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LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation.
Published in:
2021
By:
- Pischedda, Francesca;
- Cirnaru, Maria Daniela;
- Ponzoni, Luisa;
- Sandre, Michele;
- Biosa, Alice;
- Carrion, Maria Perez;
- Marin, Oriano;
- Morari, Michele;
- Pan, Lifeng;
- Greggio, Elisa;
- Bandopadhyay, Rina;
- Sala, Mariaelvina;
- Piccoli, Giovanni
Publication type:
journal article
Clinical and pathological features of frontotemporal lobar degeneration with FUS-positive inclusions
Published in:
2010
By:
- Lashley, Tammaryn;
- Rohrer, Jonathan;
- Bandopadhyay, Rina;
- Ahmed, Zeshan;
- Borroni, Barbara;
- Warren, Jason D.;
- Troakes, Claire;
- King, Andrew;
- Al-Sarraj, Safa;
- Bojsen-Moller, Marie;
- Braendgaard, Hans;
- Fox, Nick C.;
- Rossor, Martin;
- Lees, Andrew J.;
- Holton, Janice L.;
- Revesz, Tamas
Publication type:
Abstract
P1-386: Analysis of the involvement of DJ-1 (Park-7) in AD, Pick’s and PSP
Published in:
2006
By:
- Kumaran, Ravindran;
- Lashley, Tammaryn;
- Kingsbury, Ann;
- Pittman, Alan;
- Mann, David;
- Lees, Andrew;
- de Silva, Rohan;
- Bandopadhyay, Rina
Publication type:
Abstract
P1-386: Analysis of the involvement of DJ-1 (Park-7) in AD, Pick’s and PSP
Published in:
2006
By:
- Kumaran, Ravindran;
- Lashley, Tammaryn;
- Kingsbury, Ann;
- Pittman, Alan;
- Mann, David;
- Lees, Andrew;
- de Silva, Rohan;
- Bandopadhyay, Rina
Publication type:
Abstract
Abnormal glycine metabolism in motor neurone disease: studies on plasma and cerebrospinal fluid.
Published in:
Journal of the Royal Society of Medicine, 1993, v. 86, n. 9, p. 501
By:
- Lane, Russell J. M.;
- Bandopadhyay, Rina;
- de Belleroche, Jackie
Publication type:
Article
Neuropathological features of genetically confirmed DYT1 dystonia: investigating disease-specific inclusions.
Published in:
Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/s40478-014-0159-x
By:
- Paudel, Reema;
- Kiely, Aoife;
- Li, Abi;
- Lashley, Tammaryn;
- Bandopadhyay, Rina;
- Hardy, John;
- Jinnah, Hyder;
- Bhatia, Kailash;
- Houlden, Henry;
- Holton, Janice
Publication type:
Article
mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1.
Published in:
Scientific Reports, 2016, p. 35106, doi. 10.1038/srep35106
By:
- Manzoni, Claudia;
- Mamais, Adamantios;
- Roosen, Dorien A.;
- Dihanich, Sybille;
- Soutar, Marc P. M.;
- Plun-Favreau, Helene;
- Bandopadhyay, Rina;
- Hardy, John;
- Tooze, Sharon A.;
- Cookson, Mark R.;
- Lewis, Patrick A.
Publication type:
Article
Phosphorylation of 4E-BP1 in the Mammalian Brain Is Not Altered by LRRK2 Expression or Pathogenic Mutations.
Published in:
PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047784
By:
- Trancikova, Alzbeta;
- Mamais, Adamantios;
- Webber, Philip J.;
- Stafa, Klodjan;
- Tsika, Elpida;
- Glauser, Liliane;
- West, Andrew B.;
- Bandopadhyay, Rina;
- Moore, Darren J.
Publication type:
Article
Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.
