Works matching AU Bacchetta, Rosa

Results: 47

From IPEX syndrome to <italic>FOXP3</italic> mutation: a lesson on immune dysregulation.

Published in:

Annals of the New York Academy of Sciences, 2018, v. 1417, n. 1, p. 5, doi. 10.1111/nyas.13011

By:

Bacchetta, Rosa;
Barzaghi, Federica;
Roncarolo, Maria‐Grazia

Publication type:

Article

Neutralizing Anti-Cytokine Autoantibodies Against Interferon-α in Immunodysregulation Polyendocrinopathy Enteropathy X-Linked.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00544

By:

Rosenberg, Jacob M.;
Maccari, Maria E.;
Barzaghi, Federica;
Allenspach, Eric J.;
Pignata, Claudio;
Weber, Giovanna;
Torgerson, Troy R.;
Utz, Paul J.;
Bacchetta, Rosa

Publication type:

Article

Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines.

Published in:

European Journal of Immunology, 2002, v. 32, n. 8, p. 2237, doi. 10.1002/1521-4141(200208)32:8<2237::AID-IMMU2237>3.0.CO;2-2

By:

Bacchetta, Rosa;
Sartirana, Claudia;
Levings, Megan K.;
Bordignon, Claudio;
Narula, Satwant;
Roncarolo, Maria-Grazia

Publication type:

Article

Type 1 regulatory T (Tr1) cells: from the bench to the bedside.

Published in:

Journal of Translational Medicine, 2012, v. 10, n. Suppl 3, p. 1, doi. 10.1186/1479-5876-10-S3-I7

By:

Gregori, Silvia;
Bacchetta, Rosa;
Battaglia, Manuela;
Roncarolo, Maria Grazia

Publication type:

Article

Analyses of thymocyte commitment to regulatory T cell lineage in thymus of healthy subjects and patients with 22q11.2 deletion syndrome.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1088059

By:

Borna, Simon;
Dejene, Beruh;
Lakshmanan, Uma;
Schulze, Janika;
Weinberg, Kenneth;
Bacchetta, Rosa

Publication type:

Article

Corrigendum: Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells.

Published in:

Nature Medicine, 2014, v. 20, n. 10, p. 1217, doi. 10.1038/nm1014-1217c

By:

Gagliani, Nicola;
Magnani, Chiara F;
Huber, Samuel;
Gianolini, Monica E;
Pala, Mauro;
Licona-Limon, Paula;
Guo, Binggege;
Herbert, De'Broski R;
Bulfone, Alessandro;
Trentini, Filippo;
Di Serio, Clelia;
Bacchetta, Rosa;
Andreani, Marco;
Brockmann, Leonie;
Gregori, Silvia;
Flavell, Richard A;
Roncarolo, Maria-Grazia

Publication type:

Article

Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells.

Published in:

Nature Medicine, 2013, v. 19, n. 6, p. 739, doi. 10.1038/nm.3179

By:

Gagliani, Nicola;
Magnani, Chiara F;
Huber, Samuel;
Gianolini, Monica E;
Pala, Mauro;
Licona-Limon, Paula;
Guo, Binggege;
Herbert, De'Broski R;
Bulfone, Alessandro;
Trentini, Filippo;
Di Serio, Clelia;
Bacchetta, Rosa;
Andreani, Marco;
Brockmann, Leonie;
Gregori, Silvia;
Flavell, Richard A;
Roncarolo, Maria-Grazia

Publication type:

Article

Intergenerational and intrafamilial phenotypic variability in 22q11.2 Deletion syndrome subjects.

Published in:

BMC Medical Genetics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2350-15-1

By:

Cirillo, Emilia;
Giardino, Giuliana;
Gallo, Vera;
Puliafito, Pamela;
Azzari, Chiara;
Bacchetta, Rosa;
Cardinale, Fabio;
Cicalese, Maria Pia;
Consolini, Rita;
Martino, Silvana;
Martire, Baldassarre;
Molinatto, Cristina;
Plebani, Alessandro;
Scarano, Gioacchino;
Soresina, Annarosa;
Cancrini, Caterina;
Rossi, Paolo;
Digilio, Maria Cristina;
Pignata, Claudio

Publication type:

Article

Immunological outcome in haploidentical-HSC transplanted patients treated with IL-10-anergized donor T Cells.

