Found: 36
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A single‐centre study evaluating a geriatric screening tool in oncology phase I trial patients.
- Published in:
- Cancer Reports, 2024, v. 7, n. 6, p. 1, doi. 10.1002/cnr2.2083
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- Publication type:
- Article
Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39679-9
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- Publication type:
- Article
A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer.
- Published in:
- British Journal of Cancer, 2023, v. 129, n. 1, p. 38, doi. 10.1038/s41416-023-02279-x
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- Publication type:
- Article
Preliminary evidence of antitumour activity of Ipatasertib (Ipat) and Atezolizumab (ATZ) in glioblastoma patients (pts) with PTEN loss from the Phase 1 Ice-CAP trial (NCT03673787).
- Published in:
- 2021
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- Publication type:
- Abstract
A phospho-proteomic study of cetuximab resistance in KRAS/NRAS/BRAF<sup>V600</sup> wild-type colorectal cancer.
- Published in:
- Cellular Oncology (2211-3428), 2021, v. 44, n. 5, p. 1197, doi. 10.1007/s13402-021-00628-7
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- Publication type:
- Article
Searching for treatments for non-G12C-KRAS mutant cancers.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Correction to: Radiological evaluation of malignant pleural mesothelioma - defining distant metastatic disease.
- Published in:
- 2021
- By:
- Publication type:
- corrected article
Radiological evaluation of malignant pleural mesothelioma - defining distant metastatic disease.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Two Distinct Ways to Target KRAS-Mutant Tumors Hint at Efficacy.
- Published in:
- Journal of Oncology Navigation & Survivorship, 2020, v. 11, n. 8, p. 285
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- Publication type:
- Article
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15596-z
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- Publication type:
- Article
Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation.
- Published in:
- Metabolomics, 2020, v. 16, n. 4, p. 1, doi. 10.1007/s11306-020-01676-0
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- Publication type:
- Article
The kinase polypharmacology landscape of clinical PARP inhibitors.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59074-4
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- Publication type:
- Article
Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
- Published in:
- 2018
- By:
- Publication type:
- Correction Notice
Target-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
- Published in:
- 2018
- By:
- Publication type:
- corrected article
Safety, efficacy and survival of patients with primary malignant brain tumours (PMBT) in phase I (Ph1) trials: the 12-year Royal Marsden experience.
- Published in:
- Journal of Neuro-Oncology, 2018, v. 139, n. 1, p. 107, doi. 10.1007/s11060-018-2847-z
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- Publication type:
- Article
A Phase 1, open-label, multicentre study to compare the capsule and tablet formulations of AZD5363 and explore the effect of food on the pharmacokinetic exposure, safety and tolerability of AZD5363 in patients with advanced solid malignancies: OAK.
- Published in:
- 2018
- By:
- Publication type:
- journal article
A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments.
- Published in:
- PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186106
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- Publication type:
- Article
Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on-target ALK inhibitors in neuroblastoma.
- Published in:
- Molecular Oncology, 2017, v. 11, n. 8, p. 996, doi. 10.1002/1878-0261.12069
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- Publication type:
- Article
A study of motivations and expectations of patients seen in phase 1 oncology clinics.
- Published in:
- 2016
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- Publication type:
- journal article
Insights into significance of combined inhibition of MEK and m-TOR signalling output in KRAS mutant non-small-cell lung cancer.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Hyperglycemia and Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin (PI3K/AKT/mTOR) Inhibitors in Phase I Trials: Incidence, Predictive Factors, and Management.
- Published in:
- Oncologist, 2016, v. 21, n. 7, p. 855, doi. 10.1634/theoncologist.2015-0248
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- Publication type:
- Article
Characterisation of the Phosphatidylinositol 3-Kinase Pathway in Non-Small Cell Lung Cancer Cells Isolated from Pleural Effusions.
- Published in:
- Oncology, 2016, v. 90, n. 5, p. 280, doi. 10.1159/000444928
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- Publication type:
- Article
Antibody-drug conjugates--an emerging class of cancer treatment.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Percentage Change in Plasma Cytokeratin 18 Is Associated with Clinical Outcomes in Patients Receiving Pemetrexed and Carboplatin for the Adenocarcinoma Subtype of NSCLC.
- Published in:
- Oncology, 2015, v. 89, n. 1, p. 53, doi. 10.1159/000371711
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- Publication type:
- Article
Phase I trials in patients with relapsed, advanced upper gastrointestinal carcinomas: experience in a specialist unit.
- Published in:
- Gastric Cancer, 2014, v. 17, n. 4, p. 621, doi. 10.1007/s10120-013-0328-9
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- Publication type:
- Article
Multi-Purpose Utility of Circulating Plasma DNA Testing in Patients with Advanced Cancers.
- Published in:
- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0047020
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- Publication type:
- Article
Combinatorial drug therapy for cancer in the post-genomic era.
- Published in:
- Nature Biotechnology, 2012, v. 30, n. 7, p. 679, doi. 10.1038/nbt.2284
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- Publication type:
- Article
A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 1, p. 341, doi. 10.1007/s10637-010-9493-4
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- Publication type:
- Article
Effects of HSP90 inhibitor 17-allylamino-17 -demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy.
- Published in:
- BMC Research Notes, 2012, v. 5, n. 1, p. 250, doi. 10.1186/1756-0500-5-250
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- Publication type:
- Article
Revisiting the role of molecular targeted therapies in patients with brain metastases.
- Published in:
- Journal of Neuro-Oncology, 2011, v. 105, n. 3, p. 467, doi. 10.1007/s11060-011-0661-y
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- Publication type:
- Article
Outcomes of Patients with Metastatic Melanoma Treated with Molecularly Targeted Agents in Phase I Clinical Trials.
- Published in:
- Oncology, 2011, v. 81, n. 2, p. 135, doi. 10.1159/000330206
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- Publication type:
- Article
An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 769, doi. 10.1007/s00280-007-0662-x
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- Publication type:
- Article
Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.
- Published in:
- 2003
- By:
- Publication type:
- journal article
Magnetic Resonance Spectroscopic Pharmacodynamic Markers of the Heat Shock Protein 90 Inhibitor 17-Allylamino,17-Demethoxygeldanamycin (17AAG) in Human Color Cancer Models.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2003, v. 95, n. 21, p. 1624, doi. 10.1093/jnci/djg084
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- Publication type:
- Article
Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.
- Published in:
- Oncogene, 2000, v. 19, n. 36, p. 4125, doi. 10.1038/sj.onc.1203753
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- Publication type:
- Article