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Persistent GDNF Expression 45 Months after Putaminal Infusion of AAV2‐GDNF in a Patient with Parkinson's Disease.
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- Movement Disorders, 2024, v. 39, n. 8, p. 1412, doi. 10.1002/mds.29820
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- Publication type:
- Article
Differences between lentiviral vector--mediated ex vivo hematopoietic stem cell and adeno-associated virus gene therapies for neurological disorders.
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- Journal of Neurosurgery, 2022, v. 136, n. 5, p. 1501, doi. 10.3171/2021.10.JNS212466.
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- Publication type:
- Article
Use of a novel ball-joint guide array for magnetic resonance imaging--guided cannula placement and convective delivery: technical note.
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- Journal of Neurosurgery, 2021, v. 135, n. 2, p. 651, doi. 10.3171/2020.6.JNS201564
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- Publication type:
- Article
Direct convective delivery of adeno-associated virus gene therapy for treatment of neurological disorders.
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- Journal of Neurosurgery, 2021, v. 134, n. 6, p. 1751, doi. 10.3171/2020.4.JNS20701
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- Publication type:
- Article
Chronic convection-enhanced delivery: the next frontier in regional drug infusion for glioblastoma.
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- Journal of Neurosurgery, 2020, v. 133, n. 3, p. 611, doi. 10.3171/2019.4.jns19614
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- Publication type:
- Article
Infuse-as-you-go convective delivery to enhance coverage of elongated brain targets: technical note.
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- Journal of Neurosurgery, 2020, v. 133, n. 2, p. 530, doi. 10.3171/2019.4.JNS19826
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- Publication type:
- Article
Aromatic L-Amino Acid Decarboxylase Gene Therapy Enhances Levodopa Response in Parkinson's Disease.
- Published in:
- 2020
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- Publication type:
- journal article
Development of a novel frameless skull-mounted ball-joint guide array for use in image-guided neurosurgery.
- Published in:
- Journal of Neurosurgery, 2020, v. 132, n. 2, p. 595, doi. 10.3171/2018.10.JNS182169
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- Publication type:
- Article
Adeno-associated viral vector serotype 9–based gene therapy for Niemann-Pick disease type A.
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- Science Translational Medicine, 2019, v. 11, n. 506, p. 1, doi. 10.1126/scitranslmed.aat3738
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- Article
Trial of magnetic resonance-guided putaminal gene therapy for advanced Parkinson's disease.
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- 2019
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- Publication type:
- journal article
Magnetic resonance imaging-guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease.
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- 2019
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- Publication type:
- journal article
P2‐027: TARGET ENGAGEMENT IN A PHASE II CLINICAL TRIAL OF AAV2‐NGF GENE THERAPY FOR ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P677, doi. 10.1016/j.jalz.2018.06.711
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- Publication type:
- Article
Transplantation of Neural Progenitor Cells Expressing Glial Cell Line‐Derived Neurotrophic Factor into the Motor Cortex as a Strategy to Treat Amyotrophic Lateral Sclerosis.
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- Stem Cells, 2018, v. 36, n. 7, p. 1122, doi. 10.1002/stem.2825
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- Publication type:
- Article
Real-time MRI-guided intraputaminal AADC gene therapy for advanced Parkinson's disease.
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- Stereotactic & Functional Neurosurgery, 2017, v. 95, p. 170
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- Publication type:
- Article
Depletion of AADC activity in caudate nucleus and putamen of Parkinson’s disease patients; implications for ongoing AAV2-AADC gene therapy trial.
- Published in:
- PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0169965
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- Publication type:
- Article
Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse.
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- Addiction Biology, 2015, v. 20, n. 4, p. 629, doi. 10.1111/adb.12152
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- Publication type:
- Article
Transduction of antigen-presenting cells in the brain by AAV9 warrants caution in preclinical studies.
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- Molecular Therapy, 2015, v. 23, n. 4, p. 612, doi. 10.1038/mt.2015.35
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- Publication type:
- Article
AAV9-mediated Expression of a Non-self Protein in Nonhuman Primate Central Nervous System Triggers Widespread Neuroinflammation Driven by Antigen-presenting Cell Transduction.
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- Molecular Therapy, 2014, v. 22, n. 2, p. 329, doi. 10.1038/mt.2013.266
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- Publication type:
- Article
Automated Segmentation Tool for Brain Infusions.
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- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0064452
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- Publication type:
- Article
Rapid Inverse Planning for Pressure-Driven Drug Infusions in the Brain.
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- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056397
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- Publication type:
- Article
Cerebral Infusion of AAV9 Vector-encoding Non-self Proteins Can Elicit Cell-mediated Immune Responses.
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- Molecular Therapy, 2013, v. 21, n. 1, p. 158, doi. 10.1038/mt.2012.167
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- Publication type:
- Article
Evaluation of pressure-driven brain infusions in nonhuman primates by intra-operative 7 tesla MRI.