Published in:

Frontiers in Immunology, 2014, v. 4, p. 1, doi. 10.3389/fimmu.2014.00016

By:

Bacchetta, Rosa;
Lucarelli, Barbarella;
Sartirana, Claudia;
Gregori, Silvia;
Lupo Stanghellini, Maria T.;
Miqueu, Patrick;
Tomiuk, Stefan;
Hernandez-Fuentes, Maria;
Gianolini, Monica E.;
Greco, Raffaella;
Bernardi, Massimo;
Zappone, Elisabetta;
Rossini, Silvano;
Janssen, Uwe;
Ambrosi, Alessandro;
Salomoni, Monica;
Peccatori, Jacopo;
Ciceri, Fabio;
Roncarolo, Maria-Grazia

Publication type:

Article

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: a paradigm of immunodeficiency with autoimmunity.

Published in:

Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00211

By:

Barzaghi, Federica;
Passerini, Laura;
Bacchetta, Rosa

Publication type:

Article

TH17 cells in autoimmunity and immunodeficiency: protective or pathogenic?

Published in:

Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00129

By:

Marwaha, Ashish K.;
Leung, Nicole J.;
McMurchy, Alicia N.;
Levings, Megan K.;
Bacchetta, Rosa;
Annunziato, Francesco

Publication type:

Article

Epigenetic immune cell counting in human blood samples for immunodiagnostics.

Published in:

Science Translational Medicine, 2018, v. 10, n. 452, p. 1, doi. 10.1126/scitranslmed.aan3508

By:

Baron, Udo;
Werner, Jeannette;
Schildknecht, Konstantin;
Schulze, Janika J.;
Mulu, Andargaschew;
Liebert, Uwe-Gerd;
Sack, Ulrich;
Speckmann, Carsten;
Gossen, Manfred;
Wong, Ronald J.;
Stevenson, David K.;
Babel, Nina;
Schürmann, Dirk;
Baldinger, Tina;
Bacchetta, Rosa;
Grützkau, Andreas;
Borte, Stephan;
Olek, Sven

Publication type:

Article

T-Cell Subsets and Their Cytokine Profiles in Transplantation and Tolerance.

Published in:

Annals of the New York Academy of Sciences, 1995, v. 770, n. 1, p. 141, doi. 10.1111/j.1749-6632.1995.tb31051.x

By:

GROUX, HERVÉ;
ROULEAU, MATTHIEU;
BACCHETTA, ROSA;
RONCAROLO, MARIA-GRAZIA

Publication type:

Article

Human inborn errors of immunity: An expanding universe.

Published in:

Science Immunology, 2020, v. 5, n. 49, p. 1, doi. 10.1126/sciimmunol.abb1662

By:

Notarangelo, Luigi D.;
Bacchetta, Rosa;
Casanova, Jean-Laurent;
Su, Helen C.

Publication type:

Article

Clinical improvement and normalized Th1 cytokine profile in early and long-term interferon-α treatment in a suspected case of hyper-IgE syndrome.

Published in:

Pediatric Allergy & Immunology, 2008, v. 19, n. 6, p. 564, doi. 10.1111/j.1399-3038.2007.00683.x

By:

Benninghoff, Ulrike;
Cattaneo, Federica;
Aiuti, Alessandro;
Flores-D’Arcais, Alberto;
Gelmetti, Carlo;
Viscardi, Matteo;
Callegaro, Luciano;
Mirolo, Massimiliano;
Ambrosi, Alessandro;
Roncarolo, Maria Grazia;
Bacchetta, Rosa

Publication type:

Article

Editorial: Inborn Errors of Immunity (IEI) breaking immune homeostasis and tolerance: a key role for T regulatory cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1532079

By:

De Rosa, Veronica;
Sogkas, Georgios;
Bacchetta, Rosa

Publication type:

Article

Hurdles in therapy with regulatory T cells.

Published in:

Science Translational Medicine, 2015, v. 7, n. 304, p. 1, doi. 10.1126/scitranslmed.aaa7721

By:

Trzonkowski, Piotr;
Bacchetta, Rosa;
Battaglia, Manuela;
Berglund, David;
Bohnenkamp, Hermann Richard;
Brinke, Anja ten;
Bushell, Andrew;
Cools, Nathalie;
Geissler, Edward K.;
Gregori, Silvia;
van Ham, S. Marieke;
Hilkens, Catharien;
Hutchinson, James A.;
Lombardi, Giovanna;
Madrigal, J. Alejandro;
Marek-Trzonkowska, Natalia;
Martinez-Caceres, Eva M.;
Roncarolo, Maria Grazia;
Sanchez-Ramon, Silvia;
Saudemont, Aurore

Publication type:

Article

CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer.

