Works matching AU Back, David J.

Results: 53

Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP.

Published in:

Transplant International, 2008, v. 21, n. 11, p. 1066, doi. 10.1111/j.1432-2277.2008.00739.x

By:

Sankatsing, Sanjay U. C.;
Prins, Jan M.;
Yong, Si-La L.;
Roelofsen, Jeroen;
van Kuilenburg, André B. P.;
Kewn, Steve;
Back, David J.;
Bemelman, Frederike J.;
ten Berge, Ineke J. M.

Publication type:

Article

Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug--drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2018, v. 73, n. 4, p. 1004, doi. 10.1093/jac/dkx515

By:

Roberts, Owain;
Rajoli, Rajith K. R.;
Back, David J.;
Owen, Andrew;
Darin, Kristin M.;
Fletcher, Courtney V.;
Lamorde, Mohammed;
Scarsi, Kimberly K.;
Siccardi, Marco

Publication type:

Article

Steady-state pharmacokinetics of rilpivirine under different meal conditions in HIV-1-infected Ugandan adults.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2015, v. 70, n. 5, p. 1482, doi. 10.1093/jac/dku575

By:

Lamorde, Mohammed;
Walimbwa, Stephen;
Byakika-Kibwika, Pauline;
Katwere, Michael;
Mukisa, Lillian;
Sempa, Joseph B.;
Else, Laura;
Back, David J.;
Khoo, Saye H.;
Merry, Concepta

Publication type:

Article

Effect of intermittent rifampicin on the pharmacokinetics and safety of raltegravir.

Published in:

2015

By:

Reynolds, Helen E;
Chrdle, Ales;
Egan, Deirdre;
Chaponda, Mas;
Else, Laura;
Chiong, Justin;
Back, David J;
Khoo, Saye H

Publication type:

journal article

Predicting intestinal absorption of raltegravir using a population-based ADME simulation.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 7, p. 1627, doi. 10.1093/jac/dkt084

By:

Moss, Darren M.;
Siccardi, Marco;
Back, David J.;
Owen, Andrew

Publication type:

Article

Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2011, v. 66, n. 6, p. 1332, doi. 10.1093/jac/dkr087

By:

Schipani, Alessandro;
Wyen, Christoph;
Mahungu, Tabitha;
Hendra, Heidy;
Egan, Deirdre;
Siccardi, Marco;
Davies, Gerry;
Saye Khoo;
Fätkenheuer, Gerd;
Youle, Michael;
Rockstroh, Jürgen;
Brockmeyer, Norbert H.;
Johnson, Margaret A.;
Owen, Andrew;
Back, David J.

Publication type:

Article

Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2010, v. 65, n. 5, p. 906, doi. 10.1093/jac/dkq082

By:

Janneh, Omar;
Bray, Patrick G.;
Jones, Elizabeth;
Wyen, Christoph;
Chiba, Peter;
Back, David J.;
Khoo, Saye H.

Publication type:

Article

Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2009, v. 64, n. 5, p. 1002, doi. 10.1093/jac/dkp335

By:

Janneh, Omar;
Chandler, Becky;
Hartkoorn, Ruben;
Wai San Kwan;
Jenkinson, Claire;
Evans, Sorcha;
Back, David J.;
Owen, Andrew;
Khoo, Saye H.

Publication type:

Article

Population pharmacokinetics of ritonavir-boosted saquinavir regimens in HIV-infected individuals.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2008, v. 62, n. 6, p. 1344, doi. 10.1093/jac/dkn399

By:

Laura Dickinson;
Marta Boffito;
David J. Back;
Saye H. Khoo;
Anton L. Pozniak;
Peter Mugyenyi;
Concepta Merry;
Reshma Saskia Autar;
David M. Burger;
Leon J. Aarons

Publication type:

Article

Pharmacokinetic analysis to assess forgiveness of boosted saquinavir regimens for missed or late dosing.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2008, v. 62, n. 1, p. 161, doi. 10.1093/jac/dkn187

By:

Laura Dickinson;
Marta Boffito;
Saye H. Khoo;
Malte Schutz;
Leon J. Aarons;
Anton L. Pozniak;
David J. Back

Publication type:

Article

Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients.

