Works by Balusu, Sriram

Results: 23

Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54779-w

By:

Baligács, Nóra;
Albertini, Giulia;
Borrie, Sarah C.;
Serneels, Lutgarde;
Pridans, Clare;
Balusu, Sriram;
De Strooper, Bart

Publication type:

Article

Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 37, p. 12766, doi. 10.1523/JNEUROSCI.0006-15.2015

By:

Brkic, Marjana;
Balusu, Sriram;
Van Wonterghem, Elien;
Gorlé, Nina;
Benilova, Iryna;
Kremer, Anna;
Van Hove, Inge;
Moons, Lieve;
De Strooper, Bart;
Kanazir, Selma;
Libert, Claude;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

The inhibition of necroptosis prevents neuronal death in a mouse model of Alzheimer's disease pathology.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.087322

By:

Moonen, Sebastiaan;
Koper, Marta J;
Ronisz, Alicja;
Ospitalieri, Simona;
Vegh, Zsuzsanna;
T'Syen, Dries;
Rabe, Sabine;
Staufenbiel, Matthias;
De Strooper, Bart;
Balusu, Sriram;
Thal, Dietmar Rudolf

Publication type:

Article

Ponatinib and dabrafenib reduce the accumulation of necroptosis‐related proteins and neuronal loss in APP23xTAU58 mice.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.077757

By:

Koper, Marta J;
Moonen, Sebastiaan;
Ronisz, Alicja;
Ospitalieri, Simona;
Rabe, Sabine;
Staufenbiel, Matthias;
De Strooper, Bart;
Balusu, Sriram;
Thal, Dietmar Rudolf

Publication type:

Article

Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases.

Published in:

Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/620581

By:

Brkic, Marjana;
Balusu, Sriram;
Libert, Claude;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microglia.

Published in:

EMBO Molecular Medicine, 2024, v. 16, n. 12, p. 3113, doi. 10.1038/s44321-024-00162-7

By:

Preman, Pranav;
Moechars, Daan;
Fertan, Emre;
Wolfs, Leen;
Serneels, Lutgarde;
Shah, Disha;
Lamote, Jochen;
Poovathingal, Suresh;
Snellinx, An;
Mancuso, Renzo;
Balusu, Sriram;
Klenerman, David;
Arranz, Amaia M;
Fiers, Mark;
De Strooper, Bart

Publication type:

Article

Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 4, p. 1, doi. 10.15252/emmm.201708300

By:

Steeland, Sophie;
Gorlé, Nina;
Vandendriessche, Charysse;
Balusu, Sriram;
Brkic, Marjana;
Van Cauwenberghe, Caroline;
Van Imschoot, Griet;
Van Wonterghem, Elien;
De Rycke, Riet;
Kremer, Anneke;
Lippens, Saskia;
Stopa, Edward;
Johanson, Conrad E.;
Libert, Claude;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 10, p. 1162, doi. 10.15252/emmm.201606271

By:

Balusu, Sriram;
Van Wonterghem, Elien;
De Rycke, Riet;
Raemdonck, Koen;
Stremersch, Stephan;
Gevaert, Kris;
Brkic, Marjana;
Demeestere, Delphine;
Vanhooren, Valerie;
Hendrix, An;
Libert, Claude;
Vandenbroucke, Roosmarijn E

Publication type:

Article

Functional Genomic Analysis of Candida glabrata-Macrophage Interaction: Role of Chromatin Remodeling in Virulence.

Published in:

PLoS Pathogens, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.ppat.1002863

By:

Rai, Maruti Nandan;
Balusu, Sriram;
Gorityala, Neelima;
Dandu, Lakshmi;
Kaur, Rupinder

Publication type:

Article

The necroptosis cell death pathway drives neurodegeneration in Alzheimer's disease.

Published in:

Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02747-5

By:

Balusu, Sriram;
De Strooper, Bart

Publication type:

Article

Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer's disease.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 3, p. 463, doi. 10.1007/s00401-019-02103-y

By:

Koper, Marta J.;
Van Schoor, Evelien;
Ospitalieri, Simona;
Vandenberghe, Rik;
Vandenbulcke, Mathieu;
von Arnim, Christine A. F.;
Tousseyn, Thomas;
Balusu, Sriram;
De Strooper, Bart;
Thal, Dietmar Rudolf

Publication type:

Article

LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01432-6

By:

Koper, Marta J.;
Tomé, Sandra O.;
Gawor, Klara;
Belet, Annelies;
Van Schoor, Evelien;
Schaeverbeke, Jolien;
Vandenberghe, Rik;
Vandenbulcke, Mathieu;
Ghebremedhin, Estifanos;
Otto, Markus;
von Arnim, Christine A. F.;
Balusu, Sriram;
Blaschko, Matthew B.;
De Strooper, Bart;
Thal, Dietmar Rudolf

Publication type:

Article

Importance of extracellular vesicle secretion at the blood–cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01245-z

By:

Vandendriessche, Charysse;
Balusu, Sriram;
Van Cauwenberghe, Caroline;
Brkic, Marjana;
Pauwels, Marie;
Plehiers, Nele;
Bruggeman, Arnout;
Dujardin, Pieter;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Hendrix, An;
Baeke, Femke;
De Rycke, Riet;
Gevaert, Kris;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

An essential role for phosphatidylinositol 3-kinase in the inhibition of phagosomal maturation, intracellular survival and virulence in C andida glabrata.

