Works matching AU Barth, Holger

Results: 105

The antimicrobial peptide Angie 5 inhibits TcdA and TcdB from Clostridioides difficile.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05799-2

By:

Lietz, Stefanie;
Sokolowski, Lena-Marie;
Lindner, Katrin;
Rodríguez, Armando A.;
Ständker, Ludger;
Vogel, Verena;
Spellerberg, Barbara;
Stenger, Steffen;
Alpízar-Pedraza, Daniel;
Ernst, Katharina;
Papatheodorou, Panagiotis;
Barth, Holger

Publication type:

Article

Programmable Biopolymers for Advancing Biomedical Applications of Fluorescent Nanodiamonds.

Published in:

Advanced Functional Materials, 2015, v. 25, n. 42, p. 6576, doi. 10.1002/adfm.201502704

By:

Wu, Yuzhou;
Ermakova, Anna;
Liu, Weina;
Pramanik, Goutam;
Vu, Tran Minh;
Kurz, Andrea;
McGuinness, Liam;
Naydenov, Boris;
Hafner, Susanne;
Reuter, Rolf;
Wrachtrup, Joerg;
Isoya, Junichi;
Förtsch, Christina;
Barth, Holger;
Simmet, Thomas;
Jelezko, Fedor;
Weil, Tanja

Publication type:

Article

Biopolymers: Programmable Biopolymers for Advancing Biomedical Applications of Fluorescent Nanodiamonds (Adv. Funct. Mater. 42/2015).

Published in:

Advanced Functional Materials, 2015, v. 25, n. 42, p. 6558, doi. 10.1002/adfm.201570270

By:

Wu, Yuzhou;
Ermakova, Anna;
Liu, Weina;
Pramanik, Goutam;
Vu, Tran Minh;
Kurz, Andrea;
McGuinness, Liam;
Naydenov, Boris;
Hafner, Susanne;
Reuter, Rolf;
Wrachtrup, Joerg;
Isoya, Junichi;
Förtsch, Christina;
Barth, Holger;
Simmet, Thomas;
Jelezko, Fedor;
Weil, Tanja

Publication type:

Article

Programmable Biopolymers for Advancing Biomedical Applications of Fluorescent Nanodiamonds.

Published in:

Advanced Functional Materials, 2015, p. 6576, doi. 10.1002/adfm.201502704

By:

Yuzhou Wu;
Ermakova, Anna;
Weina Liu;
Pramanik, Goutam;
Vu, Tran Minh;
Kurz, Andrea;
McGuinness, Liam;
Naydenov, Boris;
Hafner, Susanne;
Reuter, Rolf;
Wrachtrup, Joerg;
Isoya, Junichi;
Förtsch, Christina;
Barth, Holger;
Simmet, Thomas;
Jelezko, Fedor;
Weil, Tanja

Publication type:

Article

Actin Microfilaments Facilitate the Retrograde Transport from the Golgi Complex to the Endoplasmic Reticulum in Mammalian Cells.

Published in:

Traffic, 2001, v. 2, n. 10, p. 717, doi. 10.1034/j.1600-0854.2001.21006.x

By:

Valderrama, Ferran;
M. Durán, Juan;
Babià, Teresa;
Barth, Holger;
Renau-Piqueras, Jaime;
Egea, Gustavo

Publication type:

Article

Sich berufl ich und persönlich weiterentwickeln, an Sichtbarkeit gewinnen und Wissen teilen - mit dem Mentoring-Programm der GPM.

Published in:

Projekt-Management Aktuell, 2022, v. 33, n. 3, p. 68, doi. 10.24053/PM-2022-0058

By:

Robst, Mentee Dominik;
Barth, Mentor Holger

Publication type:

Article

Vom Reagenzglas in die Zelle.

Published in:

Nachrichten aus der Chemie, 2018, v. 66, n. 12, p. 1146, doi. 10.1002/nadc.20184077496

By:

Ziener, Ulrich;
Barth, Holger

Publication type:

Article

The Antibiotic Bacitracin Protects Human Intestinal Epithelial Cells and Stem Cell-Derived Intestinal Organoids from Clostridium difficile Toxin TcdB.

Published in:

Stem Cells International, 2019, p. 1, doi. 10.1155/2019/4149762

By:

Zhu, Ziyu;
Schnell, Leonie;
Müller, Bastian;
Müller, Martin;
Papatheodorou, Panagiotis;
Barth, Holger

Publication type:

Article

Mitotic entry elucidated with bacterial toxin toolbox.

