Works by Barroso, Inês

Results: 67

Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance.
Published in:
2005
By:
- Franks, Paul W.;
- Luan, Jian'an;
- Barroso, Inês;
- Brage, Søren;
- Sanchez, Jose Luis Gonzalez;
- Ekelund, Ulf;
- Ríos, Manuel Serrano;
- Schafer, Alan J.;
- O'Rahilly, Stephen;
- Wareham, Nicholas J.;
- Barroso, Inês;
- Brage, Søren;
- Gonzalez Sanchez, Jose Luis;
- Ríos, Manuel Serrano
Publication type:
journal article
Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies.
Published in:
2011
By:
- Pfister, Roman;
- Sharp, Stephen;
- Luben, Robert;
- Welsh, Paul;
- Barroso, Inês;
- Salomaa, Veikko;
- Meirhaeghe, Aline;
- Khaw, Kay-Tee;
- Sattar, Naveed;
- Langenberg, Claudia;
- Wareham, Nicholas J.;
- Barroso, Inês
Publication type:
journal article
Mendelian Randomization Analysis of Hemoglobin A<sub>1c</sub> as a Risk Factor for Coronary Artery Disease.
Published in:
2019
By:
- Leong, Aaron;
- Ji Chen;
- Wheeler, Eleanor;
- Hivert, Marie-France;
- Ching-Ti Liu;
- Merino, Jordi;
- Dupuis, Josée;
- Tai, E. Shyong;
- Rotter, Jerome I.;
- Florez, Jose C.;
- Barroso, Inês;
- Meigs, James B.;
- Chen, Ji;
- Liu, Ching-Ti
Publication type:
journal article
Whole genome–amplified DNA: insights and imputation.
Published in:
2008
By:
- Teo, Yik Y.;
- Inouye, Michael;
- Small, Kerrin S.;
- Fry, Andrew E.;
- Potter, Simon C.;
- Dunstan, Sarah J.;
- Seielstad, Mark;
- Barroso, Inês;
- Wareham, Nicholas J.;
- Rockett, Kirk A.;
- Kwiatkowski, Dominic P.;
- Deloukas, Panos
Publication type:
Letter
Genetic architecture of human thinness compared to severe obesity.
Published in:
PLoS Genetics, 2019, v. 15, n. 1, p. 1, doi. 10.1371/journal.pgen.1007603
By:
- Riveros-McKay, Fernando;
- Mistry, Vanisha;
- Bounds, Rebecca;
- Hendricks, Audrey;
- Keogh, Julia M.;
- Thomas, Hannah;
- Henning, Elana;
- Corbin, Laura J.;
- null, null;
- O’Rahilly, Stephen;
- Zeggini, Eleftheria;
- Wheeler, Eleanor;
- Barroso, Inês;
- Farooqi, I. Sadaf
Publication type:
Article
ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls.
Published in:
PLoS Genetics, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.pgen.1007591
By:
- Hendricks, Audrey E.;
- Billups, Stephen C.;
- Pike, Hamish N. C.;
- Farooqi, I. Sadaf;
- Zeggini, Eleftheria;
- Santorico, Stephanie A.;
- Barroso, Inês;
- Dupuis, Josée
Publication type:
Article
Habitual Energy Expenditure Modifies the Association Between NOS3 Gene Polymorphisms and Blood Pressure.
Published in:
American Journal of Hypertension, 2008, v. 21, n. 3, p. 297, doi. 10.1038/ajh.2007.69
By:
- Vimaleswaran, Karani S.;
- Franks, Paul W.;
- Barroso, Inês;
- Brage, Soren;
- Ekelund, Ulf;
- Wareham, Nicholas J.;
- Loos, Ruth J. F.
Publication type:
Article
Lactobacillus plantarum in Dual-Species Biofilms With Listeria monocytogenes Enhanced the Anti- Listeria Activity of a Commercial Disinfectant Based on Hydrogen Peroxide and Peracetic Acid.
Published in:
Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.631627
By:
- Bonneville, Lourenço;
- Maia, Vera;
- Barroso, Inês;
- Martínez-Suárez, Joaquín V.;
- Brito, Luisa
Publication type:
Article
Genomics: ENCODE explained.