Published in:

2008

By:

Wyen, Christoph;
Hendra, Heidy;
Vogel, Martin;
Hoffmann, Christian;
Knechten, Heribert;
Brockmeyer, Norbert H;
Bogner, Johannes R;
Rockstroh, Jürgen;
Esser, Stefan;
Jaeger, Hans;
Harrer, Thomas;
Mauss, Stefan;
van Lunzen, Jan;
Skoetz, Nicole;
Jetter, Alexander;
Groneuer, Christiane;
Fätkenheuer, Gerd;
Khoo, Saye H;
Egan, Deirdre;
Back, David J

Publication type:

journal article

Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2008, v. 61, n. 4, p. 914

By:

Christoph Wyen;
Heidy Hendra;
Martin Vogel;
Christian Hoffmann;
Heribert Knechten;
Norbert H. Brockmeyer;
Johannes R. Bogner;
Jürgen Rockstroh;
Stefan Esser;
Hans Jaeger;
Thomas Harrer;
Stefan Mauss;
Jan van Lunzen;
Nicole Skoetz;
Alexander Jetter;
Christiane Groneuer;
Gerd Fätkenheuer;
Saye H. Khoo;
Deirdre Egan;
David J. Back

Publication type:

Article

Factors impacting the expression of membrane-bound proteins in lymphocytes from HIV-positive subjects.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2007, v. 60, n. 3, p. 685, doi. 10.1093/jac/dkm230

By:

Becky Chandler;
Maria Detsika;
Saye H. Khoo;
Jill Williams;
David J. Back;
Andrew Owen

Publication type:

Article

Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 56, n. 4, p. 738, doi. 10.1093/jac/dki308

By:

Lisa M. Almond;
Patrick G. Hoggard;
Damitha Edirisinghe;
Saye H. Khoo;
David J. Back

Publication type:

Article

Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2004, v. 54, n. 2, p. 498, doi. 10.1093/jac/dkh357

By:

Adil Isaac;
Stephen Taylor;
Patricia Cane;
Erasmus Smit;
Sarah E. Gibbons;
David J. White;
Susan M. Drake;
Saye Khoo;
David J. Back

Publication type:

Article

Pharmacokinetics of saquinavir co-administered with cimetidine.

Published in:

2002

By:

Boffito, Marta;
Carriero, Pierluigi;
Trentini, Laura;
Raiteri, Riccardo;
Bonora, Stefano;
Sinicco, Alessandro;
Reynolds, Helen E.;
Hoggard, Patrick G.;
Back, David J.;
Perri, Giovanni Di;
Di Perri, Giovanni

Publication type:

journal article

Erratum.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2002, v. 49, n. 1, p. 227

By:

Taylor, Stephen;
Back, David J.;
Drake, Susan M.;
Workman, Judith;
Reynolds, Helen;
Gibbons, Sara E.;
White, David J.;
Pillay, Deenan

Publication type:

Article

Antiretroviral drug concentrations in semen of HIV-infected men: differential penetration of indinavir, ritonavir and saquinavir.

Published in:

2001

By:

Taylor, Stephen;
Back, David J.;
Drake, Susan M.;
Workman, Judith;
Reynolds, Helen;
Gibbons, Sara E.;
White, David J.;
Pillay, Deenan;
Taylor, S;
Back, D J;
Drake, S M;
Workman, J;
Reynolds, H;
Gibbons, S E;
White, D J;
Pillay, D

Publication type:

journal article

Widespread use of herbal medicines by people living with human immunodeficiency virus and contamination of herbal medicines with antiretrovirals in Nigeria.

Published in:

International Journal of STD & AIDS, 2019, v. 30, n. 4, p. 371, doi. 10.1177/0956462418809749

By:

Gini, J.;
Amara, A.;
Penchala, Sujan D.;
Back, David J.;
Else, L.;
Egan, D.;
Chiong, J.;
Harri, Bala I.;
Kabilis, Elkanah D.;
Pama, Paul P.;
Stephen, M.;
Khoo, Saye H.

