Works by Barran, Perdita

Results: 63

Conformational landscapes of rigid and flexible molecules explored with variable temperature ion mobility-mass spectrometry.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59065-x

By:

Wang, Xudong;
Norgate, Emma;
Dai, Junxiao;
Benoit, Florian;
Bristow, Tony;
England, Richard M.;
Kalapothakis, Jason M. D.;
Barran, Perdita E.

Publication type:

Article

Studying Cation Exchange in {Cr7Co} Pseudorotaxanes: Preparatory Studies for Making Hybrid Molecular Machines.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 37, p. 1, doi. 10.1002/chem.202400432

By:

Bennett, Tom S.;
Geue, Niklas;
Timco, Grigore A.;
Whitehead, George F. S.;
Vitorica‐Yrezabal, Inigo J.;
Barran, Perdita E.;
McInnes, Eric J. L.;
Winpenny, Richard E. P.

Publication type:

Article

Hexanuclear Ln6L6 Complex Formation by Using an Unsymmetric Ligand.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 71, p. 1, doi. 10.1002/chem.202302497

By:

Bell, Daniel J.;
Zhang, Tongtong;
Geue, Niklas;
Rogers, Ciarán J.;
Barran, Perdita E.;
Bowen, Alice M.;
Natrajan, Louise S.;
Riddell, Imogen A.

Publication type:

Article

Probing the Conformational Diversity of Cancer-Associated Mutations in p53 with Ion-Mobility Mass Spectrometry.

Published in:

Angewandte Chemie, 2013, v. 125, n. 16, p. 4466, doi. 10.1002/ange.201210015

By:

Jurneczko, Ewa;
Cruickshank, Faye;
Porrini, Massimiliano;
Clarke, David J.;
Campuzano, Iain D. G.;
Morris, Michael;
Nikolova, Penka V.;
Barran, Perdita E.

Publication type:

Article

Sequential, Kinetically Controlled Synthesis of Multicomponent Stereoisomeric Assemblies.

Published in:

Angewandte Chemie, 2012, v. 124, n. 17, p. 4270, doi. 10.1002/ange.201108994

By:

Chepelin, Oleg;
Ujma, Jakub;
Barran, Perdita E.;
Lusby, Paul J.

Publication type:

Article

Innentitelbild: Sequential, Kinetically Controlled Synthesis of Multicomponent Stereoisomeric Assemblies (Angew. Chem. 17/2012).

Published in:

Angewandte Chemie, 2012, v. 124, n. 17, p. 4048, doi. 10.1002/ange.201201577

By:

Chepelin, Oleg;
Ujma, Jakub;
Barran, Perdita E.;
Lusby, Paul J.

Publication type:

Article

Rücktitelbild: Active-Metal Template Synthesis of a Molecular Trefoil Knot (Angew. Chem. 51/2011).

Published in:

Angewandte Chemie, 2011, v. 123, n. 51, p. 12574, doi. 10.1002/ange.201106646

By:

Barran, Perdita E.;
Cole, Harriet L.;
Goldup, Stephen M.;
Leigh, David A.;
McGonigal, Paul R.;
Symes, Mark D.;
Wu, Jhenyi;
Zengerle, Michael

Publication type:

Article

Active-Metal Template Synthesis of a Molecular Trefoil Knot.

Published in:

Angewandte Chemie, 2011, v. 123, n. 51, p. 12488, doi. 10.1002/ange.201105012

By:

Barran, Perdita E.;
Cole, Harriet L.;
Goldup, Stephen M.;
Leigh, David A.;
McGonigal, Paul R.;
Symes, Mark D.;
Wu, Jhenyi;
Zengerle, Michael

Publication type:

Article

Proteinstrukturaufklärung in der Gasphase.

Published in:

Angewandte Chemie, 2011, v. 123, n. 14, p. 3176, doi. 10.1002/ange.201007231

By:

Barran, Perdita E.

Publication type:

Article

Characterizing Early Aggregates Formed by an Amyloidogenic Peptide by Mass Spectrometry.

Published in:

Angewandte Chemie, 2010, v. 122, n. 49, p. 9638, doi. 10.1002/ange.201003373

By:

Cole, Harriet L.;
Kalapothakis, Jason M. D.;
Bennett, Guy;
Barran, Perdita E.;
MacPhee, Cait E.

Publication type:

Article

Structure-activity relationships in β-defensin peptides.