Published in:
Nature, 2012, v. 489, n. 7414, p. 52, doi. 10.1038/489052a
By:
- Ecker, Joseph R.;
- Bickmore, Wendy A.;
- Barroso, Inês;
- Pritchard, Jonathan K.;
- Gilad, Yoav;
- Segal, Eran
Publication type:
Article
Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04788-0
By:
- Mason, Jonathan H.;
- Luo, Lu;
- Reinwald, Yvonne;
- Taffetani, Matteo;
- Hallas-Potts, Amelia;
- Herrington, C. Simon;
- Srsen, Vlastimil;
- Lin, Chih-Jen;
- Barroso, Inês A.;
- Zhang, Zhihua;
- Zhang, Zhibing;
- Ghag, Anita K.;
- Yang, Ying;
- Waters, Sarah;
- El Haj, Alicia J.;
- Bagnaninchi, Pierre O.
Publication type:
Article
Making sense of big data in health research: Towards an EU action plan.
Published in:
Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-016-0323-y
By:
- Auffray, Charles;
- Balling, Rudi;
- Barroso, Inês;
- Bencze, László;
- Benson, Mikael;
- Bergeron, Jay;
- Bernal-Delgado, Enrique;
- Blomberg, Niklas;
- Bock, Christoph;
- Conesa, Ana;
- Del Signore, Susanna;
- Delogne, Christophe;
- Devilee, Peter;
- Di Meglio, Alberto;
- Eijkemans, Marinus;
- Flicek, Paul;
- Graf, Norbert;
- Grimm, Vera;
- Guchelaar, Henk-Jan;
- Guo, Yi-Ke
Publication type:
Article
Genome-Wide Sequence Analysis of Kaposi Sarcoma-Associated Herpesvirus Shows Diversification Driven by Recombination.
Published in:
2018
By:
- Sallah, Neneh;
- Palser, Anne L;
- Watson, Simon J;
- Labo, Nazzarena;
- Asiki, Gershim;
- Marshall, Vickie;
- Newton, Robert;
- Whitby, Denise;
- Kellam, Paul;
- Barroso, Inês
Publication type:
journal article
Hypoinsulinaemic, hypoketotic hypoglycaemia due to mosaic genetic activation of PI3-kinase.
Published in:
European Journal of Endocrinology, 2017, v. 177, n. 2, p. 175, doi. 10.1530/EJE-17-0132
By:
- Leiter, Sarah M.;
- Parker, Victoria E. R.;
- Welters, Alena;
- Knox, Rachel;
- Rocha, Nuno;
- Clark, Graeme;
- Payne, Felicity;
- Lotta, Luca;
- Harris, Julie;
- Guerrero-Fernández, Julio;
- González-Casado, Isabel;
- García-Miñaur, Sixto;
- Gordo, Gema;
- Wareham, Nick;
- Martínez-Glez, Víctor;
- Allison, Michael;
- O’Rahilly, Stephen;
- Barroso, Inês;
- Meissner, Thomas;
- Davies, Susan
Publication type:
Article
Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants.
Published in:
Diabetes, 2008, v. 57, n. 11, p. 3161, doi. 10.2337/db08-0719
By:
- Barroso, Inês;
- Luan, Jian'an;
- Wheeler, Eleanor;
- Whittaker, Pamela;
- Wasson, Jon;
- Zeggini, Eleftheria;
- Weedon, Michael N.;
- Hunt, Sarah;
- Venkatesh, Ranganath;
- Frayling, Timothy M.;
- Delgado, Marcos;
- Neuman, Rosalind J.;
- Zhao, Jinghua;
- Sherva, Richard;
- Glaser, Benjamin;
- Walker, Mark;
- Hitman, Graham;
- McCarthy, Mark I.;
- Hattersley, Andrew T.;
- Permutt, M. Alan
Publication type:
Article
Evaluating the Role of LPIN1 Variation in Insulin Resistance, Body Weight, and Human Lipodystrophy in U.K. Populations.