Published in:

Science Translational Medicine, 2013, v. 5, n. 215, p. 1, doi. 10.1126/scitranslmed.3007320

By:

Passerini, Laura;
Mel, Eva Rossi;
Sartirana, Claudia;
Fousteri, Georgia;
Bondanza, Attilio;
Naldini, Luigi;
Roncarolo, Maria Grazia;
Bacchetta, Rosa

Publication type:

Article

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells.

Published in:

Nature Biotechnology, 2015, v. 33, n. 9, p. 985, doi. 10.1038/nbt.3290

By:

Hendel, Ayal;
Bak, Rasmus O;
Clark, Joseph T;
Kennedy, Andrew B;
Ryan, Daniel E;
Roy, Subhadeep;
Steinfeld, Israel;
Lunstad, Benjamin D;
Kaiser, Robert J;
Wilkens, Alec B;
Bacchetta, Rosa;
Tsalenko, Anya;
Dellinger, Douglas;
Bruhn, Laurakay;
Porteus, Matthew H

Publication type:

Article

Reappraisal of in utero Stem Cell Transplantation Based on Long-Term Results.

Published in:

Fetal Diagnosis & Therapy, 2004, v. 19, n. 4, p. 305, doi. 10.1159/000077957

By:

Touraine, Jean-Louis;
Raudrant, Daniel;
Golfier, François;
Rebaud, Albert;
Sembeil, Rachel;
Roncarolo, Maria-Grazia;
Bacchetta, Rosa;
D'Oiron, Roseline;
Lambert, Thierry;
Gebuhrer, Lucette

Publication type:

Article

Forkhead box P3: The Peacekeeper of the Immune System.

Published in:

International Reviews of Immunology, 2014, v. 33, n. 2, p. 129, doi. 10.3109/08830185.2013.863303

By:

Passerini, Laura;
Santoni de Sio, Francesca Romana;
Roncarolo, Maria Grazia;
Bacchetta, Rosa

Publication type:

Article

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2017.01844

By:

Fuchs, Anke;
Gliwiński, Mateusz;
Grageda, Nathali;
Spiering, Rachel;
Abbas, Abul K.;
Appel, Silke;
Bacchetta, Rosa;
Battaglia, Manuela;
Berglund, David;
Blazar, Bruce;
Bluestone, Jeffrey A.;
Bornhäuser, Martin;
ten Brinke, Anja;
Brusko, Todd M.;
Cools, Nathalie;
Cuturi, Maria Cristina;
Geissler, Edward;
Giannoukakis, Nick;
Gołab, Karolina;
Hafler, David A.

Publication type:

Article

Forkhead-Box-P3 Gene Transfer in Human CD4+ T Conventional Cells for the Generation of Stable and Efficient Regulatory T Cells, Suitable for Immune Modulatory Therapy.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01282

By:

Passerini, Laura;
Bacchetta, Rosa

Publication type:

Article

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.

Published in:

International Immunology, 2008, v. 20, n. 3, p. 421, doi. 10.1093/intimm/dxn002

By:

Laura Passerini;
Sarah E. Allan;
Manuela Battaglia;
Sara Di Nunzio;
Alicia N. Alstad;
Megan K. Levings;
Maria G. Roncarolo;
Rosa Bacchetta

Publication type:

Article

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production.

Published in:

International Immunology, 2007, v. 19, n. 4, p. 345, doi. 10.1093/intimm/dxm014

By:

Sarah E. Allan;
Sarah Q. Crome;
Natasha K. Crellin;
Laura Passerini;
Theodore S. Steiner;
Rosa Bacchetta;
Maria G. Roncarolo;
Megan K. Levings

Publication type:

Article

The Role of IL-10 and TGF-β in the Differentiation and Effector Function of T Regulatory Cells.

Published in:

International Archives of Allergy & Immunology, 2002, v. 129, n. 4, p. 263, doi. 10.1159/000067596

By:

Levings, Megan K.;
Bacchetta, Rosa;
Schulz, Ute;
Roncarolo, Maria Grazia

Publication type:

Article

Case report: Refractory Evans syndrome in two patients with spondyloenchondrodysplasia with immune dysregulation treated successfully with JAK1/JAK2 inhibition.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1328005

By:

Gernez, Yael;
Narula, Mansi;
Cepika, Alma-Martina;
Camacho, Juanita Valdes;
Hoyte, Elisabeth G.;
Mouradian, Kirsten;
Glader, Bertil;
Singh, Deepika;
Sathi, Bindu;
Rao, Latha;
Tolin, Ana L.;
Weinberg, Kenneth I.;
Lewis, David B.;
Bacchetta, Rosa;
Weinacht, Katja G.