Published in:

Cell Cycle, 2014, v. 13, n. 14, p. 2159, doi. 10.4161/cc.29465

By:

Barth, Holger;
Johnsson, Nils

Publication type:

Article

The enzyme subunit SubA of Shiga toxin-producing E. coli strains demonstrates comparable intracellular transport and cytotoxic activity as the holotoxin SubAB in HeLa and HCT116 cells in vitro.

Published in:

Archives of Toxicology, 2021, v. 95, n. 3, p. 975, doi. 10.1007/s00204-020-02965-2

By:

Sessler, Katharina;
Papatheodorou, Panagiotis;
Wondany, Fanny;
Krause, Maike;
Noettger, Sabrina;
Bernhard, Denise;
Michaelis, Jens;
Schmidt, Herbert;
Barth, Holger

Publication type:

Article

Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro.

Published in:

Archives of Toxicology, 2020, v. 94, n. 5, p. 1753, doi. 10.1007/s00204-020-02731-4

By:

Fellermann, Maximilian;
Wondany, Fanny;
Carle, Stefan;
Nemeth, Julia;
Sadhanasatish, Tanmay;
Frick, Manfred;
Barth, Holger;
Michaelis, Jens

Publication type:

Article

Clostridial C3 toxins target monocytes/macrophages and modulate their functions.

Published in:

Frontiers in Immunology, 2015, p. 1, doi. 10.3389/fimmu.2015.00339

By:

Barth, Holger;
Fischer, Stephan;
Möglich, Amelie;
Förtsch, Christina

Publication type:

Article

The C2-streptavidin delivery system promotes the uptake of biotinylated molecules in macrophages and T-leukemia cells.

Published in:

Biological Chemistry, 2010, v. 391, n. 12, p. 1315, doi. 10.1515/BC.2010.132

By:

Fahrer, Jörg;
Rieger, Julia;
van Zandbergen, Ger;
Barth, Holger

Publication type:

Article

The C2-streptavidin delivery system promotes the uptake of biotinylated molecules in macrophages and T-leukemia cells.

Published in:

Biological Chemistry, 2010, v. 391, n. 11, p. 1315, doi. 10.1515/BC.2010.132

By:

Fahrer, Jörg;
Rieger, Julia;
van Zandbergen, Ger;
Barth, Holger

Publication type:

Article

Atomic force and infrared spectroscopic studies on the role of surface charge for the anti-biofouling properties of polydopamine films.

Published in:

Analytical & Bioanalytical Chemistry, 2023, v. 415, n. 11, p. 2059, doi. 10.1007/s00216-022-04431-7

By:

Caniglia, Giada;
Teuber, Andrea;
Barth, Holger;
Mizaikoff, Boris;
Kranz, Christine

Publication type:

Article

A Supramolecular Approach toward Bioinspired PAMAM-Dendronized Fusion Toxins.

Published in:

Macromolecular Bioscience, 2016, v. 16, n. 6, p. 803, doi. 10.1002/mabi.201500417

By:

Kuan, Seah Ling;
Förtsch, Christina;
Ng, David Yuen Wah;
Fischer, Stephan;
Tokura, Yu;
Liu, Weina;
Wu, Yuzhou;
Koynov, Kaloian;
Barth, Holger;
Weil, Tanja

Publication type:

Article

Macromol. Biosci. 6/2016.

Published in:

Macromolecular Bioscience, 2016, v. 16, n. 6, p. 785, doi. 10.1002/mabi.201670022

By:

Kuan, Seah Ling;
Förtsch, Christina;
Ng, David Yuen Wah;
Fischer, Stephan;
Tokura, Yu;
Liu, Weina;
Wu, Yuzhou;
Koynov, Kaloian;
Barth, Holger;
Weil, Tanja

Publication type:

Article

Prognostic impact of polypharmacy and drug interactions in patients with advanced cancer.

Published in:

2019

By:

Hoemme, Alexander;
Barth, Holger;
Haschke, Manuel;
Krähenbühl, Stephan;
Strasser, Florian;
Lehner, Claudia;
von Kameke, Alexander;
Wälti, Thomas;
Thürlimann, Beat;
Früh, Martin;
Driessen, Christoph;
Joerger, Markus

Publication type:

journal article

The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.784856

By:

Papatheodorou, Panagiotis;
Kindig, Selina;
Badilla-Lobo, Adriana;
Fischer, Stephan;
Durgun, Ebru;
Thuraisingam, Tharani;
Witte, Alexander;
Song, Shuo;
Aktories, Klaus;
Chaves-Olarte, Esteban;
Rodríguez, César;
Barth, Holger

Publication type:

Article

Efficient Delivery of p53 and Cytochrome C by Supramolecular Assembly of a Dendritic Multi-Domain Delivery System.

