Works by Bainbridge, James

Results: 54

Retinal dystrophies and gene therapy.

Published in:

2012

By:

Sundaram V;
Moore AT;
Ali RR;
Bainbridge JW;
Sundaram, Venki;
Moore, Anthony T;
Ali, Robin R;
Bainbridge, James W

Publication type:

journal article

Educational paper.

Published in:

European Journal of Pediatrics, 2012, v. 171, n. 5, p. 757, doi. 10.1007/s00431-011-1615-2

By:

Sundaram, Venki;
Moore, Anthony;
Ali, Robin;
Bainbridge, James

Publication type:

Article

Human genome map beginning to pay dividends in ophthalmology.

Published in:

Ocular Surgery News, 2009, v. 27, n. 6, p. 1

By:

Bainbridge, James W. B.;
Campochiaro, Peter A.;
Chin, Hemin R.;
Moroi, Sayoko E.;
Stout, J. Timothy

Publication type:

Article

Correction: The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice.

Published in:

2023

By:

Georgiadis, Anastasios;
Tschernutter, Marion;
Bainbridge, James W. B.;
Balaggan, Kamaljit S.;
Mowat, Freya;
West, Emma L.;
Munro, Peter M. G.;
Thrasher, Adrian J.;
Matter, Karl;
Balda, Maria S.;
Ali, Robin R.

Publication type:

Correction Notice

Cover Image, Volume 69, Issue 9.

Published in:

Glia (0894-1491), 2021, v. 69, n. 9, p. C1, doi. 10.1002/glia.24057

By:

Hippert, Claire;
Graca, Anna B.;
Basche, Mark;
Kalargyrou, Aikaterini A.;
Georgiadis, Anastasios;
Ribeiro, Joana;
Matsuyama, Ayako;
Aghaizu, Nozie;
Bainbridge, James W.;
Smith, Alexander J.;
Ali, Robin R.;
Pearson, Rachael A.

Publication type:

Article

RNAi‐mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration.

Published in:

Glia (0894-1491), 2021, v. 69, n. 9, p. 2272, doi. 10.1002/glia.24034

By:

Hippert, Claire;
Graca, Anna B.;
Basche, Mark;
Kalargyrou, Aikaterini A.;
Georgiadis, Anastasios;
Ribeiro, Joana;
Matsuyama, Ayako;
Aghaizu, Nozie;
Bainbridge, James W.;
Smith, Alexander J.;
Ali, Robin R.;
Pearson, Rachael A.

Publication type:

Article

Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice.

Published in:

Journal of Gene Medicine, 2009, v. 11, n. 6, p. 486, doi. 10.1002/jgm.1327

By:

Barker, Susie E.;
Broderick, Cathryn A.;
Robbie, Scott J.;
Duran, Yanai;
Natkunarajah, Mythili;
Buch, Prateek;
Balaggan, Kamaljit S.;
MacLaren, Robert E.;
Bainbridge, James W. B.;
Smith, Alexander J.;
Ali, Robin R.

Publication type:

Article

Long-term evaluation of retinal function in Prph2Rd2/Rd2 mice following AAV-mediated gene replacement therapy.

Published in:

Journal of Gene Medicine, 2003, v. 5, n. 9, p. 757

By:

Frank C. Schlichtenbrede;
Lyndon da Cruz;
Clare Stephens;
Alexander J. Smith;
Anastasios Georgiadis;
Adrian J. Thrasher;
James W. B. Bainbridge;
Mathias W. Seeliger

Publication type:

Article

Clinical and functional analyses of AIPL1 variants reveal mechanisms of pathogenicity linked to different forms of retinal degeneration.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-74516-9

By:

Sacristan-Reviriego, Almudena;
Le, Hoang Mai;
Georgiou, Michalis;
Meunier, Isabelle;
Bocquet, Beatrice;
Roux, Anne-Françoise;
Prodromou, Chrisostomos;
Bainbridge, James;
Michaelides, Michel;
van der Spuy, Jacqueline

Publication type:

Article

Gene therapy for Leber congenital amaurosis.

Published in:

Expert Review of Ophthalmology, 2018, v. 13, n. 1, p. 11, doi. 10.1080/17469899.2018.1429916

By:

Kumaran, Neruban;
Smith, Alexander J.;
Michaelides, Michel;
Ali, Robin;
Bainbridge, James

Publication type:

Article

Retinal cell transplantation: prospects for the future.

