Found: 40
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Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2.
- Published in:
- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0868-6
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- Publication type:
- Article
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.
- Published in:
- Science Translational Medicine, 2022, v. 14, n. 667, p. 1, doi. 10.1126/scitranslmed.abo7219
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- Publication type:
- Article
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 541, p. 1, doi. 10.1126/scitranslmed.aaz2415
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- Publication type:
- Article
Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics.
- Published in:
- 2012
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- Publication type:
- journal article
Egisto Boschetti and Pier Giorgio Righetti: Low-abundance proteome discovery: state of the art and protocols.
- Published in:
- 2014
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- Publication type:
- Book Review
Differential proteome analysis and mass spectrometric characterization of germ line development-related proteins of Caenorhabditis elegans.
- Published in:
- Proteomics, 2004, v. 4, n. 8, p. 2283, doi. 10.1002/pmic.200400807
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- Publication type:
- Article
Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs.
- Published in:
- Angewandte Chemie, 2021, v. 133, n. 43, p. 23515, doi. 10.1002/ange.202109237
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- Publication type:
- Article
A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19529-8
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- Publication type:
- Article
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
- Published in:
- Science Immunology, 2021, v. 6, n. 58, p. 1, doi. 10.1126/sciimmunol.abg0833
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- Publication type:
- Article
Femtomol sensitivity post-digest <sup>18</sup>O labeling for relative quantification of differential protein complex composition.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2004, v. 18, n. 8, p. 869, doi. 10.1002/rcm.1418
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- Publication type:
- Article
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.
- Published in:
- Acta Neuropathologica, 2017, v. 133, n. 5, p. 731, doi. 10.1007/s00401-016-1663-9
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- Publication type:
- Article
Chemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50335-5
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- Publication type:
- Article
New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.
- Published in:
- Nature Chemical Biology, 2015, v. 11, n. 11, p. 878, doi. 10.1038/nchembio.1930
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- Publication type:
- Article
Catalytic in vivo protein knockdown by small-molecule PROTACs.
- Published in:
- Nature Chemical Biology, 2015, v. 11, n. 8, p. 611, doi. 10.1038/nchembio.1858
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- Publication type:
- Article
Mass-spectrometry-based draft of the human proteome.
- Published in:
- Nature, 2014, v. 509, n. 7502, p. 1, doi. 10.1038/nature13319
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- Publication type:
- Article
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
- Published in:
- Nature, 2012, v. 488, n. 7411, p. 404, doi. 10.1038/nature11262
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- Publication type:
- Article
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
- Published in:
- Nature, 2011, v. 478, n. 7370, p. 529, doi. 10.1038/nature10509
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- Publication type:
- Article
Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles.
- Published in:
- 2021
- By:
- Publication type:
- Correction Notice
Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 43, p. 23327, doi. 10.1002/anie.202109237
- By:
- Publication type:
- Article
One‐Step Synthesis of Photoaffinity Probes for Live‐Cell MS‐Based Proteomics.
- Published in:
- Chemistry - A European Journal, 2021, v. 27, n. 71, p. 17880, doi. 10.1002/chem.202102036
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- Publication type:
- Article
Systematic analysis of protein turnover in primary cells.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03106-1
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- Publication type:
- Article
Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition.
- Published in:
- Nature Communications, 2016, v. 7, n. 11, p. 13312, doi. 10.1038/ncomms13312
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- Publication type:
- Article
An improved two-step calibration method for matrix-assisted laser desorption/ionization time-of-flight mass spectra for proteomics.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2002, v. 16, n. 19, p. 1892, doi. 10.1002/rcm.798
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- Publication type:
- Article
Identification of proteins that form complexes with tau in mouse brain
- Published in:
- 2010
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- Publication type:
- Abstract
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.
- Published in:
- Science Translational Medicine, 2017, v. 9, n. 387, p. 1, doi. 10.1126/scitranslmed.aad9735
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- Publication type:
- Article
Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis.
- Published in:
- Electrophoresis, 2002, v. 23, n. 19, p. 3445, doi. 10.1002/1522-2683(200210)23:19<3445::AID-ELPS3445>3.0.CO;2-J
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- Publication type:
- Article
A Bayesian semi-parametric model for thermal proteome profiling.
- Published in:
- Communications Biology, 2021, v. 4, p. 1, doi. 10.1038/s42003-021-02306-8
- By:
- Publication type:
- Article
Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines.
- Published in:
- G3: Genes | Genomes | Genetics, 2020, v. 10, n. 5, p. 1585, doi. 10.1534/g3.119.401031
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- Publication type:
- Article
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry.
- Published in:
- Nature Protocols, 2015, v. 10, n. 10, p. 1567, doi. 10.1038/nprot.2015.101
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- Publication type:
- Article
Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present.
- Published in:
- Analytical & Bioanalytical Chemistry, 2012, v. 404, n. 4, p. 939, doi. 10.1007/s00216-012-6203-4
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- Publication type:
- Article
Quantitative mass spectrometry in proteomics.
- Published in:
- 2012
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- Publication type:
- Editorial
Quantitative mass spectrometry in proteomics: a critical review.
- Published in:
- Analytical & Bioanalytical Chemistry, 2007, v. 389, n. 4, p. 1017, doi. 10.1007/s00216-007-1486-6
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- Publication type:
- Article
Proteome Analysis of Diseased Joints from Mice Suffering from Collagen-Induced Arthritis.
- Published in:
- Clinical Chemistry & Laboratory Medicine, 2003, v. 41, n. 12, p. 1622, doi. 10.1515/CCLM.2003.246
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- Publication type:
- Article
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.
- Published in:
- Nature Biotechnology, 2011, v. 29, n. 3, p. 255, doi. 10.1038/nbt.1759
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- Publication type:
- Article
Human Proteinpedia enables sharing of human protein data.
- Published in:
- 2008
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- Publication type:
- Letter
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.
- Published in:
- Nature Biotechnology, 2007, v. 25, n. 9, p. 1035, doi. 10.1038/nbt1328
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- Publication type:
- Article
Drug-perturbation-based stratification of blood cancer.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09107-y
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- Publication type:
- Article
Pathway Proteomics and Chemical Proteomics Team Up in Drug Discovery.
- Published in:
- Neurodegenerative Diseases, 2007, v. 4, n. 2/3, p. 270, doi. 10.1159/000101851
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- Publication type:
- Article
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition.
- Published in:
- Molecular Systems Biology, 2024, v. 20, n. 4, p. 458, doi. 10.1038/s44320-024-00025-w
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- Publication type:
- Article