Published in:

Advanced Healthcare Materials, 2013, v. 2, n. 12, p. 1620, doi. 10.1002/adhm.201200419

By:

Ng, David Yuen Wah;
Fahrer, Jörg;
Wu, Yuzhou;
Eisele, Klaus;
Kuan, Seah Ling;
Barth, Holger;
Weil, Tanja

Publication type:

Article

Inhibition of Pertussis Toxin by Human α-Defensins-1 and -5: Differential Mechanisms of Action.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10557, doi. 10.3390/ijms241310557

By:

Kling, Carolin;
Sommer, Anja;
Almeida-Hernandez, Yasser;
Rodríguez, Armando;
Perez-Erviti, Julio A.;
Bhadane, Rajendra;
Ständker, Ludger;
Wiese, Sebastian;
Barth, Holger;
Pupo-Meriño, Mario;
Pulliainen, Arto T.;
Sánchez-García, Elsa;
Ernst, Katharina

Publication type:

Article

Human α-Defensin-6 Neutralizes Clostridioides difficile Toxins TcdA and TcdB by Direct Binding.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4509, doi. 10.3390/ijms23094509

By:

Barthold, Lara;
Heber, Sebastian;
Schmidt, Christoph Q.;
Gradl, Marion;
Weidinger, Gilbert;
Barth, Holger;
Fischer, Stephan

Publication type:

Article

Bacillus anthracis' PA63 Delivers the Tumor Metastasis Suppressor Protein NDPK-A/NME1 into Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 9, p. 3295, doi. 10.3390/ijms21093295

By:

Felix, Ina;
Lomada, Santosh K.;
Barth, Holger;
Wieland, Thomas

Publication type:

Article

Exploring the role of host cell chaperones/PPIases during cellular up-take of bacterial ADP-ribosylating toxins as basis for novel pharmacological strategies to protect mammalian cells against these virulence factors.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2011, v. 383, n. 3, p. 237, doi. 10.1007/s00210-010-0581-y

By:

Barth, Holger

Publication type:

Article

Internalization of biotinylated compounds into cancer cells is promoted by a molecular Trojan horse based upon core streptavidin and clostridial C2 toxin.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2011, v. 383, n. 3, p. 263, doi. 10.1007/s00210-010-0585-7

By:

Fahrer, Jörg;
Funk, Joschua;
Lillich, Maren;
Barth, Holger

Publication type:

Article

The uptake machinery of clostridial actin ADP-ribosylating toxins – a cell delivery system for fusion proteins and polypeptide drugs.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, v. 366, n. 6, p. 501, doi. 10.1007/s00210-002-0626-y

By:

Barth, Holger;
Blöcker, Dagmar;
Aktories, Klaus

Publication type:

Article

Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.

Published in:

Journal of Physiology, 1999, v. 516, n. 1, p. 67, doi. 10.1111/j.1469-7793.1999.067aa.x

By:

Nilius, Bernd;
Voets, Thomas;
Prenen, Jean;
Barth, Holger;
Aktories, Klaus;
Kaibuchi, Kozo;
Droogmans, Guy;
Eggermont, Jan

Publication type:

Article

Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01204

By:

Korbmacher, Michael;
Fischer, Stephan;
Landenberger, Marc;
Papatheodorou, Panagiotis;
Aktories, Klaus;
Barth, Holger

Publication type:

Article

Exploring the inhibitory potential of the antiarrhythmic drug amiodarone against Clostridioides difficile toxins TcdA and TcdB.

Published in:

Gut Microbes, 2023, v. 15, n. 2, p. 1, doi. 10.1080/19490976.2023.2256695

By:

Schumacher, Judith;
Nienhaus, Astrid;
Heber, Sebastian;
Matylitsky, Jauheni;
Chaves-Olarte, Esteban;
Rodríguez, César;
Barth, Holger;
Papatheodorou, Panagiotis

Publication type:

Article

The Pore-Forming Subunit C2IIa of the Binary Clostridium botulinum C2 Toxin Reduces the Chemotactic Translocation of Human Polymorphonuclear Leukocytes.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.810611

By:

Eisele, Julia;
Schreiner, Simone;
Borho, Joscha;
Fischer, Stephan;
Heber, Sebastian;
Endres, Sascha;
Fellermann, Maximilian;
Wohlgemuth, Lisa;
Huber-Lang, Markus;
Fois, Giorgio;
Fauler, Michael;
Frick, Manfred;
Barth, Holger

Publication type:

Article

Inhibition of Clostridioides difficile Toxins TcdA and TcdB by Ambroxol.

