Works by Barroso, Inês

Results: 67
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    Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

    Published in:
    Nature Genetics, 2015, v. 47, n. 11, p. 1282, doi. 10.1038/ng.3405
    By:
    • Loh, Marie;
    • Zhang, Weihua;
    • Saleheen, Danish;
    • Wahl, Simone;
    • Tan, Sian-Tsung;
    • Scott, William R;
    • Afzal, Uzma;
    • Ahluwalia, Tarunveer S;
    • Esko, Tõnu;
    • Harris, Sarah E;
    • Hartiala, Jaana;
    • Khor, Chiea-Chuen;
    • Stewart, Alexandre F R;
    • Wu, Jer-Yuarn;
    • Zhang, Yi;
    • Lyytikäinen, Leo-Pekka;
    • Postmus, Iris;
    • Raitakari, Olli T;
    • Traglia, Michela;
    • Barroso, Inês
    Publication type:
    Article
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    Meta-analysis and imputation refines the association of 15q25 with smoking quantity.

    Published in:
    Nature Genetics, 2010, v. 42, n. 5, p. 436, doi. 10.1038/ng.572
    By:
    • Liu, Jason Z.;
    • Tozzi, Federica;
    • Waterworth, Dawn M.;
    • Pillai, Sreekumar G.;
    • Muglia, Pierandrea;
    • Middleton, Lefkos;
    • Berrettini, Wade;
    • Knouff, Christopher W.;
    • Xin Yuan;
    • Waeber, Gérard;
    • Vollenweider, Peter;
    • Preisig, Martin;
    • Wareham, Nicholas J.;
    • Jing Hua Zhao;
    • Loos, Ruth J F.;
    • Barroso, Inês;
    • Kay-Tee Khaw;
    • Grundy, Scott;
    • Barter, Philip;
    • Mahley, Robert
    Publication type:
    Article
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    Genome-wide association study identifies five loci associated with lung function.

    Published in:
    Nature Genetics, 2010, v. 42, n. 1, p. 36, doi. 10.1038/ng.501
    By:
    • Repapi, Emmanouela;
    • Sayers, Ian;
    • Wain, Louise V.;
    • Burton, Paul R.;
    • Johnson, Toby;
    • Obeidat, Ma'en;
    • Jing Hua Zhao;
    • Ramasamy, Adaikalavan;
    • Guangju Zhai;
    • Vitart, Veronique;
    • Huffman, Jennifer E.;
    • Igl, Wilmar;
    • Albrecht, Eva;
    • Deloukas, Panos;
    • Henderson, John;
    • Granell, Raquel;
    • McArdle, Wendy L.;
    • Rudnicka, Alicja R.;
    • Barroso, Inês;
    • Loos, Ruth J. F.
    Publication type:
    Article
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    Digenic inheritance of severe insulin resistance in a human pedigree.

    Published in:
    Nature Genetics, 2002, v. 31, n. 4, p. 379, doi. 10.1038/ng926
    By:
    • Savage, David B.;
    • Agostini, Maura;
    • Barroso, Inês;
    • Gurnell, Mark;
    • Luan, Jian'an;
    • Meirhaeghe, Aline;
    • Harding, Anne-Helen;
    • Ihrke, Gudrun;
    • Rajanayagam, Odelia;
    • Soos, Maria A.;
    • George, Stella;
    • Berger, Dirk;
    • Thomas, E. Louise;
    • Bell, Jimmy D.;
    • Meeran, Karim;
    • Ross, Richard J.;
    • Vidal-Puig, Antonio;
    • Wareham, Nicholas J.;
    • O'Rahilly, Stephen;
    • Chatterjee, V. Krishna K.
    Publication type:
    Article
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    Genome-wide association study of type 2 diabetes in Africa.

    Published in:
    Diabetologia, 2019, v. 62, n. 7, p. 1204, doi. 10.1007/s00125-019-4880-7
    By:
    • Chen, Ji;
    • Sun, Meng;
    • Adeyemo, Adebowale;
    • Pirie, Fraser;
    • Carstensen, Tommy;
    • Pomilla, Cristina;
    • Doumatey, Ayo P.;
    • Chen, Guanjie;
    • Young, Elizabeth H.;
    • Sandhu, Manjinder;
    • Morris, Andrew P.;
    • Barroso, Inês;
    • McCarthy, Mark I.;
    • Mahajan, Anubha;
    • Wheeler, Eleanor;
    • Rotimi, Charles N.;
    • Motala, Ayesha A.
    Publication type:
    Article
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    Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04436-9
    By:
    • Kuchenbaecker, Karoline;
    • Gilly, Arthur;
    • Suveges, Daniel;
    • Southam, Lorraine;
    • Giannakopoulou, Olga;
    • Kilian, Britt;
    • Tsafantakis, Emmanouil;
    • Karaleftheri, Maria;
    • Farmaki, Aliki-Eleni;
    • Gurdasani, Deepti;
    • Kundu, Kousik;
    • Sandhu, Manjinder S.;
    • Danesh, John;
    • Butterworth, Adam;
    • Barroso, Inês;
    • Dedoussis, George;
    • Zeggini, Eleftheria
    Publication type:
    Article
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    The influence of rare variants in circulating metabolic biomarkers.