Published in:
Diabetes, 2008, v. 57, n. 9, p. 2527, doi. 10.2337/db08-0422
By:
- Fawcett, Katherine A.;
- Grimsey, Neil;
- Loos, Ruth J. F.;
- Wheeler, Eleanor;
- Daly, Allan;
- Soos, Maria;
- Semple, Robert;
- Syddall, Holly;
- Cooper, Cyrus;
- Siniossoglou, Symeon;
- O'Rahilly, Stephen;
- Wareham, Nicholas J.;
- Barroso, Inês
Publication type:
Article
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.
Published in:
2007
By:
- Loos RJ;
- Franks PW;
- Francis RW;
- Barroso I;
- Gribble FM;
- Savage DB;
- Ong KK;
- O'Rahilly S;
- Wareham NJ;
- Loos, Ruth J F;
- Franks, Paul W;
- Francis, Richard W;
- Barroso, Inês;
- Gribble, Fiona M;
- Savage, David B;
- Ong, Ken K;
- O'Rahilly, Stephen;
- Wareham, Nicholas J
Publication type:
journal article
TCF7L2 Polymorphisms Modulate Proinsulin Levels and β-Cell Function in a British Europid Population.
Published in:
Diabetes, 2007, v. 56, n. 7, p. 1943, doi. 10.2337/db07-0055
By:
- Loos, Ruth J.;
- Franks, Paul W.;
- Francis, Richard W.;
- Barroso, Inês;
- Gribble, Fiona M.;
- Savage, David B.;
- Ong, Ken K.;
- O'Rahilly, Stephen;
- Wareham, Nicholas J.
Publication type:
Article
Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.
Published in:
2007
By:
- Mesa JL;
- Loos RJ;
- Franks PW;
- Ong KK;
- Luan J;
- O'rahilly S;
- Wareham NJ;
- Barroso I;
- Mesa, José L;
- Loos, Ruth J F;
- Franks, Paul W;
- Ong, Ken K;
- Luan, Jian'an;
- O'Rahilly, Stephen;
- Wareham, Nicholas J;
- Barroso, Inês
Publication type:
journal article
Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.
Published in:
2007
By:
- Tan K;
- Kimber WA;
- Luan J;
- Soos MA;
- Semple RK;
- Wareham NJ;
- O'rahilly S;
- Barroso I;
- Tan, Karen;
- Kimber, Wendy A;
- Luan, Jian'an;
- Soos, Maria A;
- Semple, Robert K;
- Wareham, Nicholas J;
- O'Rahilly, Stephen;
- Barroso, Inês
Publication type:
journal article
Lamin A/C Polymorphisms, Type 2 Diabetes, and the Metabolic Syndrome.
Published in:
Diabetes, 2007, v. 56, n. 3, p. 884, doi. 10.2337/db06-1055
By:
- Mesa, José L.;
- Loos, Ruth J. F.;
- Franks, Paul W.;
- Ong, Ken K.;
- Luan, Jian'an;
- O'Rahilly, Stephen;
- Wareham, Nicholas J.;
- Barroso, Inês
Publication type:
Article
Analysis of Genetic Variation in Akt2/PKB-β in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes.
Published in:
Diabetes, 2007, v. 56, n. 3, p. 714, doi. 10.2337/db06-0921
By:
- Tan, Karen;
- Kimber, Wendy A.;
- Luan, Jian'an;
- Soos, Maria A.;
- Semple, Robert K.;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen;
- Barroso, Inês
Publication type:
Article
Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes.
Published in:
2004
By:
- Laudes, Matthias;
- Barroso, Inˆes;
- Luan, Jian'an;
- Soos, Maria A.;
- Yeo, Giles;
- Meirhaeghe, Aline;
- Logie, Lisa;
- Vidal-Puig, Antonio;
- Schafer, Alan J.;
- Wareham, Nick J.;
- O'Rahilly, Stephen;
- Barroso, Inês
Publication type:
journal article
A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits.