Published in:

Expert Review of Ophthalmology, 2012, v. 7, n. 2, p. 99, doi. 10.1586/eop.12.9

By:

Ali, Robin R.;
Bainbridge, James W. B.

Publication type:

Article

Gene therapy for inherited childhood blindness shows promise.

Published in:

2008

By:

Bainbridge, James;
Ali, Robin

Publication type:

Editorial

The macrophage is key to choroidal neovascularization in age-related macular degeneration.

Published in:

Expert Review of Ophthalmology, 2007, v. 2, n. 6, p. 981, doi. 10.1586/17469899.2.6.981

By:

Bainbridge, James

Publication type:

Article

Gene therapy clinical trials for inherited eye disease.

Published in:

2007

By:

Bainbridge, James

Publication type:

Editorial

Corrigendum: LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.

Published in:

Nature, 2013, v. 501, n. 7468, p. 578, doi. 10.1038/nature12641

By:

Wang, Xiaomeng;
Abraham, Sabu;
McKenzie, Jenny A. G.;
Jeffs, Natasha;
Swire, Matthew;
Tripathi, Vineeta B.;
Luhmann, Ulrich F. O.;
Lange, Clemens A. K.;
Zhai, Zhenhua;
Arthur, Helen M.;
Bainbridge, James W. B.;
Moss, Stephen E.;
Greenwood, John

Publication type:

Article

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.

Published in:

Nature, 2013, v. 499, n. 7458, p. 306, doi. 10.1038/nature12345

By:

Wang, Xiaomeng;
Abraham, Sabu;
McKenzie, Jenny A. G.;
Jeffs, Natasha;
Swire, Matthew;
Tripathi, Vineeta B.;
Luhmann, Ulrich F. O.;
Lange, Clemens A. K.;
Zhai, Zhenhua;
Arthur, Helen M.;
Bainbridge, James W. B.;
Moss, Stephen E.;
Greenwood, John

Publication type:

Article

Transcriptional Profiling Uncovers Human Hyalocytes as a Unique Innate Immune Cell Population.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.567274

By:

Boneva, Stefaniya Konstantinova;
Wolf, Julian;
Rosmus, Dennis-Dominik;
Schlecht, Anja;
Prinz, Gabriele;
Laich, Yannik;
Boeck, Myriam;
Zhang, Peipei;
Hilgendorf, Ingo;
Stahl, Andreas;
Reinhard, Thomas;
Bainbridge, James;
Schlunck, Günther;
Agostini, Hansjürgen;
Wieghofer, Peter;
Lange, Clemens A. K.

Publication type:

Article

Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy.

Published in:

Nature Genetics, 2000, v. 25, n. 3, p. 306, doi. 10.1038/77068

By:

Ali, Robin R.;
Sarra, Gian-Marco;
Stephens, Clare;
Alwis, Mahesh de;
Bainbridge, James W.B.;
Munro, Peter M.;
Fauser, Sascha;
Reichel, Martin B.;
Kinnon, Christine;
Hunt, David M.;
Bhattacharya, Shomi S.;
Thrasher, Adrian J.

Publication type:

Article

Nature of subretinal fluid in patients undergoing vitrectomy for macular hole: a cytopathological and optical coherence tomography study.

Published in:

Clinical & Experimental Ophthalmology, 2008, v. 36, n. 9, p. 812, doi. 10.1111/j.1442-9071.2008.01901.x

By:

Herbert, Edward N.;
Sheth, Hiten G.;
Wickremasinghe, Sanjeewa;
Luthert, Philip J.;
Bainbridge, James;
Gregor, Zdenek J.

Publication type:

Article

CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep03072

By:

Shintaro Horie;
Robbie, Scott J.;
Jian Liu;
Wei-Kang Wu;
Ali, Robin R.;
Bainbridge, James W.;
Nicholson, Lindsay B.;
Mochizuki, Manabu;
Dick, Andrew D.;
Copland, David A.

Publication type:

Article

PIMS (Positioning In Macular hole Surgery) trial – a multicentre interventional comparative randomised controlled clinical trial comparing face-down positioning, with an inactive face-forward position on the outcome of surgery for large macular holes: study protocol for a randomised controlled trial.

