Works by Babkov, Denis A.

Results: 32

Guanidine Derivatives of Quinazoline-2,4(1 H ,3 H)-Dione as NHE-1 Inhibitors and Anti-Inflammatory Agents.

Published in:

Life (2075-1729), 2022, v. 12, n. 10, p. 1647, doi. 10.3390/life12101647

By:

Spasov, Alexander;
Ozerov, Alexander;
Kosolapov, Vadim;
Gurova, Natalia;
Kucheryavenko, Aida;
Naumenko, Ludmila;
Babkov, Denis;
Sirotenko, Viktor;
Taran, Alena;
Borisov, Alexander;
Sokolova, Elena;
Klochkov, Vladlen;
Merezhkina, Darya;
Miroshnikov, Mikhail;
Ovsyankina, Nadezhda;
Smirnov, Alexey;
Velikorodnaya, Yulia

Publication type:

Article

Resveratrol and Extra Virgin Olive Oil: Protective Agents Against Age-Related Disease.

Published in:

Nutrients, 2024, v. 16, n. 24, p. 4258, doi. 10.3390/nu16244258

By:

Morkovin, Evgeny;
Litvinov, Roman;
Koushner, Alexey;
Babkov, Denis

Publication type:

Article

Spacered With Tetrazole Oleanolic and Ursolic Indolo‐Acids Are Strong Inhibitors of α‐Glucosidase.

Published in:

Chemical Biology & Drug Design, 2025, v. 105, n. 3, p. 1, doi. 10.1111/cbdd.70065

By:

Petrova, Anastasiya V.;
Babkov, Denis A.;
Danilov, Roman D.;
Sokolova, Elena V.;
Kazakova, Oxana B.;
Spasov, Alexander A.

Publication type:

Article

Directed Design, Screening and Antiglycation Activity for 3‐Substituted Thiazolium Derivatives, New Analogs of Alagebrium.

Published in:

Chemical Biology & Drug Design, 2024, v. 104, n. 4, p. 1, doi. 10.1111/cbdd.14630

By:

Zhukovskaya, Olga N.;
Kolodina, Alexandra A.;
Litvinov, Roman;
Ibragimova, Umida;
Valuisky, Nikita;
Sorokina, Svetlana;
Zhukova, Xenia;
Pobedinskaya, Diana Yu.;
Borisov, Alexander;
Babkov, Denis A.;
Spasov, Alexander A.

Publication type:

Article

Development of New Antimicrobial Oleanonic Acid Polyamine Conjugates.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 1, p. 94, doi. 10.3390/antibiotics11010094

By:

Khusnutdinova, Elmira F.;
Sinou, Véronique;
Babkov, Denis A.;
Kazakova, Oxana;
Brunel, Jean Michel

Publication type:

Article

Synthesis and multifaceted pharmacological activity of novel quinazoline NHE-1 inhibitors.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03722-w

By:

Spasov, Alexander;
Ozerov, Alexander;
Vassiliev, Pavel;
Kosolapov, Vadim;
Gurova, Natalia;
Kucheryavenko, Aida;
Naumenko, Ludmila;
Babkov, Denis;
Sirotenko, Viktor;
Taran, Alena;
Litvinov, Roman;
Borisov, Alexander;
Klochkov, Vladlen;
Merezhkina, Darya;
Miroshnikov, Mikhail;
Uskov, Georgy;
Ovsyankina, Nadezhda

Publication type:

Article

Discovery and evaluation of biphenyl derivatives of 2‐iminobenzimidazoles as prototype dual PTP1B inhibitors and AMPK activators with in vivo antidiabetic activity.

Published in:

Chemical Biology & Drug Design, 2023, v. 101, n. 4, p. 896, doi. 10.1111/cbdd.14198

By:

Babkov, Denis A.;
Zhukovskaya, Olga N.;
Brigadirova, Anastasia A.;
Prilepskaya, Diana R.;
Kolodina, Alexandra A.;
Abbas, Abbas Haider S.;
Morkovnik, Anatolii S.;
Sobhia, M. Elizabeth;
Ghosh, Ketan;
Spasov, Alexander A.

Publication type:

Article

Synthesis and biological evaluation of 2-acylbenzofuranes as novel α-glucosidase inhibitors with hypoglycemic activity.

Published in:

Chemical Biology & Drug Design, 2017, v. 90, n. 6, p. 1184, doi. 10.1111/cbdd.13038

By:

Spasov, Alexander A.;
Babkov, Denis A.;
Prokhorova, Tatyana Yu;
Sturova, Ekaterina A.;
Muleeva, Diana R.;
Demidov, Maxim R.;
Osipov, Dmitry V.;
Osyanin, Vitaly A.;
Klimochkin, Yuri N.