Published in:
Genetic Epidemiology, 2015, v. 39, n. 8, p. 624, doi. 10.1002/gepi.21919
By:
- Asimit, Jennifer L.;
- Panoutsopoulou, Kalliope;
- Wheeler, Eleanor;
- Berndt, Sonja I.;
- Cordell, Heather J.;
- Morris, Andrew P.;
- Zeggini, Eleftheria;
- Barroso, Inês
Publication type:
Article
Correction: Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action.
Published in:
2003
By:
- Barroso, Inês;
- Luan, Jian'an;
- Middelberg, Rita P. S;
- Harding, Anne-Helen;
- Jakes, Rupert W;
- Clayton, David;
- Schafer, Alan J;
- O'Rahilly, Stephen;
- Wareham, Nicholas J
Publication type:
Correction Notice
Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action.
Published in:
PLoS Biology, 2003, v. 1, n. 10, p. 1, doi. 10.1371/journal.pbio.0000020
By:
- Barroso, Inês;
- Luan, Jian'an;
- Middelberg, Rita P. S;
- Harding, Anne-Helen;
- Franks, Paul W;
- Jakes, Rupert W;
- Clayton, David;
- Schafer, Alan J;
- O'Rahilly, Stephen;
- Wareham, Nicholas J
Publication type:
Article
Photocurable GelMA Adhesives for Corneal Perforations.
Published in:
Bioengineering (Basel), 2022, v. 9, n. 2, p. 53, doi. 10.3390/bioengineering9020053
By:
- Barroso, Inês A.;
- Man, Kenny;
- Robinson, Thomas E.;
- Cox, Sophie C.;
- Ghag, Anita K.
Publication type:
Article
Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.
Published in:
2022
By:
- Murphy, Neil;
- Song, Mingyang;
- Papadimitriou, Nikos;
- Carreras-Torres, Robert;
- Langenberg, Claudia;
- Martin, Richard M;
- Tsilidis, Konstantinos K;
- Barroso, Inês;
- Chen, Ji;
- Frayling, Timothy M;
- Bull, Caroline J;
- Vincent, Emma E;
- Cotterchio, Michelle;
- Gruber, Stephen B;
- Pai, Rish K;
- Newcomb, Polly A;
- Perez-Cornago, Aurora;
- Duijnhoven, Franzel J B van;
- Guelpen, Bethany Van;
- Vodicka, Pavel
Publication type:
journal article
Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04436-9
By:
- Kuchenbaecker, Karoline;
- Gilly, Arthur;
- Suveges, Daniel;
- Southam, Lorraine;
- Giannakopoulou, Olga;
- Kilian, Britt;
- Tsafantakis, Emmanouil;
- Karaleftheri, Maria;
- Farmaki, Aliki-Eleni;
- Gurdasani, Deepti;
- Kundu, Kousik;
- Sandhu, Manjinder S.;
- Danesh, John;
- Butterworth, Adam;
- Barroso, Inês;
- Dedoussis, George;
- Zeggini, Eleftheria
Publication type:
Article
Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07730-9
By:
- Gilly, Arthur;
- Suveges, Daniel;
- Kuchenbaecker, Karoline;
- Pollard, Martin;
- Southam, Lorraine;
- Hatzikotoulas, Konstantinos;
- Farmaki, Aliki-Eleni;
- Bjornland, Thea;
- Waples, Ryan;
- Appel, Emil V. R.;
- Casalone, Elisabetta;
- Melloni, Giorgio;
- Kilian, Britt;
- Rayner, Nigel W.;
- Ntalla, Ioanna;
- Kundu, Kousik;
- Walter, Klaudia;
- Danesh, John;
- Butterworth, Adam;
- Barroso, Inês
Publication type:
Article
Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07070-8
By:
- Gilly, Arthur;
- Suveges, Daniel;
- Kuchenbaecker, Karoline;
- Pollard, Martin;
- Southam, Lorraine;
- Hatzikotoulas, Konstantinos;
- Farmaki, Aliki-Eleni;
- Bjornland, Thea;
- Waples, Ryan;
- Appel, Emil V. R.;
- Casalone, Elisabetta;
- Melloni, Giorgio;
- Kilian, Britt;
- Rayner, Nigel W.;
- Ntalla, Ioanna;
- Kundu, Kousik;
- Walter, Klaudia;
- Danesh, John;
- Butterworth, Adam;
- Barroso, Inês
Publication type:
Article
Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study.
