Found: 32
Select item for more details and to access through your institution.
Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 10, p. 5928, doi. 10.1093/nar/gkae137
- By:
- Publication type:
- Article
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit.
- Published in:
- Neurology & Therapy, 2023, v. 12, n. 6, p. 1821, doi. 10.1007/s40120-023-00548-8
- By:
- Publication type:
- Article
The MLO-down on TDP-43.
- Published in:
- Brain: A Journal of Neurology, 2023, v. 146, n. 9, p. 3565, doi. 10.1093/brain/awad268
- By:
- Publication type:
- Article
C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD.
- Published in:
- Acta Neuropathologica, 2023, v. 145, n. 6, p. 793, doi. 10.1007/s00401-023-02565-1
- By:
- Publication type:
- Article
miRNA analysis reveals novel dysregulated pathways in amyotrophic lateral sclerosis.
- Published in:
- Human Molecular Genetics, 2023, v. 32, n. 6, p. 934, doi. 10.1093/hmg/ddac250
- By:
- Publication type:
- Article
Ubiquilin-2 regulates pathological alpha-synuclein.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-022-26899-0
- By:
- Publication type:
- Article
Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-12191-8
- By:
- Publication type:
- Article
CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins.
- Published in:
- Nucleic Acids Research, 2022, v. 50, n. 15, p. 8674, doi. 10.1093/nar/gkac626
- By:
- Publication type:
- Article
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30387-4
- By:
- Publication type:
- Article
Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-12191-8
- By:
- Publication type:
- Article
TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Enhanced detection of expanded repeat mRNA foci with hybridization chain reaction.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01169-8
- By:
- Publication type:
- Article
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
- Published in:
- 2021
- By:
- Publication type:
- journal article
The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-01002-8
- By:
- Publication type:
- Article
Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis.
- Published in:
- Frontiers in Cellular Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fncel.2020.00117
- By:
- Publication type:
- Article
Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS.
- Published in:
- 2020
- By:
- Publication type:
- journal article
DDX3X and specific initiation factors modulate FMR1 repeat‐associated non‐AUG‐initiated translation.
- Published in:
- EMBO Reports, 2019, v. 20, n. 9, p. N.PAG, doi. 10.15252/embr.201847498
- By:
- Publication type:
- Article
RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02200-0
- By:
- Publication type:
- Article
Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis.
- Published in:
- PLoS Genetics, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.pgen.1006805
- By:
- Publication type:
- Article
Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity.
- Published in:
- PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0165084
- By:
- Publication type:
- Article
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.
- Published in:
- Nature Chemical Biology, 2014, v. 10, n. 8, p. 677, doi. 10.1038/nchembio.1563
- By:
- Publication type:
- Article
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
- Published in:
- Journal of Clinical Investigation, 2014, v. 124, n. 3, p. 981, doi. 10.1172/JCI72723
- By:
- Publication type:
- Article
Comment on "Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells".
- Published in:
- Science Translational Medicine, 2013, v. 5, n. 188, p. 1, doi. 10.1126/scitranslmed.3005065
- By:
- Publication type:
- Article
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.
- Published in:
- Nature Genetics, 2012, v. 44, n. 12, p. 1302, doi. 10.1038/ng.2434
- By:
- Publication type:
- Article
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
- Published in:
- 2012
- By:
- Publication type:
- journal article
Progranulin deficienc y promotes neuroinflammation and neuron loss following toxin-induced injury.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 11, p. 3955, doi. 10.1172/JCI63113
- By:
- Publication type:
- Article
Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 2, p. 639, doi. 10.1523/JNEUROSCI.4988-09.2010
- By:
- Publication type:
- Article
Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice.
- Published in:
- EMBO Journal, 2007, v. 26, n. 11, p. 2777, doi. 10.1038/sj.emboj.7601726
- By:
- Publication type:
- Article
Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans.
- Published in:
- EMBO Journal, 2007, v. 26, n. 4, p. 935, doi. 10.1038/sj.emboj.7601540
- By:
- Publication type:
- Article
N-Terminally Deleted Forms of the Prion Protein Activate Both Bax-Dependent and Bax-Independent Neurotoxic Pathways.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 4, p. 852, doi. 10.1523/JNEUROSCI.4244-06.2007
- By:
- Publication type:
- Article
Visualization of Prion Infection in Transgenic Mice Expressing Green Fluorescent Protein-Tagged Prion Protein.
- Published in:
- Journal of Neuroscience, 2005, v. 25, n. 24, p. 5824, doi. 10.1523/JNEUROSCI.1192-05.2005
- By:
- Publication type:
- Article
Transgene-coded chimeric proteins as reporters of intracellular proteolysis: Starvation-induced catabolism of a lacZ fusion protein in muscle cells of Caenorhabditis elegans.
- Published in:
- Journal of Cellular Biochemistry, 1997, v. 67, n. 1, p. 143, doi. 10.1002/(SICI)1097-4644(19971001)67:1<143::AID-JCB15>3.0.CO;2-I
- By:
- Publication type:
- Article