Published in:
PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022489
By:
- Devine, Michael J.;
- Kaganovich, Alice;
- Ryten, Mina;
- Mamais, Adamantios;
- Trabzuni, Daniah;
- Manzoni, Claudia;
- McGoldrick, Philip;
- Diane Chan;
- Dillman, Allissa;
- Zerle, Julia;
- Horan, Susannah;
- Taanman, Jan-Willem;
- Hardy, John;
- Marti-Masso, Jose-Felix;
- Healey, Daniel;
- Schapira, Anthony H.;
- Wolozin, Benjamin;
- Bandopadhyay, Rina;
- Cookson, Mark R.;
- van der Brug, Marcel P.
Publication type:
Article
A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies.
Published in:
Brain: A Journal of Neurology, 2011, v. 134, n. 9, p. 2548, doi. 10.1093/brain/awr160
By:
- Lashley, Tammaryn;
- Rohrer, Jonathan D.;
- Bandopadhyay, Rina;
- Fry, Charles;
- Ahmed, Zeshan;
- Isaacs, Adrian M.;
- Brelstaff, Jack H.;
- Borroni, Barbara;
- Warren, Jason D.;
- Troakes, Claire;
- King, Andrew;
- Al-Saraj, Safa;
- Newcombe, Jia;
- Quinn, Niall;
- Ostergaard, Karen;
- Schrøder, Henrik Daa;
- Bojsen-Møller, Marie;
- Braendgaard, Hans;
- Fox, Nick C.;
- Rossor, Martin N.
Publication type:
Article
Cellular processes associated with LRRK2 function and dysfunction.
Published in:
FEBS Journal, 2015, v. 282, n. 15, p. 2806, doi. 10.1111/febs.13305
By:
- Wallings, Rebecca;
- Manzoni, Claudia;
- Bandopadhyay, Rina
Publication type:
Article
GTP binding controls complex formation by the human ROCO protein MASL1.
Published in:
FEBS Journal, 2014, v. 281, n. 1, p. 261, doi. 10.1111/febs.12593
By:
- Dihanich, Sybille;
- Civiero, Laura;
- Manzoni, Claudia;
- Mamais, Adamantios;
- Bandopadhyay, Rina;
- Greggio, Elisa;
- Lewis, Patrick A.
Publication type:
Article
Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.
Published in:
2022
By:
- Mamais, Adamantios;
- Kluss, Jillian H.;
- Bonet-Ponce, Luis;
- Landeck, Natalie;
- Langston, Rebekah G.;
- Smith, Nathan;
- Beilina, Alexandra;
- Kaganovich, Alice;
- Ghosh, Manik C.;
- Pellegrini, Laura;
- Kumaran, Ravindran;
- Papazoglou, Ioannis;
- Heaton, George R.;
- Harvey, Kirsten;
- Bandopadhyay, Rina;
- Maio, Nunziata;
- Kim, Changyoun;
- LaVoie, Matthew J.;
- Gershlick, David C.;
- Cookson, Mark R.
Publication type:
Correction Notice
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.
Published in:
PLoS Biology, 2021, v. 19, n. 12, p. 1, doi. 10.1371/journal.pbio.3001480
By:
- Mamais, Adamantios;
- Kluss, Jillian H.;
- Bonet-Ponce, Luis;
- Landeck, Natalie;
- Langston, Rebekah G.;
- Smith, Nathan;
- Beilina, Alexandra;
- Kaganovich, Alice;
- Ghosh, Manik C.;
- Pellegrini, Laura;
- Kumaran, Ravindran;
- Papazoglou, Ioannis;
- Heaton, George R.;
- Bandopadhyay, Rina;
- Maio, Nunziata;
- Kim, Changyoun;
- LaVoie, Matthew J.;
- Gershlick, David C.;
- Cookson, Mark R.
Publication type:
Article
TDP-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degeneration and in other neurodegenerative diseases: a degenerative process distinct from normal ageing.