Published in:
PLoS Genetics, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.pgen.1004388
By:
- Varga, Tibor V.;
- Sonestedt, Emily;
- Shungin, Dmitry;
- Koivula, Robert W.;
- Hallmans, Göran;
- Escher, Stefan A.;
- Barroso, Inês;
- Nilsson, Peter;
- Melander, Olle;
- Orho-Melander, Marju;
- Renström, Frida;
- Franks, Paul W.
Publication type:
Article
Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations.
Published in:
PLoS Genetics, 2010, v. 6, n. 4, p. 1, doi. 10.1371/journal.pgen.1000895
By:
- Nica, Alexandra C.;
- Montgomery, Stephen B.;
- Dimas, Antigone S.;
- Stranger, Barbara E.;
- Beazley, Claude;
- Barroso, Inês;
- Dermitzakis, Emmanouil T.
Publication type:
Article
Hyperglycaemia is a causal risk factor for upper limb pathologies.
Published in:
International Journal of Epidemiology, 2024, v. 53, n. 1, p. 1, doi. 10.1093/ije/dyad187
By:
- Green, Harry D;
- Burden, Ella;
- Chen, Ji;
- Evans, Jonathan;
- Patel, Kashyap;
- Wood, Andrew R;
- Beaumont, Robin N;
- Tyrrell, Jessica;
- Frayling, Timothy M;
- Hattersley, Andrew T;
- Oram, Richard A;
- Bowden, Jack;
- Barroso, Inês;
- Smith, Christopher;
- Weedon, Michael N
Publication type:
Article
Photocurable antimicrobial silk‐based hydrogels for corneal repair.
Published in:
Journal of Biomedical Materials Research, Part A, 2022, v. 110, n. 7, p. 1401, doi. 10.1002/jbm.a.37381
By:
- Barroso, Inês A.;
- Man, Kenny;
- Hall, Thomas J.;
- Robinson, Thomas E.;
- Louth, Sophie E. T.;
- Cox, Sophie C.;
- Ghag, Anita K.
Publication type:
Article
Controlled Release of Epigenetically-Enhanced Extracellular Vesicles from a GelMA/Nanoclay Composite Hydrogel to Promote Bone Repair.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 832, doi. 10.3390/ijms23020832
By:
- Man, Kenny;
- Barroso, Inês A.;
- Brunet, Mathieu Y.;
- Peacock, Ben;
- Federici, Angelica S.;
- Hoey, David A.;
- Cox, Sophie C.
Publication type:
Article
Leveraging information between multiple population groups and traits improves fine-mapping resolution.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43159-5
By:
- Zhou, Feng;
- Soremekun, Opeyemi;
- Chikowore, Tinashe;
- Fatumo, Segun;
- Barroso, Inês;
- Morris, Andrew P.;
- Asimit, Jennifer L.
Publication type:
Article
Complex disease: Pleiotropic gene effects in obesity and type 2 diabetes.