Publication type:

Article

Widespread use of herbal medicines by people living with human immunodeficiency virus and contamination of herbal medicines with antiretrovirals in Nigeria.

Published in:

2019

By:

Gini, J;
Amara, A;
Penchala, Sujan D;
Back, David J;
Else, L;
Egan, D;
Chiong, J;
Harri, Bala I;
Kabilis, Elkanah D;
Pama, Paul P;
Stephen, M;
Khoo, Saye H

Publication type:

journal article

Telmisartan reverses antiretroviral-induced adipocyte toxicity and insulin resistance in vitro.

Published in:

Diabetes & Vascular Disease Research, 2018, v. 15, n. 3, p. 233, doi. 10.1177/1479164118757924

By:

Pushpakom, Sudeep P.;
Adaikalakoteswari, Antonysunil;
Owen, Andrew;
Back, David J.;
Tripathi, Gyanendra;
Kumar, Sudhesh;
McTernan, Philip;
Pirmohamed, Munir

Publication type:

Article

The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes.

Published in:

2010

By:

Janneh, Omar;
Owen, Andrew;
Bray, Patrick G.;
Back, David J.;
Pirmohamed, Munir

Publication type:

journal article

Population pharmacokinetics of efavirenz in an unselected cohort of HIV-1-infected individuals.

Published in:

2006

By:

Back, David J.;
Owen, Andrew;
Saye H. Khoo;
Khoo, Saye H

Publication type:

commentary

Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and on intracellular nucleoside triphosphate pools.

Published in:

2004

By:

Sankatsing, Sanjay U. C.;
Hoggard, Patrick G.;
Huitema, Alwin D. R.;
Sparidans, RolfW.;
Kewn, Stephen;
Crommentuyn, Kristel M. L.;
Lange, Joep M. A.;
Beijnen, Jos H.;
Back, David J.;
Prins, Jan M.;
Sparidans, Rolf W

Publication type:

journal article

Unintended Pregnancies Observed With Combined Use of the Levonorgestrel Contraceptive Implant and Efavirenz-based Antiretroviral Therapy: A Three-Arm Pharmacokinetic Evaluation Over 48 Weeks.

Published in:

Clinical Infectious Diseases, 2016, v. 62, n. 6, p. 675, doi. 10.1093/cid/civ1001

By:

Scarsi, Kimberly K.;
Darin, Kristin M.;
Merry, Concepta;
Cohn, Susan E.;
Nakalema, Shadia;
Byakika-Kibwika, Pauline;
Buzibye, Allan;
Lamorde, Mohammed;
Back, David J.;
Else, Laura J.;
Penchala, Sujan Dilly

Publication type:

Article

Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug-drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART.

Published in:

2018

By:

Roberts, Owain;
Rajoli, Rajith K R;
Back, David J;
Owen, Andrew;
Darin, Kristin M;
Fletcher, Courtney V;
Lamorde, Mohammed;
Scarsi, Kimberly K;
Siccardi, Marco

Publication type:

journal article

Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173509

By:

Seden, Kay;
Gibbons, Sara;
Marzolini, Catia;
Schapiro, Jonathan M.;
Burger, David M.;
Back, David J.;
Khoo, Saye H.

Publication type:

Article

Dexamethasone is a dose-dependent perpetrator of drug-drug interactions: implications for use in people living with HIV.

Published in:

2022

By:

Jacobs, Tom G;
Marzolini, Catia;
Back, David J;
Burger, David M

Publication type:

journal article

The challenging pathway towards the identification of SARS-CoV-2/COVID-19 therapeutics.

Published in:

2020

By:

Siccardi, Marco;
Schapiro, Jonathan;
Di Perri, Giovanni;
Back, David J

Publication type:

journal article

Recognition of Risk for Clinically Significant Drug Interactions among HIV-Infected Patients Receiving Antiretroviral Therapy.

Published in:

Clinical Infectious Diseases, 2010, v. 50, n. 10, p. 1419, doi. 10.1086/652149

By:

Evans-Jones, John G.;
Cottle, Lucy E.;
Back, David J.;
Gibbons, Sara;
Beeching, Nicholas J.;
Carey, Peter B.;
Khoo, Saye H.