Published in:

Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.809595

By:

Heber, Sebastian;
Barthold, Lara;
Baier, Jan;
Papatheodorou, Panagiotis;
Fois, Giorgio;
Frick, Manfred;
Barth, Holger;
Fischer, Stephan

Publication type:

Article

Das IRS-Werkstattgespräch — Netzwerk einer transdisziplinären und kommunikativen Stadtgeschichtsforschung.

Published in:

Raumforschung und Raumordnung, 2000, v. 58, n. 5, p. 418, doi. 10.1007/BF03182932

By:

Barth, Holger

Publication type:

Article

Croconaine‐Based Polymer Particles as Contrast Agents for Photoacoustic Imaging.

Published in:

Macromolecular Rapid Communications, 2020, v. 41, n. 22, p. 1, doi. 10.1002/marc.202000418

By:

Jansen, Felicitas;
Lamla, Markus;
Mauthe, Diana;
Fischer, Stephan;
Barth, Holger;
Kuehne, Alexander J. C.

Publication type:

Article

Autonomous Ultrafast Self‐Healing Hydrogels by pH‐Responsive Functional Nanofiber Gelators as Cell Matrices.

Published in:

Advanced Materials, 2019, v. 31, n. 2, p. N.PAG, doi. 10.1002/adma.201805044

By:

Gačanin, Jasmina;
Hedrich, Jana;
Sieste, Stefanie;
Glaßer, Gunnar;
Lieberwirth, Ingo;
Schilling, Corinna;
Fischer, Stephan;
Barth, Holger;
Knöll, Bernd;
Synatschke, Christopher V.;
Weil, Tanja

Publication type:

Article

Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo.

Published in:

Archives of Toxicology, 2018, v. 92, n. 1, p. 323, doi. 10.1007/s00204-017-2058-y

By:

Martin, Tobias;
Möglich, Amelie;
Felix, Ina;
Förtsch, Christina;
Rittlinger, Anne;
Palmer, Annette;
Denk, Stephanie;
Schneider, Julian;
Notbohm, Lena;
Vogel, Mona;
Geiger, Hartmut;
Paschke, Stephan;
Huber-Lang, Markus;
Barth, Holger

Publication type:

Article

Chloroquine derivatives block the translocation pores and inhibit cellular entry of Clostridium botulinum C2 toxin and Bacillus anthracis lethal toxin.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1431, doi. 10.1007/s00204-016-1716-9

By:

Kreidler, Anna-Maria;
Benz, Roland;
Barth, Holger

Publication type:

Article

In situ monitoring of Lentilactobacillus parabuchneri biofilm formation via real-time infrared spectroscopy.

Published in:

NPJ Biofilms & Microbiomes, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41522-022-00353-5

By:

Bajrami, Diellza;
Fischer, Stephan;
Barth, Holger;
Sarquis, María A.;
Ladero, Victor M.;
Fernández, María;
Sportelli, Maria. C.;
Cioffi, Nicola;
Kranz, Christine;
Mizaikoff, Boris

Publication type:

Article

Wenn Fürsorge zu Ausgrenzung führt: Zehn Jahre Erfahrungen in der psychosozialen Arbeit.

Published in:

Sozialpsychiatrische Informationen, 2021, v. 51, n. 4, p. 43, doi. 10.5771/0171-4538-2021-4-43

By:

Barth, Holger

Publication type:

Article

The Chaperonin TRiC/CCT Inhibitor HSF1A Protects Cells from Intoxication with Pertussis Toxin.

Published in:

Toxins, 2024, v. 16, n. 1, p. 36, doi. 10.3390/toxins16010036

By:

Jia, Jinfang;
Zoeschg, Manuel;
Barth, Holger;
Pulliainen, Arto T.;
Ernst, Katharina

Publication type:

Article

Domperidone Inhibits Clostridium botulinum C2 Toxin and Bordetella pertussis Toxin.