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- Journal of Magnetic Resonance Imaging, 2012, v. 36, n. 6, p. 1339, doi. 10.1002/jmri.23771
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- Publication type:
- Article
Merits of Combination Cortical, Subcortical, and Cerebellar Injections for the Treatment of Niemann-Pick Disease Type A.
- Published in:
- Molecular Therapy, 2012, v. 20, n. 10, p. 1893, doi. 10.1038/mt.2012.118
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- Publication type:
- Article
Evaluation of an AAV2-Based Rapamycin-Regulated Glial Cell Line-Derived Neurotrophic Factor (GDNF) Expression Vector System.
- Published in:
- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027728
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- Publication type:
- Article
AAV9: Over the Fence and Into the Woods . . .
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- Molecular Therapy, 2011, v. 19, n. 6, p. 1006, doi. 10.1038/mt.2011.95
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- Publication type:
- Article
Interventional MRI-guided Putaminal Delivery of AAV2-GDNF for a Planned Clinical Trial in Parkinson's Disease.
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- Molecular Therapy, 2011, v. 19, n. 6, p. 1048, doi. 10.1038/mt.2011.11
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- Publication type:
- Article
Novel Platform for MRI-Guided Convection-Enhanced Delivery of Therapeutics: Preclinical Validation in Nonhuman Primate Brain.
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- Stereotactic & Functional Neurosurgery, 2011, v. 89, n. 3, p. 141, doi. 10.1159/000323544
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- Publication type:
- Article
Anterograde Axonal Transport of AAV2-GDNF in Rat Basal Ganglia.
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- Molecular Therapy, 2011, v. 19, n. 5, p. 922, doi. 10.1038/mt.2010.248
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- Publication type:
- Article
The Use of Convection-Enhanced Delivery with Liposomal Toxins in Neurooncology.
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- Toxins, 2011, v. 3, n. 4, p. 369, doi. 10.3390/toxins3040369
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- Publication type:
- Article
An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease.
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- Journal of Neuroscience, 2010, v. 30, n. 49, p. 16469, doi. 10.1523/JNEUROSCI.2440-10.2010
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- Publication type:
- Article
An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 48, p. 16469, doi. 10.1523/JNEUROSCI.2440-10.2010
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- Publication type:
- Article
Canine spontaneous glioma: A translational model system for convection-enhanced delivery.
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- Neuro-Oncology, 2010, v. 12, n. 9, p. 928, doi. 10.1093/neuonc/noq046
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- Publication type:
- Article
Eight Years of Clinical Improvement in MPTP-Lesioned Primates After Gene Therapy With AAV2-hAADC.
- Published in:
- Molecular Therapy, 2010, v. 18, n. 8, p. 1458, doi. 10.1038/mt.2010.106
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- Publication type:
- Article
Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 Vectors.
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- Molecular Therapy, 2010, v. 18, n. 8, p. 1490, doi. 10.1038/mt.2010.114
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- Publication type:
- Article
Regeneration of the MPTP-Lesioned Dopaminergic System after Convection-Enhanced Delivery of AAV2-GDNF.
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- Journal of Neuroscience, 2010, v. 30, n. 28, p. 9567, doi. 10.1523/JNEUROSCI.0942-10.2010
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- Publication type:
- Article
Biodistribution of Adeno-associated Virus Type-2 in Nonhuman Primates after Convection-enhanced Delivery to Brain.
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- Molecular Therapy, 2008, v. 16, n. 7, p. 1267, doi. 10.1038/mt.2008.111
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- Publication type:
- Article
Long-Term Clinical Improvement in MPTP-Lesioned Primates after Gene Therapy with AAV-hAADC.
- Published in:
- Molecular Therapy, 2006, v. 14, n. 4, p. 564, doi. 10.1016/j.ymthe.2006.05.005
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- Publication type:
- Article
A Dose-Ranging Study of AAV-hAADC Therapy in Parkinsonian Monkeys.
- Published in:
- Molecular Therapy, 2006, v. 14, n. 4, p. 571, doi. 10.1016/j.ymthe.2006.04.008
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- Publication type:
- Article
Convection-enhanced delivery of Ls-TPT enables an effective, continuous, low-dose chemotherapy against malignant glioma xenograft model.
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- Neuro-Oncology, 2006, v. 8, n. 3, p. 205, doi. 10.1215/15228517-2006-001
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- Publication type:
- Article
241. A Dose-Ranging Study of AAV-hAADC Therapy in Parkinsonian Monkeys.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S93, doi. 10.1016/j.ymthe.2006.08.268
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- Publication type:
- Article
942. Evaluation of Short (8 Weeks) and Long-Term (3 and 5 Years) Gene Transfer Following Brain Delivery of AAV-AADC Vector in Parkinsonian Monkeys
- Published in:
- 2005
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- Publication type:
- Abstract