Works by Balzarini, Jan
Results: 219
Prodrugs of γ‐Alkyl‐Modified Nucleoside Triphosphates: Improved Inhibition of HIV Reverse Transcriptase.
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- Angewandte Chemie, 2020, v. 132, n. 49, p. 22247, doi. 10.1002/ange.202003073
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- Article
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 1225, doi. 10.1080/14756366.2018.1493473
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Niacin esters of chalcones with tumor-selective properties.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1451, doi. 10.3109/14756366.2016.1144595
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- Article
Novel 1-acyl-4-substituted semicarbazide derivatives of primaquine − synthesis, cytostatic, antiviral and antioxidative studies.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 3, p. 601, doi. 10.3109/14756366.2012.663366
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Synthesis, antineoplastic and cytotoxic activities of some mononuclear Ru(II) complexes.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 4, p. 513, doi. 10.3109/14756360903357577
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Synthesis, antimicrobial and antiviral activity of substituted benzimidazoles.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 5, p. 1161, doi. 10.1080/14756360802694427
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1-Arylmethyl-2,3-dioxo-2,3-dihydroindole thiosemicarbazones as leads for developing cytotoxins and anticonvulsants.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 2, p. 537, doi. 10.1080/14756360802234885
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6-Azathymidine-4'-thionucleosides: synthesis and antiviral evaluation.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2008, v. 23, n. 1, p. 56, doi. 10.1080/14756360701442340
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- Article
Molecular modifications of 2-arylidene-1-indanones leading to increased cytotoxic potencies.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 1, p. 37, doi. 10.1080/14756360600958057
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Database Searching for Thymidine and Thymidylate Kinase Inhibitors Using Three-dimensional Structure-based Methods.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2002, v. 17, n. 3, p. 167, doi. 10.1080/14756360290032949
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- Article
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs
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- FEBS Letters, 2005, v. 579, n. 11, p. 2294, doi. 10.1016/j.febslet.2005.02.077
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Improved antiviral activity of the aryloxymethoxyalaninyl phosphoramidate (APA) prodrug of abacavir (ABC) is due to the formation of markedly increased carbovir 5<f><sup>′</sup></f>-triphosphate metabolite levels
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- FEBS Letters, 2004, v. 573, n. 1-3, p. 38, doi. 10.1016/j.febslet.2004.07.049
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Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase.
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- FEBS Letters, 2002, v. 510, n. 1-2, p. 83, doi. 10.1016/S0014-5793(01)03233-1
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Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base.
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- Canadian Journal of Chemistry, 2010, v. 88, n. 7, p. 628, doi. 10.1139/V10-054
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Synthesis and biological evaluation of 5-(alkyn-1-yl)-1-(p-toluenesulfonyl)uracil derivatives.
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- Canadian Journal of Chemistry, 2006, v. 84, n. 4, p. 580, doi. 10.1139/v06-041
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Design, Synthesis, and Biological Evaluation of Novel 2 H-Pyran-2-one Derivatives as Potential HIV-1 Reverse Transcriptase Inhibitors.
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- Archiv der Pharmazie, 2015, v. 348, n. 1, p. 23, doi. 10.1002/ardp.201400235
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1-Amino-3-(1 H-1,2,3-triazol-1-yl)propylphosphonates as Acyclic Analogs of Nucleotides.
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- Archiv der Pharmazie, 2014, v. 347, n. 7, p. 496, doi. 10.1002/ardp.201300471
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Novel Acyclic Phosphonylated 1,2,3-Triazolonucleosides with an Acetamidomethyl Linker: Synthesis and Biological Activity.
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- Archiv der Pharmazie, 2014, v. 347, n. 7, p. 506, doi. 10.1002/ardp.201300468
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Antiproliferative and Antiviral Activity of Three Libraries of Adamantane Derivatives.
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- Archiv der Pharmazie, 2014, v. 347, n. 5, p. 334, doi. 10.1002/ardp.201300345
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Design, Synthesis, Antiviral, and Cytostatic Evaluation of Novel Isoxazolidine Analogs of Homonucleotides.