Published in:

Biopolymers, 2008, v. 90, n. 1, p. 1, doi. 10.1002/bip.20900

By:

Taylor, Karen;
Barran, Perdita E.;
Dorin, Julia R.

Publication type:

Article

Bile salts enhance the susceptibility of the peach allergenic lipid transfer protein, Pru p 3, to in vitro gastrointestinal proteolysis.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39599-0

By:

Wang, Kai;
Gali-Moya, Judit;
Ruano-Zaragoza, Maria;
Cain, Kathleen;
D'Auria, Giovanni;
Daly, Matthew;
Barran, Perdita;
Crevel, René;
Mills, E. N. Clare

Publication type:

Article

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4.

Published in:

European Journal of Immunology, 2009, v. 39, n. 5, p. 1353, doi. 10.1002/eji.200838566

By:

Taylor, Karen;
Rolfe, Mark;
Reynolds, Natalie;
Kilanowski, Fiona;
Pathania, Uday;
Clarke, Dave;
Yang, De;
Oppenheim, Joost;
Samuel, Kay;
Howie, Sarah;
Barran, Perdita;
Macmillan, Derek;
Campopiano, Dominic;
Dorin, Julia

Publication type:

Article

Structural investigation of naturally occurring peptides by electron capture dissociation and AMBER force field modelling.

Published in:

Molecular Physics, 2005, v. 103, n. 11/12, p. 1481, doi. 10.1080/00268970500095998

By:

Polfer, Nick C.;
Haselmann, Kim F.;
Langridge-Smith, Pat R. R.;
Barran, Perdita E.

Publication type:

Article

Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug‐to‐Antibody Ratios**.

Published in:

ChemSusChem, 2022, v. 15, n. 9, p. 1, doi. 10.1002/cssc.202102592

By:

Angelastro, Antonio;
Barkhanskiy, Alexey;
Mattey, Ashley P.;
Pallister, Edward G.;
Spiess, Reynard;
Goundry, William;
Barran, Perdita;
Flitsch, Sabine L.

Publication type:

Article

GnRH-Mediated DAN Production Regulates the Transcription of the GnRH Receptor in Gonadotrope Cells.

Published in:

NeuroMolecular Medicine, 2007, v. 9, n. 3, p. 230, doi. 10.1007/s12017-007-8004-z

By:

López de Maturana, Rakel;
Martin, Bronwen;
Millar, Robert;
Brown, Pamela;
Davidson, Lindsay;
Pawson, Adam;
Nicol, Moira;
Mason, J.;
Barran, Perdita;
Naor, Zvi;
Maudsley, Stuart

Publication type:

Article

Nanohoops Favour Light‐Induced Energy Transfer over Charge Separation in Porphyrin/[10]CPP/Fullerene Rotaxanes.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 1, p. 1, doi. 10.1002/anie.202413404

By:

Schwer, Fabian;
Zank, Simon;
Freiberger, Markus;
Steudel, Fabian M.;
Geue, Niklas;
Ye, Lei;
Barran, Perdita E.;
Drewello, Thomas;
Guldi, Dirk M.;
von Delius, Max

Publication type:

Article

Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage**.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 25, p. 1, doi. 10.1002/anie.202115047

By:

Norgate, Emma L.;
Upton, Rosie;
Hansen, Kjetil;
Bellina, Bruno;
Brookes, C.;
Politis, Argyris;
Barran, Perdita E.

Publication type:

Article

An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals.

Published in:

Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0076-9

By:

Carbonell, Pablo;
Jervis, Adrian J.;
Robinson, Christopher J.;
Yan, Cunyu;
Dunstan, Mark;
Swainston, Neil;
Vinaixa, Maria;
Hollywood, Katherine A.;
Currin, Andrew;
Rattray, Nicholas J. W.;
Taylor, Sandra;
Spiess, Reynard;
Sung, Rehana;
Williams, Alan R.;
Fellows, Donal;
Stanford, Natalie J.;
Mulherin, Paul;
Le Feuvre, Rosalind;
Barran, Perdita;
Goodacre, Royston

Publication type:

Article

Uncoupling conformational states from activity in an allosteric enzyme.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00224-0

By:

Pisco, João P.;
de Chiara, Cesira;
Pacholarz, Kamila J.;
Garza-Garcia, Acely;
Ogrodowicz, Roksana W.;
Walker, Philip A.;
Barran, Perdita E.;
Smerdon, Stephen J.;
de Carvalho, Luiz Pedro S.

Publication type:

Article

Molecular Insights into the Thermal Stability of mAbs with Variable-Temperature Ion-Mobility Mass Spectrometry.