Published in:

Trials, 2015, v. 16, n. 1, p. 527, doi. 10.1186/s13063-015-1048-8

By:

Pasu, Saruban;
Bunce, Catey;
Hooper, Richard;
Thomson, Ann;
Bainbridge, James

Publication type:

Article

PIMS (Positioning In Macular hole Surgery) trial - a multicentre interventional comparative randomised controlled clinical trial comparing face-down positioning, with an inactive face-forward position on the outcome of surgery for large macular holes: study protocol for a randomised controlled trial.

Published in:

2015

By:

Pasu, Saruban;
Bunce, Catey;
Hooper, Richard;
Thomson, Ann;
Bainbridge, James

Publication type:

journal article

Retinal gene therapy.

Published in:

British Medical Bulletin, 2018, v. 126, n. 1, p. 13, doi. 10.1093/bmb/ldy005

By:

Kumaran, Neruban;
Michaelides, Michel;
Smith, Alexander J.;
Ali, Robin R.;
Bainbridge, James W. B.

Publication type:

Article

Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179759

By:

Villacampa, Pilar;
Menger, Katja E.;
Abelleira, Laura;
Ribeiro, Joana;
Duran, Yanai;
Smith, Alexander J.;
Ali, Robin R.;
Luhmann, Ulrich F.;
Bainbridge, James W. B.

Publication type:

Article

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina.

Published in:

Nature Biotechnology, 2013, v. 31, n. 8, p. 741, doi. 10.1038/nbt.2643

By:

Gonzalez-Cordero, Anai;
West, Emma L;
Pearson, Rachael A;
Duran, Yanai;
Carvalho, Livia S;
Chu, Colin J;
Naeem, Arifa;
Blackford, Samuel J I;
Georgiadis, Anastasios;
Lakowski, Jorn;
Hubank, Mike;
Smith, Alexander J;
Bainbridge, James W B;
Sowden, Jane C;
Ali, Robin R

Publication type:

Article

Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina.

Published in:

Clinical Science, 2017, v. 131, n. 12, p. 1225, doi. 10.1042/CS20170102

By:

Ved, Nikita;
Hulse, Richard P.;
Bestall, Samuel M.;
Donaldson, Lucy F.;
Bainbridge, James W.;
Bates, David O.

Publication type:

Article

Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis.

Published in:

Journal of Cell Biology, 2022, v. 221, n. 11, p. 1, doi. 10.1083/jcb.202012042

By:

Zihni, Ceniz;
Georgiadis, Anastasios;
Ramsden, Conor M.;
Sanchez-Heras, Elena;
Haas, Alexis J.;
Nommiste, Britta;
Semenyuk, Olha;
Bainbridge, James W. B.;
Coffey, Peter J.;
Smith, Alexander J.;
Ali, Robin R.;
Balda, Maria S.;
Matter, Karl

Publication type:

Article

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179.

Published in:

Nature Communications, 2015, v. 6, n. 1, p. 6006, doi. 10.1038/ncomms7006

By:

Nishiguchi, Koji M.;
Carvalho, Livia S.;
Rizzi, Matteo;
Powell, Kate;
Holthaus, Sophia-Martha kleine;
Azam, Selina A.;
Duran, Yanai;
Ribeiro, Joana;
Luhmann, Ulrich F. O.;
Bainbridge, James W. B.;
Smith, Alexander J.;
Ali, Robin R.

Publication type:

Article

Positioning In Macular hole Surgery (PIMS): statistical analysis plan for a randomised controlled trial.

Published in:

2017

By:

Bell, Lauren;
Hooper, Richard;
Bunce, Catey;
Pasu, Saruban;
Bainbridge, James

Publication type:

journal article

Oxygen Sensing in Retinal Health and Disease.

Published in:

Ophthalmologica, 2012, v. 227, n. 3, p. 115, doi. 10.1159/000331418

By:

Lange, Clemens A.K.;
Bainbridge, James W.B.

Publication type:

Article

Facedown Positioning Following Surgery for Large Full-Thickness Macular Hole: A Multicenter Randomized Clinical Trial.