    Published in:
    PLoS Genetics, 2020, v. 16, n. 3, p. 1, doi. 10.1371/journal.pgen.1008605
    By:
    • Riveros-Mckay, Fernando;
    • Oliver-Williams, Clare;
    • Karthikeyan, Savita;
    • Walter, Klaudia;
    • Kundu, Kousik;
    • Ouwehand, Willem H.;
    • Roberts, David;
    • Di Angelantonio, Emanuele;
    • Soranzo, Nicole;
    • Danesh, John;
    • Wheeler, Eleanor;
    • Zeggini, Eleftheria;
    • Butterworth, Adam S.;
    • Barroso, Inês
    Publication type:
    Article
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    Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.

    Published in:
    2022
    By:
    • Murphy, Neil;
    • Song, Mingyang;
    • Papadimitriou, Nikos;
    • Carreras-Torres, Robert;
    • Langenberg, Claudia;
    • Martin, Richard M;
    • Tsilidis, Konstantinos K;
    • Barroso, Inês;
    • Chen, Ji;
    • Frayling, Timothy M;
    • Bull, Caroline J;
    • Vincent, Emma E;
    • Cotterchio, Michelle;
    • Gruber, Stephen B;
    • Pai, Rish K;
    • Newcomb, Polly A;
    • Perez-Cornago, Aurora;
    • Duijnhoven, Franzel J B van;
    • Guelpen, Bethany Van;
    • Vodicka, Pavel
    Publication type:
    journal article
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    Homozygous loss-of-function variants in European cosmopolitan and isolate populations.

    Published in:
    Human Molecular Genetics, 2015, v. 24, n. 19, p. 5464, doi. 10.1093/hmg/ddv272
    By:
    • Kaiser, Vera B.;
    • Svinti, Victoria;
    • Prendergast, James G.;
    • You-Ying Chau;
    • Campbell, Archie;
    • Patarcic, Inga;
    • Barroso, Inês;
    • Joshi, Peter K.;
    • Hastie, Nicholas D.;
    • Miljkovic, Ana;
    • Taylor, Martin S.;
    • Scotland, Generation;
    • Enroth, Stefan;
    • Memari, Yasin;
    • Kolb-Kokocinski, Anja;
    • Wright, Alan F.;
    • Gyllensten, Ulf;
    • Durbin, Richard;
    • Rudan, Igor;
    • Campbell, Harry
    Publication type:
    Article
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    Hypoinsulinaemic, hypoketotic hypoglycaemia due to mosaic genetic activation of PI3-kinase.

    Published in:
    European Journal of Endocrinology, 2017, v. 177, n. 2, p. 175, doi. 10.1530/EJE-17-0132
    By:
    • Leiter, Sarah M.;
    • Parker, Victoria E. R.;
    • Welters, Alena;
    • Knox, Rachel;
    • Rocha, Nuno;
    • Clark, Graeme;
    • Payne, Felicity;
    • Lotta, Luca;
    • Harris, Julie;
    • Guerrero-Fernández, Julio;
    • González-Casado, Isabel;
    • García-Miñaur, Sixto;
    • Gordo, Gema;
    • Wareham, Nick;
    • Martínez-Glez, Víctor;
    • Allison, Michael;
    • O’Rahilly, Stephen;
    • Barroso, Inês;
    • Meissner, Thomas;
    • Davies, Susan
    Publication type:
    Article
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    Human SH2B1 mutations are associated with maladaptive behaviors and obesity.