Published in:

ChemBioChem, 2016, v. 17, n. 1, p. 46, doi. 10.1002/cbic.201500574

By:

Pacholarz, Kamila J.;
Peters, Shirley J.;
Garlish, Rachel A.;
Henry, Alistair J.;
Taylor, Richard J.;
Humphreys, David P.;
Barran, Perdita E.

Publication type:

Article

Synthesis of Cyclic Peptides through an Intramolecular Amide Bond Rearrangement.

Published in:

ChemBioChem, 2011, v. 12, n. 14, p. 2133, doi. 10.1002/cbic.201100364

By:

Macmillan, Derek;
De Cecco, Martin;
Reynolds, Natalie L.;
Santos, Luiz F. A.;
Barran, Perdita E.;
Dorin, Julia R.

Publication type:

Article

Design and Synthesis of Conformationally Constrained Cyclophilin Inhibitors Showing a Cyclosporin-A Phenotype in C. elegans.

Published in:

ChemBioChem, 2011, v. 12, n. 5, p. 802, doi. 10.1002/cbic.201000413

By:

Dunsmore, Colin J.;
Malone, Kirk J.;
Bailey, Kevin R.;
Wear, Martin A.;
Florance, Hannah;
Shirran, Sally;
Barran, Perdita E.;
Page, Antony P.;
Walkinshaw, Malcolm D.;
Turner, Nicholas J.

Publication type:

Article

Ion Mobility Mass Spectrometry Measures the Conformational Landscape of p27 and its Domains and how this is Modulated upon Interaction with Cdk2/cyclin A.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 10, p. 3114, doi. 10.1002/anie.201812697

By:

Beveridge, Rebecca;
Migas, Lukasz G.;
Kriwacki, Richard W.;
Barran, Perdita E.

Publication type:

Article

Initial Steps of Amyloidogenic Peptide Assembly Revealed by Cold-Ion Spectroscopy.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 1, p. 213, doi. 10.1002/anie.201710188

By:

Ujma, Jakub;
Kopysov, Vladimir;
Nagornova, Natalia S.;
Migas, Lukasz G.;
Lizio, Maria Giovanna;
Blanch, Ewan W.;
MacPhee, Cait;
Boyarkin, Oleg V.;
Barran, Perdita E.

Publication type:

Article

Dynamics of Intact Immunoglobulin G Explored by Drift-Tube Ion-Mobility Mass Spectrometry and Molecular Modeling.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 30, p. 7765, doi. 10.1002/anie.201402863

By:

Pacholarz, Kamila J.;
Porrini, Massimiliano;
Garlish, Rachel A.;
Burnley, Rebecca J.;
Taylor, Richard J.;
Henry, Alistair J.;
Barran, Perdita E.

Publication type:

Article

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes.

Published in:

Diabetologia, 2020, v. 63, n. 2, p. 313, doi. 10.1007/s00125-019-05029-y

By:

Sayers, Sophie R.;
Beavil, Rebecca L.;
Fine, Nicholas H. F.;
Huang, Guo C.;
Choudhary, Pratik;
Pacholarz, Kamila J.;
Barran, Perdita E.;
Butterworth, Sam;
Mills, Charlotte E.;
Cruickshank, J. Kennedy;
Silvestre, Marta P.;
Poppitt, Sally D.;
McGill, Anne-Thea;
Lavery, Gareth G.;
Hodson, David J.;
Caton, Paul W.

Publication type:

Article

Baseline proteomics characterisation of the emerging host biomanufacturing organism Halomonas bluephagenesis.

Published in:

Scientific Data, 2022, v. 9, n. 1, p. 1, doi. 10.1038/s41597-022-01610-0

By:

Russell, Matthew;
Currin, Andrew;
Rowe, William;
Chen, Guo-Qiang;
Barran, Perdita;
Scrutton, Nigel S.

Publication type:

Article

SYNBIOCHEM - a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals.

Published in:

Biochemical Society Transactions, 2016, v. 44, n. 3, p. 675, doi. 10.1042/BST20160009

By:

Carbonell, Pablo;
Currin, Andrew;
Dunstan, Mark;
Fellows, Donal;
Jervis, Adrian;
Rattray, Nicholas J. W.;
Robinson, Christopher J.;
Swainston, Neil;
Vinaixa, Maria;
Williams, Alan;
Cunyu Yan;
Barran, Perdita;
Breitling, Rainer;
George Guo-Qiang Chen;
Jean-Loup Faulon;
Goble, Carole;
Goodacre, Royston;
Kell, Douglas B.;
Le Feuvre, Rosalind;
Micklefield, Jason

Publication type:

Article

Intrinsic disorder in proteins: a challenge for (un)structural biology met by ion mobility-mass spectrometry.