Publication type:

Article

Association of a Single-Nucleotide Polymorphism in the Pregnane X Receptor (PXR 63396CrT) with Reduced Concentrations of Unboosted Atazanavir.

Published in:

Clinical Infectious Diseases, 2008, v. 47, n. 9, p. 1222, doi. 10.1086/592304

By:

Siccardi, Marco;
D'Avolio, Antonio;
Baietto, Lorena;
Gibbons, Sara;
Sciandra, Mauro;
Colucci, Daniela;
Bonora, Stefano;
Khoo, Saye;
Back, David J.;
Di Perri, Giovanni;
Owen, Andrew

Publication type:

Article

Absence of Opioid Withdrawal Symptoms in Patients Receiving Methadone and the Protease Inhibitor Lopinavir-Ritonavir.

Published in:

Clinical Infectious Diseases, 2002, v. 34, n. 8, p. 1143, doi. 10.1086/339541

By:

Clarke, Susan;
Mulcahy, Fiona;
Bergin, Colm;
Reynolds, Helen;
Boyle, Nicola;
Barry, Michael;
Back, David J.

Publication type:

Article

Pharmacokinetic Interactions of Nevirapine and Methadone and Guidelines for Use of Nevirapine to Treat Injection Drug Users.

Published in:

Clinical Infectious Diseases, 2001, v. 33, n. 9, p. 1595, doi. 10.1086/322519

By:

Clarke, Susan M.;
Mulcahy, Fiona M.;
Tjia, John;
Reynolds, Helen E.;
Gibbons, Sara E.;
Barry, Michael G.;
Back, David J.

Publication type:

Article

Toward Consensus on Correct Interpretation of Protein Binding in Plasma and Other Biological Matrices for COVID‐19 Therapeutic Development.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 1, p. 64, doi. 10.1002/cpt.2099

By:

Boffito, Marta;
Back, David J.;
Flexner, Charles;
Sjö, Peter;
Blaschke, Terrence F.;
Horby, Peter W.;
Cattaneo, Dario;
Acosta, Edward P.;
Anderson, Peter;
Owen, Andrew

Publication type:

Article

Prioritization of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 4, p. 775, doi. 10.1002/cpt.1909

By:

Arshad, Usman;
Pertinez, Henry;
Box, Helen;
Tatham, Lee;
Rajoli, Rajith K. R.;
Curley, Paul;
Neary, Megan;
Sharp, Joanne;
Liptrott, Neill J.;
Valentijn, Anthony;
David, Christopher;
Rannard, Steve P.;
O'Neill, Paul M.;
Aljayyoussi, Ghaith;
Pennington, Shaun H.;
Ward, Stephen A.;
Hill, Andrew;
Back, David J.;
Khoo, Saye H.;
Bray, Patrick G.

Publication type:

Article

Intracellular and plasma pharmacokinetics of nevirapine in human immunodeficiency virus-infected individuals

Published in:

Clinical Pharmacology & Therapeutics, 2005, v. 78, n. 2, p. 132, doi. 10.1016/j.clpt.2005.04.004

By:

Almond, Lisa M.;
Edirisinghe, Damitha;
Dalton, Mark;
Bonington, Alec;
Back, David J.;
Khoo, Saye H.

Publication type:

Article

Prescribing in COVID‐19 patients: Should we take into account inflammation?

Published in:

British Journal of Clinical Pharmacology, 2021, v. 87, n. 3, p. 719, doi. 10.1111/bcp.14524

By:

Marzolini, Catia;
Battegay, Manuel;
Sendi, Parham;
Back, David J.

Publication type:

Article

Response to ‘Communicating Information about Drug Interactions’.

Published in:

2008

By:

Back, David J.;
Gibbons, Sara E.

Publication type:

Letter

The role of clinical pharmacology in optimizing antiretroviral therapy.

Published in:

British Journal of Clinical Pharmacology, 2003, v. 55, n. 5, p. 473, doi. 10.1046/j.1365-2125.2003.01843.x

By:

Back, David J.;
Khoo, Saye H.