Published in:

Cellular Microbiology, 2015, v. 17, n. 2, p. 269, doi. 10.1111/cmi.12364

By:

Rai, Maruti Nandan;
Sharma, Vandana;
Balusu, Sriram;
Kaur, Rupinder

Publication type:

Article

Inhibition of an Alzheimer's disease--associated form of necroptosis rescues neuronal death in mouse models.

Published in:

Science Translational Medicine, 2024, v. 16, n. 771, p. 1, doi. 10.1126/scitranslmed.adf5128

By:

Koper, Marta J.;
Moonen, Sebastiaan;
Ronisz, Alicja;
Ospitalieri, Simona;
Callaerts-Vegh, Zsuzsanna;
T'Syen, Dries;
Rabe, Sabine;
Staufenbiel, Matthias;
De Strooper, Bart;
Balusu, Sriram;
Thal, Dietmar Rudolf

Publication type:

Article

Xenografted human microglia in response to Alzheimer's disease Aβ pathology.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076968

By:

Martinez‐Muriana, Anna;
Mancuso, Renzo;
Fattorelli, Nicola;
Davis, Emma;
Wolfs, Leen;
Daele, Johanna Van Den;
Geric, Ivana;
Preman, Pranav;
Serneels, Lutgarde;
Poovathingal, Suresh Kumar;
Balusu, Sriram;
Verfaillie, Catherine;
Fiers, Mark;
De Strooper, Bart

Publication type:

Article

Systematic assessment of microRNA‐132 therapeutic targeting in Alzheimer's disease using iPSC‐derived neurons and microglia.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071458

By:

Penning, Amber;
Tosoni, Giorgia;
Walgrave, Hannah;
Snoeck, Sarah;
Balusu, Sriram;
Salta, Evgenia

Publication type:

Article

Systematic assessment of microRNA‐132 therapeutic targeting in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.060302

By:

Penning, Amber;
Tosoni, Giorgia;
Walgrave, Hannah;
Snoeck, Sarah;
Balusu, Sriram;
Salta, Evgenia

Publication type:

Article

CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 4, p. 1245, doi. 10.1002/alz.12760

By:

Guo, Wenting;
Wang, Haibo;
Kumar Tharkeshwar, Arun;
Couthouis, Julien;
Braems, Elke;
Masrori, Pegah;
Van Schoor, Evelien;
Fan, Yannan;
Ahuja, Karan;
Moisse, Matthieu;
Jacquemyn, Maarten;
Furtado Madeiro da Costa, Rodrigo;
Gajjar, Madhavsai;
Balusu, Sriram;
Tricot, Tine;
Fumagalli, Laura;
Hersmus, Nicole;
Janky, Rekin's;
Impens, Francis;
Vanden Berghe, Pieter

Publication type:

Article

Systematic evaluation of the therapeutic potential of microRNA‐132 in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053776

By:

Walgrave, Hannah;
Salta, Evgenia;
Snoeck, Sarah;
Mancuso, Renzo;
Balusu, Sriram;
Davie, Kristofer;
Impens, Francis;
de Strooper, Bart

Publication type:

Article

Induction of tau pathology, tangles and necroptosis in human neurons exposed to amyloid plaques in chimeric mouse brain.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.049953

By:

Balusu, Sriram;
De Strooper, Bart

Publication type:

Article

Alzheimer's disease‐related necroptotic pathology: An exclusive presence of the necrosome in granulovacuolar degeneration inclusions in human and transgenic mouse brains: Molecular and cell biology/neuronal cell death mechanisms (i.e. apoptosis).

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042460

By:

Koper, Marta J.;
Van Schoor, Evelien;
Ospitalieri, Simona;
Vandenberghe, Rik;
Vandenbulcke, Mathieu;
von Arnim, Christine;
Tousseyn, Thomas;
Reichwald, Julia;
Rabe, Sabine;
Staufenbiel, Matthias;
Balusu, Sriram;
De Strooper, Bart;
Thal, Dietmar Rudolf

Publication type:

Article

P1‐180: AN ULTRASTRUCTURAL STUDY OF THE MORPHOLOGICAL ALTERATIONS OF THE CHOROID PLEXUS EPITHELIUM IN ALZHEIMER'S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P347, doi. 10.1016/j.jalz.2018.06.184

By:

Van Cauwenberghe, Caroline;
Vandendriessche, Charysse;
Balusu, Sriram;
Kremer, Anneke;
De Rycke, Riet;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Lippens, Saskia;
Vandenbroucke, Roosmarijn E.

Publication type:

Article