Published in:

Biochemical Society Transactions, 2012, v. 40, n. 5, p. 1021, doi. 10.1042/BST20120125

By:

Jurneczko, Ewa;
Cruickshank, Faye;
Porrini, Massimiliano;
Nikolova, Penka;
Campuzano, Iain D. G.;
Morris, Michael;
Barran, Perdita E.

Publication type:

Article

Ion Mobility Mass Spectrometry Measures the Conformational Landscape of p27 and its Domains and how this is Modulated upon Interaction with Cdk2/cyclin A.

Published in:

Angewandte Chemie, 2019, v. 131, n. 10, p. 3146, doi. 10.1002/ange.201812697

By:

Beveridge, Rebecca;
Migas, Lukasz G.;
Kriwacki, Richard W.;
Barran, Perdita E.

Publication type:

Article

Initial Steps of Amyloidogenic Peptide Assembly Revealed by Cold-Ion Spectroscopy.

Published in:

Angewandte Chemie, 2018, v. 130, n. 1, p. 219, doi. 10.1002/ange.201710188

By:

Ujma, Jakub;
Kopysov, Vladimir;
Nagornova, Natalia S.;
Migas, Lukasz G.;
Lizio, Maria Giovanna;
Blanch, Ewan W.;
MacPhee, Cait;
Boyarkin, Oleg V.;
Barran, Perdita E.

Publication type:

Article

Dynamics of Intact Immunoglobulin G Explored by Drift-Tube Ion-Mobility Mass Spectrometry and Molecular Modeling.

Published in:

Angewandte Chemie, 2014, v. 126, n. 30, p. 7899, doi. 10.1002/ange.201402863

By:

Pacholarz, Kamila J.;
Porrini, Massimiliano;
Garlish, Rachel A.;
Burnley, Rebecca J.;
Taylor, Richard J.;
Henry, Alistair J.;
Barran, Perdita E.

Publication type:

Article

New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.

Published in:

Nature, 2015, v. 522, n. 7557, p. 497, doi. 10.1038/nature14560

By:

Payne, Karl A. P.;
White, Mark D.;
Fisher, Karl;
Khara, Basile;
Bailey, Samuel S.;
Parker, David;
Rattray, Nicholas J. W.;
Trivedi, Drupad K.;
Goodacre, Royston;
Beveridge, Rebecca;
Barran, Perdita;
Rigby, Stephen E. J.;
Scrutton, Nigel S.;
Hay, Sam;
Leys, David

Publication type:

Article

Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli.

Published in:

Biochemical Journal, 2024, v. 481, n. 11, p. 669, doi. 10.1042/BCJ20240019

By:

Brudenell, Emma L.;
Pohare, Manoj B.;
Zafred, Domen;
Phipps, Janine;
Hornsby, Hailey R.;
Darby, John F.;
Junxiao Dai;
Liggett, Ellen;
Cain, Kathleen M.;
Barran, Perdita E.;
de Silva, Thushan I.;
Sayers, Jon R.

Publication type:

Article

Probing the Conformational Diversity of Cancer-Associated Mutations in p53 with Ion-Mobility Mass Spectrometry.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 16, p. 4370, doi. 10.1002/anie.201210015

By:

Jurneczko, Ewa;
Cruickshank, Faye;
Porrini, Massimiliano;
Clarke, David J.;
Campuzano, Iain D. G.;
Morris, Michael;
Nikolova, Penka V.;
Barran, Perdita E.

Publication type:

Article

Sequential, Kinetically Controlled Synthesis of Multicomponent Stereoisomeric Assemblies.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 17, p. 4194, doi. 10.1002/anie.201108994

By:

Chepelin, Oleg;
Ujma, Jakub;
Barran, Perdita E.;
Lusby, Paul J.

Publication type:

Article

Inside Cover: Sequential, Kinetically Controlled Synthesis of Multicomponent Stereoisomeric Assemblies (Angew. Chem. Int. Ed. 17/2012).

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 17, p. 3978, doi. 10.1002/anie.201201577

By:

Chepelin, Oleg;
Ujma, Jakub;
Barran, Perdita E.;
Lusby, Paul J.

