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Consideration of the Root Causes in Candidate Attrition During Oncology Drug Development.
- Published in:
- Clinical Pharmacology in Drug Development, 2024, v. 13, n. 9, p. 952, doi. 10.1002/cpdd.1464
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- Publication type:
- Article
Clinical importance of the drug interaction between statins and CYP3A4 inhibitors: a retrospective cohort study in The Health Improvement Network.
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- Pharmacoepidemiology & Drug Safety, 2012, v. 21, n. 5, p. 494, doi. 10.1002/pds.3199
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- Publication type:
- Article
Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors.
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- Pharmacoepidemiology & Drug Safety, 2009, v. 18, n. 4, p. 301, doi. 10.1002/pds.1711
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- Publication type:
- Article
Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men.
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- Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 4, p. 377, doi. 10.1038/clpt.1994.152
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- Publication type:
- Article
Diagnosing malabsorption with systemic lipid profiling: pharmacokinetics of pentadecanoic acid and triheptadecanoic acid following oral administration in healthy subjects and subjects with cystic fibrosis.
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- International Journal of Clinical Pharmacology & Therapeutics, 2013, v. 51, n. 4, p. 263, doi. 10.5414/CP201793
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- Publication type:
- Article
Adjuvant therapies for HIV-associated neurocognitive disorders.
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- Annals of Clinical & Translational Neurology, 2014, v. 1, n. 11, p. 938, doi. 10.1002/acn3.131
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- Article
Digital Research Environment(DRE)-enabled Artificial Intelligence (AI) to facilitate early stage drug development.
- Published in:
- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1115356
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- Publication type:
- Article
Melatonin pharmacokinetics following two different oral surge-sustained release doses in older adults.
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- Journal of Pineal Research, 2012, v. 52, n. 4, p. 437, doi. 10.1111/j.1600-079X.2011.00958.x
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- Publication type:
- Article
Role of Disease Progression Models in Drug Development.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 8, p. 1803, doi. 10.1007/s11095-022-03257-3
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- Publication type:
- Article
Characterization of Intestinal and Hepatic CYP3A-Mediated Metabolism of Midazolam in Children Using a Physiological Population Pharmacokinetic Modelling Approach.
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- Pharmaceutical Research, 2018, v. 35, n. 9, p. 1, doi. 10.1007/s11095-018-2458-6
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- Publication type:
- Article
Prescribing habits and caregiver satisfaction with resources for dosing children: Rationale for more informative dosing guidance.
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- BMC Pediatrics, 2011, v. 11, n. 1, p. 25, doi. 10.1186/1471-2431-11-25
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- Publication type:
- Article
Artificial Intelligence Opportunities to Guide Precision Dosing Strategies.
- Published in:
- Journal of Pediatric Pharmacology & Therapeutics, 2024, v. 29, n. 4, p. 434, doi. 10.5863/1551-6776-29.4.434
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- Publication type:
- Article
The Precompetitive Space for Drug or Vaccine Development: What Does It Look Like Now and What Could It Look Like in the Future?
- Published in:
- Journal of Pediatric Pharmacology & Therapeutics, 2023, v. 28, n. 5, p. 465, doi. 10.5863/1551-6776-28.5.465
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- Publication type:
- Article
Asking More of Our EHR Systems to Improve Outcomes for Pediatric Patients.
- Published in:
- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00253
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- Publication type:
- Article
Abundant anti-apoptotic BCL-2 is a molecular target in leukaemias with t(4;11) translocation.
- Published in:
- British Journal of Haematology, 2008, v. 141, n. 6, p. 827, doi. 10.1111/j.1365-2141.2008.07100.x
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- Publication type:
- Article
Population Pharmacokinetic Model of Sublingual Buprenorphine in Neonatal Abstinence Syndrome.