Published in:

2020

By:

Pasu, Saruban;
Bell, Lauren;
Zenasni, Zohra;
Lanz, Doris;
Simmonds, Irene A;
Thompson, Ann;
Yorston, David;
Laidlaw, D. Alistair H.;
Bunce, Catey;
Hooper, Richard;
Bainbridge, James W. B.;
Positioning In Macular Hole Surgery (PIMS) Study Group

Publication type:

journal article

Retinal Nonperfusion Characteristics on Ultra-Widefield Angiography in Eyes With Severe Nonproliferative Diabetic Retinopathy and Proliferative Diabetic Retinopathy.

Published in:

2019

By:

Nicholson, Luke;
Ramu, Jayashree;
Chan, Errol W.;
Bainbridge, James W.;
Hykin, Philip G.;
Talks, Stephen J.;
Sivaprasad, Sobha

Publication type:

journal article

Retinal Oximetry Differences Between Optic Disc Collateral Vessels and New Vessels.

Published in:

2017

By:

Nicholson, Luke;
Sivapathasuntharam, Chrishne;
Zola, Marta;
Hykin, Philip;
Bainbridge, James W.;
Sivaprasad, Sobha

Publication type:

journal article

Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye.

Published in:

Scientific Reports, 2017, p. 40830, doi. 10.1038/srep40830

By:

Gardner, Peter J.;
Liyanage, Sidath E.;
Cristante, Enrico;
Sampson, Robert D.;
Dick, Andrew D.;
Ali, Robin R.;
Bainbridge, James W.

Publication type:

Article

The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 22, p. 4465, doi. 10.1093/hmg/ddx334

By:

Sacristan-Reviriego, Almudena;
Bellingham, James;
Prodromou, Chrisostomos;
Kumaran, Neruban;
Bainbridge, James;
Michaelides, Michel;
van der Spuy, Jacqueline

Publication type:

Article

The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors

Published in:

Human Molecular Genetics, 2015, v. 24, n. 1, p. 128, doi. 10.1093/hmg/ddu424

By:

Luhmann, Ulrich F.O.;
Carvalho, Livia S.;
kleine Holthaus, Sophia-Martha;
Cowing, Jill A.;
Greenaway, Simon;
Chu, Colin J.;
Herrmann, Philipp;
Smith, Alexander J.;
Munro, Peter M.G.;
Potter, Paul;
Bainbridge, James W.B.;
Ali, Robin R.

Publication type:

Article

Hsp90 inhibition protects against inherited retinal degeneration.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 8, p. 2164

By:

Aguilà, Mònica;
Bevilacqua, Dalila;
McCulley, Caroline;
Schwarz, Nele;
Athanasiou, Dimitra;
Kanuga, Naheed;
Novoselov, Sergey S.;
Lange, Clemens A.K.;
Ali, Robin R.;
Bainbridge, James W.;
Gias, Carlos;
Coffey, Peter J.;
Garriga, Pere;
Cheetham, Michael E.

Publication type:

Article

Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 16, p. 3161, doi. 10.1093/hmg/ddr218

By:

Carvalho, Livia S.;
Xu, Jianhua;
Pearson, Rachael A.;
Smith, Alexander J.;
Bainbridge, James W.;
Morris, Lynsie M.;
Fliesler, Steven J.;
Ding, Xi-Qin;
Ali, Robin R.

Publication type:

Article

Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors.

Published in:

Human Molecular Genetics, 2010, v. 19, n. 4, p. 735, doi. 10.1093/hmg/ddp540

By:

Tan, Mei Hong;
Smith, Alexander J.;
Pawlyk, Basil;
Xu, Xiaoyun;
Liu, Xiaoqing;
Bainbridge, James B.;
Basche, Mark;
McIntosh, Jenny;
Tran, Hoai Viet;
Nathwani, Amit;
Li, Tiansen;
Ali, Robin R.

Publication type:

Article

Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 12, p. 2099, doi. 10.1093/hmg/ddp133

By:

Tan, Mei Hong;
Smith, Alexander J.;
Pawlyk, Basil;
Xu, Xiaoyun;
Liu, Xiaoqing;
Bainbridge, James B.;
Basche, Mark;
McIntosh, Jenny;
Tran, Hoai Viet;
Nathwani, Amit;
Li, Tiansen;
Ali, Robin R.

