Works matching AU BUGLIANI, MARCO

Results: 61
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    Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.

    Published in:
    Nature Genetics, 2009, v. 41, n. 1, p. 82, doi. 10.1038/ng.288
    By:
    • Lyssenko, Valeriya;
    • Nagorny, Cecilia L. F.;
    • Erdos, Michael R.;
    • Wierup, Nils;
    • Jonsson, Anna;
    • Spégel, Peter;
    • Bugliani, Marco;
    • Saxena, Richa;
    • Fex, Malin;
    • Pulizzi, Nicolo;
    • Isomaa, Bo;
    • Tuomi, Tiinamaija;
    • Nilsson, Peter;
    • Kuusisto, Johanna;
    • Tuomilehto, Jaakko;
    • Boehnke, Michael;
    • Altshuler, David;
    • Sundler, Frank;
    • Eriksson, Johan G.;
    • Jackson, Anne U.
    Publication type:
    Article
    4

    Lipotoxicity disrupts incretin-regulated human β cell connectivity.

    Published in:
    Journal of Clinical Investigation, 2013, v. 123, n. 10, p. 4182, doi. 10.1172/JCI68459
    By:
    • Hodson, David J.;
    • Mitchell, Ryan K.;
    • Bellomo, Elisa A.;
    • Gao Sun;
    • Vinet, Laurent;
    • Meda, Paolo;
    • Daliang Li;
    • Wen-Hong Li;
    • Bugliani, Marco;
    • Marchetti, Piero;
    • Bosco, Domenico;
    • Piemonti, Lorenzo;
    • Johnson, Paul;
    • Hughes, Stephen J.;
    • Rutter, Guy A.
    Publication type:
    Article
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    Goals of Treatment for Type 2 Diabetes.

    Published in:
    Diabetes Care, 2009, v. 32, p. S178, doi. 10.2337/dc09-S306
    By:
    • Marchetti, Piero;
    • Lupi, Roberto;
    • Del Guerra, Silvia;
    • Bugliani, Marco;
    • D'Aleo, Valentina;
    • Occhipinti, Margherita;
    • Boggi, Ugo;
    • Marselli, Lorella;
    • Masini, Matilde
    Publication type:
    Article
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    Direct effects of rosuvastatin on pancreatic human beta cells.

    Published in:
    Acta Diabetologica, 2013, v. 50, n. 6, p. 983, doi. 10.1007/s00592-013-0465-y
    By:
    • Bugliani, Marco;
    • Syed, Farooq;
    • Masini, Matilde;
    • Marselli, Lorella;
    • Suleiman, Mara;
    • Novelli, Michela;
    • Filipponi, Franco;
    • Boggi, Ugo;
    • Masiello, Pellegrino;
    • De Tata, Vincenzo;
    • Marchetti, Piero
    Publication type:
    Article
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    Fostering improved human islet research: a European perspective.

    Published in:
    2019
    By:
    • Marchetti, Piero;
    • Schulte, Anke M.;
    • Marselli, Lorella;
    • Schoniger, Eyke;
    • Bugliani, Marco;
    • Kramer, Werner;
    • Overbergh, Lut;
    • Ullrich, Susanne;
    • Gloyn, Anna L.;
    • Ibberson, Mark;
    • Rutter, Guy;
    • Froguel, Philippe;
    • Groop, Leif;
    • McCarthy, Mark I.;
    • Dotta, Francesco;
    • Scharfmann, Raphael;
    • Magnan, Christophe;
    • Eizirik, Decio L.;
    • Mathieu, Chantal;
    • Cnop, Miriam
    Publication type:
    Letter
    21

    Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.

    Published in:
    Diabetologia, 2018, v. 61, n. 8, p. 1780, doi. 10.1007/s00125-018-4629-8
    By:
    • Bellini, Lara;
    • Campana, Mélanie;
    • Rouch, Claude;
    • Chacinska, Marta;
    • Bugliani, Marco;
    • Meneyrol, Kelly;
    • Hainault, Isabelle;
    • Lenoir, Véronique;
    • Denom, Jessica;
    • Véret, Julien;
    • Kassis, Nadim;
    • Thorens, Bernard;
    • Ibberson, Mark;
    • Marchetti, Piero;
    • Blachnio-Zabielska, Agnieszka;
    • Cruciani-Guglielmacci, Céline;
    • Prip-Buus, Carina;
    • Magnan, Christophe;
    • Le Stunff, Hervé
    Publication type:
    Article
    22

    Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.