Publication type:

Article

Identification of STAT5A and STAT5B Target Genes in Human T Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086790

By:

Kanai, Takahiro;
Seki, Scott;
Jenks, Jennifer A.;
Kohli, Arunima;
Kawli, Trupti;
Martin, Dorrelyn Patacsil;
Snyder, Michael;
Bacchetta, Rosa;
Nadeau, Kari C.

Publication type:

Article

Autoantibodies to Harmonin and Villin Are Diagnostic Markers in Children with IPEX Syndrome.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078664

By:

Lampasona, Vito;
Passerini, Laura;
Barzaghi, Federica;
Lombardoni, Carlo;
Bazzigaluppi, Elena;
Brigatti, Cristina;
Bacchetta, Rosa;
Bosi, Emanuele

Publication type:

Article

FOXP3 TSDR Measurement Could Assist Variant Classification and Diagnosis of IPEX Syndrome.

Published in:

Journal of Clinical Immunology, 2023, v. 43, n. 3, p. 662, doi. 10.1007/s10875-022-01428-w

By:

Wyatt, Rebecca C.;
Olek, Sven;
De Franco, Elisa;
Samans, Bjoern;
Patel, Kashyap;
Houghton, Jayne;
Walter, Steffi;
Schulze, Janika;
Bacchetta, Rosa;
Hattersley, Andrew T.;
Flanagan, Sarah E.;
Johnson, Matthew B.

Publication type:

Article

Regulatory T cells and their roles in immune dysregulation and allergy.

Published in:

Immunologic Research, 2014, v. 58, n. 2/3, p. 358, doi. 10.1007/s12026-014-8512-5

By:

Pellerin, Laurence;
Jenks, Jennifer;
Bégin, Philippe;
Bacchetta, Rosa;
Nadeau, Kari

Publication type:

Article

FOXP3 deficiency, from the mechanisms of the disease to curative strategies.

Published in:

Immunological Reviews, 2024, v. 322, n. 1, p. 244, doi. 10.1111/imr.13289

By:

Borna, Simon;
Meffre, Eric;
Bacchetta, Rosa

Publication type:

Article

Clinical tolerance in allogeneic hematopoietic stem cell transplantation.

Published in:

Immunological Reviews, 2011, v. 241, n. 1, p. 145, doi. 10.1111/j.1600-065X.2011.01010.x

By:

Roncarolo, Maria-Grazia;
Gregori, Silvia;
Lucarelli, Barbarella;
Ciceri, Fabio;
Bacchetta, Rosa

Publication type:

Article

CD4+ T-regulatory cells: toward therapy for human diseases.

Published in:

Immunological Reviews, 2008, v. 223, n. 1, p. 391, doi. 10.1111/j.1600-065X.2008.00634.x

By:

Allan, Sarah E.;
Broady, Raewyn;
Gregori, Silvia;
Himmel, Megan E.;
Locke, Natasha;
Roncarolo, Maria Grazia;
Bacchetta, Rosa;
Levings, Megan K.

Publication type:

Article

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

Published in:

Immunological Reviews, 2006, v. 212, n. 1, p. 28, doi. 10.1111/j.0105-2896.2006.00420.x

By:

Roncarolo, Maria Grazia;
Gregori, Silvia;
Battaglia, Manuela;
Bacchetta, Rosa;
Fleischhauer, Katharina;
Levings, Megan K.

Publication type:

Article

Type 1 T regulatory cells.

Published in:

Immunological Reviews, 2001, v. 182, n. 1, p. 68, doi. 10.1034/j.1600-065x.2001.1820105.x

By:

Roncarolo, Maria Grazia;
Bacchetta, Rosa;
Bordignon, Claudio;
Narula, Satwant;
Levings, Megan K.

Publication type:

Article

Human‐engineered Treg‐like cells suppress FOXP3‐deficient T cells but preserve adaptive immune responses in vivo.

Published in:

Clinical & Translational Immunology, 2020, v. 9, n. 11, p. 1, doi. 10.1002/cti2.1214

By:

Sato, Yohei;
Passerini, Laura;
Piening, Brian D;
Uyeda, Molly Javier;
Goodwin, Marianne;
Gregori, Silvia;
Snyder, Michael P;
Bertaina, Alice;
Roncarolo, Maria‐Grazia;
Bacchetta, Rosa

Publication type:

Article

Thymic origins of autoimmunity—lessons from inborn errors of immunity.

