Works by Bacman, Sandra

Results: 14

Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 13, p. 4218, doi. 10.1093/nar/gkp348

By:

Bacman, Sandra R.;
Williams, Sion L.;
Moraes, Carlos T.

Publication type:

Article

The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04895-1

By:

Nissanka, Nadee;
Bacman, Sandra R.;
Plastini, Melanie J.;
Moraes, Carlos T.

Publication type:

Article

Correcting a pathogenic mitochondrial DNA mutation by base editing in mice.

Published in:

Science Translational Medicine, 2025, v. 17, n. 783, p. 1, doi. 10.1126/scitranslmed.adr0792

By:

Barrera-Paez, Jose D.;
Bacman, Sandra R.;
Balla, Till;
Van Booven, Derek;
Gannamedi, Durga P.;
Stewart, James B.;
Mok, Beverly;
Liu, David R.;
Lombard, David B.;
Griswold, Anthony J.;
Nedialkova, Danny D.;
Moraes, Carlos T.

Publication type:

Article

mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 9, p. 1, doi. 10.15252/emmm.201708084

By:

Pereira, Claudia V.;
Bacman, Sandra R.;
Arguello, Tania;
Zekonyte, Ugne;
Williams, Sion L.;
Edgell, David R.;
Moraes, Carlos T.

Publication type:

Article

Cytochrome c Association with the Inner Mitochondrial Membrane Is Impaired in the CNS of G93A-SOD1 Mice.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 1, p. 164, doi. 10.1523/JNEUROSCI.3829-04.2005

By:

Kirkinezos, Ilias G.;
Bacman, Sandra R.;
Hernandez, Dayami;
Oca-Cossio, Jose;
Arias, Laura J.;
Perez-Pinzon, Miguel A.;
Bradley, Walter G.;
Moraes, Carlos T.

Publication type:

Article

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs.

Published in:

Nature Medicine, 2013, v. 19, n. 9, p. 1111, doi. 10.1038/nm.3261

By:

Bacman, Sandra R;
Williams, Siôn L;
Pinto, Milena;
Peralta, Susana;
Moraes, Carlos T

Publication type:

Article

Mitochondrial involvement in amyotrophic lateral sclerosis.

Published in:

Molecular Neurobiology, 2006, v. 33, n. 2, p. 113, doi. 10.1385/MN:33:2:113

By:

Bacman, Sandra;
Bradley, Walter;
Moraes, Carlos

Publication type:

Article

Restoration of defective oxidative phosphorylation to a subset of neurons prevents mitochondrial encephalopathy.

Published in:

EMBO Molecular Medicine, 2024, v. 16, n. 9, p. 2210, doi. 10.1038/s44321-024-00111-4

By:

Walker, Brittni R;
Theard, Lise-Michelle;
Pinto, Milena;
Rodriguez-Silva, Monica;
Bacman, Sandra R;
Moraes, Carlos T

Publication type:

Article

High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.

Published in:

EMBO Molecular Medicine, 2024, v. 16, n. 6, p. 1352, doi. 10.1038/s44321-024-00067-5

By:

Southwell, Nneka;
Manzo, Onorina;
Bacman, Sandra;
Zhao, Dazhi;
Sayles, Nicole M;
Dash, Jalia;
Fujita, Keigo;
D'Aurelio, Marilena;
Di Lorenzo, Annarita;
Manfredi, Giovanni;
Kawamata, Hibiki

Publication type:

Article

Myopathy reversion in mice after restauration of mitochondrial complex I.

Published in:

EMBO Molecular Medicine, 2020, v. 12, n. 2, p. N.PAG, doi. 10.15252/emmm.201910674

By:

Pereira, Claudia V;
Peralta, Susana;
Arguello, Tania;
Bacman, Sandra R;
Diaz, Francisca;
Moraes, Carlos T

Publication type:

Article

Human primary Sjögren's syndrome autoantibodies as mediators of nitric oxide release coupled to lacrimal gland muscarinic acetylcholine receptors.

Published in:

Current Eye Research, 1998, v. 17, n. 12, p. 1135, doi. 10.1076/ceyr.17.12.1135.5124

By:

Bacman, Sandra R.;
Berra, Alejandro;
Sterin-Borda, Leonor;
Borda, Enri E.S.;
Borda, Enri S.

Publication type:

Article

MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1592, doi. 10.1038/mt.2015.126

By:

Hashimoto, Masami;
Bacman, Sandra R;
Peralta, Susana;
Falk, Marni J;
Chomyn, Anne;
Chan, David C;
Williams, Sion L;
Moraes, Carlos T

Publication type:

Article

Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23561-7

By:

Zekonyte, Ugne;
Bacman, Sandra R.;
Smith, Jeff;
Shoop, Wendy;
Pereira, Claudia V.;
Tomberlin, Ginger;
Stewart, James;
Jantz, Derek;
Moraes, Carlos T.

Publication type:

Article

NEK10 kinase ablation affects mitochondrial morphology, function and protein phosphorylation status.

Published in:

Proteome Science, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12953-024-00234-z

By:

de Oliveira, Andressa Peres;
Navarro, Claudia D. C.;
Dias, Pedro Rafael F.;
Arguello, Tania;
Walker, Brittni R.;
Bacman, Sandra R.;
Sousa, Lizandra Maia;
Castilho, Roger F.;
Consonni, Sílvio R.;
Moraes, Carlos T.;
Kobarg, Jörg

Publication type:

Article