Published in:
Acta Neuropathologica, 2009, v. 118, n. 3, p. 359, doi. 10.1007/s00401-009-0526-z
By:
- Davidson, Yvonne;
- Amin, Hanan;
- Kelley, Thomas;
- Jing Shi;
- Jinzhou Tian;
- Kumaran, Ravindran;
- Lashley, Tammaryn;
- Lees, Andrew J.;
- DuPlessis, Daniel;
- Neary, David;
- Snowden, Julie;
- Akiyama, Haruhiko;
- Arai, Tetsuaki;
- Hasegawa, Masato;
- Bandopadhyay, Rina;
- Sikkink, Steve;
- Pickering-Brown, Stuart;
- Mann, David M. A.
Publication type:
Article
DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease.
Published in:
NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00485-1
By:
- Masato, Anna;
- Plotegher, Nicoletta;
- Terrin, Francesca;
- Sandre, Michele;
- Faustini, Gaia;
- Thor, Andrea;
- Adams, Stephen;
- Berti, Giulia;
- Cogo, Susanna;
- De Lazzari, Federica;
- Fontana, Camilla Maria;
- Martinez, Paul Anthony;
- Strong, Randy;
- Bandopadhyay, Rina;
- Bisaglia, Marco;
- Bellucci, Arianna;
- Greggio, Elisa;
- Dalla Valle, Luisa;
- Boassa, Daniela;
- Bubacco, Luigi
Publication type:
Article
Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain.
Published in:
Journal of Neurochemistry, 2015, v. 135, n. 6, p. 1242, doi. 10.1111/jnc.13369
By:
- Civiero, Laura;
- Cirnaru, Maria Daniela;
- Beilina, Alexandra;
- Rodella, Umberto;
- Russo, Isabella;
- Belluzzi, Elisa;
- Lobbestael, Evy;
- Reyniers, Lauran;
- Hondhamuni, Geshanthi;
- Lewis, Patrick A.;
- Van den Haute, Chris;
- Baekelandt, Veerle;
- Bandopadhyay, Rina;
- Bubacco, Luigi;
- Piccoli, Giovanni;
- Cookson, Mark R.;
- Taymans, Jean‐Marc;
- Greggio, Elisa
Publication type:
Article
Physiological and pathological roles of LRRK2 in the nuclear envelope integrity.
Published in:
Human Molecular Genetics, 2019, v. 28, n. 23, p. 3982, doi. 10.1093/hmg/ddz245
By:
- Shani, Vered;
- Safory, Hazem;
- Szargel, Raymonde;
- Wang, Ninghan;
- Cohen, Tsipora;
- Elghani, Fatimah Abd;
- Hamza, Haya;
- Savyon, Mor;
- Radzishevsky, Inna;
- Shaulov, Lihi;
- Rott, Ruth;
- Lim, Kah-Leong;
- Ross, Christopher A.;
- Bandopadhyay, Rina;
- Zhang, Hui;
- Engelender, Simone
Publication type:
Article
A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 18, p. 4887, doi. 10.1093/hmg/ddu202
By:
- Dusonchet, Julien;
- Li, Hu;
- Guillily, Maria;
- Liu, Min;
- Stafa, Klodjan;
- Derada Troletti, Claudio;
- Boon, Joon Y.;
- Saha, Shamol;
- Glauser, Liliane;
- Mamais, Adamantios;
- Citro, Allison;
- Youmans, Katherine L.;
- Liu, LiQun;
- Schneider, Bernard L.;
- Aebischer, Patrick;
- Yue, Zhenyu;
- Bandopadhyay, Rina;
- Glicksman, Marcie A.;
- Moore, Darren J.;
- Collins, James J.
Publication type:
Article
Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 17, p. 4621, doi. 10.1093/hmg/ddu178
By:
- Tsika, Elpida;
- Glauser, Liliane;
- Moser, Roger;
- Fiser, Aris;
- Daniel, Guillaume;
- Sheerin, Una-Marie;
- Lees, Andrew;
- Troncoso, Juan C.;
- Lewis, Patrick A.;
- Bandopadhyay, Rina;
- Schneider, Bernard L.;
- Moore, Darren J.