    Published in:
    Diabetologia, 2018, v. 61, n. 3, p. 641, doi. 10.1007/s00125-017-4500-3
    By:
    • Solimena, Michele;
    • Schulte, Anke M.;
    • Marselli, Lorella;
    • Ehehalt, Florian;
    • Richter, Daniela;
    • Kleeberg, Manuela;
    • Mziaut, Hassan;
    • Knoch, Klaus-Peter;
    • Parnis, Julia;
    • Bugliani, Marco;
    • Siddiq, Afshan;
    • Jörns, Anne;
    • Burdet, Frédéric;
    • Liechti, Robin;
    • Suleiman, Mara;
    • Margerie, Daniel;
    • Syed, Farooq;
    • Distler, Marius;
    • Grützmann, Robert;
    • Petretto, Enrico
    Publication type:
    Article
    23

    Mast cells infiltrate pancreatic islets in human type 1 diabetes.

    Published in:
    Diabetologia, 2015, v. 58, n. 11, p. 2554, doi. 10.1007/s00125-015-3734-1
    By:
    • Martino, Luisa;
    • Masini, Matilde;
    • Bugliani, Marco;
    • Marselli, Lorella;
    • Suleiman, Mara;
    • Boggi, Ugo;
    • Nogueira, Tatiane;
    • Filipponi, Franco;
    • Occhipinti, Margherita;
    • Campani, Daniela;
    • Dotta, Francesco;
    • Syed, Farooq;
    • Eizirik, Decio;
    • Marchetti, Piero;
    • Tata, Vincenzo
    Publication type:
    Article
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    The p66 redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.

    Published in:
    Diabetologia, 2015, v. 58, n. 6, p. 1260, doi. 10.1007/s00125-015-3563-2
    By:
    • Natalicchio, Annalisa;
    • Tortosa, Federica;
    • Labarbuta, Rossella;
    • Biondi, Giuseppina;
    • Marrano, Nicola;
    • Carchia, Emanuele;
    • Leonardini, Anna;
    • Cignarelli, Angelo;
    • Bugliani, Marco;
    • Marchetti, Piero;
    • Fadini, Gian;
    • Giorgio, Marco;
    • Avogaro, Angelo;
    • Perrini, Sebastio;
    • Laviola, Luigi;
    • Giorgino, Francesco
    Publication type:
    Article
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    Optical control of insulin release using a photoswitchable sulfonylurea.

    Published in:
    Nature Communications, 2014, v. 5, n. 10, p. 5116, doi. 10.1038/ncomms6116
    By:
    • Broichhagen, Johannes;
    • Schönberger, Matthias;
    • Cork, Simon C.;
    • Frank, James A.;
    • Marchetti, Piero;
    • Bugliani, Marco;
    • Shapiro, A. M. James;
    • Trapp, Stefan;
    • Rutter, Guy A.;
    • Hodson, David J.;
    • Trauner, Dirk
    Publication type:
    Article
    29

    LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03943-0
    By:
    • Cobo-Vuilleumier, Nadia;
    • Lorenzo, Petra I.;
    • García Rodríguez, Noelia;
    • de Gracia Herrera Gómez, Irene;
    • Fuente-Martin, Esther;
    • López-Noriega, Livia;
    • Manuel Mellado-Gil, José;
    • Romero-Zerbo, Silvana-Yanina;
    • Baquié, Mathurin;
    • Lachaud, Christian Claude;
    • Stifter, Katja;
    • Perdomo, German;
    • Bugliani, Marco;
    • De Tata, Vincenzo;
    • Bosco, Domenico;
    • Parnaud, Geraldine;
    • Pozo, David;
    • Hmadcha, Abdelkrim;
    • Florido, Javier P.;
    • Toscano, Miguel G.
    Publication type:
    Article
    30

    DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

    Published in:
    EMBO Journal, 2012, v. 31, n. 6, p. 1405, doi. 10.1038/emboj.2011.503
    By:
    • Volkmar, Michael;
    • Dedeurwaerder, Sarah;
    • Cunha, Daniel A;
    • Ndlovu, Matladi N;
    • Defrance, Matthieu;
    • Deplus, Rachel;
    • Calonne, Emilie;
    • Volkmar, Ute;
    • Igoillo-Esteve, Mariana;
    • Naamane, Najib;
    • Del Guerra, Silvia;
    • Masini, Matilde;
    • Bugliani, Marco;
    • Marchetti, Piero;
    • Cnop, Miriam;
    • Eizirik, Decio L;
    • Fuks, François
    Publication type:
    Article
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    ADCY5 Couples Glucose to Insulin Secretion in Human Islets.