Published in:
European Journal of Human Genetics, 2005, v. 13, n. 12, p. 1243, doi. 10.1038/sj.ejhg.5201514
By:
- Barroso, Inês
Publication type:
Article
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Published in:
Nature Genetics, 2015, v. 47, n. 11, p. 1282, doi. 10.1038/ng.3405
By:
- Loh, Marie;
- Zhang, Weihua;
- Saleheen, Danish;
- Wahl, Simone;
- Tan, Sian-Tsung;
- Scott, William R;
- Afzal, Uzma;
- Ahluwalia, Tarunveer S;
- Esko, Tõnu;
- Harris, Sarah E;
- Hartiala, Jaana;
- Khor, Chiea-Chuen;
- Stewart, Alexandre F R;
- Wu, Jer-Yuarn;
- Zhang, Yi;
- Lyytikäinen, Leo-Pekka;
- Postmus, Iris;
- Raitakari, Olli T;
- Traglia, Michela;
- Barroso, Inês
Publication type:
Article
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
Published in:
Nature Genetics, 2013, v. 45, n. 5, p. 513, doi. 10.1038/ng.2607
By:
- Wheeler, Eleanor;
- Huang, Ni;
- Bochukova, Elena G;
- Keogh, Julia M;
- Lindsay, Sarah;
- Garg, Sumedha;
- Henning, Elana;
- Blackburn, Hannah;
- Loos, Ruth J F;
- Wareham, Nick J;
- O'Rahilly, Stephen;
- Hurles, Matthew E;
- Barroso, Inês;
- Farooqi, I Sadaf
Publication type:
Article
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
Published in:
Nature Genetics, 2010, v. 42, n. 5, p. 436, doi. 10.1038/ng.572
By:
- Liu, Jason Z.;
- Tozzi, Federica;
- Waterworth, Dawn M.;
- Pillai, Sreekumar G.;
- Muglia, Pierandrea;
- Middleton, Lefkos;
- Berrettini, Wade;
- Knouff, Christopher W.;
- Xin Yuan;
- Waeber, Gérard;
- Vollenweider, Peter;
- Preisig, Martin;
- Wareham, Nicholas J.;
- Jing Hua Zhao;
- Loos, Ruth J F.;
- Barroso, Inês;
- Kay-Tee Khaw;
- Grundy, Scott;
- Barter, Philip;
- Mahley, Robert
Publication type:
Article
Genome-wide association study identifies five loci associated with lung function.
Published in:
Nature Genetics, 2010, v. 42, n. 1, p. 36, doi. 10.1038/ng.501
By:
- Repapi, Emmanouela;
- Sayers, Ian;
- Wain, Louise V.;
- Burton, Paul R.;
- Johnson, Toby;
- Obeidat, Ma'en;
- Jing Hua Zhao;
- Ramasamy, Adaikalavan;
- Guangju Zhai;
- Vitart, Veronique;
- Huffman, Jennifer E.;
- Igl, Wilmar;
- Albrecht, Eva;
- Deloukas, Panos;
- Henderson, John;
- Granell, Raquel;
- McArdle, Wendy L.;
- Rudnicka, Alicja R.;
- Barroso, Inês;
- Loos, Ruth J. F.
Publication type:
Article
Digenic inheritance of severe insulin resistance in a human pedigree.
Published in:
Nature Genetics, 2002, v. 31, n. 4, p. 379, doi. 10.1038/ng926
By:
- Savage, David B.;
- Agostini, Maura;
- Barroso, Inês;
- Gurnell, Mark;
- Luan, Jian'an;
- Meirhaeghe, Aline;
- Harding, Anne-Helen;
- Ihrke, Gudrun;
- Rajanayagam, Odelia;
- Soos, Maria A.;
- George, Stella;
- Berger, Dirk;
- Thomas, E. Louise;
- Bell, Jimmy D.;
- Meeran, Karim;
- Ross, Richard J.;
- Vidal-Puig, Antonio;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen;
- Chatterjee, V. Krishna K.
Publication type:
Article
The influence of rare variants in circulating metabolic biomarkers.
Published in:
PLoS Genetics, 2020, v. 16, n. 3, p. 1, doi. 10.1371/journal.pgen.1008605
By:
- Riveros-Mckay, Fernando;
- Oliver-Williams, Clare;
- Karthikeyan, Savita;
- Walter, Klaudia;
- Kundu, Kousik;
- Ouwehand, Willem H.;
- Roberts, David;
- Di Angelantonio, Emanuele;
- Soranzo, Nicole;
- Danesh, John;
- Wheeler, Eleanor;
- Zeggini, Eleftheria;
- Butterworth, Adam S.;
- Barroso, Inês
Publication type:
Article
Genetic aetiology of glycaemic traits: approaches and insights.