Publication type:

Article

5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis.

Published in:

Chemical Biology & Drug Design, 2015, v. 86, n. 6, p. 1387, doi. 10.1111/cbdd.12603

By:

Matyugina, Elena;
Novikov, Mikhail;
Babkov, Denis;
Ozerov, Alexander;
Chernousova, Larisa;
Andreevskaya, Sofia;
Smirnova, Tatiana;
Karpenko, Inna;
Chizhov, Alexander;
Murthu, Pravin;
Lutz, Stefan;
Kochetkov, Sergei;
Seley ‐ Radtke, Katherine L.;
Khandazhinskaya, Anastasia L.

Publication type:

Article

Indolin‐2‐Ones: A New Approach to Inflammation, Targeting LPS via GSK3β/NLRP3.

Published in:

ChemistrySelect, 2025, v. 10, n. 5, p. 1, doi. 10.1002/slct.202403325

By:

Klochkov, Vladlen;
Babkov, Denis;
Borisov, Alexander;
Ianalieva, Laura;
Danilov, Roman;
Bezsonova, Elena;
Sosonyuk, Sergey;
Lozinskaya, Natalia;
Spasov, Alexander

Publication type:

Article

6-Nitroazolo[1,5- a]pyrimidin-7(4 H)-ones as Antidiabetic Agents.

Published in:

Archiv der Pharmazie, 2017, v. 350, n. 12, p. n/a, doi. 10.1002/ardp.201700226

By:

Spasov, Alexander A.;
Babkov, Denis A.;
Sysoeva, Valentina A.;
Litvinov, Roman A.;
Shamshina, Darya D.;
Ulomsky, Evgeny N.;
Savateev, Konstantin V.;
Fedotov, Viktor V.;
Slepukhin, Pavel A.;
Chupakhin, Oleg N.;
Charushin, Valery N.;
Rusinov, Vladimir L.

Publication type:

Article

Synthesis and Evaluation of Novel [1,2,4]Triazolo[5,1- c][1,2,4]-triazines and Pyrazolo[5,1- c][1,2,4]triazines as Potential Antidiabetic Agents.

Published in:

Archiv der Pharmazie, 2017, v. 350, n. 5, p. n/a, doi. 10.1002/ardp.201600361

By:

Rusinov, Vladimir L.;
Sapozhnikova, Irina M.;
Bliznik, Anastasiya M.;
Chupakhin, Oleg N.;
Charushin, Valery N.;
Spasov, Alexander A.;
Vassiliev, Pavel M.;
Kuznetsova, Valentina A.;
Rashchenko, Andrey I.;
Babkov, Denis A.

Publication type:

Article

Derivatization of Abietane Acids by Peptide-like Substituents Leads to Submicromolar Cytotoxicity at NCI-60 Panel.

Published in:

Molecules, 2024, v. 29, n. 15, p. 3532, doi. 10.3390/molecules29153532

By:

Tretyakova, Elena;
Smirnova, Anna;
Babkov, Denis;
Kazakova, Oxana

Publication type:

Article

3-Arylidene-2-oxindoles as Potent NRH:Quinone Oxidoreductase 2 Inhibitors.

Published in:

Molecules, 2023, v. 28, n. 3, p. 1174, doi. 10.3390/molecules28031174

By:

Lozinskaya, Natalia A.;
Bezsonova, Elena N.;
Dubar, Meriam;
Melekhina, Daria D.;
Bazanov, Daniil R.;
Bunev, Alexander S.;
Grigor'eva, Olga B.;
Klochkov, Vladlen G.;
Sokolova, Elena V.;
Babkov, Denis A.;
Spasov, Alexander A.;
Sosonyuk, Sergey E.

Publication type:

Article

Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury.

Published in:

Molecules, 2023, v. 28, n. 2, p. 741, doi. 10.3390/molecules28020741

By:

Spasov, Alexander;
Ovchinnikova, Irina;
Fedorova, Olga;
Titova, Yulia;
Babkov, Denis;
Kosolapov, Vadim;
Borisov, Alexander;
Sokolova, Elena;
Klochkov, Vladlen;
Skripka, Maria;
Velikorodnaya, Yulia;
Smirnov, Alexey;
Rusinov, Gennady;
Charushin, Valery

Publication type:

Article

6-(Tetrazol-5-yl)-7-aminoazolo[1,5- a ]pyrimidines as Novel Potent CK2 Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 24, p. 8697, doi. 10.3390/molecules27248697

By:

Urakov, Grigoriy V.;
Savateev, Konstantin V.;
Kotovskaya, Svetlana K.;
Rusinov, Vladimir L.;
Spasov, Alexandr A.;
Babkov, Denis A.;
Sokolova, Elena V.