- Published in:
- Pharmacotherapy, 2015, v. 35, n. 7, p. 670, doi. 10.1002/phar.1610
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- Publication type:
- Article
Disposition and exposure of the fibrinogen receptor antagonist XV459 on α<sub>IIB</sub>β<sub>3</sub> binding sites in the guinea pig.
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- Biopharmaceutics & Drug Disposition, 1999, v. 20, n. 6, p. 309, doi. 10.1002/(SICI)1099-081X(199909)20:6<309::AID-BDD190>3.0.CO;2-7
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- Publication type:
- Article
Pharmacokinetic evaluation of a selegiline pulsatile oral delivery system.
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- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 8, p. 665, doi. 10.1002/(SICI)1099-081X(199711)18:8<665::AID-BDD47>3.0.CO;2-A
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- Publication type:
- Article
Integrated pharmacokinetic and metabolic modeling of selegiline and metabolites after transdermal administration.
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- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 7, p. 567, doi. 10.1002/(SICI)1099-081X(199710)18:7<567::AID-BDD49>3.0.CO;2-7
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- Publication type:
- Article
TOXICOKINETIC EVALUATION OF A SELEGILINE TRANSDERMAL SYSTEM IN THE DOG.
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- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 2, p. 165, doi. 10.1002/(SICI)1099-081X(199703)18:2<165::AID-BDD14>3.0.CO;2-S
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- Publication type:
- Article
A Sensitive and Selective Liquid Chromatography/Tandem Mass Spectrometry Method for Quantitative Analysis of Efavirenz in Human Plasma.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0063305
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- Publication type:
- Article
A Randomized, Placebo Controlled, Double Masked Phase IB Study Evaluating the Safety and Antiviral Activity of Aprepitant, a Neurokinin-1 Receptor Antagonist in HIV-1 Infected Adults.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024180
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- Publication type:
- Article
Linear-In-Flux-Expressions Methodology: Toward a Robust Mathematical Framework for Quantitative Systems Pharmacology Simulators.
- Published in:
- Gene Regulation & Systems Biology, 2017, n. 11, p. 1, doi. 10.1177/1177625017711414
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- Publication type:
- Article
A Quantitative Systems Pharmacology Platform to Investigate the Impact of Alirocumab and Cholesterol-Lowering Therapies on Lipid Profiles and Plaque Characteristics.
- Published in:
- Gene Regulation & Systems Biology, 2017, n. 11, p. 1, doi. 10.1177/1177625017710941
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- Publication type:
- Article
Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV.
- Published in:
- 2016
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- Publication type:
- journal article
Identifying novel phenotypes of vulnerability and resistance to activity-based anorexia in adolescent female rats.
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- International Journal of Eating Disorders, 2013, v. 46, n. 7, p. 737, doi. 10.1002/eat.22149
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- Publication type:
- Article
Supporting Prospective Pregnancy Trials via Modeling and Simulation: Lessons From the Past and Recommendations for the Future.
- Published in:
- Journal of Clinical Pharmacology, 2023, v. 63, p. S51, doi. 10.1002/jcph.2284
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- Publication type:
- Article
Opportunities for Systems Biology and Quantitative Systems Pharmacology to Address Knowledge Gaps for Drug Development in Pregnancy.
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- Journal of Clinical Pharmacology, 2023, v. 63, p. S96, doi. 10.1002/jcph.2265
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- Publication type:
- Article
Natural History and Real‐World Data in Rare Diseases: Applications, Limitations, and Future Perspectives.
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- Journal of Clinical Pharmacology, 2022, v. 62, p. S38, doi. 10.1002/jcph.2134
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- Publication type:
- Article
Model‐Informed Pediatric Drug Development: Application of Pharmacometrics to Define the Right Dose for Children.
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- Journal of Clinical Pharmacology, 2021, v. 61, p. S52, doi. 10.1002/jcph.1841
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- Article
Status Toward the Implementation of Precision Dosing in Children.