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- Archiv der Pharmazie, 2014, v. 347, n. 5, p. 341, doi. 10.1002/ardp.201300382
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Synthesis of 1,2,3- Triazolyl Nucleoside Analogs as Potential Anti- Influenza A ( H3 N2 Subtype) Virus Agents.
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- Archiv der Pharmazie, 2014, v. 347, n. 2, p. 134, doi. 10.1002/ardp.201300260
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Synthesis of a New Series of Phosphonylated 1,2,3- Triazoles as Acyclic Analogs of Ribavirin.
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- Archiv der Pharmazie, 2013, v. 346, n. 9, p. 677, doi. 10.1002/ardp.201300156
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Synthesis and Biological Evaluation of Novel 1,2,3-Triazolonucleotides.
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- Archiv der Pharmazie, 2013, v. 346, n. 4, p. 278, doi. 10.1002/ardp.201200421
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- Article
Non-nucleoside HIV Reverse Transcriptase Inhibitors, Part 6[1]: Synthesis and Anti-HIV Activity of Novel 2-[(Arylcarbonylmethyl)thio]-6-arylthio DABO Analogues.
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- Archiv der Pharmazie, 2005, v. 338, n. 10, p. 457, doi. 10.1002/ardp.200400961
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Synthesis of 3-Nitrosoimidazo[1,2- a]pyridine Derivatives as Potential Antiretroviral Agents.
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- Archiv der Pharmazie, 2001, v. 334, n. 7, p. 224, doi. 10.1002/1521-4184(200107)334:7<224::AID-ARDP224>3.0.CO;2-7
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Synthesis and Antiviral and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclobutane Ring.
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- Archiv der Pharmazie, 1999, v. 332, n. 10, p. 348, doi. 10.1002/(SICI)1521-4184(199910)332:10<348::AID-ARDP348>3.0.CO;2-H
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Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues.
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- Archiv der Pharmazie, 1997, v. 330, n. 8, p. 265, doi. 10.1002/ardp.19973300807
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Synthesis of 5′- N-(α-Amino-β-mercaptoacyl)amino-5′-deoxynucleosides as potential antiviral compounds.
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- Archiv der Pharmazie, 1991, v. 324, n. 8, p. 497, doi. 10.1002/ardp.2503240807
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- Article
SYNTHESIS AND IN VITRO CYTOTOXIC AND ANTIVIRAL ACTIVITIES OF 1-(2,5,6-TRIDEOXY-6-HALOGENOHEPT-5-ENOFURANURONONITRILE)THYMINE AND DERIVATIVES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2002, v. 21, n. 3, p. 191, doi. 10.1081/NCN-120003285
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SYNTHESIS, ANTIVIRAL AND CYTOSTATIC ACTIVITIES, OF CARBOCYCLIC NUCLEOSIDES INCORPORATING A MODIFIED CYCLOPENTANE RING. IV. ADENOSINE AND URIDINE ANALOGUES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2002, v. 21, n. 3, p. 243, doi. 10.1081/NCN-120003289
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SYNTHESIS AND BIOLOGICAL EVALUATION OF ISONUCLEOSIDES DERIVED FROM METHYL 3,5-ANHYDRO-2-O-(2-FLUOROBENZYL)-d-XYLOFURANOSIDES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2002, v. 21, n. 3, p. 257, doi. 10.1081/NCN-120003290
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SYNTHESIS AND ANTI-HIV ACTIVITY OF THYMIDINE ANALOGUES BEARING A 4′-CYANOVINYL GROUP AND SOME DERIVATIVES THEREOF.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 12, p. 1927, doi. 10.1081/NCN-100108323
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THIOSUGARS. VIII.* PREPARATION OF NEW 4′-THIO-L-LYXO PYRIMIDINE NUCLEOSIDE ANALOGUES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 9, p. 1625, doi. 10.1081/NCN-100105900
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NOVEL ARYL SUBSTITUTED BICYCLIC FURO NUCLEOSIDES AS EXTREMELY POTENT AND SELECTIVE ANTI-VZV AGENTS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 287, doi. 10.1081/NCN-100002299
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SYNTHESIS AND IN VITRO EVALUATION OF NOVEL ANTI-VARICELLA-ZOSTER VIRUS (VZV) NUCLEOSIDES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 653, doi. 10.1081/NCN-100002343
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SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRIDIN-2-ONE NUCLEOSIDES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 731, doi. 10.1081/NCN-100002361