Publication type:

Article

CK2 Inhibition and Antitumor Activity of 4,7-Dihydro-6-nitroazolo[1,5-a]pyrimidines.

Published in:

Molecules, 2022, v. 27, n. 16, p. 5239, doi. 10.3390/molecules27165239

By:

Lyapustin, Daniil N.;
Kotovskaya, Svetlana K.;
Butorin, Ilya I.;
Ulomsky, Evgeny N.;
Rusinov, Vladimir L.;
Babkov, Denis A.;
Pokhlebin, Alexander A.;
Spasov, Alexander A.;
Melekhin, Vsevolod V.;
Tokhtueva, Maria D.;
Shcheglova, Anna V.;
Makeev, Oleg G.

Publication type:

Article

Evaluation of Cytotoxicity and α-Glucosidase Inhibitory Activity of Amide and Polyamino-Derivatives of Lupane Triterpenoids.

Published in:

Molecules, 2020, v. 25, n. 20, p. 4833, doi. 10.3390/molecules25204833

By:

Kazakova, Oxana B.;
Giniyatullina, Gul'nara V.;
Mustafin, Akhat G.;
Babkov, Denis A.;
Sokolova, Elena V.;
Spasov, Alexander A.;
Oyelere, Adegboyega K.

Publication type:

Article

Hypoglycemic potential of cyclic guanidine derivatives.

Published in:

Pure & Applied Chemistry, 2017, v. 89, n. 8, p. 1007, doi. 10.1515/pac-2016-1024

By:

Spasov, Alexander A.;
Vassiliev, Pavel M.;
Lenskaya, Karina V.;
Anisimova, Vera A.;
Kuzmenko, Tatyana A.;
Morkovnik, Anatolii S.;
Kosolapov, Vadim A.;
Babkov, Denis A.

Publication type:

Article

Synthesis and pharmacological properties of novel guanidine derivatives of quinazoline-2,4(1H,3H)-dione.

Published in:

Research Results in Pharmacology, 2024, v. 10, n. 3, p. 73, doi. 10.18413/rrpharmacology.10.486

By:

Ozerov, Alexander A.;
Merezhkina, Daria V.;
Gurova, Natalia A.;
Naumenko, Lyudmila V.;
Babkov, Denis A.;
Sirotenko, Victor S.;
Litvinov, Roman A.;
Taran, Alena S.;
Stepanova, Nadezhda V.;
Ibragimova, Umida M.;
Spasov, Alexander A.;
Kosolapov, Vadim A.

Publication type:

Article

Discovery of Nitro-azolo[1,5- a ]pyrimidines with Anti-Inflammatory and Protective Activity against LPS-Induced Acute Lung Injury.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 5, p. 537, doi. 10.3390/ph15050537

By:

Spasov, Alexander;
Kosolapov, Vadim;
Babkov, Denis;
Klochkov, Vladlen;
Sokolova, Elena;
Miroshnikov, Mikhail;
Borisov, Alexander;
Velikorodnaya, Yulia;
Smirnov, Alexey;
Savateev, Konstantin;
Fedotov, Victor;
Kotovskaya, Svetlana;
Rusinov, Vladimir

Publication type:

Article

Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8841, doi. 10.3390/ijms25168841

By:

Babkov, Denis;
Eliseeva, Natalya;
Adzhienko, Kristina;
Bagmetova, Viktoria;
Danilov, Dmitry;
McReynolds, Cynthia B.;
Morisseau, Christophe;
Hammock, Bruce D.;
Burmistrov, Vladimir

Publication type:

Article

New Molecules of Diterpene Origin with Inhibitory Properties toward α-Glucosidase.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13535, doi. 10.3390/ijms232113535

By:

Tretyakova, Elena;
Smirnova, Irina;
Kazakova, Oxana;
Nguyen, Ha Thi Thu;
Shevchenko, Alina;
Sokolova, Elena;
Babkov, Denis;
Spasov, Alexander

Publication type:

Article

Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 18, p. N.PAG, doi. 10.3390/ijms231810710

By:

Burmistrov, Vladimir;
Morisseau, Christophe;
Babkov, Denis A.;
Golubeva, Tatiana;
Pitushkin, Dmitry;
Sokolova, Elena V.;
Vasipov, Vladimir;
Kuznetsov, Yaroslav;
Bazhenov, Sergey V.;
Novoyatlova, Uliana S.;
Bondarev, Nikolay A.;
Manukhov, Ilya V.;
Osipova, Victoria;
Berberova, Nadezhda;
Spasov, Alexander A.;
Butov, Gennady M.;
Hammock, Bruce D.