Publication type:

Article

Back Cover: Active-Metal Template Synthesis of a Molecular Trefoil Knot (Angew. Chem. Int. Ed. 51/2011).

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 51, p. 12366, doi. 10.1002/anie.201106646

By:

Barran, Perdita E.;
Cole, Harriet L.;
Goldup, Stephen M.;
Leigh, David A.;
McGonigal, Paul R.;
Symes, Mark D.;
Wu, Jhenyi;
Zengerle, Michael

Publication type:

Article

Active-Metal Template Synthesis of a Molecular Trefoil Knot.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 51, p. 12280, doi. 10.1002/anie.201105012

By:

Barran, Perdita E.;
Cole, Harriet L.;
Goldup, Stephen M.;
Leigh, David A.;
McGonigal, Paul R.;
Symes, Mark D.;
Wu, Jhenyi;
Zengerle, Michael

Publication type:

Article

(Re)Solution of a Protein Fold Without Solution.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 14, p. 3120, doi. 10.1002/anie.201007231

By:

Barran, Perdita E.

Publication type:

Article

Characterizing Early Aggregates Formed by an Amyloidogenic Peptide by Mass Spectrometry.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 49, p. 9448, doi. 10.1002/anie.201003373

By:

Cole, Harriet L.;
Kalapothakis, Jason M. D.;
Bennett, Guy;
Barran, Perdita E.;
MacPhee, Cait E.

Publication type:

Article

Conformation of glycosaminoglycans by ion mobility mass spectrometry.

Published in:

2004

By:

Lan Jin;
Barran, Perdita E.;
Lyon, Malcolm;
Uhrín, Dušan

Publication type:

Abstract

An integrated analysis and comparison of serum, saliva and sebum for COVID-19 metabolomics.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16123-4

By:

Spick, Matt;
Lewis, Holly-May;
Frampas, Cecile F.;
Longman, Katie;
Costa, Catia;
Stewart, Alexander;
Dunn-Walters, Deborah;
Greener, Danni;
Evetts, George;
Wilde, Michael J.;
Sinclair, Eleanor;
Barran, Perdita E.;
Skene, Debra J.;
Bailey, Melanie J.

Publication type:

Article

Untargeted saliva metabolomics by liquid chromatography—Mass spectrometry reveals markers of COVID-19 severity.

Published in:

PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0274967

By:

Frampas, Cecile F.;
Longman, Katie;
Spick, Matt;
Lewis, Holly-May;
Costa, Catia D. S.;
Stewart, Alex;
Dunn-Walters, Deborah;
Greener, Danni;
Evetts, George;
Skene, Debra J.;
Trivedi, Drupad;
Pitt, Andy;
Hollywood, Katherine;
Barran, Perdita;
Bailey, Melanie J.

Publication type:

Article

Protein Structure.

Published in:

2015

By:

Barran, Perdita;
Cooper, Helen;
Eyers, Claire

Publication type:

Editorial

Relating gas phase to solution conformations: Lessons from disordered proteins.

Published in:

Proteomics, 2015, v. 15, n. 16, p. 2872, doi. 10.1002/pmic.201400605

By:

Beveridge, Rebecca;
Phillips, Ashley S.;
Denbigh, Laetitia;
Saleem, Hassan M.;
MacPhee, Cait E.;
Barran, Perdita E.

Publication type:

Article

Nanohoops Favour Light‐Induced Energy Transfer over Charge Separation in Porphyrin/[10]CPP/Fullerene Rotaxanes.

Published in:

Angewandte Chemie, 2025, v. 137, n. 1, p. 1, doi. 10.1002/ange.202413404

By:

Schwer, Fabian;
Zank, Simon;
Freiberger, Markus;
Steudel, Fabian M.;
Geue, Niklas;
Ye, Lei;
Barran, Perdita E.;
Drewello, Thomas;
Guldi, Dirk M.;
von Delius, Max

Publication type:

Article

Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage**.

Published in:

Angewandte Chemie, 2022, v. 134, n. 25, p. 1, doi. 10.1002/ange.202115047

By:

Norgate, Emma L.;
Upton, Rosie;
Hansen, Kjetil;
Bellina, Bruno;
Brookes, C.;
Politis, Argyris;
Barran, Perdita E.

Publication type:

Article

Deciphering the safeguarding role of cysteine residues in p53 against H2O2-induced oxidation using high-resolution native mass spectrometry.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-024-01395-w

By:

Peris-Díaz, Manuel David;
Krężel, Artur;
Barran, Perdita

Publication type:

Article