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BICYCLIC NUCLEOSIDE INHIBITORS OF VARICELLA-ZOSTER VIRUS (VZV): EFFECT OF TERMINAL UNSATURATION IN THE SIDE-CHAIN.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 763, doi. 10.1081/NCN-100002425
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BICYCLIC FURO PYRIMIDINE NUCLEOSIDES WITH ARYLOXYPHENYL AND HALOPHENYL SUBSTITUTED SIDE CHAINS AS POTENT AND SELECTIVE VARICELLA-ZOSTER VIRUS INHIBITORS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 1063, doi. 10.1081/NCN-100002492
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SYNTHESIS OF 1-(2-DEOXY-β-D- RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENE THYMIDINE MIMICS,* SOME RELATED α-ANOMERS, AND THEIR EVALUATION AS ANTIVIRAL AND ANTICANCER AGENTS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 1/2, p. 11, doi. 10.1081/NCN-100001435
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SYNTHESIS OF 1-(2-DEOXY-β-D-RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENES*: “THYMINE REPLACEMENT” ANALOGS OF THYMIDINE FOR EVALUATION AS ANTICANCER AND ANTIVIRAL AGENTS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 1/2, p. 41, doi. 10.1081/NCN-100001436
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Syntheses of 1-[(2-Hydroxyethoxy)methyl]- and 1-[(1,3-Dihydroxy-2-Propoxy)methyl]- Derivatives of 5-Substituted-2,4-difluorobenzene: Unnatural Acyclo Thymidine Mimics for Evaluation as Anticancer and Antiviral Agents.
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- Nucleosides, Nucleotides & Nucleic Acids, 2000, v. 19, n. 9, p. 1397, doi. 10.1080/15257770008033850
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Highly Stereoselective Synthesis and Biological Properties of Nucleoside Analogues Bearing a Spiro Inserted Oxirane Ring.
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- Nucleosides, Nucleotides & Nucleic Acids, 2000, v. 19, n. 4, p. 775, doi. 10.1080/15257770008035024
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Synthesis, spectroscopic characterization, in vitro cytotoxic and structure activity relationships of some mononuclear Ru(II) complexes.
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- Journal of Coordination Chemistry, 2013, v. 66, n. 5/6, p. 1031, doi. 10.1080/00958972.2013.773318
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Synthesis, spectroscopic characterization, antineoplastic, in vitro -cytotoxic, and antibacterial activities of mononuclear ruthenium(II) complexes.
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- Journal of Coordination Chemistry, 2012, v. 65, n. 5, p. 823, doi. 10.1080/00958972.2012.663082
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Synthesis, characterization, antitumor, and cytotoxic activity of mononuclear Ru(II) complexes.
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- Journal of Coordination Chemistry, 2010, v. 63, n. 24, p. 4332, doi. 10.1080/00958972.2010.534140
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Mycoplasma hyorhinis-encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs.
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- FEBS Open Bio, 2015, v. 5, p. 634, doi. 10.1016/j.fob.2015.07.007
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Bioreversible Protection of Nucleoside Diphosphates.
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- Angewandte Chemie International Edition, 2008, v. 47, n. 45, p. 8719, doi. 10.1002/anie.200803100
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Multiple Drug Resistance to Nucleoside Analogues and Nonnucleoside Reverse Transcriptase Inhibitors in an Efficiently Replicating Human Immunodeficiency Virus Type 1 Patient Strain.
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- Journal of Infectious Diseases, 1996, v. 174, n. 5, p. 962, doi. 10.1093/infdis/174.5.962
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Modification of the antibiotic olivomycin I at the 2′-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.
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- Journal of Antibiotics, 2009, v. 62, n. 2, p. 117, doi. 10.1038/ja.2009.3
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Modification of the antibiotic olivomycin I at the 2′-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.
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- Journal of Antibiotics, 2009, v. 62, n. 1, p. 37, doi. 10.1038/ja.2008.7
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