    Published in:
    Journal of Clinical Investigation, 2012, v. 122, n. 12, p. 4732, doi. 10.1172/JCI62696
    By:
    • Doche, Michael E.;
    • Bochukova, Elena G.;
    • Hsiao-Wen Su;
    • Pearce, Laura R.;
    • Keogh, Julia M.;
    • Henning, Elana;
    • Cline, Joel M.;
    • Dale, Anne;
    • Cheetham, Tim;
    • Barroso, Inês;
    • Argetsinger, Lawrence S.;
    • O'Rahilly, Stephen;
    • Liangyou Rui;
    • Christin Carter-Su;
    • Farooqi, I. Sadaf
    Publication type:
    Article
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    Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07730-9
    By:
    • Gilly, Arthur;
    • Suveges, Daniel;
    • Kuchenbaecker, Karoline;
    • Pollard, Martin;
    • Southam, Lorraine;
    • Hatzikotoulas, Konstantinos;
    • Farmaki, Aliki-Eleni;
    • Bjornland, Thea;
    • Waples, Ryan;
    • Appel, Emil V. R.;
    • Casalone, Elisabetta;
    • Melloni, Giorgio;
    • Kilian, Britt;
    • Rayner, Nigel W.;
    • Ntalla, Ioanna;
    • Kundu, Kousik;
    • Walter, Klaudia;
    • Danesh, John;
    • Butterworth, Adam;
    • Barroso, Inês
    Publication type:
    Article
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    Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07070-8
    By:
    • Gilly, Arthur;
    • Suveges, Daniel;
    • Kuchenbaecker, Karoline;
    • Pollard, Martin;
    • Southam, Lorraine;
    • Hatzikotoulas, Konstantinos;
    • Farmaki, Aliki-Eleni;
    • Bjornland, Thea;
    • Waples, Ryan;
    • Appel, Emil V. R.;
    • Casalone, Elisabetta;
    • Melloni, Giorgio;
    • Kilian, Britt;
    • Rayner, Nigel W.;
    • Ntalla, Ioanna;
    • Kundu, Kousik;
    • Walter, Klaudia;
    • Danesh, John;
    • Butterworth, Adam;
    • Barroso, Inês
    Publication type:
    Article
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    Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities.

    Published in:
    Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65531-x
    By:
    • Sonoyama, Takuhiro;
    • Stadler, Lukas K. J.;
    • Zhu, Mingyan;
    • Keogh, Julia M.;
    • Henning, Elana;
    • Hisama, Fuki;
    • Kirwan, Peter;
    • Jura, Magdalena;
    • Blaszczyk, Beata K.;
    • DeWitt, David C.;
    • Brouwers, Bas;
    • Hyvönen, Marko;
    • Barroso, Inês;
    • Merkle, Florian T.;
    • Appleyard, Suzanne M.;
    • Wayman, Gary A.;
    • Farooqi, I. Sadaf
    Publication type:
    Article
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    Hyperglycaemia is a causal risk factor for upper limb pathologies.

    Published in:
    International Journal of Epidemiology, 2024, v. 53, n. 1, p. 1, doi. 10.1093/ije/dyad187
    By:
    • Green, Harry D;
    • Burden, Ella;
    • Chen, Ji;
    • Evans, Jonathan;
    • Patel, Kashyap;
    • Wood, Andrew R;
    • Beaumont, Robin N;
    • Tyrrell, Jessica;
    • Frayling, Timothy M;
    • Hattersley, Andrew T;
    • Oram, Richard A;
    • Bowden, Jack;
    • Barroso, Inês;
    • Smith, Christopher;
    • Weedon, Michael N
    Publication type:
    Article
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    Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17696-2
    By:
    • Sallah, Neneh;
    • Miley, Wendell;
    • Labo, Nazzarena;
    • Carstensen, Tommy;
    • Fatumo, Segun;
    • Gurdasani, Deepti;
    • Pollard, Martin O.;
    • Dilthey, Alexander T.;
    • Mentzer, Alexander J.;
    • Marshall, Vickie;
    • Cornejo Castro, Elena M.;
    • Pomilla, Cristina;
    • Young, Elizabeth H.;
    • Asiki, Gershim;
    • Hibberd, Martin L.;
    • Sandhu, Manjinder;
    • Kellam, Paul;
    • Newton, Robert;
    • Whitby, Denise;
    • Barroso, Inês
    Publication type:
    Article
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    Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.

    Published in:
    Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 4, p. 1065, doi. 10.1210/clinem/dgab877
    By:
    • Koprulu, Mine;
    • Zhao, Yajie;
    • Wheeler, Eleanor;
    • Dong, Liang;
    • Rocha, Nuno;
    • Li, Chen;
    • Griffin, John D.;
    • Patel, Satish;
    • de Streek, Marcel Van;
    • Glastonbury, Craig A.;
    • Stewart, Isobel D.;
    • Day, Felix R.;
    • Luan, Jian’an;
    • Bowker, Nicholas;
    • Wittemans, Laura B. L.;
    • Kerrison, Nicola D.;
    • Cai, Lina;
    • Lucarelli, Debora M. E.;
    • Barroso, Inês;
    • McCarthy, Mark I.
    Publication type:
    Article
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    Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4028, doi. 10.1172/JCI73264
    By:
    • Payne, Felicity;
    • Colnaghi, Rita;
    • Rocha, Nuno;
    • Seth, Asha;
    • Harris, Julie;
    • Carpenter, Gillian;
    • Bottomley, William E.;
    • Wheeler, Eleanor;
    • Wong, Stephen;
    • Saudek, Vladimir;
    • Savage, David;
    • O'Rahilly, Stephen;
    • Carel, Jean-Claude;
    • Barroso, Inês;
    • O'Driscoll, Mark;
    • Semple, Robert
    Publication type:
    Article
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    Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC.