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- Journal of Clinical Pharmacology, 2021, v. 61, p. S36, doi. 10.1002/jcph.1830
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- Publication type:
- Article
Perspective on Data‐Sharing Requirements for the Necessary Evolution of Drug Development.
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- Journal of Clinical Pharmacology, 2020, v. 60, n. 6, p. 688, doi. 10.1002/jcph.1607
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- Publication type:
- Article
A sensitive and selective liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of actinomycin-D and vincristine in children with cancer.
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- Journal of Mass Spectrometry, 2007, v. 42, n. 6, p. 761, doi. 10.1002/jms.1211
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- Article
Correction to: Training the next generation of pharmacometric modelers: a multisector perspective.
- Published in:
- 2024
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- Publication type:
- Correction Notice
Training the next generation of pharmacometric modelers: a multisector perspective.
- Published in:
- 2024
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- Publication type:
- Letter
The future of rare disease drug development: the rare disease cures accelerator data analytics platform (RDCA-DAP).
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 6, p. 507, doi. 10.1007/s10928-023-09859-7
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- Publication type:
- Article
Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.988974
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- Publication type:
- Article
Editorial: Insights in obstetric and pediatric pharmacology: 2021.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.995923
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- Article
Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents.
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- British Journal of Clinical Pharmacology, 2015, v. 80, n. 5, p. 1185, doi. 10.1111/bcp.12693
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- Publication type:
- Article
Paediatric models in motion: requirements for model-based decision support at the bedside.
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- British Journal of Clinical Pharmacology, 2015, v. 79, n. 1, p. 85, doi. 10.1111/bcp.12287
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- Publication type:
- Article
History and Future Perspectives on the Discipline of Quantitative Systems Pharmacology Modeling and Its Applications.
- Published in:
- Frontiers in Physiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphys.2021.637999
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- Publication type:
- Article
An AI Approach to Generating MIDD Assets Across the Drug Development Continuum.
- Published in:
- AAPS Journal, 2023, v. 25, n. 4, p. 1, doi. 10.1208/s12248-023-00838-x
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- Publication type:
- Article
A Pediatric Covariate Function for CYP3A-Mediated Midazolam Clearance Can Scale Clearance of Selected CYP3A Substrates in Children.
- Published in:
- AAPS Journal, 2019, v. 21, n. 5, p. N.PAG, doi. 10.1208/s12248-019-0351-9
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- Publication type:
- Article
Strategic Biomarkers for Drug Development in Treating Rare Diseases and Diseases in Neonates and Infants.
- Published in:
- AAPS Journal, 2013, v. 15, n. 2, p. 447, doi. 10.1208/s12248-013-9452-z
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- Publication type:
- Article
Advancing the utilization of real‐world data and real‐world evidence in clinical pharmacology and translational research—Proceedings from the ASCPT 2023 preconference workshop.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 4, p. 1, doi. 10.1111/cts.13785
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- Article
Engaging student opinions on vaccine development innovation: Experiences from a "Shark Tank" project.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 2, p. 1, doi. 10.1111/cts.13723
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- Publication type:
- Article
Dactinomycin and vincristine toxicity in the treatment of childhood cancer: A retrospective study from the Children's Oncology Group.
- Published in:
- Pediatric Blood & Cancer, 2011, v. 57, n. 2, p. 252, doi. 10.1002/pbc.22882
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- Publication type:
- Article
Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults.
- Published in:
- 2018
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- Publication type:
- journal article
Application and impact of population pharmacokinetics in the assessment of antiretroviral pharmacotherapy.
- Published in:
- 2005
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- Publication type:
- journal article
Pharmacodynamic Analysis of the Microbiological Efficacy of Telithromycin in Patients with Community-Acquired Pneumonia.
- Published in:
- Clinical Pharmacokinetics, 2005, v. 44, n. 3, p. 317, doi. 10.2165/00003088-200544030-00007
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- Publication type:
- Article