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Integrating predicted transcriptome from multiple tissues improves association detection.
Published in:
PLoS Genetics, 2019, v. 15, n. 1, p. 1, doi. 10.1371/journal.pgen.1007889
By:
- Barbeira, Alvaro N.;
- Pividori, Milton D.;
- Zheng, Jiamao;
- Wheeler, Heather E.;
- Nicolae, Dan L.;
- Im, Hae Kyung
Publication type:
Article
Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.
Published in:
Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-020-02252-4
By:
- Barbeira, Alvaro N.;
- Bonazzola, Rodrigo;
- Gamazon, Eric R.;
- Liang, Yanyu;
- Park, YoSon;
- Kim-Hellmuth, Sarah;
- Wang, Gao;
- Jiang, Zhuoxun;
- Zhou, Dan;
- Hormozdiari, Farhad;
- Liu, Boxiang;
- Rao, Abhiram;
- Hamel, Andrew R.;
- Pividori, Milton D.;
- Aguet, François;
- Bastarache, Lisa;
- Jordan, Daniel M.;
- Verbanck, Marie;
- Do, Ron;
- Stephens, Matthew
Publication type:
Article
sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression.
Published in:
Genome Biology, 2020, v. 21, p. 1, doi. 10.1186/s13059-020-02129-6
By:
- He, Yuan;
- Chhetri, Surya B.;
- Arvanitis, Marios;
- Srinivasan, Kaushik;
- Aguet, François;
- Ardlie, Kristin G.;
- Barbeira, Alvaro N.;
- Bonazzola, Rodrigo;
- Im, Hae Kyung;
- Brown, Christopher D.;
- Battle, Alexis
Publication type:
Article
Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx.
Published in:
Genome Biology, 2020, v. 21, p. 1, doi. 10.1186/s13059-020-02113-0
By:
- Gay, Nicole R.;
- Gloudemans, Michael;
- Antonio, Margaret L.;
- Abell, Nathan S.;
- Balliu, Brunilda;
- Park, YoSon;
- Martin, Alicia R.;
- Musharoff, Shaila;
- Rao, Abhiram S.;
- Aguet, François;
- Barbeira, Alvaro N.;
- Bonazzola, Rodrigo;
- Hormozdiari, Farhad;
- Ardlie, Kristin G.;
- Brown, Christopher D.;
- Im, Hae Kyung;
- Lappalainen, Tuuli;
- Wen, Xiaoquan;
- Montgomery, Stephen B.
Publication type:
Article
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03621-1
By:
- Barbeira, Alvaro N.;
- Dickinson, Scott P.;
- Bonazzola, Rodrigo;
- Jiamao Zheng;
- Wheeler, Heather E.;
- Torres, Jason M.;
- Torstenson, Eric S.;
- Shah, Kaanan P.;
- Garcia, Tzintzuni;
- Edwards, Todd L.;
- Stahl, Eli A.;
- Huckins, Laura M.;
- Nicolae, Dan L.;
- Cox, Nancy J.;
- Hae Kyung Im
Publication type:
Article
Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity.
Published in:
Genome Biology, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s13059-018-1507-0
By:
- Geeleher, Paul;
- Nath, Aritro;
- Wang, Fan;
- Zhang, Zhenyu;
- Barbeira, Alvaro N.;
- Fessler, Jessica;
- Grossman, Robert L.;
- Seoighe, Cathal;
- Stephanie Huang, R.
Publication type:
Article
Fine‐mapping and QTL tissue‐sharing information improves the reliability of causal gene identification.
Published in:
Genetic Epidemiology, 2020, v. 44, n. 8, p. 854, doi. 10.1002/gepi.22346
By:
- Barbeira, Alvaro N.;
- Melia, Owen J.;
- Liang, Yanyu;
- Bonazzola, Rodrigo;
- Wang, Gao;
- Wheeler, Heather E.;
- Aguet, François;
- Ardlie, Kristin G.;
- Wen, Xiaoquan;
- Im, Hae K.
Publication type:
Article
Imputed gene associations identify replicable trans‐acting genes enriched in transcription pathways and complex traits.
Published in:
Genetic Epidemiology, 2019, v. 43, n. 6, p. 596, doi. 10.1002/gepi.22205
By:
- Wheeler, Heather E.;
- Ploch, Sally;
- Barbeira, Alvaro N.;
- Bonazzola, Rodrigo;
- Andaleon, Angela;
- Fotuhi Siahpirani, Alireza;
- Saha, Ashis;
- Battle, Alexis;
- Roy, Sushmita;
- Im, Hae Kyung
Publication type:
Article
A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21592-8
By:
- Yanyu Liang;
- Aguet, François;
- Barbeira, Alvaro N.;
- Ardlie, Kristin;
- Hae Kyung Im
Publication type:
Article

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