Published in:

Toxins, 2023, v. 15, n. 7, p. 412, doi. 10.3390/toxins15070412

By:

Jia, Jinfang;
Braune-Yan, Maria;
Lietz, Stefanie;
Wahba, Mary;
Pulliainen, Arto T.;
Barth, Holger;
Ernst, Katharina

Publication type:

Article

The Clostridium botulinum C2 Toxin Subunit C2IIa Delivers Enzymes with Positively Charged N-Termini into the Cytosol of Target Cells.

Published in:

Toxins, 2023, v. 15, n. 6, p. 390, doi. 10.3390/toxins15060390

By:

Heber, Sebastian;
Borho, Joscha;
Stadler, Nicole;
Wondany, Fanny;
König, Irina;
Michaelis, Jens;
Papatheodorou, Panagiotis;
Barth, Holger;
Fellermann, Maximilian

Publication type:

Article

Domperidone Protects Cells from Intoxication with Clostridioides difficile Toxins by Inhibiting Hsp70-Assisted Membrane Translocation.

Published in:

Toxins, 2023, v. 15, n. 6, p. 384, doi. 10.3390/toxins15060384

By:

Braune-Yan, Maria;
Jia, Jinfang;
Wahba, Mary;
Schmid, Johannes;
Papatheodorou, Panagiotis;
Barth, Holger;
Ernst, Katharina

Publication type:

Article

Clostridium botulinum C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages.

Published in:

Toxins, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/toxins14100711

By:

Fellermann, Maximilian;
Stemmer, Mia;
Noschka, Reiner;
Wondany, Fanny;
Fischer, Stephan;
Michaelis, Jens;
Stenger, Steffen;
Barth, Holger

Publication type:

Article

The chaperone Hsp90 and PPIases of the cyclophilin and FKBP families facilitate membrane translocation of P hotorhabdus luminescens ADP-ribosyltransferases.

Published in:

Cellular Microbiology, 2014, v. 16, n. 4, p. 490, doi. 10.1111/cmi.12228

By:

Lang, Alexander E.;
Ernst, Katharina;
Lee, Haram;
Papatheodorou, Panagiotis;
Schwan, Carsten;
Barth, Holger;
Aktories, Klaus

Publication type:

Article

FK506-binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells.

Published in:

Cellular Microbiology, 2012, v. 14, n. 8, p. 1193, doi. 10.1111/j.1462-5822.2012.01788.x

By:

Kaiser, Eva;
Böhm, Natalie;
Ernst, Katharina;
Langer, Simon;
Schwan, Carsten;
Aktories, Klaus;
Popoff, Michel;
Fischer, Gunter;
Barth, Holger

Publication type:

Article

Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen.

Published in:

Cellular Microbiology, 2011, v. 13, n. 3, p. 359, doi. 10.1111/j.1462-5822.2010.01539.x

By:

Dmochewitz, Lydia;
Lillich, Maren;
Kaiser, Eva;
Jennings, Laura D.;
Lang, Alexander E.;
Buchner, Johannes;
Fischer, Gunter;
Aktories, Klaus;
Collier, R. John;
Barth, Holger

Publication type:

Article

Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms S. Pust, H. Barth and K. Sandvig Endocytic mechanisms underlying C2 toxin uptake.

Published in:

Cellular Microbiology, 2010, v. 12, n. 12, p. 1809, doi. 10.1111/j.1462-5822.2010.01512.x

By:

Pust, Sascha;
Barth, Holger;
Sandvig, Kirsten

Publication type:

Article

Selective and specific internalization of clostridial C3 ADP-ribosyltransferases into macrophages and monocytes.

Published in:

Cellular Microbiology, 2010, v. 12, n. 2, p. 233, doi. 10.1111/j.1462-5822.2009.01393.x

By:

Fahrer, Jörg;
Kuban, Jasmin;
Heine, Karin;
Rupps, Gabriel;
Kaiser, Eva;
Felder, Edward;
Benz, Roland;
Barth, Holger

Publication type:

Article

Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells.

Published in:

Cellular Microbiology, 2009, v. 11, n. 5, p. 780, doi. 10.1111/j.1462-5822.2009.01291.x

By:

Kaiser, Eva;
Pust, Sascha;
Kroll, Claudia;
Barth, Holger

Publication type:

Article

Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02020-2

By:

Ng, David Y. W.;
Vill, Roman;
Yuzhou Wu;
Koynov, Kaloian;
Yu Tokura;
Weina Liu;
Sihler, Susanne;
Kreyes, Andreas;
Ritz, Sandra;
Barth, Holger;
Ziener, Ulrich;
Weil, Tanja

Publication type:

Article