Publication type:

Article

From Marine Metabolites to the Drugs of the Future: Squalamine, Trodusquemine, Their Steroid and Triterpene Analogues †.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1075, doi. 10.3390/ijms23031075

By:

Kazakova, Oxana;
Giniyatullina, Gulnara;
Babkov, Denis;
Wimmer, Zdenek

Publication type:

Article

Ru(III) Complexes with Lonidamine-Modified Ligands.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13468, doi. 10.3390/ijms222413468

By:

Shutkov, Ilya A.;
Okulova, Yulia N.;
Tyurin, Vladimir Yu.;
Sokolova, Elena V.;
Babkov, Denis A.;
Spasov, Alexander A.;
Gracheva, Yulia A.;
Schmidt, Claudia;
Kirsanov, Kirill I.;
Shtil, Alexander A.;
Redkozubova, Olga M.;
Shevtsova, Elena F.;
Milaeva, Elena R.;
Ott, Ingo;
Nazarov, Alexey A.

Publication type:

Article

Novel A-Ring Chalcone Derivatives of Oleanolic and Ursolic Amides with Anti-Proliferative Effect Mediated through ROS-Triggered Apoptosis.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 9796, doi. 10.3390/ijms22189796

By:

Khusnutdinova, Elmira;
Petrova, Anastasiya;
Zileeva, Zulfia;
Kuzmina, Ulyana;
Zainullina, Liana;
Vakhitova, Yulia;
Babkov, Denis;
Kazakova, Oxana

Publication type:

Article

Synthesis, Cytotoxicity, and α-glucosidase Inhibitory Activity of Triterpenic and Sitosterol Tetrazole Derivatives.

Published in:

Chemistry of Heterocyclic Compounds, 2021, v. 57, n. 9, p. 920, doi. 10.1007/s10593-021-03001-6

By:

Petrova, Anastasiya V.;
Poptsov, Alexander I.;
Thu, Ha Nguyen Thi;
Van Tuyen, Nguyen;
Khusnutdinova, Elmira F.;
Babkov, Denis A.;
Kazakova, Oxana B.

Publication type:

Article

New Organometallic Ru(II) Compounds with Lonidamine Motif as Antitumor Agents.

Published in:

Pharmaceutics, 2023, v. 15, n. 5, p. 1366, doi. 10.3390/pharmaceutics15051366

By:

Shutkov, Ilya A.;
Okulova, Yulia N.;
Mazur, Dmitrii M.;
Melnichuk, Nikolai A.;
Babkov, Denis A.;
Sokolova, Elena V.;
Spasov, Alexander A.;
Milaeva, Elena R.;
Nazarov, Alexey A.

Publication type:

Article

Efficient synthesis and evaluation of therapeutic potential of fluorine containing 2-arylchromen-4-ones.

Published in:

Molecular Diversity, 2025, v. 29, n. 2, p. 1427, doi. 10.1007/s11030-024-10925-6

By:

Troshkova, Nadezhda;
Politanskaya, Larisa;
Wang, Jiaying;
Niukalova, Maria;
Khasanov, Shokhrukh;
Esaulkova, Iana;
Zarubaev, Vladimir;
Boltneva, Natalia;
Rudakova, Elena;
Kovaleva, Nadezhda;
Serebryakova, Olga;
Makhaeva, Galina;
Valuisky, Nikita;
Ibragimova, Umida;
Litvinov, Roman;
Babkov, Denis;
Usenov, Kubanych;
Chertenkov, Matvey;
Pokrovsky, Mikhail;
Cheresiz, Sergey

Publication type:

Article

α-Glucosidase Inhibitors Based on Oleanolic Acid for the Treatment of Immunometabolic Disorders.

Published in:

Applied Sciences (2076-3417), 2023, v. 13, n. 16, p. 9269, doi. 10.3390/app13169269

By:

Petrova, Anastasiya V.;
Babkov, Denis A.;
Khusnutdinova, Elmira F.;
Baikova, Irina P.;
Kazakova, Oxana B.;
Sokolova, Elena V.;
Spasov, Alexander A.

Publication type:

Article

A Novel Dipterocarpol Derivative That Targets Alpha‐Glucosidase and NLRP3 Inflammasome Activity for Treatment of Diabetes Mellitus.

Published in:

Chemistry & Biodiversity, 2025, v. 22, n. 1, p. 1, doi. 10.1002/cbdv.202401626

By:

Danilov, Roman D.;
Smirnova, Irina E.;
Galimova, Zarema I.;
Sokolova, Elena V.;
Lukyanov, Andrey V.;
Kalitin, Konstantin Y.;
Mukha, Olga Y.;
Babkov, Denis A.;
Kazakova, Oxana B.;
Spasov, Alexander A.

Publication type:

Article