Alzheimer Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070918
- By:
- Publication type:
- Article
Associations of plasma pT205/T205 with Alzheimer's disease pathology and cognitive function: a comparison with pT217/T217 and pT181/T181.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079523
- By:
- Publication type:
- Article
Blood‐based biomarkers of Alzheimer disease as measured by a mass spectrometry assay are as accurate as CSF tests.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070428
- By:
- Publication type:
- Article
Development of a targeted proteomic assay for the quantitation of neurofilament light in cerebrospinal fluid: Correlation with Simoa‐based quantitation across neurodegenerative diseases and centres.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079668
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- Publication type:
- Article
Plasma tau phosphorylation at T217 predicts amyloid deposition in dominantly inherited and late onset Alzheimer disease participants without clinical symptoms.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079220
- By:
- Publication type:
- Article
CSF Plasminogen inhibitor 1(PAI‐1) levels are associated with dementia symptoms in Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078567
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- Publication type:
- Article
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075367
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- Publication type:
- Article
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081678
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- Publication type:
- Article
Acute sleep loss decreases CSF‐to‐blood clearance of Alzheimer's disease biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 7, p. 3055, doi. 10.1002/alz.12930
- By:
- Publication type:
- Article
Comprehensive CSF Tau Profiling Identifies Soluble Tau Pathophysiological Stages in Dominantly Inherited Alzheimer Network (DIAN): Implications for the DIAN‐TU Tau Next Generation Platform.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.065313
- By:
- Publication type:
- Article
The relationship of soluble p‐tau isoforms with brain amyloid and tau deposition in sporadic AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.067885
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- Publication type:
- Article
CSF tau phosphorylation at sites 217 and 205 mediate the relationship between PET amyloid and downstream AD markers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.065718
- By:
- Publication type:
- Article
CSF tau phosphorylation at sites 217 and 181 are associated with preclinical and biphasic alterations in resting‐state functional connectivity in Autosomal Dominant AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.065641
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- Publication type:
- Article
CSF tau phosphorylation occupancy at t217 increases in MAPT R406W mutation carriers without amyloid pathology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.055533
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- Publication type:
- Article