    Published in:
    EMBO Molecular Medicine, 2009, v. 1, n. 5, p. 280, doi. 10.1002/emmm.200900037
    By:
    • Rubio-Cabezas, Oscar;
    • Puri, Vishwajeet;
    • Murano, Incoronata;
    • Saudek, Vladimir;
    • Semple, Robert K.;
    • Dash, Satya;
    • Hyden, Caroline S. S.;
    • Bottomley, William;
    • Vigouroux, Corinne;
    • Magré, Jocelyne;
    • Raymond-Barker, Philippa;
    • Murgatroyd, Peter R.;
    • Chawla, Anil;
    • Skepper, Jeremy N.;
    • Chatterjee, V. Krishna;
    • Suliman, Sara;
    • Patch, Ann-Marie;
    • Agarwal, Anil K.;
    • Garg, Abhimanyu;
    • Barroso, Inês
    Publication type:
    Article
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    Whole genome–amplified DNA: insights and imputation.

    Published in:
    2008
    By:
    • Teo, Yik Y.;
    • Inouye, Michael;
    • Small, Kerrin S.;
    • Fry, Andrew E.;
    • Potter, Simon C.;
    • Dunstan, Sarah J.;
    • Seielstad, Mark;
    • Barroso, Inês;
    • Wareham, Nicholas J.;
    • Rockett, Kirk A.;
    • Kwiatkowski, Dominic P.;
    • Deloukas, Panos
    Publication type:
    Letter
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    Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity.

    Published in:
    Diabetes, 2014, v. 63, n. 12, p. 4378, doi. 10.2337/db14-0319
    By:
    • Scott, Robert A.;
    • Fall, Tove;
    • Pasko, Dorota;
    • Barker, Adam;
    • Sharp, Stephen J.;
    • Arriola, Larraitz;
    • Balkau, Beverley;
    • Barricarte, Aurelio;
    • Barroso, Inês;
    • Boeing, Heiner;
    • Clavel-Chapelon, Françoise;
    • Crowe, Francesca L.;
    • Dekker, Jacqueline M.;
    • Fagherazzi, Guy;
    • Ferrannini, Ele;
    • Forouhi, Nita G.;
    • Franks, Paul W.;
    • Gavrila, Diana;
    • Giedraitis, Vilmantas;
    • Grioni, Sara
    Publication type:
    Article
    47

    Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity.

    Published in:
    Diabetes, 2014, v. 63, n. 6, p. 2158, doi. 10.2337/db13-0949
    By:
    • Dimas, Antigone S.;
    • Lagou, Vasiliki;
    • Barker, Adam;
    • Knowles, Joshua W.;
    • Mägi, Reedik;
    • Hivert, Marie-France;
    • Benazzo, Andrea;
    • Rybin, Denis;
    • Jackson, Anne U.;
    • Stringham, Heather M.;
    • Ci Song;
    • Fischer-Rosinsky, Antje;
    • Boesgaard, Trine Welløv;
    • Grarup, Niels;
    • Abbasi, Fahim A.;
    • Assimes, Themistocles L.;
    • Ke Hao;
    • Xia Yang;
    • Lecoeur, Cécile;
    • Barroso, Inês
    Publication type:
    Article
    48

    Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants.

    Published in:
    Diabetes, 2008, v. 57, n. 11, p. 3161, doi. 10.2337/db08-0719
    By:
    • Barroso, Inês;
    • Luan, Jian'an;
    • Wheeler, Eleanor;
    • Whittaker, Pamela;
    • Wasson, Jon;
    • Zeggini, Eleftheria;
    • Weedon, Michael N.;
    • Hunt, Sarah;
    • Venkatesh, Ranganath;
    • Frayling, Timothy M.;
    • Delgado, Marcos;
    • Neuman, Rosalind J.;
    • Zhao, Jinghua;
    • Sherva, Richard;
    • Glaser, Benjamin;
    • Walker, Mark;
    • Hitman, Graham;
    • McCarthy, Mark I.;
    • Hattersley, Andrew T.;
    • Permutt, M. Alan
    Publication type:
    Article
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