Publication type:

Article

The unbound percentage of saquinavir and indinavir remains constant throughout the dosing interval in HIV positive subjects.

Published in:

British Journal of Clinical Pharmacology, 2002, v. 54, n. 3, p. 262, doi. 10.1046/j.1365-2125.2002.01663.x

By:

Boffito, Marta;
Hoggard, Patrick G.;
Reynolds, Helen E.;
Bonora, Stefano;
Meaden, E Rhiannon;
Sinicco, Alessandro;
Di Perri, Giovanni;
Back, David J.

Publication type:

Article

The role of therapeutic drug monitoring in treatment of HIV infection.

Published in:

British Journal of Clinical Pharmacology, 2001, v. 52, p. 89S, doi. 10.1046/j.1365-2125.2001.00380.x

By:

Back, David J.;
Khoo, Saye H.;
Gibbons, Sara E.;
Merry, Concepta

Publication type:

Article

The role of therapeutic drug monitoring in treatment of HIV infection.

Published in:

British Journal of Clinical Pharmacology, 2001, v. 51, n. 4, p. 301, doi. 10.1046/j.1365-2125.2001.01380.x

By:

Back, David J.;
Khoo, Saye H.;
Gibbons, Sara E.;
Merry, Concepta

Publication type:

Article

The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz.

Published in:

British Journal of Clinical Pharmacology, 2001, v. 51, n. 3

By:

Clarke, Susan M.;
Mulcahy, Fiona M.;
Tjia, John;
Reynolds, Helen E.;
Gibbons, Sara E.;
Barry, Michael G.;
Back, David J.

Publication type:

Article

The intracellular activation of lamivudine (3TC) and determination of 2-deoxycytidine-5-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells.

Published in:

British Journal of Clinical Pharmacology, 2000, v. 50, n. 6, p. 597, doi. 10.1046/j.1365-2125.2000.00302.x

By:

Kewn, Stephen;
Hoggard, Patrick G.;
Sales, Sean D.;
Johnson, Mark A.;
Back, David J.

Publication type:

Article

The implications of P-glycoprotein in HIV: friend or foe?

Published in:

Fundamental & Clinical Pharmacology, 2005, v. 19, n. 3, p. 283, doi. 10.1111/j.1472-8206.2005.00324.x

By:

Owen, Andrew;
Chandler, Becky;
Back, David J.

Publication type:

Article

Drug-drug interactions: it is not only CYP450's which matter.

Published in:

2010

By:

Back, David J.

Publication type:

Abstract

Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction.

Published in:

Journal of Infectious Diseases, 2011, v. 204, n. 1, p. 145, doi. 10.1093/infdis/jir215

By:

Pushpakom, Sudeep P.;
Liptrott, Neill J.;
Rodríguez-Nóvoa, Sonia;
Labarga, Pablo;
Soriano, Vincent;
Albalater, Marta;
Hopper-Borge, Elizabeth;
Bonora, Stefano;
Di Perri, Giovanni;
Back, David J.;
Khoo, Saye;
Pirmohamed, Munir;
Owen, Andrew

Publication type:

Article

Recommendations for the Management of Drug–Drug Interactions Between the COVID‐19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1191, doi. 10.1002/cpt.2646

By:

Marzolini, Catia;
Kuritzkes, Daniel R.;
Marra, Fiona;
Boyle, Alison;
Gibbons, Sara;
Flexner, Charles;
Pozniak, Anton;
Boffito, Marta;
Waters, Laura;
Burger, David;
Back, David J.;
Khoo, Saye

Publication type:

Article

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.

Published in:

British Journal of Clinical Pharmacology, 1998, v. 45, n. 2, p. 107, doi. 10.1046/j.1365-2125.1998.00679.x

By:

Eagling, Victoria A.;
Tjia, John F.;
Back, David J.

Publication type:

Article

New cover-renewed commitment.

Published in:

British Journal of Clinical Pharmacology, 1997, v. 43, n. 1, p. 1, doi. 10.1111/j.1365-2125.1997.tb00128.x

By:

Back, David J.;
Mclnnes, Gordon T.;
Tucker, Geoff T.

Publication type:

Article