Published in:

Seminars in Immunopathology, 2021, v. 43, n. 1, p. 65, doi. 10.1007/s00281-020-00835-8

By:

Bacchetta, Rosa;
Weinberg, Kenneth

Publication type:

Article

Regulated and Multiple miRNA and siRNA Delivery Into Primary Cells by a Lentiviral Platform.

Published in:

Molecular Therapy, 2009, v. 17, n. 6, p. 1039, doi. 10.1038/mt.2009.48

By:

Amendola, Mario;
Passerini, Laura;
Pucci, Ferdinando;
Gentner, Bernhard;
Bacchetta, Rosa;
Naldini, Luigi

Publication type:

Article

Generation of Potent and Stable Human CD4+ T Regulatory Cells by Activation-independent Expression of FOXP3.

Published in:

Molecular Therapy, 2008, v. 16, n. 1, p. 194, doi. 10.1038/sj.mt.6300341

By:

Allan, Sarah E.;
Alstad, Alicia N.;
Merindol, Natacha;
Crellin, Natasha K.;
Amendola, Mario;
Bacchetta, Rosa;
Naldini, Luigi;
Roncarolo, Maria Grazia;
Soudeyns, Hugo;
Levings, Megan K.

Publication type:

Article

Co-Expression of FOXP3FL and FOXP3Δ2 Isoforms Is Required for Optimal Treg-Like Cell Phenotypes and Suppressive Function.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.752394

By:

Sato, Yohei;
Liu, Jessica;
Lee, Esmond;
Perriman, Rhonda;
Roncarolo, Maria Grazia;
Bacchetta, Rosa

Publication type:

Article

BHLHE40 Regulates IL-10 and IFN- γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.683680

By:

Uyeda, Molly Javier;
Freeborn, Robert A.;
Cieniewicz, Brandon;
Romano, Rosa;
Chen, Ping;
Liu, Jeffrey Mao-Hwa;
Thomas, Benjamin;
Lee, Esmond;
Cepika, Alma-Martina;
Bacchetta, Rosa;
Roncarolo, Maria Grazia

Publication type:

Article

Towards gene therapy for IPEX syndrome.

Published in:

European Journal of Immunology, 2022, v. 52, n. 5, p. 705, doi. 10.1002/eji.202149210

By:

Borna, Simon;
Lee, Esmond;
Sato, Yohei;
Bacchetta, Rosa

Publication type:

Article

Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells.

Published in:

European Journal of Immunology, 2011, v. 41, n. 6, p. 1652, doi. 10.1002/eji.201041120

By:

Magnani, Chiara F.;
Alberigo, Giada;
Bacchetta, Rosa;
Serafini, Giorgia;
Andreani, Marco;
Roncarolo, Maria Grazia;
Gregori, Silvia

Publication type:

Article

Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome.

Published in:

European Journal of Immunology, 2011, v. 41, n. 4, p. 1120, doi. 10.1002/eji.201040909

By:

Passerini, Laura;
Di Nunzio, Sara;
Gregori, Silvia;
Gambineri, Eleonora;
Cecconi, Massimiliano;
Seidel, Markus G.;
Cazzola, Giantonio;
Perroni, Lucia;
Tommasini, Alberto;
Vignola, Silvia;
Guidi, Luisa;
Roncarolo, Maria G.;
Bacchetta, Rosa

Publication type:

Article

Defective regulatory and effector T cell functions in patients with FOXP3 mutations.

Published in:

2006

By:

Bacchetta, Rosa;
Passerini, Laura;
Gambineri, Eleonora;
Minyue Dai;
Allan, Sarah E.;
Perroni, Lucia;
Dagna-Bricarelli, Franca;
Sartirana, Claudia;
Matthes-Martin, Susanne;
Lawitschka, Anita;
Azzari, Chiara;
Ziegler, Steven F.;
Levings, Megan K.;
Roncarolo, Maria Grazia;
Dai, Minyue

Publication type:

journal article

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.

Published in:

2005

By:

Allan, Sarah E.;
Passerini, Laura;
Bacchetta, Rosa;
Crellin, Natasha;
Dai, Minyue;
Orban, Paul C.;
Ziegler, Steven F.;
Roncarolo, Maria Grazia;
Levings, Megan K.

Publication type:

journal article