Publication type:

Article

Assessment and In Vivo Scoring of Murine Experimental Autoimmune Uveoretinitis Using Optical Coherence Tomography

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063002

By:

Chu, Colin J.;
Herrmann, Philipp;
Carvalho, Livia S.;
Liyanage, Sidath E.;
Bainbridge, James W. B.;
Ali, Robin R.;
Dick, Andrew D.;
Luhmann, Ulrich F. O.

Publication type:

Article

Differential Modulation of Retinal Degeneration by Ccl2 and Cx3cr1 Chemokine Signalling.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035551

By:

Luhmann, Ulrich F. O.;
Lange, Clemens A.;
Robbie, Scott;
Munro, Peter M. G.;
Cowing, Jill A.;
Armer, Hannah E. J.;
Luong, Vy;
Carvalho, Livia S.;
MacLaren, Robert E.;
Fitzke, Frederick W.;
Bainbridge, James W. B.;
Ali, Robin R.

Publication type:

Article

The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015730

By:

Georgiadis, Anastasios;
Tschernutter, Marion;
Bainbridge, James W. B.;
Balaggan, Kamaljit S.;
Mowat, Freya;
West, Emma L.;
Munro, Peter M. G.;
Thrasher, Adrian J.;
Matter, Karl;
Balda, Maria S.;
Ali, Robin R.

Publication type:

Article

HIF-1alpha and HIF-2alpha Are Differentially Activated in Distinct Cell Populations in Retinal Ischaemia.

Published in:

PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0011103

By:

Mowat, Freya M.;
Luhmann, Ulrich F. O.;
Smith, Alexander J.;
Lange, Clemens;
Duran, Yanai;
Harten, Sarah;
Shukla, Deepa;
Maxwell, Patrick H.;
Ali, Robin R.;
Bainbridge, James W. B.

Publication type:

Article

A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs.

Published in:

Cells (2073-4409), 2021, v. 10, n. 1, p. 115, doi. 10.3390/cells10010115

By:

Annear, Matthew J;
Mowat, Freya M;
Occelli, Laurence M;
Smith, Alexander J;
Curran, Paul G;
Bainbridge, James W;
Ali, Robin R;
Petersen-Jones, Simon M

Publication type:

Article

Achromatopsia: clinical features, molecular genetics, animal models and therapeutic options.

Published in:

Ophthalmic Genetics, 2018, v. 39, n. 2, p. 149, doi. 10.1080/13816810.2017.1418389

By:

Hirji, Nashila;
Aboshiha, Jonathan;
Georgiou, Michalis;
Bainbridge, James;
Michaelides, Michel

Publication type:

Article

Refractory Diabetic Macular Edema.

Published in:

2010

By:

Bainbridge, James

Publication type:

Editorial

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell-Derived Self-Forming Retina.

Published in:

Stem Cells, 2015, v. 33, n. 8, p. 2469, doi. 10.1002/stem.2051

By:

Naeem, Arifa;
Welby, Emily;
Sowden, Jane C.;
Gonzalez-Cordero, Anai;
West, Emma L.;
Bainbridge, James W. B.;
Lakowski, Jorn;
Pearson, Rachael A.;
Han, Ya-Ting;
Blackford, Samuel J. I.;
Ali, Robin R.

Publication type:

Article

B.Â Lorenz and A.T.Â Moore (eds): Pediatric ophthalmology, neuro-ophthalmology, genetics. (The Essentials in Ophthalmology Series: G.K. Krieglstein and R.M. Weinreb, series eds).

Published in:

Graefe's Archive of Clinical & Experimental Ophthalmology, 2007, v. 245, n. 5, p. 763, doi. 10.1007/s00417-006-0427-y

By:

James Bainbridge

Publication type:

Article

Gene Transfer of An Engineered Zinc Finger Protein Enhances the Anti-angiogenic Defense System.

Published in:

Molecular Therapy, 2007, v. 15, n. 11, p. 1917, doi. 10.1038/sj.mt.6300280

By:

Yokoi, Katsutoshi;
Zhang, Huanda Steve;
Shu Kachi;
Balaggan, Kamaljit S.;
Qi Yu;
Guschin, Dmitry;
Kunis, Mike;
Surosky, Richard;
Africa, Liza M.;
Bainbridge, James W.;
Spratt, Sharon Kaye;
Gregory, Philip D.;
Ali, Robin R.;
Campochiaro, Peter A.

Publication type:

Article