    Published in:
    Diabetes, 2014, v. 63, n. 9, p. 3009, doi. 10.2337/db13-1607
    By:
    • Hodson, David J.;
    • Mitchell, Ryan K.;
    • Marselli, Lorella;
    • Pullen, Timothy J.;
    • Gimeno Brias, Silvia;
    • Semplici, Francesca;
    • Everett, Katy L.;
    • Cooper, Dermot M. F.;
    • Bugliani, Marco;
    • Marchetti, Piero;
    • Lavallard, Vanessa;
    • Bosco, Domenico;
    • Piemonti, Lorenzo;
    • Johnson, Paul R.;
    • Hughes, Stephen J.;
    • Daliang Li;
    • Wen-Hong Li;
    • Shapiro, A. M. James;
    • Rutter, Guy A.
    Publication type:
    Article
    37

    RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate.

    Published in:
    Diabetes, 2014, v. 63, n. 6, p. 1978, doi. 10.2337/db13-1383
    By:
    • Cnop, Miriam;
    • Abdulkarim, Baroj;
    • Bottu, Guy;
    • Cunha, Daniel A.;
    • Igoillo-Esteve, Mariana;
    • Masini, Matilde;
    • Turatsinze, Jean-Valery;
    • Griebel, Thasso;
    • Villate, Olatz;
    • Santin, Izortze;
    • Bugliani, Marco;
    • Ladriere, Laurence;
    • Marselli, Lorella;
    • McCarthy, Mark I.;
    • Marchetti, Piero;
    • Sammeth, Michael;
    • Eizirik, Décio L.
    Publication type:
    Article
    38

    Pleiotropic Effects of GIP on Islet Function Involve 0steopontin.

    Published in:
    Diabetes, 2011, v. 60, n. 9, p. 2424, doi. 10.2337/db10-1532
    By:
    • Lyssenko, Valeriya;
    • Eliasson, Lena;
    • Kotova, Olga;
    • Pilgaard, Kasper;
    • Wierup, Nils;
    • Salehi, Albert;
    • Wendt, Anna;
    • Jonsson, Anna;
    • De Marinis, Yang Z.;
    • Berglund, Lisa M.;
    • Taneera, Jalal;
    • Balhuizen, Alexander;
    • Hansson, Ola;
    • Osmark, Peter;
    • Dunér, Pontus;
    • Broøs, Charlotte;
    • Stančáková, Alena;
    • Kuusisto, Johanna;
    • Bugliani, Marco;
    • Saxena, Richa
    Publication type:
    Article
    39

    Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels.

    Published in:
    Diabetes, 2010, v. 59, n. 10, p. 2662, doi. 10.2337/db10-0389
    By:
    • Bouatia-Naji, Nabila;
    • Bonnefond, Amélie;
    • Baerenwald, Devin A.;
    • Marchand, Marion;
    • Bugliani, Marco;
    • Marchetti, Piero;
    • Pattou, François;
    • Printz, Richard L.;
    • Flemming, Brian P.;
    • Umunakwe, Obi C.;
    • Conley, Nicholas L.;
    • Vaxillaire, Martine;
    • Lantieri, Olivier;
    • Balkau, Beverley;
    • Marre, Michel;
    • Lévy-Marchal, Claire;
    • Elliott, Paul;
    • Jarvelin, Marjo-Riitta;
    • Meyre, David;
    • Dina, Christian
    Publication type:
    Article
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    Effects of C-peptide on isolated human pancreatic islet cells.

    Published in:
    Diabetes/Metabolism Research & Reviews, 2007, v. 23, n. 3, p. 215, doi. 10.1002/dmrr.674
    By:
    • Bugliani, Marco;
    • Torri, Scilla;
    • Lupi, Roberto;
    • Del Guerra, Silvia;
    • Grupillo, Maria;
    • Del Chiaro, Marco;
    • Mosca, Franco;
    • Boggi, Ugo;
    • Del Prato, Stefano;
    • Marchetti, Piero
    Publication type:
    Article
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    Are we overestimating the loss of beta cells in type 2 diabetes?

    Published in:
    Diabetologia, 2014, v. 57, n. 2, p. 362, doi. 10.1007/s00125-013-3098-3
    By:
    • Marselli, Lorella;
    • Suleiman, Mara;
    • Masini, Matilde;
    • Campani, Daniela;
    • Bugliani, Marco;
    • Syed, Farooq;
    • Martino, Luisa;
    • Focosi, Daniele;
    • Scatena, Fabrizio;
    • Olimpico, Francesco;
    • Filipponi, Franco;
    • Masiello, Pellegrino;
    • Boggi, Ugo;
    • Marchetti, Piero
    Publication type:
    Article