Published in:
Human Molecular Genetics, 2017, v. 26, p. R172, doi. 10.1093/hmg/ddx293
By:
- Wheeler, Eleanor;
- Marenne, Gaëlle;
- Barroso, Inês
Publication type:
Article
Homozygous loss-of-function variants in European cosmopolitan and isolate populations.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 19, p. 5464, doi. 10.1093/hmg/ddv272
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- Kaiser, Vera B.;
- Svinti, Victoria;
- Prendergast, James G.;
- You-Ying Chau;
- Campbell, Archie;
- Patarcic, Inga;
- Barroso, Inês;
- Joshi, Peter K.;
- Hastie, Nicholas D.;
- Miljkovic, Ana;
- Taylor, Martin S.;
- Scotland, Generation;
- Enroth, Stefan;
- Memari, Yasin;
- Kolb-Kokocinski, Anja;
- Wright, Alan F.;
- Gyllensten, Ulf;
- Durbin, Richard;
- Rudan, Igor;
- Campbell, Harry
Publication type:
Article
Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations.
Published in:
American Journal of Epidemiology, 2009, v. 170, n. 5, p. 537, doi. 10.1093/aje/kwp145
By:
- Salanti, Georgia;
- Southam, Lorraine;
- Altshuler, David;
- Ardlie, Kristin;
- Barroso, Inês;
- Boehnke, Michael;
- Cornelis, Marilyn C.;
- Frayling, Timothy M.;
- Grallert, Harald;
- Grarup, Niels;
- Groop, Leif;
- Hansen, Torben;
- Hattersley, Andrew T.;
- Hu, Frank B.;
- Hveem, Kristian;
- Illig, Thomas;
- Kuusisto, Johanna;
- Laakso, Markku;
- Langenberg, Claudia;
- Lyssenko, Valeriya
Publication type:
Article
Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 4, p. 1065, doi. 10.1210/clinem/dgab877
By:
- Koprulu, Mine;
- Zhao, Yajie;
- Wheeler, Eleanor;
- Dong, Liang;
- Rocha, Nuno;
- Li, Chen;
- Griffin, John D.;
- Patel, Satish;
- de Streek, Marcel Van;
- Glastonbury, Craig A.;
- Stewart, Isobel D.;
- Day, Felix R.;
- Luan, Jian’an;
- Bowker, Nicholas;
- Wittemans, Laura B. L.;
- Kerrison, Nicola D.;
- Cai, Lina;
- Lucarelli, Debora M. E.;
- Barroso, Inês;
- McCarthy, Mark I.
Publication type:
Article
Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4028, doi. 10.1172/JCI73264
By:
- Payne, Felicity;
- Colnaghi, Rita;
- Rocha, Nuno;
- Seth, Asha;
- Harris, Julie;
- Carpenter, Gillian;
- Bottomley, William E.;
- Wheeler, Eleanor;
- Wong, Stephen;
- Saudek, Vladimir;
- Savage, David;
- O'Rahilly, Stephen;
- Carel, Jean-Claude;
- Barroso, Inês;
- O'Driscoll, Mark;
- Semple, Robert
Publication type:
Article
Human SH2B1 mutations are associated with maladaptive behaviors and obesity.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 12, p. 4732, doi. 10.1172/JCI62696
By:
- Doche, Michael E.;
- Bochukova, Elena G.;
- Hsiao-Wen Su;
- Pearce, Laura R.;
- Keogh, Julia M.;
- Henning, Elana;
- Cline, Joel M.;
- Dale, Anne;
- Cheetham, Tim;
- Barroso, Inês;
- Argetsinger, Lawrence S.;
- O'Rahilly, Stephen;
- Liangyou Rui;
- Christin Carter-Su;
- Farooqi, I. Sadaf
Publication type:
Article
Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.23813.001
By:
- Rocha, Nuno;
- Bulger, David A.;
- Frontini, Andrea;
- Titheradge, Hannah;
- Gribsholt, Sigrid Bjerge;
- Knox, Rachel;
- Page, Matthew;
- Harris, Julie;
- Payne, Felicity;
- Adams, Claire;
- Sleigh, Alison;
- Crawford, John;
- Gjesing, Anette Prior;
- Bork-Jensen, Jette;
- Pedersen, Oluf;
- Barroso, Inês;
- Hansen, Torben;
- Cox, Helen;
- Reilly, Mary;
- Rossor, Alex
Publication type:
Article