Publication type:
Article
Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 8, p. 2055, doi. 10.1093/hmg/ddt600
By:
- Stafa, Klodjan;
- Tsika, Elpida;
- Moser, Roger;
- Musso, Alessandra;
- Glauser, Liliane;
- Jones, Amy;
- Biskup, Saskia;
- Xiong, Yulan;
- Bandopadhyay, Rina;
- Dawson, Valina L.;
- Dawson, Ted M.;
- Moore, Darren J.
Publication type:
Article
AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease.
Published in:
Human Molecular Genetics, 2013, v. 22, n. 10, p. 2083, doi. 10.1093/hmg/ddt058
By:
- Haskin, Joseph;
- Szargel, Raymonde;
- Shani, Vered;
- Mekies, Lucy N.;
- Rott, Ruth;
- Lim, Grace G. Y.;
- Lim, Kah-Leong;
- Bandopadhyay, Rina;
- Wolosker, Herman;
- Engelender, Simone
Publication type:
Article
Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease.
Published in:
Acta Neuropathologica, 2022, v. 144, n. 1, p. 81, doi. 10.1007/s00401-022-02437-0
By:
- Iovino, Ludovica;
- Giusti, Veronica;
- Pischedda, Francesca;
- Giusto, Elena;
- Plotegher, Nicoletta;
- Marte, Antonella;
- Battisti, Ilaria;
- Di Iacovo, Angela;
- Marku, Algerta;
- Piccoli, Giovanni;
- Bandopadhyay, Rina;
- Perego, Carla;
- Bonifacino, Tiziana;
- Bonanno, Giambattista;
- Roseti, Cristina;
- Bossi, Elena;
- Arrigoni, Giorgio;
- Bubacco, Luigi;
- Greggio, Elisa;
- Hilfiker, Sabine
Publication type:
Article
Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies.
Published in:
Acta Neuropathologica, 2011, v. 122, n. 4, p. 415, doi. 10.1007/s00401-011-0857-4
By:
- Ahmed, Zeshan;
- Doherty, Karen;
- Silveira-Moriyama, Laura;
- Bandopadhyay, Rina;
- Lashley, Tammaryn;
- Mamais, Adamantios;
- Hondhamuni, Geshanthi;
- Wray, Selina;
- Newcombe, Jia;
- O'Sullivan, Sean;
- Wroe, Stephen;
- Silva, Rohan;
- Holton, Janice;
- Lees, Andrew;
- Revesz, Tamas
Publication type:
Article
Transportin1: a marker of FTLD-FUS.
Published in:
Acta Neuropathologica, 2011, v. 122, n. 5, p. 591, doi. 10.1007/s00401-011-0863-6
By:
- Brelstaff, Jack;
- Lashley, Tammaryn;
- Holton, Janice;
- Lees, Andrew;
- Rossor, Martin;
- Bandopadhyay, Rina;
- Revesz, Tamas
Publication type:
Article
Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2.
Published in:
Cells (2073-4409), 2024, v. 13, n. 1, p. 53, doi. 10.3390/cells13010053
By:
- Nazish, Iqra;
- Mamais, Adamantios;
- Mallach, Anna;
- Bettencourt, Conceicao;
- Kaganovich, Alice;
- Warner, Thomas;
- Hardy, John;
- Lewis, Patrick A.;
- Pocock, Jennifer;
- Cookson, Mark R.;
- Bandopadhyay, Rina
Publication type:
Article
Advances in the Understanding of Frontotemporal Dementia.
Published in:
Cells (2073-4409), 2023, v. 12, n. 5, p. 781, doi. 10.3390/cells12050781
By:
- Bandopadhyay, Rina;
- Gatt, Ariana;
- Lashley, Tammaryn
Publication type:
Article
Pathological Relevance of Post-Translationally Modified Alpha-Synuclein (pSer87, pSer129, nTyr39) in Idiopathic Parkinson's Disease and Multiple System Atrophy.
Published in:
Cells (2073-4409), 2022, v. 11, n. 5, p. 906, doi. 10.3390/cells11050906
By:
- Sonustun, Berkiye;
- Altay, Melek Firat;
- Strand, Catherine;
- Ebanks, Kirsten;
- Hondhamuni, Geshanthi;
- Warner, Thomas T.;
- Lashuel, Hilal A.;
- Bandopadhyay, Rina
Publication type:
Article
Perspective: Treatment for Disease Modification in Chronic Neurodegeneration.
Published in:
Cells (2073-4409), 2021, v. 10, n. 4, p. 873, doi. 10.3390/cells10040873
By:
- Müller, Thomas;
- Mueller, Bernhard Klaus;
- Riederer, Peter;
- Bézard, Erwan;
- Bandopadhyay, Rina
Publication type:
Article
Vesicular Dysfunction and the Pathogenesis of Parkinson's Disease: Clues From Genetic Studies.
Published in:
Frontiers in Neuroscience, 2020, v. 13, p. 1, doi. 10.3389/fnins.2019.01381
By:
- Ebanks, Kirsten;
- Lewis, Patrick A.;
- Bandopadhyay, Rina
Publication type:
Article
Improving the Gene Ontology Resource to Facilitate More Informative Analysis and Interpretation of Alzheimer's Disease Data.
Published in:
Genes, 2018, v. 9, n. 12, p. 593, doi. 10.3390/genes9120593
By:
- Kramarz, Barbara;
- Roncaglia, Paola;
- Meldal, Birgit H. M.;
- Huntley, Rachael P.;
- Martin, Maria J.;
- Orchard, Sandra;
- Parkinson, Helen;
- Brough, David;
- Bandopadhyay, Rina;
- Hooper, Nigel M.;
- Lovering, Ruth C.
Publication type:
Article
LRRK2 levels and phosphorylation in Parkinson's disease brain and cases with restricted Lewy bodies.
Published in:
2017
By:
- Dzamko, Nicolas;
- Gysbers, Amanda M.;
- Bandopadhyay, Rina;
- Bolliger, Marc F.;
- Uchino, Akiko;
- Zhao, Ye;
- Takao, Masaki;
- Wauters, Sandrine;
- Berg, Wilma D. J.;
- Takahashi‐Fujigasaki, Junko;
- Nichols, R. Jeremy;
- Holton, Janice L.;
- Murayama, Shigeo;
- Halliday, Glenda M.;
- van de Berg, Wilma D J;
- Takahashi-Fujigasaki, Junko
Publication type:
journal article
Brain stem pathology in Parkinson's disease: An evaluation of the Braak staging model.
Published in:
Movement Disorders, 2010, v. 25, n. 15, p. 2508, doi. 10.1002/mds.23305
By:
- Kingsbury, Ann E.;
- Bandopadhyay, Rina;
- Silveira-Moriyama, Laura;
- Ayling, Hilary;
- Kallis, Constantinos;
- Sterlacci, William;
- Maeir, Hans;
- Poewe, Werner;
- Lees, Andrew J.
Publication type:
Article
SIAH proteins regulate the degradation and intra‐mitochondrial aggregation of PINK1: Implications for mitochondrial pathology in Parkinson's disease.
Published in:
Aging Cell, 2022, v. 21, n. 12, p. 1, doi. 10.1111/acel.13731
By:
- Abd Elghani, Fatimah;
- Safory, Hazem;
- Hamza, Haya;
- Savyon, Mor;
- Farhoud, Malik;
- Toren‐Hershoviz, Michal;
- Vitic, Zagorka;
- Ebanks, Kirsten;
- Shani, Vered;
- Bisharat, Sleman;
- Shaulov, Lihi;
- Brodski, Claude;
- Song, Zhiyin;
- Bandopadhyay, Rina;
- Engelender, Simone
Publication type:
Article

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